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    题名 作者 年代 出处 被引量
1The genetics of tiger pelage color variations显示文摘Xiao XU Gui-Xin Dong Anne Schmidt-Kuntzel Xue-Li Zhang Yan Zhuang Run Fang Xin Sun Xue-Song Hu Tian-You Zhang Han-Dong Yang De-Lu Zhang Laurie Marker Zheng-Fan Jiang Ruiqiang Li Shu-Jin Luo 2017Cell Research2017,27,7:5
2Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients.Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton 2008World Journal of Gastroenterology2008,14,3:4
3Individualized home-monitoring of disease activity in adult patients with inflammatory bowel disease can be recommended in clinical practice: A randomized-clinical trial显示文摘BACKGROUND The optimal way to home-monitor patients with inflammatory bowel disease(IBD)for disease progression or relapse remains to be found.AIM To determine whether an electronic health(eHealth)screening procedure for disease activity in IBD should be implemented in clinical practice,scheduled every third month(3M)or according to patient own decision,on demand(OD).METHODS Adult IBD patients were consecutively randomized to 1-year open-label eHealth interventions(3M vs OD).Both intervention arms were screening for disease activity,quality of life and fatigue and were measuring medical compliance with the constant care web-application according to the screening interventions OD or 3M.Disease activity was assessed using home measured fecal calprotectin(FC)and a disease activity score.RESULTS In total,102 patients were randomized(n=52/503M/OD)at baseline,and 88 patients completed the 1-year study(n=433M;n=45 OD).No difference in the two screening procedures could be found regarding medical compliance(P=0.58),fatigue(P=0.86),quality of life(P=0.17),mean time spent in remission(P>0.32),overall FC relapse rates(P=0.49),FC disease courses(P=0.61),FC time to a severe relapse(P=0.69)and remission(P=0.88)during 1 year.Median(interquartile range)numbers of FC home-monitoring test-kits used per patient were significantly different,3M:6.0(5.0-8.0)and OD:4.0(2.0-9.0),P=0.04.CONCLUSION The two eHealth screening procedures are equally good in capturing a relapse and bringing about remission.However,the OD group used fewer FC home testkits per patient.Individualized screening procedures can be recommended for adult IBD patients in clinical web-practice.Dorit Vedel Ankersen Petra Weimers Dorte Marker Mette Bennedsen Sanaz Saboori Kristine Paridaens Johan Burisch Pia Munkholm 2019World Journal of Gastroenterology2019,25,40:2
4Results of Total Knee Replacement for Isolated Patellofemoral Arthritis: When Not to Perform a Patellofemoral Arthroplasty显示文摘Ronald E. Delanois Mike S. McGrath Slif D. Ulrich David R. Marker Thorsten M. Seyler Peter M. Bonutti Michael A. Mont 2008Orthopedic Clinics of North America2008,,3:2
5Essential diagnostic tools for radiologists显示文摘 2003Nippon Hoshasen Gakkai Zasshi2003,63,4:1
6Reciprocal mouse and human limb phenotypes caused by gainand loss-of-function mutations affecting lmbr1显示文摘Clark R M Marker P C Roessler E 2001Genetics2001,159,2:1
7syndromes显示文摘Quilici j Banzet N Paule P Circulating endothelial cell count as a diagnostic marker for non-ST-elevation acute coronary 2004Circulation2004,110,10:1
8The natural history of un- treated asymptomatic osteonecrosis of the femoral head : a system- atic literature review 显示文摘Mont MA Zywiel MG Marker DR 2010J Bone jroint Surg Am2010,92,12:1
9BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice显示文摘King J A Marker P C Seung K J 1994Dev Biol1994,166,1:1
10Application to clinical and public health practice:a statement for health care professionals from the centers for disease control and prevention and American heart association显示文摘Person TA Mensah GA Alexander RW Markers of inflammation and cardiovascular disease 2003Circulation2003,107,3:1
11BMP5 and the molecular,skeletal,and soft-tissue alterations in short ear mice显示文摘King JA Marker PC Seung KJ 0,,01:1
12Alveolar soft-part sarcoma of the oral cavity: report of a case and review of the literature 显示文摘Marker P Jensen ML Siemssen SJ 1995J Oral Maxillofac Surg1995,53,10:1
13Postoperative hemodynamic and thermoregulatory conseguences of intraoperative core hypothmia 显示文摘Kurz A Sessler DI Marker E 1995J Clin Anesth1995,7,:1
14Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation,apoptosis,and cell attachment显示文摘Woodworth CD Michael E Marker D 2005Mol Cancer Ther2005,4,4:1
15Multiple immuno-regulatory defects in type-1 diabetes 显示文摘Kukreja A Cost G Marker J 2002J Clin Invest2002,109,1:1
16BMP5 and the molecular,skeletal,and soft-tissue alterations in short ear mice显示文摘KINGSLEY D M KING J A MARKER P C 1994Dev Biol1994,166,:1
17Knee Arthroplasties Have Similar Results in High- and Low-activity Patients显示文摘Mont MA Marker DR Seyler TM 2007Clin Orthop2007,460,:1
18Resuscitation from Severe hemorrhage显示文摘Willian C Shoe Marker Anderew.B 0,,2:1
19The natural history of untreated asymptomatic osteonecrosis of the femoral head:a systematic literature review显示文摘Mont MA Zywiel MG Marker DR 2010J Bone Joint Surg Am2010,92,12:1
20BMP5and the molecular,skeletal,and soft-tissue alterations in short ear mice显示文摘KING J A MARKER P C SEUNG K J 1994Dev Biol1994,166,:1
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