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| 1 | Tribology of Ti6Al4V: A review显示文摘The deleterious innate attribute of Ti6 Al4 V, the workhorse material among the alloy series of titanium is its incompetent tribo-behavior. Infinite surface modification techniques, viz., the accretion of adherent appendage layers, diffusion hardening, infusion of residual stresses, microstructural evolution, and phase transformations were attempted to enhance the wear resistance of the alloy. The need lies to establish a bridge between the indigenous material properties and the tribo-characteristics of Ti6 Al4 V so that the enforced improvement techniques can raise the barriers of its applicability. A critical review of the microstructural transitions, mechanisms governing tribo-behavior and the parametric conditions leading to material removal at dry sliding conditions of Ti6 Al4 V, falls under the scope of this manuscript. Hence, the prime focus of the approach is to impart a clear-cut perception of the minute variations in mechanical, metallurgical, and tribological characteristics of the alloy at interactive instances with distinct counter-body surfaces. | Jibin T PHILIP Jose MATHEW Basil KURIACHEN | 2019 | Friction2019，7，6： | 10 |
| 2 | Hematological disorders and pulmonary hypertension显示文摘Pulmonary hypertension(PH),a serious disorder with a high morbidity and mortality rate,is known to occur in a number of unrelated systemic diseases.Several hematological disorders such as sickle cell disease,thalassemia and myeloproliferative diseases develop PH which worsens the prognosis.Associated oxidant injury and vascular inflammation cause endothelial damage and dysfunction.Pulmonary vascular endothelial damage/dysfunction is an early event in PH resulting in the loss of vascular reactivity,activation of proliferative and antiapoptotic pathways leading to vascular remodeling,elevated pulmonary artery pressure,right ventricular hypertrophy and premature death.Hemolysis observed in hematological disorders leads to free hemoglobin which rapidly scavenges nitric oxide(NO),limiting its bioavailability,and leading to endothelial dysfunction.In addition,hemolysis releases arginase into the circulation which converts L-arginine to ornithine,thus bypassing NO production.Furthermore,treatments for hematological disorders such as immunosuppressive therapy,splenectomy,bone marrow transplantation,and radiation have been shown to contribute to the development of PH.Recent studies have shown deregulated iron homeostasis in patients with cardiopulmonary diseases including pulmonary arterial hypertension(PAH).Several studies have reported low iron levels in patients with idiopathic PAH,and iron deficiency is an important risk factor.This article reviews PH associated with hematological disorders and its mechanism:and iron homeostasis and its relevance to PH. | Rajamma Mathew Jing Huang Joseph M Wu John T Fallon Michael H Gewitz | 2016 | World Journal of Cardiology2016，8，12： | 6 |
| 3 | Saliva as a non-invasive diagnostic tool for inflammation and insulin-resistance显示文摘Saliva has been progressively studied as a non-invasive and relatively stress-free diagnostic alternative to blood. Currently, saliva testing is used for clinical assessment of hormonal perturbations, detection of HIV antibodies, DNA analysis, alcohol screening, and drug testing. Recently, there has been increasing interest in evaluating the diagnostic potential of saliva in obesity, inflammation, and insulin-resistance. Current literature has demonstrated elevated levels of inflammatory biomarkers including C-reactive protein, tumor necrosis factor-α, interleukin-6, and interferon-γ in saliva of obese/overweight children and adults. Salivary antioxidant status has also been studied as a measure of oxidative stress in individuals with type 2 diabetes. Further, several studies have demonstrated correlations of salivary markers of stress and insulin resistance including cortisol, insulin, adiponectin, and resistin with serum concentrations. These findings suggest the potential diagnostic value of saliva in health screening and risk stratification studies, particularly in the pediatric population, with implications for inflammatory, metabolic and cardiovascular conditions. However, additionalstudies are required to standardize saliva collection and storage procedures, validate analytical techniques for biomarker detection, and establish reference ranges for routine clinical use. The purpose of this review is to summarize and evaluate recent advancements in using saliva as a diagnostic tool for inflammation and insulinresistance. | Gauri S Desai Suresh T Mathews | 2014 | World Journal of Diabetes2014，5，6： | 5 |
| 4 | Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett's esophagus显示文摘AIM To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE,with and without dysplasia,or intramucosal adenocarcinoma (IMC).METHODS This was a retrospective,single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-na?ve or who had persistent intestinal metaplasia(IM),dysplasia,or IMC despite prior therapy.Barrett's mucosa was resected via EMR when clinically appropriate,then patients underwent cryotherapy until eradication or until deemed to have failed treatment.Surveillance biopsies were taken at standard intervals.RESULTS From 2010 through 2014,33 patients were studied regarding the efficacy of cryotherapy.Overall,29 patients (88%) responded to cryotherapy,with 84% having complete regression of all dysplasia and cancer.Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC; the remaining two subjects did not respond to cryotherapy.Following cryotherapy,15 patients with high-grade dysplasia (HGD) had 30% complete regression,50% IM,and 7% low-grade dysplasia (LGD); one subject had persistent HGD.Complete eradication of dysplasia occurred in all 5 patients with LGD.In 5 patients with IM,complete regression occurred in 4,and IM persisted in one.In 136 cryotherapy sessions amongst 45 patients,adverse events included chest pain (1%),stricture (4%),and one gastrointestinal bleed in a patient on dual antiplatelet therapy who had previously undergone EMR.CONCLUSION Cryotherapy is an efficacious and safe treatment modality for Barrett's esophagus with and without dysplasia or intramucosal adenocarcinoma. | Kristen Suchniak-Mussari Charles E Dye Matthew T Moyer Abraham Mathew Thomas J McGarrity Eileen M Gagliardi Jennifer L Maranki John M Levenick | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 4 |
| 5 | Thermomechanical and morphological characteristics of cross-linked GAP and GAP-HTPB networks with different diisocyanates显示文摘 | Suresh Mathew S K Manu T L Varghese | 2008 | Propellants Explosives Pyrotechnics2008，33，2： | 1 |
| 6 | 显示文摘 | Mathews T Manoravi P Antony M P | 2000 | Solid State Ionics2000，135，： | 1 |
| 7 | Parametric study on the combined thermal and hydraulic performance of single phase micro pin-fin heat sinks part I: Square and circle geometries 显示文摘 | JOHN T J MATHEW B HEGAB H | 2010 | International Journal of Thermal Sciences2010，49，11： | 1 |
| 8 | Characterisation of ferulic acid incorporated starch-chitosan blend films显示文摘 | Mathew S Abraham T E | 2008 | Food Hydrocolloids2008，，22： | 1 |
| 9 | Clinicopathological correlates of CD56 expression in multiple myeloma: a unique entity显示文摘 | Mathew P Ahmann G J Witzig T E | 1995 | Br J Haematol1995，90，： | 1 |
| 10 | Intraoperative somatosensory evoked potential findings in acute and chronic spinal canal compromise 显示文摘 | Norcross Nechcoy K Mathew T Simmons JW | 1999 | Spine1999，24，10： | 1 |
| 11 | Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor 显示文摘 | Mathews S T Chellam N Srinivas P R | 2000 | Mol Cell Endocrinol2000，164，12： | 1 |
| 12 | Gasless laparoscopy may reduce the risk of port site metastases following laparascopic tumor surgery显示文摘 | Walson D I Mathew G Ellis T | 1997 | Arch Surg1997，132，2： | 1 |
| 13 | Cu-Co synergism in Cu1-xCoxFe2O4 catalysis and XPS aspects显示文摘 | Mathew T Shiju N R Sreekumar K | 2002 | Journal of Catalysis2002，210，： | 1 |
| 14 | Robust trans- portation network design under demand uncertainty显示文摘 | Ukkusui S V Mathew T V Wailer S T | 2007 | Computer-Aided Civil and Infrastructure Engi- neering2007，22，1： | 1 |
| 15 | Characterisation of ferulic acid incorporated starch-chitosan blend films显示文摘 | Mathew S Abraham T E | 2008 | Food Hydrocolloids2008，22，5： | 1 |
| 16 | Palladium catalyzed Suzuki cross-coupling reactions in ambient temperature ionic liquids显示文摘 | MATHEWS C J SMITH P J WELTON T | 2000 | Chemical Communications2000，14，： | 1 |
| 17 | Relationship between assays of inflammation and coagulation:A novel interpretation of the canine acti- vated clotting time显示文摘 | CHENG T MATHEWS K A ABRAMS-OGG A C | 2009 | Can J Vet Res2009，73，： | 1 |
| 18 | Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene 显示文摘 | Mathews S T Singh G P Ranalletta M | 2002 | Diabetes2002，51，8： | 1 |
| 19 | Factors influencing the careseeking behaviour of chest symptomatics: a community-based study involving rural and urban population in Tamil Nadu, South India 显示文摘 | Sudha G Nirupa C Rajasakthivel M Sivasusbramanian S Sundaram V Bhatt S Subramaniam K Thiruvalluvan E Mathew R Renu G Santhal T | 2003 | Tropical Medicine and International Health2003，8，4： | 1 |
| 20 | The phytochrome apoprotein family in Arabidopsisis encoded by five genes:the sequences and expression of PHYD and PHYE显示文摘 | Clack T Mathews S Sharrock R A | 1994 | Plant Mol Biol1994，25，： | 1 |
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