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5篇 您的检索式:作者名="Max ROBINSON"
    题名 作者 年代 出处 被引量
1A new system for sternal intraosseous infusion in adults显示文摘Andrew Macnab Jim Christenson Judy Findlay Bruce Horwood David Johnson Lanny Jones Kelly Phillips Charles Pollack David J. Robinson Chris Rumball Tom Stair Brian Tiffany Max Whelan 2000Prehospital Emergency Care2000,,2:1
2Entrepreneurship Education in America's Major Universities显示文摘Peter Robinson Max Haynes 0,,01:1
3Chemical identification of N-acyl homoserine lactone quorum-sensing signals produced by Sinorhizobium meliloti strains in defined medium显示文摘Max Teplitski Anatol Eberhard Matthew R. Gronquist Mengsheng Gao Jayne B. Robinson Wolfgang D. Bauer 2003Archives of Microbiology2003,,6:1
4Angiotensin-Converting Enzyme(ACE)Inhibitors May Moderate COVID-19 Hyperinflammatory Response:An Observational Study with Deep Immunophenotyping显示文摘Background:Angiotensin-converting enzyme inhibitors(ACEi)and angiotensin-II receptor blockers(ARB),the most commonly prescribed antihypertensive medications,counter renin-angiotensin-aldosterone system(RAAS)activation via induction of angiotensin-converting enzyme 2(ACE2)expression.Considering that ACE2 is the functional receptor for SARS-CoV-2 entry into host cells,the association of ACEi and ARB with COVID-19 outcomes needs thorough evaluation.Methods:We conducted retrospective analyses using both unmatched and propensity score(PS)-matched cohorts on electronic health records(EHRs)to assess the impact of RAAS inhibitors on the risk of receiving invasive mechanical ventilation(IMV)and 30-day mortality among hospitalized COVID-19 patients.Additionally,we investigated the immune cell gene expression profiles of hospitalized COVID-19 patients with prior use of antihypertensive treatments from an observational prospective cohort.Results:The retrospective analysis revealed that there was no increased risk associated with either ACEi or ARB use.In fact,the use of ACEi showed decreased risk for mortality.Survival analyses using PS-matched cohorts suggested no significant relationship between RAAS inhibitors with a hospital stay and in-hospital mortality compared to non-RAAS medications and patients not on antihypertensive medications.From the analysis of gene expression profiles,we observed a noticeable up-regulation in the expression of 1L1R2(an anti-inflammatory receptor)and RETN(an immunosuppressive marker)genes in monocytes among prior users of ACE inhibitors.Conclusion:Overall,the findings do not support the discontinuation of ACEi or ARB treatment and suggest that ACEi may moderate the COVID-19 hyperinflammatory response.Venkata R.Duvvuri Andrew Baumgartner Sevda Molani Patricia V.Hernandez Dan Yuan Ryan T.Roper Wanessa F.Matos Max Robinson Yapeng Su Naeha Subramanian Jason D.Goldman James R.Heath Jennifer J.Hadlock 2022Health Data Science2022,,1:1
5A Rare Case of Non-small Cell Lung Carcinoma Squamous Phenotype with Epstein-Barr Virus Positivity with Prolonged Response to both Chemotherapy and Radiotherapy显示文摘We present a rare challenging case of metastatic non-small cell lung cancer with Epstein-Barr virus positivity that was also diagnosed with pulmonary tuberculosis at the same time. Palliative chemotherapy gemcitabine and carboplatin was started after two weeks of anti-tuberculosis treatment with the hopes that this period would be sufficient to keep acid fast bacilli non-viable to minimise risk of tuberculosis re-activation due to chemotherapy induced immunosuppression. She completed four cycles of chemotherapy and six months of anti-tuberculosis treatment with good results and minimal side effects. Two years later, there was disease recurrence in cervical and mediastinal lymph nodes which was treated with local treatment i.e. surgery and palliative radiotherapy. It has been two years since last radiotherapy and overall more than five years since diagnosis with no active disease at present. Given the complexity and rarity of this case, significant multidisciplinary team involvement, including oncologists and radiation oncologists, pulmonologists with special interest in tuberculosis and pathologists was necessary throughout.Carolina Navarro RODRIGUEZ Muhammad Shahid IQBAL Max ROBINSON Graham BURNS Alastair GREYSTOKE 2021中国肺癌杂志2021,24,7:0
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