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| 1 | 氮沉降的全球化:对于陆地生态系统的意义显示文摘人类活动产生的氮(N),包括农田氮肥施肥和矿物燃料燃烧过程中所固定的氮,其来源和分布正在迅速地扩展到全球范围。这部分氮进入到陆地生态系统中,将会促进植物的生长,并产生过量的氮,最终通过淋溶和痕量气体排放的形式,增加了氮的损失。在某种情况下,还会导致物种组成的变化和生态系统功能的衰减。但并非所有的生态系统都对氮沉降具有类似的响应。它们的响应情况,取决于氮沉降的连续性、生态系统的类型、生态系统对氮的需求或保持能力、土地利用的历史、土壤状况、地形条件、气候背景以及氮沉降的速度、时间和类型等因素。我们认为,起重要作用的是:一些对人类影响具有显著意义的条件、一些控制生态系统响应变化的因素以及一些由于资料缺乏而使不确定性增大的地方。 | Pamela Matson Kathleen A.Lohse Sharon J.Hall 闵庆文 | 2002 | AMBIO-人类环境杂志2002，31，2： | 71 |
| 2 | Innate immune signaling and regulation in cancer immunotherapy显示文摘先存在的 T 煽动房间的肿瘤微型环境有预示的用途并且能也为对当代的癌症免疫疗法的反应预兆。对联系肿瘤的抗原的自发的 T 房间回答的产生取决于天生的有免疫力的激活,运动打它我干扰素(IFN ) 生产。最近的工作为在这个过程察觉到的 cytosolic DNA 的 STING 小径揭示了一个主要角色。事件的这串联贡献 Batf3 系树枝状的房间(DC ) 的激活,它看起来对反肿瘤免疫中央。Non-T 煽动房间的肿瘤为 Batf3 DC 招募缺乏 chemokines,有很少 Batf3 DC,并且缺乏一种类型我 IFN 基因签名,建议那没有通过天生的有免疫力的激活可以是因缺乏自发的 T 房间激活和累积的最终的原因。与手里的这个信息,为触发天生的有免疫力的激活和 Batf3 DC 招募的新策略正在被开发,包括为 de novo 免疫者 priming 的新奇圈套收缩筋。最终,有效天生的有免疫力的使活跃之物的成功的发展应该扩展能对免疫疗法作出回应的病人的部分,例如与检查点封锁抗体。 | Leticia Corrales Vyara Matson Blake Flood Stefani Spranger Thomas F Gajewski | 2017 | Cell Research2017，27，1： | 13 |
| 3 | Adrenomedullin and endocrine control of immune cells during pregnancy显示文摘怀孕的免疫学复杂、不完全地听说。在蜕膜并且在胎盘的异常有免疫力的活动被相信在怀孕的疾病起一个作用,例如不孕,流产,胎儿的生长限制和 preeclampsia。这里,我们简短由肽荷尔蒙 adrenomedullin 考察子宫的自然漂亮房间人口和他们的功能的内分泌的控制。在基因动物模型的研究在母亲胎儿的接口揭示了 adrenomedullin 剂量的批评重要性,与从两个的细胞贡献位于适当子宫的感受性,培植并且螺线动脉的脉管的改变下面的必要方面的母亲、胎儿的分隔空间。这些基本卓见进串音在之间内分泌并且在母亲胎儿的接口以内的免疫系统可以最终在临床上复杂的怀孕翻译到功能的更好的理解和 dysregulated adrenomedullin 层次的后果。 | Brooke C Matson Kathleen M Caron | 2014 | Cellular & Molecular Immunology2014，11，5： | 4 |
| 4 | Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice显示文摘Pharmacological activation of the xenobiotic-sensing nuclear receptors pregnane X receptor(PXR) and constitutive androstane receptor(CAR) is well-known to increase drug metabolism and reduce inflammation. Little is known regarding their physiological functions on the gut microbiome. In this study, we discovered bivalent hormetic functions of PXR/CAR modulating the richness of the gut microbiome using genetically engineered mice. The absence of PXR or CAR increased microbial richness, and absence of both receptors synergistically increased microbial richness. PXR and CAR deficiency increased the pro-inflammatory bacteria Helicobacteraceae and Helicobacter. Deficiency in both PXR and CAR increased the relative abundance of Lactobacillus, which has bile salt hydrolase activity, corresponding to decreased primary taurine-conjugated bile acids(BAs) in feces, which may lead to higher internal burden of taurine and unconjugated BAs, both of which are linked to inflammation, oxidative stress, and cytotoxicity. The basal effect of PXR/CAR on the gut microbiome was distinct from pharmacological and toxicological activation of these receptors. Common PXR/CAR-targeted bacteria were identified, the majority of which were suppressed by these receptors. h PXR-TG mice had a distinct microbial profile as compared to wild-type mice. This study is the first to unveil the basal functions of PXR and CAR on the gut microbiome. | Mallory Little Moumita Dutta Hao Li Adam Matson Xiaojian Shi Gabby Mascarinas Bruk Molla Kris Weigel Haiwei Gu Sridhar Mani Julia Yue Cui | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 2 |
| 5 | Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1显示文摘 | Yujiang Shi Fei Lan Caitlin Matson Peter Mulligan Johnathan R. Whetstine Philip A. Cole Robert A. Casero Yang Shi | 2004 | Cell2004，，7： | 2 |
| 6 | CpG motifs in bacterial DNA trigger direct B-cell activation 显示文摘 | Krieg A M Yi A K Matson S | 1995 | Nature1995，374，： | 2 |
| 7 | CpG motifs in bacterial DNA trigger direct B-cell activation 显示文摘 | Krieg AM Yi AK Matson S | 1995 | Nature1995，374，： | 2 |
| 8 | CpG motifs in bacteial DNA trigger direct B-cell activation显示文摘 | Yi AK Matson S | 1995 | Nature1995，374，： | 1 |
| 9 | A framework for vulnerability analysis in sustainability science 显示文摘 | Turne B L Kasperson R E Matsone P A | 2003 | PNAS2003，8，： | 1 |
| 10 | Removal of elastic interface multiples from land and ocean bottom data using inverse scattering显示文摘 | Matson K H Weglein A B | 1996 | Annual Meeting Abstracts Society Of Exploration Geophysicists1996，1526，： | 1 |
| 11 | Fluoranthene, but not benzopyrene, interacts with hypoxia resulting in pericardial effusion and lordosis in developing zebrafish显示文摘 | MATSON C W TIMME-LARAGY A R DI GIULIO R T | 2008 | Chemosphere2008，74，1： | 1 |
| 12 | Agricultural runoff fuels large phytoplankton blooms in vulnerable areas of the ocean显示文摘 | Beman J M Arrigo K R Matson P A | 2005 | Nature2005，434，7030： | 1 |
| 13 | DMRTl protects male gonadal cells from retinoid-dependent sexual transdifferentiation显示文摘 | Minkina A Matson CK Lindeman RE | 2014 | Dev Cell2014，29，： | 1 |
| 14 | One-pot Catalytic Conversion of Cellulose and of Woody Biomass Solids to Liquid Fuels显示文摘 | Matson T D Barta K Iretskii A V | 2011 | Journal of the American Chemical Society2011，133，14： | 1 |
| 15 | Software Development Cost Estimation Using Funtion Points 显示文摘 | Matson J Barret B Melliehamp J | 1994 | IEEE Transactions on Software Engineering1994，20，4： | 1 |
| 16 | Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog显示文摘 | Yujiang Shi Fei Lan Caitlin Matson | 2004 | LSDI Cell2004，119，： | 1 |
| 17 | An overview of wavelet estimation using free-surface multiple removal 显示文摘 | | 2000 | The Leading Edge2000，19，1： | 1 |
| 18 | Ecological controls over monoterpene emission from Douglas fir (Pseudotsuga menziesii)显示文摘 | Lerdau M Matson P Fall R | 1995 | Ecology1995，76，： | 1 |
| 19 | Anastomoses of the ovarian and uterine arteries:a potential pitfall and cause of failure of uterine embolization显示文摘 | Matson M Nicholson A Belli AM | 2000 | Cardiovasc Intervent Radiol2000，23，5： | 1 |
| 20 | Human brain infarction: proton MR spectroscopy显示文摘 | Duijn JH Matson GB Maudsley AA | 1992 | Radiology1992，183，3： | 1 |
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