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| 1 | EEG bispectal index and hypnotic component of anaesthesia induced by sevoflurane:comparison between children and adults显示文摘 | DEGOUTE C S MACABEO C DUBREUIL C | 2001 | Br J Anaesth2001，86，： | 1 |
| 2 | Phy- tochemical survey and pharmacological activities of the in- dole alkaloids in the genus Voacanga thouars (Apocynace- ae) -An update 显示文摘 | Macabeo APG Alejandro GJD Hallare AV | 2009 | Pharmacogn Rev2009，3，5： | 1 |
| 3 | EEG bis- pectral index and hypnotic component of anaesthesia in- duced by sevoflurane: comparison between children and adults显示文摘 | Degoute C S Macabeo C Dubreuil C | 2001 | Br J Anaesth2001，86，2： | 1 |
| 4 | Indole alkaloids from the leaves of Philippine Alstonia sctmlaris 显示文摘 | Macabeo A P G Krohn K Gehle D | 2005 | Phytochemistry2005，66，10： | 1 |
| 5 | EEG bispeetral index and hypnotic component of anaesthesia induced by sevoflurane:comparison be- tween children and adults显示文摘 | Degoute CS Macabeo C Dubreuil C | 2001 | Br J Anaesth2001，86，2： | 1 |
| 6 | Indole alkaloids from the leaves of Philippine Alstonia scholaris显示文摘 | Krohn K Gehle D | 2005 | Phytochemistry2005，66，2： | 1 |
| 7 | Antitubercular constituents from Premna odorata Blanco显示文摘 | Stephen B. Lirio Allan Patrick G. Macabeo Erickson M. Paragas Matthias Knorn Paul Kohls Scott G. Franzblau Yuehong Wang Ma. Alicia M. Aguinaldo | 2014 | Journal of Ethnopharmacology2014，，2： | 1 |
| 8 | Overexpression of matrix metalloproteinase - 1 and - 9 mRNA is associated with progression of oral dysplasia to cancer显示文摘 | Jordan RC Macabeo - Ong M Shiboski CH | 2004 | Clin Cancer Res2004，10，： | 1 |
| 9 | EEG bispectral index and hypnotic component of anaesthesia induced by sevoflurane:comparison between children and adults显示文摘 | Degoute CS Macabeo C Dubreuil C | 2001 | Br J Anaesth2001，86，2： | 1 |
| 10 | A Routing Protocol Based on Node Density for Ad Hoc Networks显示文摘 | Alejandro Quintero Samuel Pierre Benjamin Macabeo | 2005 | International Journal of Quantum Information2005，，3： | 1 |
| 11 | EEG bispectral index and hypnotic component of anaesthesia induced by sevoflurance:comparison between children and adults显示文摘 | Degoute CS Macabeo C Dubreuil C | 2001 | Br J Anaesth2001，86，2： | 1 |
| 12 | Antitubercular activity of the semi-polar extractives of Uvaria rufa显示文摘Objective:To investigate the inhibitory activity of the chloroform extract,petroleum ether and chloroform sub-extracts,lead-acetate treated chloroform extract,fractions and secondary metabolites of Uvaria rufa(U.rufa) against Mycobacterium tuberculosis(M.tuberculosis) H37Rv. Methods:The antituberculosis susceptibility assay was earried out using the colorimetric Microplate Alamar blue assay(MABA).In addition,the cytotoxicity of the most active fraction was evaluated using the VERO cell toxicity assay.Results:The in vitro inhibitory activity against M.tuberculosis H37Rv increased as purification progressed to fractionation(MIC up to 23μg/mL). The chloroform extract and its sub-extracts showed moderate toxicity while the most active fraction from chloroform sub-extract exhibited no cytotoxicity against VERO cells.Meanwhile, the lead acetate-treated crude chloroform extract and its fractions showed complete inhibitions (100%) with MIC values up to 8μg/mL.Phylochemical screening of the most active fraction showed,in general,the presence of terpenoids,steroids and phenolic compounds.Evaluation of the antimycobacterial activity of known secondary metabolites isolated showed no promising inhibitory activity against the test organism.Conclusions:The present results demonstrate the potential of U.rufa as a phytomedicinal source of compounds that may exhibit promising antituberculosis activity.In addition,elimination of polar pigments revealed enhanced inhibition against M.tuberculosis H37Rv.While several compounds known for this plant did not show antimycobacterial activity,the obtained results are considered sufficient reason for further study to isolate the metabolites from U.rufa responsible for the antitubercular activity. | Allan Patrick G Macabeo Florie A Tudla Karsten Krohn Scott G Franzblau | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，10： | 0 |
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