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| 1 | Research Trend on Patent Analysis:An Analysis of the Research Published in Library's Electronic Databases显示文摘 | KueiKuei Lai MeiLan Lin ShuMin Chang | 2006 | The Journal of American Academy of Business2006，8，2： | 1 |
| 2 | Schwarz intraspecific diversity of vibrio vulnfficus in galveston bay water and dysters as determined by randomly amplified polymorphic DNA PCR显示文摘 | Lin Meilan Deborah A | 2003 | Appl Envir Microbiol2003，69，6： | 1 |
| 3 | Docosahexaenoic acid inhibited the Wnt/β-Catenin pathway and suppressed breast cancer cells in vitro and in vivo显示文摘 | Meilan Xue Qing Wang Jinglan Zhao Liyan Dong Yinlin Ge Lin Hou Yongchao Liu Zheng Zheng | 2013 | The Journal of Nutritional Biochemistry2013，，： | 1 |
| 4 | Flower development and sexual dimorphism in Vernicia montana显示文摘The mu oil tree(Vernicia montana Lour.) is a dioecious species, but the genetic mechanisms underlying its phenotypic sexual dimorphism are unclear. In this study, we determined two pivotal phases of sex differentiation of mu oil tree via morphological and histological analyses of unisexual flowers:(Ⅰ) differentiation of male or female primordia to produce staminate flowers(SFs) or transient hermaphrodite flowers(HFs),and(Ⅱ) complete abortion of stamens in transient HFs to generate pistillate flowers(PFs). A total of 1621 sex-biased genes were identified by comparative transcriptome analysis which exhibited elevated rates of protein evolution than unbiased genes. The female-biased genes were enriched in the production of defense compounds while male-biased genes were focused on the production of viable pollens. Transcriptomebased analysis revealed that the differentially expressed genes(DEGs) between PFs and SFs in phase Ⅰ involved in abscisic acid(ABA), auxin(AUX), cytokinin(CK), ethylene(ET), and gibberellin(GA) biosynthesis and signaling showed higher expression levels in males than in females in general, whereas the DEGs involved in jasmonic acid(JA) and salicylic acid(SA) pathways displayed opposite expression patterns. Moreover,differentially expressed endogenous ABA, AUX, GAs, JA, and SA exhibited consistent biased expression patterns with the DEGs by UPLC-MSbased analysis. Exogenous application of an anti-ethylene plant growth regulator could promote the development of stamens in PFs and generated HFs. Comparative transcriptomic and hormonal analyses of PFs and SFs in phase Ⅱ indicated an increase in ET concentration when abortion of stamens in PFs occurred. This study suggested that phytohormones play key roles in sex dimorphism and ET may determine the development of stamens in PFs of mu oil tree, which provides an insight into plant sex differentiation mechanisms. | Wenying Li Jingzhen Chen Xiang Dong Meilan Liu Guibin Wang Lin Zhang | 2024 | Horticultural Plant Journal2024，10，2： | 0 |
| 5 | Biophysical characterization of oligomerization and fibrillization of the G131V pathogenic mutant of human prion protein显示文摘The pathogenesis of fatal neurodegenerative prion diseases is closely associated with the conversion of a-helix-rich cellular prion protein into p-sheet-rich scrapie form.Pathogenic point mutations of prion proteins usually promote the conformational conversion and trigger inherited prion diseases.The G131V mutation of human prion protein(HuPrP)was identified to be involved in Gerstmann-Straussler-Scheinker syndrome.Few studies have been carried out to address the pathogenesis of the G131V mutant.Here,we addressed the effects of the G131V mutation on oligomerization and fibrillization of the full-length HuPrP(23-231)and truncated HuPrP(91-231)proteins.The G131V mutation promotes the oligomerization but alleviates the fibrillization of HuPrE implying that the oligomerization might play a crucial role in the pathogenic mechanisms of the G131V mutant.Moreover,the flexible N-terminal fragment in either the wild-type or the G131V mutant HuPrP in creases the oligomerizati on tenden cies but decreases the fibrillizati on tendencies.Furthermore,this mutation significantly alters the tertiary structure of human PrPc and might distinctly ch a nge the conformati onal conversion tendency.Interestingly,both gua ni?dine hydrochloride denaturation and thermal denaturation experiments showed that the G131V mutation does not sign ificantly ch a nge the thermodynamic stabilities of the HuPrP protei ns.This work may be of ben efit to a mecha nistic un derstandi ng of the conformational con version of prion proteins and also provide clues for the prevention and treatment of prion diseases. | Meilan Zhang Haoran Zhang Hongwei Yao Chenyun Guo Donghai Lin | 2019 | Acta Biochimica et Biophysica Sinica2019，51，12： | 0 |
| 6 | The role of salicylic acid in plant flower development显示文摘Salicylic acid(SA),belonging to a family of naturally occurring phenolic compounds,is a crucial plant hormone involved in many biological processes,such as plant immunity,seed germination,root initiation,stomatal closure,and biotic/abiotic stress response.SA playing central roles in many metabolic processes have been extensively characterized.However,the function of SA in plant flower development has rarely been investigated.This paper reviews recent research advances on the roles of SA in flower development,including regulation of stamen development,flowering time,and ovarian development.This study provides multiple lines and levels of evidence substantiating that SA plays important roles in flower development,and suggests a pressing need to study the flower development-related functions of SA in both annual and perennial plants. | Ying Luo Meilan Liu Jie Cao Fuliang Cao Lin Zhang | 2022 | Forestry Research2022，2，1： | 0 |
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