|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Approach to early-onset colorectal cancer:Clinicopathological,familial,molecular and immunohistochemical characteristics显示文摘AIM:To characterize clinicopathological and familial features of early-onset colorectal cancer(CRC) and compare features of tumors with and without microsatellite instability(MSI).METHODS:Forty-five patients with CRC aged 45 or younger were included in the study.Clinical information,a three-generation family history,and tumor samples were obtained.MSI status was analyzed and mismatch repair genes were examined in the MSI families.Tumors were included in a tissue microarray and an immunohistochemical study was carried out with a panel of selected antibodies.RESULTS:Early onset CRC is characterized by advanced stage at diagnosis,right colon location,low-grade of differentiation,mucin production,and presence of polyps.Hereditary forms represent at least 21% of cases.Eighty-one percent of patients who died during followup showed a lack of expression of cyclin E,which could be a marker of poor prognosis.β-catenin expression was normal in a high percentage of tumors.CONCLUSION:Early-onset CRC has an important familial component,with a high proportion of tumors showing microsatellite stable.Cyclin E might be a poor prognosis factor. | Jose Perea Edurne Alvaro Yolanda Rodríguez Cristina Gravalos Eva Sánchez-Tomé Barbara Rivera Francisco Colina Pablo Carbonell Rogelio González-Sarmiento Manuel Hidalgo Miguel Urioste | 2010 | World Journal of Gastroenterology2010，16，29： | 3 |
| 2 | A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease显示文摘 | C. Fernández-Miranda M. Pérez-Carreras F. Colina G. López-Alonso C. Vargas J.A. Solís-Herruzo | 2007 | Digestive and Liver Disease2007，，3： | 2 |
| 3 | Influence of antiviral therapy in the long‐term outcome of recurrent hepatitis C virus infection following liver transplantation显示文摘 | A. García‐Reyne C. Lumbreras I. Fernández F. Colina M. Abradelo P. Magan R. San‐Juan A. Manrique F. López‐Medrano A. Fuertes M. Lizasoain E. Moreno J.M. Aguado | 2013 | Transpl Infect Dis2013，，4： | 2 |
| 4 | Scarlet fever outbreak in a public school in Granada in 2012显示文摘 | FERNNDEZ-PRADA M MART COLINA LOPEZ A | 2014 | An Pedialr (Barc)2014，80，4： | 1 |
| 5 | Propionibacterium acnes and SAPHO syndrome:a case report and literature review显示文摘 | Colina M Lo Monaco A Khodeir M | 2007 | Clin Exp Rheumatol2007，25，3： | 1 |
| 6 | Spent mushroom substrates influence soil quality and nitrogen availability in a semiarid vineyard soil 显示文摘 | Peregrina F Larrieta C Colina M | 2013 | Soil Acience Society of America Journal2013，，76： | 1 |
| 7 | SAPHO syndrome and infections显示文摘 | Govoni M Colina M Massara A | 2009 | Autoimmun Rev2009，8，3： | 1 |
| 8 | Ho- mografts and xenografts tbr right ventricular outflow tract re- construction: long-term results 显示文摘 | Christenson JT Sierra J Colina Manzano NE | 2010 | Ann Thorac Surg2010，90，： | 1 |
| 9 | Clinical and radiologic evolution of synovitis,acne,pustulosis,hyperostosis,and osteitis syndrome:a single center study of a cohort of 71subjects显示文摘 | Colina M Govoni M Orzincolo C | 2009 | Arthritis Rheum2009，61，6： | 1 |
| 10 | Dietary manipulation to reduce aerial ammonia concentrations in nursery pig facilities显示文摘 | J J Colina A J Lewis P S Miller | 2001 | Anim Sci2001，79，： | 1 |
| 11 | Simultaneous measurement of thyroxine and thyrotropin from newborn dried blood-spot specimens using a multiplexed fluorescent microsphere immunoassay 显示文摘 | Bellisario R Colinas RJ Pass KA | 2000 | Clin Chem2000，46，9： | 1 |
| 12 | Propionibacterium acnes and SAPHO syndrome: a case report and literature review 显示文摘 | Colina M Lo Monaco A Khodeir M | 2007 | Clin Exp RtLeumatol2007，25，： | 1 |
| 13 | Clinieal and radiologic evo- lution of synovitis, aene, pustulosis, hyperostosis, and osteitis syn- drome: a single center study of a cohort of 71 subjects显示文摘 | Colina M Govoni M Orzincolo C | 2009 | Arthritis Care Res2009，61，6： | 1 |
| 14 | A pilot trial of fenofibrate for the treatment of non-alcohofic fatty fiver disease显示文摘 | Fernandez-Miranda C Perez-Carreras M Colina F | 2008 | Dig Liver Dis2008，40，3： | 1 |
| 15 | Dietary manipulation to reduce aerial ammonia concentrations in nursery pig facilities显示文摘 | COLINA J J LEVIS A J MILLER P S | 2001 | Journal of Animal Science2001，79，12： | 1 |
| 16 | Propionibacterium acnes and SAPHO syndrome: a case report and literature review 显示文摘 | Colina M Lo Monaco A Khodeir M | 2007 | Clin Exp Rheumatol2007，，25： | 1 |
| 17 | Dietary lVHnipulation to reduce aerial ammonia concentrations in nursery pig facilities显示文摘 | Colina J J Chang E J | 2001 | Anita Sci2001，79，12： | 1 |
| 18 | Epithelial tumors of the ovary (report of 164 cases) 显示文摘 | De Agustin PP Colina F Martinez TFJ | 1977 | Acta Obstet Ginecol Hisp Lusit1977，25，： | 1 |
| 19 | SAPHO syndrome and infections 显示文摘 | Govoni M Colina M | 2009 | Autoim- munity reviews2009，，8： | 1 |
| 20 | Domestic wastewater treatment using a UASB reactor 显示文摘 | Behling E Diaz A Colina G | 1997 | Bioresour Technol1997，61，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员