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59篇 您的检索式:作者名="Mathee"
    题名 作者 年代 出处 被引量
1含新的mucA突变基因黏液型铜绿假单胞菌生物被膜特性的研究显示文摘目的研究含新的mucA突变基因黏液型铜绿假单胞菌(PAE17)在不同条件下形成的生物被膜,以了解新的mucA突变基因对铜绿假单胞菌生物被膜的影响。方法采用PIA平板法鉴定3种铜绿假单胞菌的黏液表型,色氨酸反应法测定其胞外多糖蛋白复合物的合成量;刚果红染色法和静态培养法分别观察其在固态及液态条件下形成的生物被膜;采用电转化法将绿色荧光蛋白表达质粒(pGFPuv)导入上述3种病原菌中,应用改良平板法建立体外生物被膜模型,激光共聚焦显微镜观察不同时间点生物被膜的形成。结果PAE17与PDO300呈现明显的黏液表型,其胞外多糖的产量(101.6μg/ml、118.3μg/ml)显著高于PAEO1(56.3μg/ml),但无论在固态、液态和改良平板法体外生物被膜模型中,PAE17形成的生物被膜均与PDO300迥异,而表现类似PAEO1。结论新的mucA突变基因可能存在藻酸盐以外的其他途径调节生物被膜的形成。陈安群 田德英 宋世会 吴会玲 倪明 Kalai Mathee 2008中华医院感染学杂志2008,18,9:4
2卡介苗预先免疫对大鼠慢性绿脓杆菌性肺炎的影响显示文摘为了探讨卡介苗 (BCG )预先免疫对大鼠慢性绿脓杆菌 (PA )性肺炎模型的影响。采用BCG或灭菌生理盐水皮内注射预先免疫 3周 ,然后由支气管内予以PA攻击 ;2周后评估各组的肺部细菌学、肺组织病理学、肺部细胞因子 (IL 4、IFN γ、TNF α )反应、血清PA特异性抗体IgG水平的变化。结果显示BCG免疫组肺组织内的IFN γ、TNF α水平显著升高 (P <0 0 5 ) ,肺组织匀浆PA菌落计数明显低于生理盐水对照组 (P <0 0 1) ;肺组织病理改变及血清PA特异性抗体IgG水平两组均无显著差异 (P >0 0 5 )。以上结果提示BCG接种能够诱导肺部Th1型免疫反应 ,加快PA性肺炎大鼠肺部的细菌清除 。郭向华 宋志军 吴红 闫萍 覃雪君 Kalai Mathee Niels Hoiby 唐步坚 仇晓强 陈一强 2004现代免疫学2004,24,2:4
3Anti-quorum sensing activity of medicinal plants in southern Florida显示文摘Allison L. Adonizio Kelsey Downum Bradley C. Bennett Kalai Mathee 2005Journal of Ethnopharmacology2005,,3:2
4Appendix tumors in the era of laparoscopic appendectomy显示文摘P. Bucher Z. Mathe A. Demirag Ph. Morel 2004Surgical Endoscopy2004,,7:2
5A survey of blood lead levels among young Johannesburg school children显示文摘Mathee A Schirnding YER Levin J 2002The Science of the Total Environment2002,90,3:1
6Morbidity associated with intraportal islet transplantation显示文摘Bucher P Mathe Z Bosco D 0,,04:1
7Proteome analysis of the effect of mucoid conversion on global protein expression in Pseudomonas aeruginosa strain PAO1 shows induction of the disulfide bond isomerase, DsbA显示文摘Malhotra S Silo-Suh LA Mathee K 2000J Bacteriol2000,182,:1
8查看详情显示文摘Fawzi A.S Sheikh A.D Mathe V.L 0,,01:1
9Characterization of archaeological frankincense by gas chromatography–mass spectrometry显示文摘Carole Mathe Gérald Culioli Paul Archier Cathy Vieillescazes 2003Journal of Chromatography A2003,,2:1
10Estimating the burden of disease attributable to lead exposure in South Africa in 2000显示文摘Norman R Mathee A Barnes B 2007S Afr Med J2007,97,:1
11Inhibition of quorum sensing- controlled virulence factor production in Pseudomonas aeruginosa by South Florida plant extract显示文摘ADONIZIO A KONG K F MATHEE K 2008Antimicrobial Agents and Chemotherapy2008,52,:1
12Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung 显示文摘MATHEE K CIOFU O STERNBERG C 1999Microbiology1999,145,6:1
13Paraganglioma of the ampulla of vater: a potentially malignant neoplasm显示文摘P. Bucher Z. Mathe L. Bühler M. Chilcott P. Gervaz J.‐F. Egger Ph. Morel 2004Scandinavian Journal of Gastroenterology2004,,3:1
14MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus:associations with survival显示文摘Mathe EA Nguyen GH Bowman ED 0,,:1
15Beta-lactam antibiotics: from antibiosis to resistance and bacteriology显示文摘Kong KF Schneper L Mathee K 2010APMS2010,118,1:1
16BDNF in schizophrenia,depression and corresponding animal models显示文摘Angelucci F Brene S Mathe AA 0,,04:1
17MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus:associations with survival显示文摘Mathe EA Nguyen GH Bowman ED 0,,19:1
18Beta-lactam antibiotics:from antibiosis to resistance and bacteriology显示文摘Kong KF Schneper L Mathee K 2010APMIS2010,118,1:1
19Inhibition of the ras-dependent mitogenic pathway by phosphopeptide prodrugs with antiproliferative properties显示文摘Liu WQ Vidal M Mathe C 0,,07:1
20Inhibition of quorum sensing- controlled virulence factor production in Pseudomonas aeruginosa by South Florida plant extract 显示文摘Allison Adonizio Kok- Fai Kong Kalai Mathee 2008Antimicrobial agents and chemotherapy2008,52,1:1
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