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| 1 | Device-associated infection rates, mortality, length of stay and bacterial resistance in intensive care units in Ecuador: International Nosocomial Infection Control Consortium's findings显示文摘AIM To report the results of the International Nosocomial Infection Control Consortium(INICC) study conducted in Quito, Ecuador.METHODS A device-associated healthcare-acquired infection(DAHAI) prospective surveillance study conducted from October 2013 to January 2015 in 2 adult intensive care units(ICUs) from 2 hospitals using the United States Centers for Disease Control/National Healthcare Safety Network(CDC/NHSN) definitions and INICC methods. RESULTS We followed 776 ICU patients for 4818 bed-days. The central line-associated bloodstream infection(CLABSI) rate was 6.5 per 1000 central line(CL)-days, the ventilator-associated pneumonia(VAP) rate was 44.3 per 1000 mechanical ventilator(MV)-days, and the catheterassociated urinary tract infection(CAUTI) rate was 5.7 per 1000 urinary catheter(UC)-days. CLABSI and CAUTI rates in our ICUs were similar to INICC rates [4.9(CLABSI) and 5.3(CAUTI)] and higher than NHSN rates [0.8(CLABSI) and 1.3(CAUTI)]- although device use ratios for CL and UC were higher than INICC and CDC/NSHN's ratios. By contrast, despite the VAP rate was higher than INICC(16.5) and NHSN's rates(1.1), MV DUR was lower in our ICUs. Resistance of A. baumannii to imipenem and meropenem was 75.0%, and of Pseudomonas aeruginosa to ciprofloxacin and piperacillin-tazobactam was higher than 72.7%, all them higher than CDC/NHSN rates. Excess length of stay was 7.4 d for patients with CLABSI, 4.8 for patients with VAP and 9.2 for patients CAUTI. Excess crude mortality in ICUs was 30.9% for CLABSI, 14.5% for VAP and 17.6% for CAUTI. CONCLUSION DA-HAI rates in our ICUs from Ecuador are higher than United States CDC/NSHN rates and similar to INICC international rates. | Estuardo Salgado Yepez Maria M Bovera Victor D Rosenthal Hugo A González Flores Leonardo Pazmino Francisco Valencia Nelly Alquinga Vanessa Ramirez Edgar Jara Miguel Lascano Veronica Delgado Cristian Cevallos Gasdali Santacruz Cristian Pelaéz Celso Zaruma Diego Barahona Pinto | 2017 | World Journal of Biological Chemistry2017，8，1： | 23 |
| 2 | Effects of exogenous enzymes, Lactobacillus acidophilus or their combination on feed performance response and carcass characteristics of rabbits fed sugarcane bagasse显示文摘The aim of this study was to evaluate the effect of Lactobacillus acidophilus(LAC), exogenous enzymes of ZAD(exogenous enzyme preparation) or their combination on feed conversion, and dressing of rabbits fed different treatments of sugarcane bagasse(SCB). Five rations were allotted randomly to five groups of New-Zealand White(NZW) rabbits(n=10) with initial live body weight of(838±42.4) g and 5 weeks of age. Rabbits were fed on diets with different sources of fiber as follows,(i) a control diet composed of 100% berseem hay and 0% SCB,(ii) 50% berseem hay and 50% untreated SCB(USCB),(iii) 50% berseem hay and 50% SCB treated with L. acidophilus(LAC),(iv) 50% berseem hay and 50% SCB treated with ZAD(ZAD), and(v) 50% berseem hay and 50% SCB treated with a combination of LAC+ZAD(LZ). Treatments of SCB with L. acidophilus, ZAD and LAC+ZAD had the highest feed conversion ratio than both USCB and control. The dressing percentage of rabbits that fed the LAC and LZ diets was higher(P<0.05) compared with that in the other groups. Performance index(PI) for LAC group was improved(P<0.05) compared to that for the other groups; however, PI for USCB group was the lowest(P<0.05). It could be concluded that treating SCB with L. acidophilus, exogenous enzymes of ZAD or their combination improved feed conversion and performance with more positive effects with L. acidophilus than the other treatments. | Nahla A Abdel-Aziz Mounir El-Adawy Maria A Mariezcurrena-Berasain Abdelfattah Z M Salem Jaime Olivares-Pérez Ahmed E Kholif Borhami E Borhami | 2015 | Journal of Integrative Agriculture2015，14，3： | 5 |
| 3 | Constant serum levels of secreted asialoglycoprotein receptor sH2a and decrease with cirrhosis显示文摘AIM: To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS: Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentration of sH2a in human sera of individuals of both sexes and a wide range of ages. RESULTS: The recombinant protein was produced successfully and a specific ELISA assay was developed. The levels of sH2a in sera from 62 healthy individuals variedminimally (147 ± 19 ng/mL). In contrast, 5 hepatitis C patients with cirrhosis showed much decreased sH2a levels (50 ± 9 ng/mL). CONCLUSION: Constant sH2a levels suggest constitutive secretion from hepatocytes in healthy individuals. This constant level and the decrease with cirrhosis suggest a diagnostic potential. | Ron Benyair Maria Kondratyev Elena Veselkin Sandra Tol-chinsky Marina Shenkman Yoav Lurie Gerardo Z Lederkremer | 2011 | World Journal of Gastroenterology2011，17，48： | 3 |
| 4 | Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia,Canada显示文摘AIM To describe the characteristics of people diagnosed with acute and chronic hepatitis B virus(HBV) infection in British Columbia(BC).METHODS We used data from the BC Hepatitis Testers Cohort(BCHTC),which includes all individuals tested for hepatitis C virus(HCV) or human immunodeficiency virus(HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990.These data were integrated with prescription drug,medical visit,hospitalization and mortality data.HBV cases were classified as acute or chronic according to provincial guidelines.We compared characteristics of individuals by HBV infection group(acute,chronic and negative).Factors associated with acute or chronic HBV infection were assessed with multinomial logistic regression models in comparison to the HBV negative group.RESULTS46498 of the 1058056 eligible BC-HTC participants were diagnosed with HBV infection.4.3% of HBV positive individuals were diagnosed with acute HBV infections while 95.7% had chronic infections.Problematic alcohol use,injection drug use,and HIV or HCV co-infection were more common among individuals diagnosed with acute HBV compared to those with chronic infections and HBV negative individuals.In multivariable multinomial logistic regression models,we observed significant associations between acute or chronic HBV diagnosis and being male,age at HBV diagnosis or birth cohort,South and East Asian ethnicity,HCV or HIV infection,and injection drug use.The odds of acute HBV decreased with increasing age among people who inject drugs,while the opposite was true for chronic HBV.Persons with acute HBV were predominantly White(78%) while those with chronic HBV were mostly East Asian(60%).Relative to Whites,East Asians had 12 times greater odds of being diagnosed with chronic HBV infection.These odds increased with increasing socioeconomic deprivation.CONCLUSION Differences in the profiles of people diagnosed with acute and chronic HBV infection necessitate differentiated screening,prevention,care and treatment programs. | Mawuena Binka Zahid A Butt Stanley Wong Mei Chong Jane A Buxton Nuria Chapinal Amanda Yu Maria Alvarez Maryam Darvishian Jason Wong Gina McGowan Mikhail Torban Mark Gilbert Mark Tyndall Mel Krajden Naveed Z Janjua | 2018 | World Journal of Gastroenterology2018，24，11： | 3 |
| 5 | Indoleamine 2,3-dioxygenase (IDO) expression in lung cancer 显示文摘 | Vaios K Maria Z Theodora K et ol | 2007 | Cancer Biology & Therapy2007，6，8： | 1 |
| 6 | Restrictions to the adaptation of influenza A virus H5 hemaggluti-nin to the human host显示文摘 | Andrew C R M Maria Z | 2004 | J Virol2004，78，： | 1 |
| 7 | Involvement of the pancreas in AIDS: a prospective study of 109 post-mortems显示文摘 | Ethel Z Chehter Maria Antonieta Longo Antonio A Laudanna Maria Irma S Duarte | 2000 | AIDS2000，，13： | 1 |
| 8 | Combined pcr-heteroduplex mobility assay for detection and differentiation of influenza A viruses from different animal species显示文摘 | Joanna S E Maria Z | 2001 | Journal of Clinical Microbiology2001，39，11： | 1 |
| 9 | Looking through the qualities of a fluorimetric assay for the total phenol content estimation in virgin olive oil,olive fruit or leaf polar extract显示文摘 | VASSILIKI T P MARIA Z T | 2009 | Food Chemistry2009，112，1： | 1 |
| 10 | Escherichia coli AspP activity is enhanced by macromolecular crowding and by both glucose-1, 6-bisphosphate and nucleotide-sugars 显示文摘 | Maria T M Z Alejandro M V Francisco J M | 2007 | FEBS Lett2007，581，5： | 1 |
| 11 | Catalytic ozonation and methods of enhancing molecular ozone reactions in water treatment显示文摘 | HORDERN B K MARIA Z NAWROCKI J | 2003 | Applied Catalysis B:Environmental2003，46，： | 1 |
| 12 | Silicone-containing polymer matrices as protective coatings properties and applications 显示文摘 | Maria Z Elibieta B | 2006 | Prog Org Coat2006，55，161： | 1 |
| 13 | Fluence-to-dose conversion coefficients for neu- trons and protons calculated using the PHITS code and ICRP/ICRU adult reference computa- tional phantoms显示文摘 | TATSUHIKO S AKIRA E MARIA Z | 2009 | Physics in Medicine and Bi- ology2009，54，7： | 1 |
| 14 | Differential MMP and TIMP production by human marrow and peripheral blood CD34 + cells in response to chemokines显示文摘 | Anna Janowska-Wieczorek Leah A Marquez Adrian Dobrowsky Mariusz Z Ratajczak Maria Luisa Cabuhat | 2000 | Experimental Hematology2000，，11： | 1 |
| 15 | Isolation and some properties of collagen from the backbone of baltic cod (Gadus morhua) 显示文摘 | ELZBIETA Z MARIA S MAGDALENA T | 2010 | Food Hydrocolloids2010，24，4： | 1 |
| 16 | Evolution of octopod sperm Ⅰ:Comparison of nuclear morphogenesis in Eledone and Octopus显示文摘 | PEPITA G B ENRIC R MARIA J Z | | 0，，62： | 1 |
| 17 | Catalytic ozonation and methods of enhanceing molecular ozone reactions in water treatment 显示文摘 | Barbara K H Maria Z Jacek N | 2003 | Appl Catal B:Environ2003，46，： | 1 |
| 18 | Survivin expression and resistance to anticancer treatments:perspectives for new therapeutic interventions显示文摘 | Nadia Z Maria GD | 2002 | Drug Resistance Updates2002，5，2： | 1 |
| 19 | Kinetic parameters determination in non-isothermal conditions for the crystal- lisation of a silic-soda-lead glass显示文摘 | OANA C M MARIA Z GEORGETA J | 2006 | J Thermal and Calorimetry2006，86，2： | 1 |
| 20 | Carbon nanofibor reinforced cement - based materials 显示文摘 | Metaxa Z S Konsta C doutos Maria S Shah Surendra P | 2010 | Transportation Research Board2010，，2142： | 1 |
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