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1420篇 您的检索式:作者名="Man H"
    题名 作者 年代 出处 被引量
1美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病源性轻度认知障碍诊断标准推荐显示文摘美国国立老化研究所(NIA)和阿尔茨海默病协会(ADA)组织了一个工作组,负责阿尔茨海默病(AD)痴呆前症状阶段——即本文所称的AD源性轻度认知障碍(MCI)的诊断标准的制订及完善。该工作组制订了以下两套标准:(1)在缺乏相应条件进行先进影像技术及脑脊液检查时,医务人员适用的核心临床标准;(2)适用于包括临床试验在内的科学研究的研究标准。后者纳入了基于影像技术及脑脊液检查的生物标志物的应用。并根据所出现的生物标志物的性质,将最终MCI诊断的确定性程度分为4个级别。而要使生物标志物有效应用于诊断,并在社区医疗服务中规范使用,尚需做大量的工作。McKhann GM Knopman DS Chertkow H Hyman BT Jack CR Jr Kawas CH Klunk WE Koroshetz WJ Manly JJ Mayeux R Mohs RC Morris JC Rossor MN Schehens P Carrillo MC Thies B Weintraub S Phelps CH 贾建平(译) 陆璐(译) 张逸驰(译) 黄丽黄(译) 礼媛(译) 2012中华神经科杂志2012,45,5:51
2美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病痴呆诊断标准的推荐显示文摘由美国国立老化研究所(NIA)和阿尔茨海默病(AD)协会组织了一个工作组,负责修订1984年版AD痴呆的诊断标准。旨在确保修订后的标准具有足够的灵活性,既可供缺乏神经心理学测验、先进的影像技术和脑脊液检查措施的普通医务人员使用,也可供具备上述措施的科研、临床试验的专业研究者使用。新的标准广泛适用于各种原因的痴呆以及专门针对AD痴呆的标准,保留了1984年版标准中的“很可能的AD痴呆”的总体框架。在过去27年的经验基础上,工作组对临床诊断标准做了一些修改,保留了“可能的AD痴呆”的术语,但对其进行了更有针对性的重新定义。在科研用的“很可能的和可能的AD痴呆”的诊断标准中纳入了生物标志物证据。AD痴呆的核心临床标准仍将是临床实践中诊断的基础,但用生物标志物证据来提高AD痴呆诊断的病理生理学特异性也被人们寄予厚望。要实现AD痴呆的生物标志物诊断,还有许多工作摆在面前。McKhann GM Knopman DS Chertkow H Hyman BT Jack CR Jr Kawas CH Klunk WE Koroshetz WJ Manly J J Mayeux R Mohs RC Morris JC Rossor MN Scheltens P Carrillo MC Thies B Weintraub S Phelps CH 贾建平(译) 陆璐(译) 张逸驰(译) 黄丽(译) 韩阅(译) 2012中华神经科杂志2012,45,5:52
3WONCA研究论文摘要汇编——急性颅内出血后血压变异性及转归:INTERACT2研究的析因分析,一项随机对照试验显示文摘背景高血压是急性脑卒中的预后因子,血压变异性或许可以独立预测脑卒中的转归。我们评估了血压变异性对INTERACT2参试者脑卒中预后的预测价值, INTERACT2是一项开放标签随机对照试验。方法 INTERACT2将患有自发性颅内出血(ICH)、高收缩压(150~220 mm Hg)、对早期降压强化疗法无明确适应证或禁忌证的2839例成人纳入研究。将患者随机分为强化治疗组(经静脉给药,1 h内目标收缩压降至<140 mm Hg )和指南推荐的治疗组( ICH 后6 h 内,目标收缩压降至<180 mm Hg)。主要转归为死亡或90 d内发生生活大部分无法自理(改良Rankin量表评分≥3分);次要转归为90 d内改良Rankin量表评分发生顺序移动,调查员在评分时并不知晓患者接受了哪种治疗。根据标准定义血压变异性:在发病头24 h (超急性期)进行5次测量,在发病后2~7 d (急性期)进行不少于12次的测量。采用比例优势逻辑回归模型评价血压变异性与转归之间的关联。血压变异性关键指标为收缩压的标准差,按五分位数加以分类。发现研究者对2645例(93.2%)处于超急性期的患者和2347例(82.7%)处于急性期的患者进行了调查。将两个治疗组的数据一起分析,在超急性期〔最高五分位数校正OR=1.41,95%CI (1.05,1.90); P=0.0167〕和急性期〔最高五分位数校正OR=1.57,95%CI (1.14,2.17); P=0.0124〕,收缩压的标准差与主要转归均呈线性相关。对转归最强的预测指标为超急性期最高收缩压和急性期收缩压的标准差为结果的最强预示因子。对次要转归进行分析,得到的结果与以上结果相似〔超急性期最高五分位数,校正OR=1.43,95%CI (1.14,1.80); P=0.0014;急性期OR=1.46,95%CI (1.13,1.88); P=0.0044〕。解释收缩压变异性似乎可预测急性颅内出血患者的不良转归。早期治疗将收缩压降至140 mm Hg以下获得的收益,可通过平稳并持续血压控制进行强化,避免出现收缩压峰值尤为重要。Manning L Hirakawa Y Arima H 周淑新 2014中国全科医学2014,17,21:56
46061铝合金表面激光熔覆温度场的模拟与验证显示文摘根据激光熔覆的特点,建立了移动激光高斯热源作用下三维激光熔覆温度场的计算模型,利用有限元软件ANSYS对温度场分布进行了动态模拟。结果表明,激光熔覆温度场模拟等温线呈椭圆形,在移动热源的前方等温线密集,温度梯度较大,热源后方的等温线稀疏,温度梯度较小。采用高功率连续波Nd:YAG激光在6061铝合金表面激光熔覆SiC陶瓷粉末,形成SiCp/Al金属基复合材料改性层,熔覆层除含有Al,SiC之外,还含有少量的Al4C3,Al4SiC4相,通过熔覆层组织形貌观察及相结构分析验证了模拟结果的准确性和可靠性,为陶瓷—金属基复合材料激光熔覆工艺参数的优化提供了理论依据。张松 张春华 张宁 于莉丽 刘常升 Man H C 2007焊接学报2007,28,10:13
56061铝合金表面激光熔覆温度场的仿真模拟显示文摘利用连续波Nd:YAG固体激光在6061铝合金表面激光熔覆SiC陶瓷粉末,采用ANSYS有限元软件对6061铝合金激光熔覆过程中热量传递及温度场分布进行模拟,在分析过程中采用三维单元,并考虑了材料热物性的非线性及对流和辐射的边界条件,建立了有限元模型,得出了熔覆过程中试样表面的温度分布模拟图.结果表明,温度场模拟等温线呈椭圆形,在移动热源的前方等温线密集,温度梯度较大,热源后方的等温线稀疏,温度梯度较小,熔池内最高温度与激光扫描速度、光斑半径均成反比,与激光功率成正比.模拟结果为陶瓷-金属基复合材料激光熔覆工艺参数的优化提供了理论依据.张春华 张宁 张松 刘常升 Man H C 2007沈阳工业大学学报2007,29,3:8
6Uteroglobin基因G38A多态性与IgA肾病相关关系显示文摘【目的】 研究Uteroglobin 基因G38A多态性与我国IgA肾病的相关关系? 【方法】 用PCR-RFLP法和PCR产物直接测序法鉴定基因型,采用以家庭为基础的传递不平衡检验(transmission disequilibrium test ,TDT)?单倍体相对风险(haplotype-based haplotype relative risk, HRR)分析,以及病例-对照研究分析Uteroglobin 基因G38A多态性与我国IgA肾病的相关关系?【结果】 ① GG基因型在IgA肾病伴高血压组与肾功能进展组中的分布频率显著高于AA +GA(P=0.042,χ2=4.117;P=0.039,χ2=4.240)(病例组362例?正常对照组201例);② 135个满足TDT分析的核心家庭中,杂合子父母传递给患病子代的等位基因频率不比预期值高(χ2=0.457, P=0.499);③ HRR分析显示此多态性不使患者具有更高的发病风险(χ2=0.520, P=0.471, HRR=0.878)?【结论】 Uteroglobin GG基因型可能和IgA肾病的进展及高血压相关,但和IgA肾病的易感性不相关?杜勇 李幼姬 李彩霞 郭辉 Joseph CK Leung Man F Lam 杨念生 黄锋先 方积乾 Patrick H Maxwell 黎嘉能 王一鸣 2004中山大学学报(医学科学版)2004,25,3:4
7National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales.Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser 2021Forest Ecosystems2021,8,1:2
8Laser transformation hardening of AISI440C martensitic stainless steel for higher cavitation erosion resistance显示文摘Lo K H Cheng F T Man H C 2003Surface and Coating Technology2003,173,:2
9Health risk assessment of abandoned agricultural soils based on heavy metal contents in Hong Kong, the world’s most populated city显示文摘Yu Bon Man Xiao Lin Sun Yin Ge Zhao Brenda Natalia Lopez Shan Shan Chung Sheng Chun Wu Kwai Chung Cheung Ming H Wong 2010Environment International2010,,6:2
10Hydrogen effect on the cavitation erosion resistance of AISI 316L stainless steel laser surface modified with NiTi显示文摘Chiu K Y C F T Man H C 2007Materials Letters2007,61,1:1
11Microstructure and formation mechanism of in situ synthesized TiC/Ti surface MMC on Ti-6Al-4V by laser cladding显示文摘 Zhang S Cheng FT 2001Scripta Materialia2001,,44:1
12Upregulation of Glypican-3 expression in hepatocellular carcinoma but downregulation in cholangiocarcinoma indicates its differential diagnosis value in primary liver cancers显示文摘MAN X B TANG L ZHANG B H 2005Liver Int2005,25,5:1
13Mitogenicity of the recombinant myco- bacterial 27-kilodalton lipoprotein is not connected to its anti- protective effect 显示文摘Hovav AH Davidoviteh L Nussbaum G Mullerad J Fish- man Y Bercovier H 2004Infect Immun2004,72,6:1
14Characteristics, apa tire-forming ability and corrosion resistance of NiTi surface modified by AC anodization 显示文摘WONG M H CHENG F T MAN H C 2007Appl Surface Sci2007,253,18:1
15Determination of suit-able sample sizes for multi-patient based finite element studies显示文摘Radcliffe I A Prescott P Man H S 2007Med Eng Phys2007,29,10:1
16Evaluation of liver hepatic function in patients with hepatocellular carcinoma undergoing hepatectomy显示文摘Lau H Man K Fan ST 1997Br J Surg1997,84,9:1
17Preparation and mechanical properties of ultrafine grained metals显示文摘Gunther B Baal man A Weiss H 1990Journal of materials research1990,5,:1
18A control strategy for a robot with one articulate leg hopping on irregular terrain 显示文摘Vermeulen J Lefebor D De Man H 2000Professional Engineering Publishing2000,,10:1
19Non-singular terminal sliding mode control of rigid manipulators显示文摘Feng Y Yu X H Man Z H 2002Automatica2002,38,12:1
20The effect of excimer laser surface treatment on the pitting corrosion fatigue behaviour of alnminium alloy 7075 显示文摘Chan C P Yue T M Man H C 2003Journal of Materials Science2003,15,12:1
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