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| 1 | Cognitive improvement following transvenous adipose-derived mesenchymal stem cell transplantation in a rat model of traumatic brain injury显示文摘The effects of adipose-derived mesenchymal stem cell (ADMSC) transplantation for the repair of traumatic brain injury remain poorly understood. The present study observed neurological functional changes in a rat model of traumatic brain injury following ADMSC transplantation via the tail vein. Cell transplants were observed in injured cerebral cortex, and expression of brain-derived nerve growth factor was significantly increased in the injured hippocampus following transplantation. Results demonstrated that transvenous ADMSC transplants migrated to the injured cerebral cortex and significantly improved cognitive function. | Dongfei Li Chun Yang Rongmei Qu Huiying Yang Meichun Yu Hui Tao Jingxing Dai Lin Yuan | 2011 | Neural Regeneration Research2011，6，10： | 7 |
| 2 | Regulation of 1, 4, 5-triphosphate receptor channel gating dynamics by mutant presenilin in Alzheimer's disease cells显示文摘 | Fang Wei Xiang Li Meichun Cai Yanping Liu Peter Jung Jianwei Shuai | 2017 | Frontiers of physics2017，12，3： | 4 |
| 3 | Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer显示文摘Given that only a subset of patients with colorectal cancer(CRC)benefit from immune checkpoint therapy,efforts are ongoing to identify markers that predict immunotherapeutic response.Increasing evidence suggests that microbes influence the efficacy of cancer therapies.Fusobacterium nucleatum induces different immune responses in CRC with different microsatellite-instability(MSI)statuses.Here,we investigated the effect of F.nucleatum on anti-PD-L1 therapy in CRC.We found that high F.nucleatum levels correlate with improved therapeutic responses to PD-1 blockade in patients with CRC.Additionally,F.nucleatum enhanced the antitumor effects of PD-L1 blockade on CRC in mice and prolonged survival.Combining F.nucleatum supplementation with immunotherapy rescued the therapeutic effects of PD-L1 blockade.Furthermore,F.nucleatum induced PD-L1 expression by activating STING signaling and increased the accumulation of interferon-gamma(IFN-γ)^(+)CD8^(+)tumor-infiltrating lymphocytes(TILs)during treatment with PD-L1 blockade,thereby augmenting tumor sensitivity to PD-L1 blockade.Finally,patient-derived organoid models demonstrated that increased F.nucleatum levels correlated with an improved therapeutic response to PD-L1 blockade.These findings suggest that F.nucleatum may modulate immune checkpoint therapy for CRC. | Yaohui Gao Dexi Bi Ruting Xie Man Li Jing Guo Hu Liu Xianling Guo Juemin Fang Tingting Ding Huiyuan Zhu Yuan Cao Meichun Xing Jiayi Zheng Qing Xu Qian Xu Qing Wei Huanlong Qin | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 3 |
| 4 | Ab Initio Calculations of the Electronic Structures of Copper Pyrites CuS2, CuSe2 and CuTe2显示文摘The electronic structures of CuS2, CuSe2 and CuTe2 with pyrite structures, within the framework the density-functional theory have been investigated. The calculated results explained the recent experimental results which show that there is no clear indication of strong electron correlations in the electronic properties of Cu pyrites, due to the dominant chalcogen p character rather than d characteristic of Cu at the Fermi level. | Zhufeng HOU, Aiyu LI, Zizhong ZHU and Meichun HUANGDepartment of Physics, Xiamen University, Fujian 361005, China | 2004 | Journal of Materials Science & Technology2004，20，4： | 3 |
| 5 | Microbiota analysis revealed vertical transmission and microbial adjusting function of symbiotic fungus in the attelabid weevil fungiculture显示文摘Dear Editor,Microbial symbionts are crucial participants in the life history of fungus-farming insects (Mueller et al., 2005;Youngsteadt, 2008). The attelabid weevil (Euops chinensis)feeding on Fallopia japonica in southern China, has evolved a special proto-farming bipartite symbiosis with the fungus(Penicillium herquei), which produces antibiotic (+)-scleroderolide in the leaf-rolls ('cradle' for offspring development) to protect the offspring from potential microbial parasites and pathogens (Sakurai, 1985;Wang et al., 2015). | Bin Lin Lin Wang Muzammi Hussain Xiaoling Zhang Jianqing Tian Sha Qi Xingzhong Liu Meichun Xiang | 2019 | Science China(Life Sciences)2019，62，12： | 3 |
| 6 | How carnivorous fungi use three-celled constricting rings to trap nematodes显示文摘Predacious fungi form specialized hyphae structures to trap nematodes and other microscopic animals.Among the six kinds of trapping devices,the constricting ring is the only one that actively captures nematodes.When a nematode enters the aperture of the ring,which is formed by three cells,the cells rapidly triple their vol-ume,close the aperture and hold the nematode in place.Hyphae then penetrate and consume the nematode.This paper reviews the data and hypotheses on con-serving the evolution of constricting rings and their cytological and molecular mechanisms. | Keke Liu Jianqing Tian Meichun Xiang Xingzhong Liu | 2012 | Protein & Cell2012，3，5： | 2 |
| 7 | Two Pb(II) dicarboxylates constructed by rigid terephthalate or flexible d(+ )-camphorate with different 3D motif based on cooperative effect of steric hindrance of ligand and lone pair electrons 显示文摘 | TAN Yanxi WENG Fayan WU Meichun | 2009 | J Mol Struct2009，928，1： | 1 |
| 8 | T1 locus in cotton is the candidate gene affecting lint percentage, fiber quality and spiny bollworm (Earias spp.) resistance显示文摘 | Qun Wan Zhengsheng Zhang Meichun Hu Li Chen Dajun Liu Xiao Chen Wei Wang Jing Zheng | 2007 | Euphytica (-)2007，，1： | 1 |
| 9 | Immunomodulatory effect of exo-polysaccharides from submerged cul- tured Cordyceps sinensis: enhancement of cytokine synthesis, CD 11 b expression, and phagocytosis显示文摘 | KUO Meichun CHANG Chienyu CHENG Tsolin | 2007 | Appl Micrnhiol Biotechnol2007，75，4： | 1 |
| 10 | The twinning project makes a difference: ETNEP in China显示文摘 | Wang Lingyan Zheng Meichun | 2006 | World Council of Enterostomal Therapists Journal2006，26，3： | 1 |
| 11 | In-phase alignments of asymmetric building units in Ln4GaSbS9 (Ln:Pr, Nd, Sm, Gd- Ho) and their strong nonlinear optical responses in middle IR显示文摘 | Chen Meichun Li Longhua Chen Yubiao | 2011 | J Am Chem Soc2011，133，12： | 1 |
| 12 | Disconnection enhances the second harmonic generation response: synthesis and characteriza- tion of Baz3GasSbzS38显示文摘 | Chen Meichun Wu Liming Lin Hua | 2012 | JAmChern Soc2012，134，14： | 1 |
| 13 | Cellulose nanoparticles as modifiers for rheology and fluid loss in bentonite water-based fluids显示文摘 | LI Meichun WU Qinglin SONG Kunlin | 2015 | Applied Materials & Interfaces2015，7，8： | 1 |
| 14 | Structure change induced by terminal sulfur in noncentrosymmetric La2Ga2GeSs and Eu2Ga2 GeS7 and nonlinear-optical responses in middle infrared显示文摘 | Chen Meichun Li Peng Zhou Liujiang | 2011 | Inorg Chem2011，50，12： | 1 |
| 15 | Effects and mecha- nisms of aloe-emodin on cell death in human lung squa- mous cell carcinoma 显示文摘 | Lee HZ Hsu SL Liu Meichun | 2001 | Eur J Pharmacol2001，431，3： | 1 |
| 16 | Experimental Research on Square Steel Tubular Columns Filled with Steel-Rein- forced Self-Consolidatlng HighoStrength Concrete Under Axial Load 显示文摘 | Zhu Meichun Liu Jianxin Wang Qingxiang | 2010 | Engineering Structures2010，32，8： | 1 |
| 17 | Isolation and characterization of Jingzhaotoxin-V, a novel neurotoxin from the venom of the spider Chilobrachys jingzhao显示文摘 | Xiongzhi Zeng Meichun Deng Ying Lin Chunhua Yuan Jianhui Pi Songping Liang | 2007 | Toxicon2007，49，3： | 1 |
| 18 | High-performance flexible all-solid-state asymmetric supercapacitors based on binder-free MXene/cellulose nanofiber anode and carbon cloth/polyaniline cathode显示文摘The search for wearable electronics has been attracted great efforts,there is an ever-growing demand for all-solid-state flexible energy storage devices.However,it is a challenge to obtain both positive and negative electrodes with excellent mechanical strength and match positive and negative charges to achieve high energy densities and operate voltages to satisfy practical application requirements.Here,flexible MXene(Ti_(3)C_(2)Tx)/cellulose nanofiber(CNF)composite film negative electrodes(MCNF)were fabricated with a vacuum filtration method,as well as positive electrodes(CP)by combining polyaniline(PANI)with carbon cloth(CC)using an in-situ polymerization method.Both positive and negative free-standing electrodes exhibited excellent electrochemical behavior and bendable/foldable flexibility.As a result,the all-pseudocapacitance asymmetric device of MCNF//CP assembled with charge-matched between anode and cathode achieves an extended voltage window of 1.5 V,high energy density of 30.6 Wh·kg^(−1)(1211 W·kg^(−1)),86%capacitance retention after 5000 cycles,the device maintains excellent bendability,simultaneously.This work will pave the way for the development of all-pseudocapacitive asymmetric supercapacitors(ASC)with simultaneously preeminent mechanical properties,high energy density,wide operating voltage window. | Xiaoyu Bi Meichun Li Guoqiang Zhou Chaozheng Liu Runzhou Huang Yang Shi Ben Bin Xu Zhanhu Guo Wei Fan Hassan Algadi Shengbo Ge | 2023 | Nano Research2023，16，5： | 1 |
| 19 | Preparation and Characterization of Nanocrystalline Cellulose/Poly(lactic acid) Composite Membranes显示文摘Nanocrystalline cellulose(NCC)/poly(lactic acid)(PLLA) composite membranes were prepared by the solution casting method.Physical and chemical modifications were performed to improve the compatibility of NCC and PLLA.The results indicated that the NCC dispersibility of the composite membranes with chemical modification were superior to that of the composite membranes with physical modification.Moreover,the chemical modification NCC not only had a large effect on the nucleation and growth of the crystals,but also affected the crystal forms of PLLA.This was because chemical reactions took place between the silicone of silane coupling agent(KH-570) and the hydroxyl groups of NCC during blending.The chemical modification NCC could be dispersed stably in the PLLA matrix,and it played the role of a nucleating agent. | MeiChun Ding ChenWei Li FuShan Chen | 2017 | Paper And Biomaterials2017，2，3： | 1 |
| 20 | Applying latent tree analysis to classify Traditional Chinese Medicine syndromes(Zheng)in patients with psoriasis vulgaris显示文摘OBJECTIVE:To treat patients with psoriasis vulgaris using Traditional Chinese Medicine(TCM),one must stratify patients into subtypes(known as TCM syndromes or Zheng)and apply appropriate TCM treatments to different subtypes.However,no unified symptom-based classification scheme of subtypes(Zheng)exists for psoriasis vulgaris.The present paper aims to classify patients with psoriasis vulgaris into different subtypes via the analysis of clinical TCM symptom and sign data.METHODS:A cross-sectional survey was carried out in Beijing from 2005-2008,collecting clinical TCM symptom and sign data from 2764 patients with psoriasis vulgaris.Roughly 108 symptoms and signs were initially analyzed using latent tree analysis,with a selection of the resulting latent variables then used as features to cluster patients into subtypes.RESULTS:The initial latent tree analysis yielded a model with 43 latent variables.The second phase of the analysis divided patients into three subtype groups with clear TCM Zheng connotations:'blood deficiency and wind dryness';'blood heat';and'blood stasis'.CONCLUSIONS:Via two-phase analysis of clinic symptom and sign data,three different Zheng subtypes were identified for psoriasis vulgaris.Statistical characteristics of the three subtypes are presented.This constitutes an evidence-based solution to the syndromedifferentiation problem that exists with psoriasis vulgaris. | XU Wenjie ZHANG Nevin L. LI Ping WANG Tianfang CHEN Weiwen LIU April H. MOHLER-KUO Meichun | 2022 | Journal of Traditional Chinese Medicine2022，42，1： | 1 |
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