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| 1 | Worldwide trends in gastric cancer mortality (1980–2011), with predictions to 2015, and incidence by subtype显示文摘 | Ana Ferro Bárbara Peleteiro Matteo Malvezzi Cristina Bosetti Paola Bertuccio Fabio Levi Eva Negri Carlo La Vecchia Nuno Lunet | 2014 | European Journal of Cancer2014，，： | 3 |
| 2 | High body mass index predicts multiple prostate cancer lymph node metastases after radical prostatectomy and extended pelvic lymph node dissection显示文摘Our aim is to evaluate the association between body mass index(BMI)and preoperative total testosterone(TT)levels with the risk of single and multiple metastatic lymph node invasion(LNI)in prostate cancer patients undergoing radical prostatectomy and extended pelvic lymph node dissection.Preoperative BMI,basal levels of TT,and prostate-specific antigen(PSA)were evaluated in 361 consecutive patients undergoing radical prostatectomy with extended pelvic lymph node dissection between 2014 and 2017・Patients were grouped into either nonmetastatic,one,or more than one metastatic lymph node invasion groups.The association among clinical factors and LNI was evaluated.LNI was detected in 52(14.4%)patients:28(7.8%)cases had one metastatic node and 24(6.6%)had more than one metastatic node.In the overall study population,BMI correlated inversely with TT(r=-0.256;P<0.0001).In patients without metastases,BMI inversely correlated with TT(r=-0.282;P<0.0001).In patients with metastasis,this correlation was lost.In the overall study population,BMI(odds ratio[OR]=1.268;P=0.005)was the only in dependent clinical factor associated with the risk of multiple metastatic LNI compared to cases with one metastatic node.In the nonmetastatic group,TT was lower in patients with BMI>28 kg m^2(P<0.0001).In patients with any LNI,this association was lost(P=0.232).The median number of positive nodes was higher in patients with BMI>28 kg m^2(P-0.048).In our study,overweight and obese patients had a higher risk of harboring multiple prostate cancer lymph node metastases and lower TT levels when compared to patients with normal BMI. | Antonio B Porcaro Alessandro Tafuri Marco Sebben Tania Processali Marco Pirozzi Nelia Amigoni Riccardo Rizzetto Aliasger Shakir Maria Angela Cerruto Matteo Brunelli Salvatore Siracusano Walter Artibani | 2020 | Asian Journal of Andrology2020，22，3： | 3 |
| 3 | Lithium beyond psychiatric indications:the reincarnation of a new old drug显示文摘Lithium has been used in the treatment of bipolar disorders for decades,but the exact mechanisms of action remain elusive to this day.Recent evidence suggests that lithium is critically involved in a variety of signaling pathways affecting apoptosis,inflammation,and neurogenesis,all of which contributing to the complex pathophysiology of various neurological diseases.As a matter of fact,preclinical work reports both acute and longterm neuroprotection in distinct neurological disease models such as Parkinson’s disease,traumatic brain injury,Alzheimer’s disease,and ischemic stroke.Lithium treatment reduces cell injury,decreasesα‑synuclein aggregation and Tau protein phosphorylation,modulates inflammation and even stimulates neuroregeneration under experimental conditions of Parkinson’s disease,traumatic brain injury,and Alzheimer’s disease.The therapeutic impact of lithium under conditions of ischemic stroke was also studied in numerous preclinical in vitro and in vivo studies,giving rise to a randomized double-blind clinical stroke trial.The preclinic data revealed a lithium-induced upregulation of anti-apoptotic proteins such as B-cell lymphoma 2,heat shock protein 70,and activated protein 1,resulting in decreased neuronal cell loss.Lithium,however,does not only yield postischemic neuroprotection but also enhances endogenous neuroregeneration by stimulating neural stem cell proliferation and by regulating distinct signaling pathways such as the RE1-silencing transcription factor.In line with this,lithium treatment has been shown to modulate postischemic cytokine secretion patterns,diminishing microglial activation and stabilizing blood-brain barrier integrity yielding reduced levels of neuroinflammation.The aforementioned observations culminated in a first clinical trial,which revealed an improved motor recovery in patients with cortical stroke after lithium treatment.Beside its well-known psychiatric indications,lithium is thus a promising neuroprotective candidate for the aforementioned neurological diseases.A detailed understanding of the lithium-induced mechanisms,however,is important for prospective clinical trials which may pave the way for a successful benchto-bedside translation in the future.In this review,we will give an overview of lithiuminduced neuroprotective mechanisms under various pathological conditions,with special emphasis on ischemic stroke. | Matteo Haupt Mathias Bähr Thorsten R.Doeppner | 2021 | Neural Regeneration Research2021，16，12： | 2 |
| 4 | Oncocytic papillary re- nal cell carcinoma:a clinicopathologic, immunohistochemi- cal, uhrastructural, and interphase cytogenetic study of 12 cases 显示文摘 | Ondrej H Matteo B Michal M | 2006 | Anna Diagn Pathol2006，10，： | 1 |
| 5 | Validation of an antbsphingosine-l-phos- phate antibody as a potential therapeutic in reducing growth, invasion,and angiogenesis in multiple tumor lineages显示文摘 | Visentin B Vekich J A Sibbald B J Cavalli A L Moreno K M Matteo R G | 2006 | Canc- er Cell2006，9，： | 1 |
| 6 | Intraoperative effects of combined versus general anesthesia during major liver surgery 显示文摘 | Siniscalchi A Begliomini B Matteo G | 2003 | Minerva Anestesiol2003，69，12： | 1 |
| 7 | Analysis of green tea catechins: comparative study between HPLC and HPCE显示文摘 | MATTEO B MARCO P TULLIA G Y | 2003 | Food Chemistry2003，81，4： | 1 |
| 8 | Assessment and treatment of elderly patients with cancer 显示文摘 | Lodovico B Giuseppe C Matteo C | 2010 | Surgical Oncology2010，19，： | 1 |
| 9 | The crystal structure of PGIP (polygalacturonase-inhibiting protein), a leucine-rich repeat protein involved in plant defense 显示文摘 | Di Matteo A Federici L Mattei B Salvi G Johnson K A Savino C DeLorenzo G Tsernoglou D Cervone F | 2003 | Proc Natl Acad Sci2003，100，10： | 1 |
| 10 | Hardwarein-the-Loop Approach for Redundant Bmshless Motor Control System显示文摘 | B Alessandro P Paolo T Luea M Matteo | 2006 | IECON 2006-32nd Annual Conference on IEEE Industrial Electronics2006，，： | 1 |
| 11 | Knowledge and attitudesabout cancer pain management : A national survey of Italian on-cologY nurses 显示文摘 | Matteo B Gianluca C Annie L et (27 | 2007 | European Journal of Oncology Nursing2007，11，： | 1 |
| 12 | Fast Determination of Catechins and Xanthines in Tea Beverages by Micellar Electrokinetic Chromatography显示文摘 | Matteo B Piero C Marco P | 2003 | J Agric Food Chem2003，51，： | 1 |
| 13 | Fusing appearance and distri- bution information of interest points for action recognition 显示文摘 | B Matteo X Tao G Shaogang | 2011 | Pattern Recognition2011，45，3： | 1 |
| 14 | Knowledge and attitudes about cancer pain management:A national survey of Italian oncology nurses显示文摘 | Matteo B Gianluca C Annie L | 2007 | European Journal of Oncology Nursing2007，11，： | 1 |
| 15 | Impact of diabetes and hy- pertension on left ventricular longitudinal systolic function显示文摘 | Piercarlo B Matteo C Sergio M | 2010 | Di- abetes Research and Clinical Practice2010，90，9： | 1 |
| 16 | On Ant Routing Algorithms in Ad Hoc Networks with Critical Connectivity 显示文摘 | Laura R Matteo B Cgianluca R | 2008 | Ad Hoc Network Journal2008，6，6： | 1 |
| 17 | Deletion of Trk B in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior显示文摘 | Matteo B Roberto R Spartaco S | 2008 | Proceedings of the National Academy of Sciences of the United States of America2008，105，15： | 1 |
| 18 | Single-plug autologous osteochondral transplantation:results at minimum 16yearsfollow-up显示文摘 | Filardo G Kon E Di Matteo B | 2014 | Orthopedics2014，37，9： | 1 |
| 19 | Benefits of laparoscopic colorectal resection are more pronounced in elderly patients 显示文摘 | Matteo F Marco B Andrea V | 2008 | Dis Colon Rectum2008，51，3： | 1 |
| 20 | Platelet rich plasma: a valid augmentation for cartilage scaffolds? A systematic review显示文摘 | Perdisa F Filardo G Di Matteo B | 2014 | Histol Histopathol2014，29，7： | 1 |
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