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| 1 | Utility of magnetic resonance imaging in anorectal disease显示文摘Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily. CT scanning and endorectal ultrasound have become popular in assessment of anatomy and staging of tumors, but have limitations. Magnetic resonance imaging (MRI) has the capability to fill in the gaps left open by more conventional imaging modalities and continues to be promising as the definitive imaging technique in the pelvis, especially with advancement of emerging technologies in this field. A comprehensive review of this topic has been undertaken. Anorectal disease is divided into three broad categories: cancer, fistula/abscess, and pelvic floor disorders. A review of the literature is performed to evaluate the use of MRI and other imaging modalities in these three areas. Preoperative imaging is useful in the evaluation of all three areas of anorectal disease. MRI is an effective tool in delineating anatomy and, when correlating with the specific clinical scenario, is an effective adjunct in clinical decision-making in order to optimize outcome. MRI continues to be a promising and novel approach to imaging various afflictions of the anorectum and the pelvic floor. Its role is more well-established in some areas than in others, and there are still signif icant limitations. As technology advances, MRI will shed more light on a complex anatomical area. | Loren Berman Gary M Israel Shirley M McCarthy Jeffrey C Weinreb Walter E Longo | 2007 | World Journal of Gastroenterology2007，13，23： | 11 |
| 2 | 美国修改国内埃博拉疫情应对措施显示文摘埃博拉病毒是引起人类和灵长类动物发生埃博拉出血热的烈性病毒,其引起的埃博拉出血热是当今世界上致命的病毒性出血热,感染者症状与同为纤维病毒科的马尔堡病毒极为相似,包括恶心、呕吐、腹泻、肤色改变、全身酸痛、体内出血、体外出血、发热等。埃博拉病毒生物安全等级为4级(艾滋病为3级,SARS为3级,级数越大防护越严格)。病毒潜伏期可达2~21 d。经肠道、非胃肠道或鼻内途径均可造成感染,感染后2~5 d出现高热,6~9 d死亡。2014年2月新一轮埃博拉疫情在几内亚被发现,西非国家正呈加速蔓延之势,2014年9月17日,世界卫生组织官员称,西非地区已有超过3 000人因感染埃博拉病毒死亡,病毒感染超过5 000人。2014年8月2日美国接感染埃博拉病毒的医生回国治疗,9月30日美国本土确认第1例埃博拉病毒感染者,10月16日确诊第2例埃博拉病毒感染者,10月20日美国疾病控制和预防中心发布了新版医务人员处理埃博拉出血热患者的安全防护指南。 | McCarthy M 本刊编辑部 | 2014 | 中国全科医学2014，17，36： | 7 |
| 3 | Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes - Association analyses in 9,518 subjects显示文摘 | Owen, KR Groves, CJ Hanson, RL Knowler, WC Shuldiner, AR Elbein, SC Mitchell, BD Froguel,P Ng, MCY Chan, JC Jia, WP Deloukas, P Hitman, GA Walker, M Frayling, TM Hattersley, AT Zeggini, E McCarthy, MI | 2007 | 中国生物学文摘2007，21，11： | 2 |
| 4 | Functional magnetic resonance imaging in a visual oddball task显示文摘 | McCarthy G Luby M Gore JC | 1996 | Neuroimage1996，3，： | 2 |
| 5 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 6 | Enzymatic Degradability of Poly(lactide) :Effects of chain stereochemistry and material crystallinity 显示文摘 | REEVE M MCCARTHY S P GROSS R A | 1996 | Macromolecules1996，29，23： | 1 |
| 7 | The role of cholecystokinin in interlcukin-1-induced anorexia显示文摘 | DAUN J M MCCARTHY D O | 1993 | Physiol Behav1993，54，： | 1 |
| 8 | Strategic environmental assessment:The potential for development in South Australia显示文摘 | McCarthy M | 1996 | Project Appraisal1996，11，3： | 1 |
| 9 | Internet Monitoring of Suicide Risk in the Population显示文摘 | McCarthy M J | 2010 | Journal of Affective Disorders2010，122，： | 1 |
| 10 | Intra-event variability of Escherichia coli and total suspended solids in ur- ban stormwater runoff显示文摘 | McCarthy D T Hathaway J M Hunt W F | 2012 | Water Research2012，46，20： | 1 |
| 11 | Perceptions of Contractual Risk Alloca- tion in Construction Supply Chains 显示文摘 | Loosemore M McCarthy C S | 2008 | Journal of Professional Issues in Engineering Education and Practice2008，134，1： | 1 |
| 12 | The economics of obesity 显示文摘 | MCCARTHY M | 2004 | The Lancet2004，364，9452： | 1 |
| 13 | Preliminary Views on the Potential of Foamed Concrete as a Structural Material显示文摘 | Jones M R McCarthy A | 2005 | Magazine of Con crete Research2005，57，1： | 1 |
| 14 | Mdeling of Bird Strike on an Aircraft wing Leading Edge Made from Fiber Metal Laminates Partl : Material Modeling 显示文摘 | McCarthy M A Xiao J R Petrinic C T | 2004 | Aplied Com- posite Materials2004，11，5： | 1 |
| 15 | Pediatric diffuse large B - cell lymphoma demonstrates a high proliferation index, frequent c - Myc protein expression, and a high incidence of germinal center subtype: Report of the French - American - British ( FAB ) international study group 显示文摘 | Miles RR Raphael M McCarthy K | 2008 | Pediatr Blood Cancer2008，51，3： | 1 |
| 16 | Strategic environmental assessment: The potential for development in South Australia显示文摘 | McCarthy M | 1996 | Project Appraisal1996，11，3： | 1 |
| 17 | Diagnosis of acute flank pain:value of unenhanced helical CT显示文摘 | Smith RC Verga M McCarthy S | 1996 | Am J Radiol1996，166，： | 1 |
| 18 | State space modeling of price and volume dependence: evidence from currency futures显示文摘 | Mccarthy J Najand M | 1993 | The Journal of Futures Markets1993，13，： | 1 |
| 19 | Aging and mieroRNA expression in human skeletal muscle: a microarray and bioinformatics analysis 显示文摘 | DRUMMOND M J MCCARTHY J J SINHA M | 2011 | Physiol Genome2011，43，10： | 1 |
| 20 | 1 l-Ketotigogenin cellobioside (pamaqueside): a potent cholesterol absorption inhibitor in the hamster显示文摘 | McCarthy P A DeNinno M P Morehouse L A | 1996 | J Med Chem1996，39，10： | 1 |
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