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| 1 | Global blue carbon accumulation in tidal wetlands increases with climate change显示文摘Coastal tidal wetlands produce and accumulate significant amounts of organic carbon(C)that help to mitigate climate change.However,previous data limitations have prevented a robust evaluation of the global rates and mechanisms driving C accumulation.Here,we go beyond recent soil C stock estimates to reveal global tidal wetland C accumulation and predict changes under relative sea level rise,temperature and precipitation.We use data from literature study sites and our new observations spanning wide latitudinal gradients and 20 countries.Globally,tidal wetlands accumulate 53.65(95%CI:48.52-59.01)Tg C yr^(-1),which is~30%of the organic C buried on the ocean floor.Modeling based on current climatic drivers and under projected emissions scenarios revealed a net increase in the global C accumulation by2100.This rapid increase is driven by sea level rise in tidal marshes,and higher temperature and precipitation in mangroves.Countries with large areas of coastal wetlands,like Indonesia and Mexico,are more susceptible to tidal wetland C losses under climate change,while regions such as Australia,Brazil,the USA and China will experience a significant C accumulation increase under all projected scenarios. | Faming Wang Christian J.Sanders Isaac R.Santos Jianwu Tang Mark Schuerch Matthew L.Kirwan Robert E.Kopp Kai Zhu Xiuzhen Li Jiacan Yuan Wenzhi Liu Zhian Li | 2021 | National Science Review2021，8，9： | 22 |
| 2 | Effects of elevation on spring phenological sensitivity to temperature in Tibetan Plateau grasslands显示文摘Vegetation phenology is an important indicator of climate change impacts on the seasonal dynamics of the biosphere. However, little is known about the influence of elevation on spring phenological sensitivity to temperature in an alpine ecosystem. Based on remotely sensed land surface phenology and temperature data from 2001 to2010, this study investigated the rate of spring phenological change of the Tibetan Plateau(TP) grasslands in response to interannual temperature variations at different elevations. Results suggest that spring phenology in the TP grasslands exhibits a stronger response to changes in temperature at higher elevations than at lower ones. In particular, spring phenology advanced by 1–2 days in response to a 1 °C increase in May average temperature at elevations from 3,000 to 3,500 m, while the rate was up to8–9 days/°C at 5,000–5,500 m. Analysis using accumulated growing degree days(AGDD) from January 1through May 31 showed the same general trend with increased elevation associated with increased sensitivity(as measured by phenological change per unit of AGDDchange). Such temperature sensitivity gradients in the TP grasslands could be partly explained by the growth efficiency hypothesis which suggests that vegetation adapted to colder climates likely requires less heat energy for the onset of growing season and vice versa in warmer climates.Furthermore, accumulated growing degree days from January 1 to the greenup date were found to decrease with increasing elevations, which provided evidence to support the applicability of the growth efficiency hypothesis in an alpine grassland ecosystem. | Lingling Liu Liangyun Liu Liang Liang Alison Donnelly Isaac Park Mark D.Schwartz | 2014 | Chinese Science Bulletin2014，59，34： | 7 |
| 3 | Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding显示文摘AIM: To determine the frequency of small bowel ulcerative lesions in patients with peptic ulcer and define the significance of those lesions. METHODS: In our prospective study, 60 consecutive elderly patients with upper gastrointestinal bleeding from a peptic ulceration(cases) and 60 matched patients with a non-bleeding peptic ulcer(controls) underwent small bowel capsule endoscopy, after a negative colonoscopy(compulsory in our institution). Controls were evaluated for non-bleeding indications. Known or suspected chronic inflammatory conditions and medication that could harm the gut were excluded. During capsule endoscopy, small bowel ulcerative lesions were counted thoroughly and classified according to Graham classification. Other small bowellesions were also recorded. Peptic ulcer bleeding was controlled endoscopically, when adequate, proton pump inhibitors were started in both cases and controls, and Helicobacter pylori eradicated whenever present. Both cases and controls were followed up for a year. In case of bleeding recurrence upper gastrointestinal endoscopy was repeated and whenever it remained unexplained it was followed by repeat colonoscopy and capsule endoscopy.RESULTS: Forty(67%) cases and 18(30%) controls presented small bowel erosions(P = 0.0001), while 22(37%) cases and 4(8%) controls presented small bowel ulcers(P < 0.0001). Among non-steroidal antiinflammatory drug(NSAID) consumers, 39(95%) cases and 17(33%) controls presented small bowel erosions(P < 0.0001), while 22(55%) cases and 4(10%) controls presented small bowel ulcers(P < 0.0001). Small bowel ulcerative lesions were infrequent among patients not consuming NSAIDs. Mean entry hemoglobin was 9.3(SD = 1.4) g/d L in cases with small bowel ulcerative lesions and 10.5(SD = 1.3) g/dL in those without(P = 0.002). Cases with small bowel ulcers necessitate more units of packed red blood cells. During their hospitalization, 6(27%) cases with small bowel ulcers presented bleeding recurrence most possibly attributed to small bowel ulcers, nevertheless 30-d mortality was zero. Presence of chronic obstructive lung disease and diabetes was related with unexplained recurrence of hemorrhage in logistic regression analysis, while absence of small bowel ulcers was protective(relative risk 0.13, P = 0.05).CONCLUSION: Among NSAID consumers, more bleeders than non-bleeders with peptic ulcers present small bowel ulcers; lesions related to more severe bleeding and unexplained episodes of bleeding recurrence. | Panagiotis Tsibouris Chissostomos Kalantzis Periklis Apostolopoulos Antonios Zalonis Peter Edward Thomas Isaacs Mark Hendrickse Georgios Alexandrakis | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，12： | 6 |
| 4 | Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention显示文摘AIM:To assess pediatric patients for choledocholithiasis.We applied current adult guidelines to identify predictivefactors in children.METHODS:A single-center retrospective analysis was performed at a tertiary children's hospital.We evaluated 44 consecutive pediatric patients who underwent endoscopic retrograde cholangiography(ERCP) for suspected choledocholithiasis.Patients were stratified into those with common bile duct stones(CBDS) at ERCP vs those that did not using the American Society of Gastrointestinal Endoscopy(ASGE) guidelines(Very Strong and Strong criteria) for suspected CBDS.RESULTS:CBDS were identified in 84% at the time of ERCP.Abdominal ultrasound identified CBDS in 36% of patients.Conjugated bilirubin ≥ 0.5 mg/d L was an independent risk factor for CBDS(P = 0.003).The Very Strong(59.5%) and Strong(48.6%) ASGE criteria identified the majority of patients(P = 0.0001).A modified score using conjugated bilirubin had a higher sensitivity(81.2% vs 59.5%) and more likely to identify a stone than the standard criteria,odds ratio of 25.7 compared to 8.8.Alanine aminotransferase and gamma-glutamyl transferase values identified significant differences in a subset of patients with odds ratio of 4.1 and 3.25,respectively.CONCLUSION:Current adult guidelines identified the majority of pediatric patients with CBDS,but specific pediatric guidelines may improve detection,thus decreasing risks and unnecessary procedures. | Douglas S Fishman Bruno P Chumpitazi Isaac Raijman Cynthia Man-Wai Tsai E O’Brian Smith Mark V Mazziotti Mark A Gilger | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，11： | 6 |
| 5 | A multi‐institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer显示文摘 | Edward J. Kim Edgar Ben‐Josef Joseph M. Herman Tanios Bekaii‐Saab Laura A. Dawson Kent A. Griffith Isaac R. Francis Joel K. Greenson Diane M. Simeone Theodore S. Lawrence Daniel Laheru Christopher L. Wolfgang Terence Williams Mark Bloomston Malcolm J. Moo | 2013 | Cancer2013，，15： | 3 |
| 6 | Bio-inspired carbon electro-catalysts for the oxygen reduction reaction显示文摘We report the synthesis, characterisation and catalytic performance of two nature-inspired biomassderived electro-catalysts for the oxygen reduction reaction in fuel cells. The catalysts were prepared via pyrolysis of a real food waste(lobster shells) or by mimicking the composition of lobster shells using chitin and CaCO_3 particles followed by acid washing. The simplified model of artificial lobster was prepared for better reproducibility. The calcium carbonate in both samples acts as a pore agent, creating increased surface area and pore volume, though considerably higher in artificial lobster samples due to the better homogeneity of the components. Various characterisation techniques revealed the presence of a considerable amount of hydroxyapatite left in the real lobster samples after acid washing and a low content of carbon(23%), nitrogen and sulphur(<1%), limiting the surface area to 23 m^2/g, and consequently resulting in rather poor catalytic activity. However, artificial lobster samples, with a surface area of ≈200 m^2/g and a nitrogen doping of 2%, showed a promising onset potential, very similar to a commercially available platinum catalyst, with better methanol tolerance, though with lower stability in long time testing over 10,000 s. | Kathrin Preuss Vasanth Kumar Kannuchamy Adam Marinovic Mark Isaacs Karen Wilson Isaac Abrahams Maria-Magdalena Titirici | 2016 | Journal of Energy Chemistry2016，25，2： | 3 |
| 7 | Absolute and Relative Rewards for Individuals in Team Production 显示文摘 | Dickinson David L Isaac Mark R | 1998 | Manageri- al and Decision Economics1998，19，45： | 1 |
| 8 | In search of predatory pricing 显示文摘 | Isaac R Mark and Vernon L Smith | 1985 | Journal of Political Economy1985，93，： | 1 |
| 9 | An instrument for assessing imagery of movement: the vividness of move ment imagery questionnaire 显示文摘 | Isaac A Mark D F Russell D G | 1986 | Journal of mental im agery1986，10，4： | 1 |
| 10 | Endovenous Laser Treatment of the Incompetent Greater Saphenous Vein显示文摘 | Robert J. Min Steven E. Zimmet Mark N. Isaacs Mark D. Forrestal | 2001 | Journal of Vascular and Interventional Radiology2001，，10： | 1 |
| 11 | Market contestability in the presence ot sunk costs 显示文摘 | Coursey Don R Mark Isaac Margaret luke and Veron I Smith | 1984 | Rand Journal of Economics1984，15，： | 1 |
| 12 | An instrument for assessing imagery of movement: the vividness of movement imagery questionnaire (VMIQ) 显示文摘 | Isaac A Marks DF Russell DG | 1986 | Journal of Mental Imagery1986，10，： | 1 |
| 13 | A Practical Archi-tecture for Reliable Quantum Computers显示文摘 | Frederic T C Isaac C | 2002 | IEEE Computer2002，1，： | 1 |
| 14 | Long-term herbarium records reveal temperature-dependent changes in flower- ing phenology in the southeastern USA显示文摘 | Isaac W Park Mark D Schwartz | 2015 | International Journal of Biometeorology2015，59，3： | 1 |
| 15 | Uterine atery embolization versusmyomectomy:impact on quality of life-results of the FUME(fibroidsuterus:myomectomy versus embolization)trial显示文摘 | Isaac TM Mark B Jessica SH | 2011 | Cardiovasc Inter-vent Radiol2011，27，7： | 1 |
| 16 | Individual differences in mental imagery experi- ence: developmental changes and specialization 显示文摘 | Isaac AR Marks DF | 1994 | Br J Psychol1994，85，4： | 1 |
| 17 | The Spectrum and Natural History of Common Bile Duct Stenosis in Chronic Alcohol-Induced Pancreatitis显示文摘 | ISAAC KALVARIA PHILLIP C. BORNMAN I. N. MARKS ANDREW H. GIRDWOOD LESLIE BANK RONALD E. KOTTLER | 1989 | Annals of Surgery1989，，5： | 1 |
| 18 | Sensitivity Analysis of a Tightly-Coupled GPC/INS System for autonomous Navigation显示文摘 | Isaac Miller Mark Campbell | 2012 | IEEE Transactions on Aerospace and Electronic Systems2012，，48： | 1 |
| 19 | Topographical distribution of EEG activity accompanying visual and motor imagery in vivid and non-vivid imagers显示文摘 | Marks DF Isaac AR | 1995 | Brit J Psycho11995，86，： | 1 |
| 20 | An instrument for assessing imagery of movement:the vividness of movement imagery questionnaire (VMIQ)显示文摘 | ISAAC A MARKS D F RUSSELL D G | 1986 | Ment Imagery1986，10，： | 1 |
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