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4篇 您的检索式:作者名="Matteo Pozzi"
    题名 作者 年代 出处 被引量
1Betting on Sport 显示文摘Lucio Colantuoni Cristiano Novazio Alessandro Izar Matteo Pozzi 2010International Sports Law Review Pandektis2010,,8:1
2Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives显示文摘Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and characterized by the degeneration of motor neurons.Amyotrophic lateral sclerosis is the most common and aggressive form of motor neuron disease with no effective treatment so far.Unfortunately,diagnostic and prognostic biomarkers are lacking in clinical practice.Neurofilaments are fundamental structural components of the axons and neurofilament light chain and phosphorylated neurofilament heavy chain can be measured in both cerebrospinal fluid and serum.Neurofilament light chain and phosphorylated neurofilament heavy chain levels are elevated in amyotrophic lateral sclerosis,reflecting the extensive damage of motor neurons and axons.Hence,neurofilaments are now increasingly recognized as the most promising candidate biomarker in amyotrophic lateral sclerosis.The potential usefulness of neurofilaments regards various aspects,including diagnosis,prognosis,patient stratification in clinical trials and evaluation of treatment response.In this review paper,we review the body of literature about neurofilaments measurement in amyotrophic lateral sclerosis.We also discuss the open issues concerning the use of neurofilaments clinical practice,as no overall guideline exists to date;finally,we address the most recent evidence and future perspectives.Yuri Matteo Falzone Tommaso Russo Teuta Domi Laura Pozzi Angelo Quattrini Massimo Filippi Nilo Riva 2021Neural Regeneration Research2021,16,10:1
3Non-hyperfunctioning neuroendocrine tumours of the pancreas: MR imaging appearance and correlation with their biological behaviour显示文摘Riccardo Manfredi Matteo Bonatti William Mantovani Rossella Graziani Diego Segala Paola Capelli Giovanni Butturini Roberto Pozzi Mucelli 2013European Radiology2013,,11:1
4Revaluation of clinical and histological criteria for diagnosis of dysmetabolic iron overload syndrome显示文摘AIM: To re-evaluate the diagnostic criteria of insulin resistance hepatic iron overload based on clinical, biochemical and histopathological findings. METHODS: We studied 81 patients with hepatic iron overload not explained by known genetic and acquired causes. The metabolic syndrome (MS) was defined according to ATPⅢ criteria. Iron overload was assessed by liver biopsy. Liver histology was evaluated by Ishak's score and iron accumulation by Deugnier's score; steatosis was diagnosed when present in ≥ 5% of hepatocytes. RESULTS: According to transferrin saturation levels, we observed significant differences in the amount of hepatic iron overload and iron distribution, as well as the number of metabolic abnormalities. Using Receiving Operating Curve analysis, we found that the presence of two components of the MS differentiatedtwo groups with a statistically significant different hepatic iron overload (P < 0.0001). Patients with ≥ 2 metabolic alterations and steatosis had lower amount of hepatic iron, lower transferrin saturation and higher sinusoidal iron than patients with < 2 MS components and absence of steatosis. CONCLUSION: In our patients, the presence of ≥ 2 alterations of the MS and hepatic steatosis was associated with a moderate form of iron overload with a prevalent sinusoidal distribution and a normal transferrin saturation, suggesting the existence of a peculiar pathogenetic mechanism of iron accumulation. These patients may have the typical dysmetabolic iron overload syndrome. By contrast, patients with transferrin saturation ≥ 60% had more severe iron overload, few or no metabolic abnormalities and a hemochromatosis-like pattern of iron overload.Alessia Riva Paola Trombini Raffaella Mariani Alessandra Salvioni Sabina Coletti Silvia Bonfadini Valentina Paolini Matteo Pozzi Rita Facchetti Giorgio Bovo Alberto Piperno 2008World Journal of Gastroenterology2008,14,30:0
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