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| 1 | Endoscopic management of postoperative bile leaks显示文摘BACKGROUND: Significant bile leak as an uncommon complication after biliary tract surgery may constitute a serious and difficult management problem. Surgical management of biliary fistulae is associated with high morbidity and mortality. Biliary endoscopic procedures have become the treatment of choice for management of biliary Gstulae. METHODS: Ninety patients presented with bile leaks after cholecystectomy ( open cholecystectomy in 45 patients, cholecystectomy with common bile duct exploration in 20 and laparoscopic cholecystectomy in 25). The presence of bile leaks was confirmed by ERCP and the appearance of bile in percutaneous drainage of abdominal collections. Of the 90 patients with postoperative bile leaks, 18 patients had complete transaction of the common bile duct by ERCP and were subjected to bilioenteric anastomosis. In the remaining patients after cholangiography and localization of the site of bile leaks. therapeutic procedures like sphinctero-tomy, biliary stenting and nasobiliary drainage ( NBD ) were performed. If residual stones were seen in the common bile duct, sphincterotomy was followed by stone extraction using dormia basket. Nasobiliary drain or stents of 7F size were placed according to the standard techniques. The NBD was removed when bile leak stopped and closure of the fistula confirmed cholangiographically. The stents were removed after an interval of 6-8 weeks. RESULTS: Bile leaks in 72 patients occurred in the cystic duct (38 patients), the common bile duct (30 ), and the right hepatic duct (4). Of the 72 patients with post-operative bile leak, 24 had associated retained common bile duct stones and 1 had ascaris in common bile duct. All the 72 patients were subjected to therapeutic procedures including sphincterotomy with stone extraction followed by biliary stenting (24 patients), removal of ascaris and biliary stenting (1), sphincterotomy with biliary stenting (18), sphincterotomy with NBD (12), biliary stenting alone (12), and NBD alone (5). Bile leaks stopped in all patients at a median interval of 3 days (range 3-16 days) after endoscopic in- terventions. No difference was observed in efficacy and in time for the treatment of bile leak by sphincterotomy with endoprosthesis or endoprosthesis alone in patients with bile leak after surgery. CONCLUSIONS: Post-cholecystectomy bile leaks occur most commonly in the cystic duct and associated common bile duct stones are found in one-third of cases. Endoscopic therapy is safe and effective in the management of bile leaks and fistulae after surgery. Sphincterotomy with endoprosthesis or endoprosthesis alone is equally effective in the management of postoperative bile leak. | Naresh Agarwal Barjesh Chander Sharma Sanjay Garg Rakesh Kumar Shiv K Sarin | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，2： | 33 |
| 2 | 沼液灌溉对紫色土菜地土壤特性的影响显示文摘三峡库区山地城镇重肥效的沼液灌溉,既需做到能够充分利用粪污资源,又要不破坏植物的生长与土壤环境。试验采用某大型奶牛养殖场粪污处理站不同阶段的废水进行灌溉,其中包括:沉砂池污水(grit chamber wastewater,GCW)、集水池污水(collection basin wastewater,CBW)、厌氧池沼液(anaerobic tank wastewater,ATW)、好氧池出水(aerobic effluent,AE),并以清水(clean water,CW)作为对照组,5组试验平行同步对紫色土试验样地进行灌溉。土壤剖面铵态氮含量在0~5cm土层ATW为最大860mg/kg,5~10cm土层5个试验组含量略有升高,10~20cm土层试验组GCW、CBW、ATW、AE呈下降趋势。硝态氮含量在0~5cm土层仍是ATW最大为23.95mg/kg。有效磷在0~5cm土层5组试验都低于100mg/kg,5~10cm土层试验组CBW和CW含量上升较大分别为10%和11%,5个试验组总体磷吸收能力都为弱。在沼灌土壤自身承载量的试验中,土壤承载铵态氮最大值为1355mg/kg,硝态氮24.65mg/kg,有效磷为163.66mg/kg,磷吸收系数在第5~9d高于500。通过前期不同阶段污水灌溉研究氮、磷积累吸附及土壤自身承载力的试验,确定沼液灌溉能提供较多有效氮、磷的优良可行性,并为进一步提出合理灌溉量和实际操作提供指导。 | 余薇薇 张智 罗苏蓉 毕生兰 Naresh Singhal | 2012 | 农业工程学报2012，28，16： | 20 |
| 3 | Metabolomic studies of human gastric cancer:Review显示文摘Metabolomics is a field of study in systems biology that involves the identification and quantification of metabolites present in a biological system. Analyzing metabolic differences between unperturbed and perturbed networks, such as cancerous and noncancerous samples, can provide insight into underlying disease pathology, disease prognosis and diagnosis. Despite the large number of review articles concerning metabolomics and its application in cancer research, biomarker and drug discovery, these reviews do not focus on a specific type of cancer. Metabolomics may provide biomarkers useful for identification of early stage gastric cancer, potentially addressing an important clinical need. Here, we present a short review on metabolomics as a tool for biomarker discovery in human gastric cancer, with a primary focus on its use as a predictor of anticancer drug chemosensitivity, diagnosis, prognosis, and metastasis. | Naresh Doni Jayavelu Nadav S Bar | 2014 | World Journal of Gastroenterology2014，20，25： | 19 |
| 4 | Endoscopic management of acute cholangitis in elderly patients显示文摘AIM: To evaluate clinical presentation, etiology, compli-cations and response to treatment in elderly patients with acute cholangitis.METHODS: Demographics, etiology of biliary obstruc-tion, clinical features, complications and associated systemic diseases of 175 patients with acute cholangitis were recorded. Endoscopic biliary drainage was performed using nasobiliary drain or stent. The complications related to ERCP, success of biliary drainage, morbidity, mortality and length of hospital stay were evaluated. RESULTS: Of 175 patients, 52 aged ≥ 60 years (groupⅠ, age < 60 years; group Ⅱ, age ≥ 60 years) and 105 were men. Fever was present in 38 of 52 patients of group Ⅱ compared to 120 of 123 in groupⅠ. High fever (fever ≥ 38.0℃) was more common in groupⅠ(118/120 vs 18/38). Hypotension (5/123 vs 13/52), altered sensorium (3/123 vs 19/52), peritonism (22/123 vs 14/52), renal failure (5/123 vs 14/52) and associated comorbid diseases (4/123 vs 21/52) were more common in group Ⅱ. Biliopancreatic malignancy was a common cause of biliary obstruction in group Ⅱ (n = 34) and benign diseases in groupⅠ(n = 120). Indications for biliary drainage were any one of the following either singly or in combination: a fever of ≥ 38.0℃ (n = 136), hypotension (n = 18), peritonism (n = 36), altered sensorium (n = 22), and failure to improve within 72 h of conservative management (n = 22). High grade fever was more common indication of biliary drainage in groupⅠand hypotension, altered sensorium, peritonism and failure to improve within 72 h of conservative management were more common indications in group Ⅱ. Endoscopic biliary drainage was achieved in 172 patients (nasobiliary drain: 56 groupⅠ, 24 group Ⅱ, stent: 64 groupⅠ, 28 group Ⅱ) without any significant age related difference in the success rate. Abdominalpain, fever, jaundice, hypotension, altered sensorium, peritonism and renal failure improved after median time of 5 d in 120 patients in groupⅠ(2-15 d) compared to 10 d in 47 patients of group Ⅱ (3-20 d). Normalization of leucocyte count was seen after a median time of 7 d (3-20 d) in 120 patients in groupⅠcompared to 15 d (5-26 d) in 47 patients in group Ⅱ. There were no ERCP related complications in either group. Five patients (carcinoma gallbladder n = 3, CBD stones n = 2) died in group Ⅱ and they had undergone biliary drainage after failure of response to conservative management for 72 h. There was a higher mortality in patients in group Ⅱ despite successful biliary drainage (0/120 vs 5 /52). Length of hospital stay was longer in group Ⅱ patients (16.4 ± 5.6, 7-30 d) than in groupⅠpatients (8.2 ± 2.4, 7-20 d).CONCLUSION: Elderly patients with acute cholangitis have a high incidence of severe cholangitis, concomitant medical illnesses, hypotension, altered sensorium, peritonism, renal failure and higher mortality even after successful biliary drainage. | Naresh Agarwal Barjesh Chander Sharma Shiv K Sarin | 2006 | World Journal of Gastroenterology2006，12，40： | 14 |
| 5 | Comparison of phenotypic markers and neural differentiation potential of multipotent adult progenitor cells and mesenchymal stem cells显示文摘AIM: To compare the phenotypic and neural differentiation potential of human bone marrow derived multipotent adult progenitor cells (MAPC) and mesenchymal stem cells (MSC). METHODS: Cultures of MAPC and MSC were established in parallel from same samples of human bone marrow (n = 5). Both stem cell types were evaluated for expression of pluripotency markers including Oct-4 and Nanog by immunocytochemistry and reversetranscription polymerase chain reaction (RT-PCR) and expression of standard mesenchymal markers including CD14, CD34, CD44, CD45, CD73, CD90, CD105 andhuman leukocyte antigen (HLA)-ABC by flow cytometry. After treatment with neural induction medium both MAPC and MSC were evaluated for expression of neural proteins [neuronal filament-200 (NF-200) and glial fibrillar acidic protein (GFAP)] by immunocytochemistry and Western blotting and neural genes [NF-200, GFAP, Tau, microtubule-associated protein (MAP)-1B, MAP-2, neuron-specific enolase (NSE) and oligodendrocyte-1 (Olig-1)] by quantitative real-time-PCR. RESULTS: MAPC had small trigonal shaped while MSC had elongated spindle-shaped morphology. The MAPC expressed Oct-4 and Nanog both at gene and protein levels, whereas MSC were negative for these pluripotent markers. MAPC were negative for HLA-ABC while MSC had high expression of HLA-ABC. In addition, MAPC as compared to MSC had significantly lower expression of CD44 (36.56% ± 1.92% vs 98.23% ± 0.51%), CD73 (15.11% ± 2.24% vs 98.53% ± 2.22%) and CD105 (13.81% ± 3.82%vs 95.12% ± 5.65%) (P < 0.001, for all) MAPC cultures compared to MSC cultures treated with neural induction medium had significantly higher fold change expression of NF-200 (0.64), GFAP (0.52), Tau (0.59), MAP-2 (0.72), Olig-1 (0.18) and NSE (0.29) proteins (P < 0.01 for Olig-1 and P < 0.001 for rest) as well as higher fold change expression of genes of NF-200 (1.34),GFAP (1.12),Tau (1.08),MAP-1B (0.92), MAP-2 (1.14) andNSE (0.4) (P < 0.001 for all). CONCLUSION: MAPC can be differentially characterized from MSC as Oct-4 and Nanog positive stem cells with no expression of HLA-ABC and low expression of mesenchymal markers CD44, CD73 and CD105 and when compared to MSC they possess greater predilection for differentiation into neuro-ectodermal lineage. | Saurabh Pratap Singh Naresh Kumar Tripathy Soniya Nityanand | 2013 | World Journal of Stem Cells2013，5，2： | 10 |
| 6 | Immunoproteome analysis of soluble and membrane proteins of Shigella flexneri 2457T显示文摘AIM: To profile the immunogenic proteins of Shigella flexneri (S. flexneri) expressed during human infection using a proteomic approach. METHODS: Soluble and membrane protein extractions of S. flexneri 2457T were separated by two-dimensional gel electrophoresis (2-DE). Proteins were transferred to PVDF membrane and immunoblotted with sera from shigellosis patients. Reactive protein spots were matched to Coomassie stained gels run in parallel, cut out and trypsin digested. Matrix-assisted laser desorption/ionization time of flight-mass spectrometry (MALDI-TOF-MS) was used to determine the peptide mass fingerprints, which were searched in the MASCOT database to identify the protein. RESULTS: A total of 8 immunoreactive proteins were successfully identified from the Coomassie stained gels in three repeats. Six of these proteins have not previously been reported as immunogenic in S. flexneri. These proteins could be potential candidates for vaccine or attenuation studies. CONCLUSION: Soluble and membrane proteins of S. flexneri 2457T have been screened by 2-DE and immunoblotting with sera from shigellosis patients. Eight proteins are identified as immunogenic. | Amy V Jennison Rubhana Raqib Naresh K Verma | 2006 | World Journal of Gastroenterology2006，12，41： | 9 |
| 7 | Correlation of transient elastography with hepatic venous pressure gradient in patients with cirrhotic portal hypertension: A study of 326 patients from India显示文摘AIM To study the diagnostic accuracy of transient elastography(TE) for detecting clinically significant portal hypertension(CSPH) in Indian patients with cirrhotic portal hypertension.METHODS This retrospective study was conducted at the Institute of Liver, Gastroenterology, and Panceatico-Biliary Sciences, Sir Ganga Ram Hospital, New Delhi, on consecutive patients with cirrhosis greater than 15 years of age who underwent hepatic venous pressure gradient(HVPG) and TE from July 2011 to May 2016. Correlation between HVPG and TE was analyzed using the Spearman's correlation test. Receiver operating characteristic ( ROC) curves were prepared for determining the utility of TE in predicting various stages of portal hypertension. The best cut-off value of TE forthe diagnosis of CSPH was obtained using the Youden index.RESULTS The study included 326 patients [median age 52(range 16-90) years; 81% males]. The most common etiology of cirrhosis was cryptogenic(45%) followed by alcohol(34%). The median HVPG was 16.0(range 1.5 to 30.5) mm Hg. Eighty-five percent of patients had CSPH. A significant positive correlation was noted between TE and HVPG(rho 0.361, P < 0.001). The area under ROC curve for TE in predicting CSPH was 0.740(95%CI: 0.662-0.818)(P < 0.01). A cut-off value of TE of 21.6 k Pa best predicted CSPH with a positive predictive value(PPV) of 93%.CONCLUSION TE has a fair positive correlation with HVPG; thus, TE can be used as a non-invasive modality to assess the degree of portal hypertension. A cut-off TE value of 21.6 k Pa identifies CSPH with a PPV of 93%. | Ashish Kumar Noor Muhammad Khan Shrihari Anil Anikhindi Praveen Sharma Naresh Bansal Vikas Singla Anil Arora | 2017 | World Journal of Gastroenterology2017，23，4： | 8 |
| 8 | Retinal structural-vascular-functional relationship using optical coherence tomography and optical coherence tomography -angiography in myopia显示文摘Background:To examine the retinal structure–vascular-function relationship using optical coherence tomography(OCT)and optical coherence tomography angiography(OCTA)in myopia.Methods:This was a prospective cross-sectional study comprising 86 eyes of 45 individuals with varying axial lengths and spherical equivalents and no posterior segment abnormalities.All eyes underwent optical coherence tomography with the Spectralis SD-OCT and OCTA with RTVue-XR Avanti;Optovue.Individual macular retinal layer thicknesses and flow areas and vessel densities were measured on OCT and OCTA,respectively.Linear correlations were made between the macular layer thicknesses,flow areas and vessel densities with axial length,spherical equivalent and visual acuity.Results:The participants’mean ages were 33.34±14.45 years,mean spherical equivalent refractions were−7.17±5.71 D and axial lengths were 25.95±2.41 mm.There were significant positive correlations of foveal angle(r=0.757,p=0.001),inner retinal(r=0.764,p=0.001)and outer plexiform layer(r=0.771,p=0.001)thickness on OCT and vessel densities in deep capillary plexus(r=0.313,p=0.003)on OCTA with axial length and negative correlations with spherical equivalents and visual acuity.Significant negative correlations of outer nuclear layer(r=−0.560,p=0.03)and photoreceptor outer segment layer thickness(r=−0.856,p<0.001)were noted on OCT with axial length and positive correlations with spherical equivalents and visual acuity.Conclusion:The lateral retinal stretching in myopia could possibly explain the correlation between retinal layer thickness,vascular density and visual acuity in these eyes.Further research is required to investigate this. | Ramesh Venkatesh Shivani Sinha Deepika Gangadharaiah Santosh G.K.Gadde Ashwin Mohan Rohit Shetty Naresh Kumar Yadav | 2019 | Eye and Vision2019，6，1： | 7 |
| 9 | 在稍尖的巨大的肺的栓塞的机械故障和 thrombolysis : 未来的试用显示文摘 AIM: To assess role of combined modality of mechanical fragmentation and intralesional thrombolysis in patients with massive pulmonary embolism presenting subacutely. METHODS: Eight of 70 patients presenting in tertiary care centre of North India with massive pulmonary embolism within 4 years had subacute presentation (symptom onset more than 2 wk). These patients were subjected to pulmonary angiography with intention to treat basis via mechanical breakdown and intra lesional thrombolysis. Mechanical breakdown of embolus was accomplished with 5-F multipurpose catheter to reestablish flow, followed by intralesional infusion of urokinase (4400 IU/kg over 10 min followed by 4400 IU/kg per hour over 24 h). RESULTS: Eight patients, mean age 47.77±12.20 years presented with subacute pulmonary embolism (mean duration of symptoms 2.4 wk). At presentation, mean heart rate, shock index, miller score and mean pulmonary pressures were 101.5±15.2/min, 0.995±0.156, 23.87±3.76 and 37.62±6.67 mmHg which reduced to 91.5±12.2/min (P=0.0325), 0.789±0.139 (P=0.0019), 5.87±1.73 (P=0.0000004) and 27.75±8.66 mmHg (P=0.0003) post procedurally. Mean BP improved from 80.00±3.09 mmHg to 90.58±9.13 mmHg (P=0.0100) post procedurally. Minor complications in the form of local hematoma-minor hematoma in 1 (12.5%), and pseudoaneurysm (due to femoral artery puncture) in 1 (12.5 %) patient were seen. At 30 d and 6 mo follow up survival rate was 100% and all the patients were asymptomatic and in New York Heart Association class 1. CONCLUSION: Combined modality of mechanical fragmentation and intralesional thrombolysis appears to be a promising alternative to high risk surgical procedures in patients with subacute massive pulmonary embolism. | Bishav Mohan Shibba Takkar Chhabra Naved Aslam Gurpreet Singh Wander Naresh Kumar Sood Sumati Verma Anil Kumar Mehra Sarit Sharma | 2013 | World Journal of Cardiology2013，5，5： | 5 |
| 10 | All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's. | Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，7： | 5 |
| 11 | Perspectives of pluripotent stem cells in livestock显示文摘The recent progress in derivation of pluripotent stem cells(PSCs)from farm animals opens new approaches not only for reproduction,genetic engineering,treatment and conservation of these species,but also for screening novel drugs for their efficacy and toxicity,and modelling of human diseases.Initial attempts to derive PSCs from the inner cell mass of blastocyst stages in farm animals were largely unsuccessful as either the cells survived for only a few passages,or lost their cellular potency;indicating that the protocols which allowed the derivation of murine or human embryonic stem(ES)cells were not sufficient to support the maintenance of ES cells from farm animals.This scenario changed by the innovation of induced pluripotency and by the development of the 3 inhibitor culture conditions to support naïve pluripotency in ES cells from livestock species.However,the long-term culture of livestock PSCs while maintaining the full pluripotency is still challenging,and requires further refinements.Here,we review the current achievements in the derivation of PSCs from farm animals,and discuss the potential application areas. | Dharmendra Kumar Thirumala R Talluri Naresh L Selokar Iqbal Hyder Wilfried A Ku | 2021 | World Journal of Stem Cells2021，13，1： | 4 |
| 12 | Countermeasures for local scour at offshore wind turbine monopile foundations:A review显示文摘Local scour at monopile foundations of offshore wind turbines is one of the most critical structural stability issues.This article reviews the contemporary methods of scour countermeasures at monopile foundations.These methods include armouring countermeasures(e.g.,riprap protection)to enhance the anti-scour ability of the bed materials and flow-altering countermeasures(e.g.,collars and sacrificial piles)to reduce downflow or change flow patterns around the monopiles.Stability number and size-selection equations for riprap armour layers are summarised and compared.Moreover,other alternative methods to riprap are briefly introduced and presented.A typical graph of the scour depth reduction with different collar sizes and elevations under specific test conditions is summarised and compared with a plot for a pile founded on a caisson.Reduction rates for different flow-altering countermeasures,including the collar,are listed and compared.A newly developed soil improvement method,namely microbially induced calcite precipitation(MICP),is also reviewed and introduced as a scour protection method.As a popular bio-soil treatment method,MICP has a good potential as a scour countermeasure method.Bio-soil treatment methods and traditional armouring methods are defined as active and passive soil enhancement scour countermeasures,respectively. | Zi-hao Tang Bruce Melville Naresh Singhal Asaad Shamseldin Jin-hai Zheng Da-wei Guan Liang Cheng | 2022 | Water Science and Engineering2022，15，1： | 4 |
| 13 | Indian medicinal herbs as sources of antioxidants显示文摘 | Shahin Sharif Ali Naresh Kasoju Abhinav Luthra Angad Singh Hallihosur Sharanabasava Abhishek Sahu Utpal Bora | 2007 | Food Research International2007，，1： | 4 |
| 14 | Layer-by-layer assembled dual-ligand conductive MOF nano-films with modulated chemiresistive sensitivity and selectivity显示文摘In this paper,a dual-ligand design strategy is demonstrated to modulate the performance of the electronically conductive metalorganic frameworks(EC-MOFs)thin film with a spray layer-by-layer assembly method.The thin film not only can be precisely prepared in nanometer scale(20-70 nm),but also shows the pin-hole-free smooth surface.The high quality nano-film of 2,3,6,7,10,11-hexaiminotriphenylene(HITP)doped Cu-HHTP enables the precise modulation of the chemiresistive sensitivity and selectivity.Selectivity improvement over 220%were realized for benzene vs.NH3>as well as enhanced response and recovery properties.In addition,the selectivity of the EC-MOF thin film sensors toward other gases(e.g.triethylamine,methane,ethylbenzene,hydrogen,butanone,and acetone)vs.NH3 at room temperature is also discussed. | Ai-Qian Wu Wen-Qing Wang Hong-Bin Zhan Lin-An Cao Xiao-Liang Ye Jia-Jia Zheng Pendyala Naresh Kumar Kashi Chiranjeevulu Wei-Hua Deng Guan-E Wang Ming-Shui Yao Gang Xu | 2021 | Nano Research2021，14，2： | 3 |
| 15 | An account of the strategies to enhance the water splitting efficiency of noble-metal-free electrocatalysts显示文摘The electrolysis of water for hydrogen generation has shown immense promise as an energy conversion technology for the green energy economy.Two concurrently occurring electrochemical reactions in water electrolysis(hydrogen and oxygen evolution reactions)are sluggish in nature and therefore the employment of electrocatalysts is highly essential.Noble-metal-based electrocatalysts(Pt,Ru O_(2),Ir O_(2),etc.)have shown superior activity towards these reactions.However,their lower natural abundance and inferior stability make the cost to performance ratio of water electrolysis too high.Thus,huge amount of research efforts are being carried out to develop electrocatalysts consisting of earth abundant elements(transition metals,carbon etc.)as the replacement of these noble-metal-based materials.Transition metal compounds,carbonaceous and hybrid materials have shown promise as efficient electrocatalysts but there is still huge gap between the activities of these materials and the noble-metal-based electrocatalysts.Several strategies like morphology modulation,elemental doping,defect engineering etc.are being deployed to enhance the activity of these noble-metal-free electrocatalysts.This review summarizes these strategies and thoroughly discusses the reason behind the changes in activity of the electrocatalysts owing to these modifications.Finally,the remaining research gaps and future prospects in this field are also discussed in detail. | Subhasis Shit Saikat Bolar Naresh Chandra Murmu Tapas Kuila | 2021 | Journal of Energy Chemistry2021，30，8： | 3 |
| 16 | Socio-economic and Environmental Implications of the Hydroelectric Projects in Uttarakhand Himalaya, India显示文摘This paper deals with detailed analysis of the fiasco created by the Tehri High Dam in Uttarakhand, India, particularly in terms of resettlement and rehabilitation of the local inhabitants. Aspects pertaining to the environmental issues are also discussed. Currently, the river valleys in Uttarakhand state of India are the targets of increasing hydroelectric projects. Virtually all rivers are being exploited for generating environmental friendly power. Having being learned the hard lesson from Tehri Dam, it has been decided to opt for such schemes in which comparatively little submergence and tempering with the fragile eco-systems is involved.However, our observations suggest that even in such schemes if due care is not taken they may turn out to be a failure. | Naresh Rana S. P. Sati Y.P. Sundriyal Madan Mohan Doval Navin Juyal | 2007 | Journal of Mountain Science2007，4，4： | 3 |
| 17 | Synthesis of CsPbX_(3)(X=Cl/Br,Br,and Br/I)@SiO_(2)/PM M A composite films as color-conversion materials for achieving tunable multi-color and white light emission显示文摘All-inorganic cesium lead halide based perovskite nanocrystals(PNCs)exhibit promising optoelectronic properties,but their poor stability and anion exchange reaction limit their broad commercial applications.Herein,we demonstrated the successful synthesis of blue-green-red emitting CsPbX_(3)(X=Cl/Br,Br,and Br/I)PNCs via hot injection method,followed by silica-coating and embedding in poly(methylmethacrylate)(PMMA)matrix.The photoluminescence(PL)spectra of SiO_(2)/PMMA-coated PNCs can be tuned continuously by regulating precursor composition ratio,from blue(CsPb(Cl_(0.5)/Br_(0.5))_(3);460 nm)to red(CsPb(Br_(0.4)/I_(0.6))_(3)via green(CsPbBr_(3);519 nm).The PNCs composite films exhibit improved stability(thermal-,moisture-,and photo-stability)because of the barrier formed by Si0_(2)/PMMA coating and also displayed exceptional photoluminescent quantum yield(PLQY of blue,green,and red-emitting Si0_(2)/PMMA coated PNCs are 37%,86%,and 71%,respectively)with longer lifetimes inhibiting anion exchange.Eventually,the PNCs-encapsulated Si0_(2)/PMMA composite films were integrated into the UV LED chip as down-converting materials to construct a prototype white-peLED unit.The designed white-peLED unit demonstrated bright white light generating CIE coordinates(0.349,0.350),a luminous efficiency(LE)of 39.2%and a color rendering index(CRI)of 84.7.The wide color gamut of 121.47%of NTSC and 98.56%of Rec.2020 is also achieved with the built w-LED system.Therefore,the results demonstrated that CsPbX_(3)(X=Cl/Br,Br,and Br/I)PNCs@SiO_(2)/PMMA composite films can be employed as efficient UV to visible color conversion materials for white-LEDs and backlighting. | Varnakavi Naresh Byung Hyo Kim Nohyun Lee | 2021 | Nano Research2021，14，4： | 3 |
| 18 | 使用气态臭氧体外处理控制储存埃及带壳花生中黄曲霉和黄曲霉毒素B_(1)的潜力显示文摘研究考察在不同水分活度(aw,0.89~0.97=13.1%~24%水分含量)和体外25℃条件下,气态臭氧(O_(3))对黄曲霉菌株(a)孢子萌发,(b)菌丝生长,(c)产黄曲霉毒素B_(1)(AFB_(1))的影响。此外,以埃及花生为研究对象,在0.93 aw下,带壳花生接种两种浓度的黄曲霉分生孢子(103、105分生孢子/g)置于气态O_(3)中然后储存。在所有情况下,臭氧处理设置为30 min,流速为6 L/min。通常,大于100 ppm浓度的O_(3)48 h内,可显著抑制黄曲霉菌株(EGP-B07;SRRC-G 1907)在特定酵母蔗糖培养基上的分生孢子萌发。然而,浓度高达300 ppm的O_(3),对黄曲霉的生长和菌落的扩展没有影响。相同浓度在0.89 aw时能显著影响AFB_(1)的产生。0.93 aw条件下,储存带壳花生中的两种黄曲霉菌株在100~400 ppm O_(3)的数量显著减少。然而,两接种量水平下,AFB_(1)产量仅在400 ppm O_(3)处理中显著降低。对使用O_(3)气体控制采后带壳花生中的黄曲霉种群和AFB_(1)的结果进行了讨论。 | Yousef Sultan Naresh Magan | 2021 | 粮油食品科技2021，29，6： | 3 |
| 19 | Pyoderma Gangrenosum with Oral Involvement–Case Report and Review of the Literature显示文摘Pyoderma gangrenosum (PG) is a rare, noninfectious neutrophilic dermatosis. Clinically, it begins with sterile pustules that rapidly progress into painful ulcers of variable depth and size with undermined violaceous borders. The diagnosis of PG is based on the history of an underlying disease, a typical clinical presentation, histopathology, and exclusion of other diseases. The peak incidence occurs between the ages of 20 to 50 years with women being more often affected than men. There have been very few reports of pyoderma gangrenosum with oral mucosal involvement. Oral lesions in previously reported cases have included ulcers of varying sizes from a few mm to several cm and have been reported to have been found on the tongue, soft and hard palate, buccal mucosa, and gingiva. Some of these oral lesions have been associated with ulcerative colitis, inflammatory bowel disease, and polycythemia rubra vera. A few cases were reported with biopsy findings, the histological picture being nonspecific, showing ulceration, and necrosis with inflam- matory cell infiltrate. A peculiar case of pyoderma gan- grenosum with an oral lesion is presented here, and the differential diagnosis is discussed. | Geetha Paramkusam Venkateswarlu Meduri Naresh Gangeshetty | 2010 | International Journal of Oral Science2010，2，2： | 2 |
| 20 | Online Learning Control for Harmonics Reduction Based on Current Controlled Voltage Source Power Inverters显示文摘Nonlinear loads in the power distribution system cause non-sinusoidal currents and voltages with harmonic components.Shunt active filters(SAF) with current controlled voltage source inverters(CCVSI) are usually used to obtain balanced and sinusoidal source currents by injecting compensation currents.However,CCVSI with traditional controllers have a limited transient and steady state performance.In this paper,we propose an adaptive dynamic programming(ADP) controller with online learning capability to improve transient response and harmonics.The proposed controller works alongside existing proportional integral(PI) controllers to efficiently track the reference currents in the d-q domain.It can generate adaptive control actions to compensate the PI controller.The proposed system was simulated under different nonlinear(three-phase full wave rectifier) load conditions.The performance of the proposed approach was compared with the traditional approach.We have also included the simulation results without connecting the traditional PI control based power inverter for reference comparison.The online learning based ADP controller not only reduced average total harmonic distortion by 18.41%,but also outperformed traditional PI controllers during transients. | Naresh Malla Ujjwol Tamrakar Dipesh Shrestha Zhen Ni Reinaldo Tonkoski | 2017 | IEEE/CAA Journal of Automatica Sinica2017，4，3： | 2 |
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