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| 1 | Terlipressin and hepatorenal syndrome: What is important for nephrologists and hepatologists显示文摘Hepatorenal syndrome (HRS) is a reversible form of functional renal failure that occurs with advanced hepatic cirrhosis and liver failure. Despite mounting research in HRS, its etiology and medical therapy has not been resolved. HRS encompasses 2 distinct types. Type 1 is characterized by the rapid development of renal failure that occurs within 2 wk and involves a doubling of initial serum creatinine. Type 2 has a more insidious onset and is often associated with ascites. Animal studies have shown that both forms, in particular type 1 HRS, are often precipitated by bacterial infections and cir-culatory changes. The prognosis for HRS remains very poor. Type 1 and 2 both have an expected survival time of 2 wk and 6 mo, respectively. Progression of liver cir-rhosis and the resultant portal hypertension leads to the pooling of blood in the splanchnic vascular bed. The ensuing hyperdynamic circulation causes an ineffective circulatory volume which subsequently activates neuro-hormonal systems. Primarily the sympathetic nervoussystem and the renin angiotensin system are activated, which, in the early stages of HRS, maintain adequate circulation. Both advanced cirrhosis and prolonged ac-tivation of neurohormonal mechanisms result in fatal complications. Locally produced nitric oxide may have the potential to induce a deleterious vasodilatory effect on the splanchnic circulation. Currently medical therapy is aimed at reducing splanchnic vasodilation to resolve the ineffective circulation and maintain good renal per-fusion pressure. Terlipressin, a vasopressin analogue, has shown potential benefit in the treatment of HRS. It prolongs both survival time and has the ability to re-verse HRS in the majority of patients. In this review we aim to focus on the pathogenesis of HRS and its treatment with terlipressin vs other drugs. | Ahmed A Magan Atif A Khalil Mohamed H Ahmed | 2010 | World Journal of Gastroenterology2010，16，41： | 11 |
| 2 | 使用气态臭氧体外处理控制储存埃及带壳花生中黄曲霉和黄曲霉毒素B_(1)的潜力显示文摘研究考察在不同水分活度(aw,0.89~0.97=13.1%~24%水分含量)和体外25℃条件下,气态臭氧(O_(3))对黄曲霉菌株(a)孢子萌发,(b)菌丝生长,(c)产黄曲霉毒素B_(1)(AFB_(1))的影响。此外,以埃及花生为研究对象,在0.93 aw下,带壳花生接种两种浓度的黄曲霉分生孢子(103、105分生孢子/g)置于气态O_(3)中然后储存。在所有情况下,臭氧处理设置为30 min,流速为6 L/min。通常,大于100 ppm浓度的O_(3)48 h内,可显著抑制黄曲霉菌株(EGP-B07;SRRC-G 1907)在特定酵母蔗糖培养基上的分生孢子萌发。然而,浓度高达300 ppm的O_(3),对黄曲霉的生长和菌落的扩展没有影响。相同浓度在0.89 aw时能显著影响AFB_(1)的产生。0.93 aw条件下,储存带壳花生中的两种黄曲霉菌株在100~400 ppm O_(3)的数量显著减少。然而,两接种量水平下,AFB_(1)产量仅在400 ppm O_(3)处理中显著降低。对使用O_(3)气体控制采后带壳花生中的黄曲霉种群和AFB_(1)的结果进行了讨论。 | Yousef Sultan Naresh Magan | 2021 | 粮油食品科技2021，29，6： | 3 |
| 3 | Influence of antiviral therapy in the long‐term outcome of recurrent hepatitis C virus infection following liver transplantation显示文摘 | A. García‐Reyne C. Lumbreras I. Fernández F. Colina M. Abradelo P. Magan R. San‐Juan A. Manrique F. López‐Medrano A. Fuertes M. Lizasoain E. Moreno J.M. Aguado | 2013 | Transpl Infect Dis2013，，4： | 2 |
| 4 | Milk-sense: a volatile sensing system reeognises spoilage bacteria and yeasts in milk显示文摘 | MAGAN N PAVLOU A CHRYSANTHAKIS I | 2001 | Sensors and Actuators B-Chemical2001，72，1： | 1 |
| 5 | European research on ochratoxin A in grapes and wine显示文摘 | Battilani P Magan N Logrieco A | 2006 | Int J Food Microbiol2006，111，： | 1 |
| 6 | Recognition of anaerobic bacterial isolates in vitro using electronic nose technology显示文摘 | Pavlou A Turner A P F Magan N | 2002 | Letters in applied microbiology2002，35，5： | 1 |
| 7 | Catalytic diesel particulate filter显示文摘 | Y Nguyen Huu Nhon H Mohamed Magan C Petit | 2003 | Applied Catalysis B, Environmental2003，，2： | 1 |
| 8 | Use of an electronic nose forthe early detection and differentiation between spoilage fungi 显示文摘 | KESHRI G MAGAN N VOYSEY P | 1998 | Letters in applied Microbiology1998，27，： | 1 |
| 9 | Impact of environment and interspecific interactions between spoilage fungi and Aspergillus ochraeeus on growth and ochratoxin production in maize grain显示文摘 | Lee H B Magan N | 2000 | International Journal of Food Microbiology2000，61，： | 1 |
| 10 | Electroactivity of natural and synthetic triphylite显示文摘 | Ravet N Chouinard Y Magan J F | 2001 | J Power Sources2001，9798，： | 1 |
| 11 | Post-harvest control strategies:minimi-zing mycotoxins in the food chain显示文摘 | Magan N Aldred D | 2007 | International Journal ofFood Microbiology2007，119，12： | 1 |
| 12 | Electronic Noses and Disease Diagnostics显示文摘 | Turner A P F Magan N | 2004 | Nature Reviews Microbiology2004，2，： | 1 |
| 13 | Relationship between growth and mycotoxin production by Fusarium species,biocides and environment显示文摘 | Magan N Hope R Baxter E S | 2002 | European Journal of Plant Pathology2002，108，： | 1 |
| 14 | Production cost of a real microalgae production plant and strategies to reduce it显示文摘 | Acien F G Fernandez J M Magan J J | | 0，，： | 1 |
| 15 | Impact of environmental factors on fungal res- piration and dry matter losses in wheat straw 显示文摘 | Willcock J Magan N | 2000 | Journal of Stored Products Research2000，37，： | 1 |
| 16 | Environmental factors and weak organic acid interactions have differential effects on control of growth and ochratoxin A production by Penicillium verrucosum isolates in bread显示文摘 | Mariona Arroyo David Aldred Naresh Magan | 2005 | Int J Food Microbiol2005，98，3： | 1 |
| 17 | Control of the an- thracnose pathogen of banana ( Colletotrichum musae) u- sing antioxidants alone and in combination with thiaben- dazole or imazalil 显示文摘 | KHAN S H AKED J MAGAN N | 2001 | Plant Pathology2001，50，5： | 1 |
| 18 | Eco- physiology of Fusarium culmorum and mycotoxin production 显示文摘 | Naresh Magan Russell Hope David Aldred | 2006 | Advances in Experimental Medicine and Biology2006，，571： | 1 |
| 19 | Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature显示文摘 | Markus Schmidt-Heydt Ahmed Abdel-Hadi Naresh Magan Rolf Geisen | 2009 | International Journal of Food Microbiology2009，，3： | 1 |
| 20 | Soil volatile fingerprints: use for discrimination between soil types under different environmental conditions 显示文摘 | Bastos A C Magan N | 2007 | Sensors and Actuators2007，125，2： | 1 |
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