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1Gallbladder motor function, plasma cholecystokinin and cholecystokinin receptor of gallbladder in cholesterol stone patients显示文摘AIM: To study the interactive relationship of gallbladder motor function, plasma cholecystokinin (CCK) and cholecystokinin A receptor (CCK-R) of gallbladder in patients with cholesterol stone disease.METHODS: Gallbladder motility was studied by ultrasonography in 33 patients with gallbladder stone and 10 health subjects as controls. Plasma CCK concentration was measured by radioimmunoassay in fasting status (CCK-f) and in 30 min after lipid test meal (CCK-30).Radioligand method was employed to analyze the amount and activity of CCK-R from 33 gallstone patients having cholecystectomy and 8 persons without gallstone died of severe trauma as controls.RESULTS: The percentage of cholesterol in the gallstone composition was more than 70%. The cholesterol stone type was indicated for the patients with gallbladder stone in this study. Based on the criterion of gallbladder residual fraction of the control group, 33 gallstone patients were divided into two subgroups, contractor group (14 cases)and non-contractor group (19 cases), The concentration of CCK-30 was significantly higher in non-contractor group than that in both contractor group and control group (55.86±3.86 pmol/l vs 37.85±0.88 pmol/l and 37.95±0.74 pmol/L, P<0.01), but there was no difference between contractor group and control group. Meanwhile no significant difference of the concentration of CCK-f could be observed among three groups. The amount of CCK-R was lower in non-contractor group than those in both control group and contractor group (10.27±0.94 fmol/mg vs24.59±2.39 fmol/mg and 22.66±0.55 fmol/mg, P<0.01).The activity of CCK-R shown as KD in non-contractor group decreased compared to that in control group and contractor group. Only was the activity of CCK-R lower in contractor group than that in control group. The ejection fraction correlated closely with the amount of CCK-R (r = 0.9683,P<0.01), and the concentration of CCK-30 correlated negatively with the amount of CCK-R closely (r = -0.9627,P<0.01).CONCLUSION: The distinctive interactive relationship of gallbladder emptying, plasma CCK and CCK-R in gallbladder from this study suggested that the defect of CCK-R may be a key point leading to the impairment of gallbladder motor function and the pathogenesis of cholesterol gallstoneformation may differ in two subgroups of gallstone patient,gallbladder non-contractor group or contractor group.JianZhu Tian-QuanHan ShengChen YuJiang Sheng-DaoZhang 2005World Journal of Gastroenterology2005,11,11:46
2TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine显示文摘Haikuo Zhang Xin Zhang Erin Clark Michelle Mulcahey Stephen Huang Yujiang Geno Shi 2010Cell Research2010,20,12:20
3Polymorphisms at cholesterol 7α-hydroxylase,apolipoproteins B and E and low density lipoprotein receptor genes in patients with gallbladder stone disease显示文摘AIM: To investigate the relationship between gallbladder stone disease (GSD) and single nucleotide polymorphisms of cholesterol 7α-hydroxylase (CYP7A) gene promoter,apolipoprotein (APO) B gene exon 26, APOEgene exon 4 or microsatellite polymorphism of low density lipoprotein receptor (LDLR) gene exon 18.METHODS: Genotypes of CYP7A, APOB, APOE and LDLR genes were determined in 105 patients with GSD diagnosed by B-mode ultrasonography and 274 control subjects.Serum lipids were analyzed with HITACHI 7060 automaic biochemical analyzer.RESULTS: Body mass index (BMI) was significantly higher in patients with GSD (24.47±3.09) than in controls (23.50±2.16).Plasma total cholesterol was lower in patients with GSD (4.66±0.92 mmol/L) than in controls (4.91±0.96 mmol/L),P<0.01 after adjusted for age, sex and BMI. The significantly higher frequency of A allele of CYP7A gene polymorphism and X+ allele of APOBgene polymorphism was seen in GSD patients. Percentages of A allele in patients and controls were 62.86% and 54.38% (P <0.05) and those of X+ allele 8.57% and 4.01% (P<0.01). Subjects with A allele had significantly lower plasma total cholesterol and LDL cholesterol than subjects with CC homozygote. In a multiple variable logistic regression model, the BMI (OR=1.13, 95% CI: 1.05-1.22), A allele (OR=1.48, 95% CI: 1.05-2.09) and X+ allele (OR=2.28, 95% CI: 1.14-4.59) were positively associated with GSD (P <0.05). Plasma total cholesterol (OR=0.69, 95% CI: 0.64-0.74) was negatively related to GSD (P<0.05).CONCLUSION: With an association analysis, it was determined that A allele of CYP7A gene and X+ allele of APOB gene might be considered as risk genes for GSD. These alleles are related with differences of serum lipids among subjects.Multiple-variable logistic regression model analysis showed that besides BMI, GSD was affected by polygenetic factors.But the mechanism for these two alleles responsible for GSD requires further investigations.Zhao-YanJiang Tian-QuanHan Guang-JunSuo Dian-XuFeng ShengChen Xing-XingCai Zhi-HongJiang JunShang YiZhang YuJiang Sheng-DaoZhang 2004World Journal of Gastroenterology2004,10,10:16
4Evaluation Method and Mitigation Strategies for Shrinkage Cracking of Modern Concrete显示文摘The complex compositions and large shrinkage of concrete,as well as the strong constraints of the structures,often lead to prominent shrinkage cracking problems in modem concrete structures.This paper first introduces a multi-field(hydro-thermo-hygro-constraint)coupling model with the hydration degree of cementitious materials as the basic state parameter to estimate the shrinkage cracking risk of hardening concrete under coupling effects.Second,three new key technologies are illustrated:temperature rise inhibition,full-stage shrinkage compensation,and shrinkage reduction technologies.These technologies can efficiently reduce the thermal,autogenous,and drying shrinkages of concrete.There after,a design process based on the theoretical model and key technologies is proposed to control thecracking risk index below the threshold value.Finally,two engineering application examples are provided that demonstrate that concrete shrinkage cracking can be significantly mitigated by adopting the proposed methods and technologies.Jiaping Liu Qian Tian Yujiang Wang Hua Li Wen Xu 2021Engineering2021,7,3:15
5Climate instability in the Yili region, Xinjiang during the last glaciation显示文摘The climate is influenced by westerlies year in year out and the aeolian loess is widespread in the Yili region, the Xinjiang Uygur Autonomous Region. Through the study of the loess section with a thickness of 21.5 m, much useful information about climatic change in this region during the last glaciation was gotten. Grain size analysis of loess samples in the section showed that the climatic change in the Yili region was of instability during the last glaciation and similar to those of the North Atlantic Ocean and Greenland. In correspondence with the Heinrich events, the percentage of the size fraction of loess with grain size less than 10 μm decreased in cold stadials in the Yili region. This result suggests that the westerly wind be strengthened during the cold periods. Compared with the stadials, the content of the loess with grain size less than 10 μm was increased in interstadials, which indicated that the strength of the westerly wind was weakened. It is obvious that the climate was instableYE Wei, DONG Guangrong, YUAN Yujiang & MA Yingjie1. Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China 2. Department of Geography, Zhejiang Normal University, Jinhua 321004, China 3. Institute of Desert Research, Chinese Academy of Sciences, Lanzhou 730000, China 4. Xinjiang Institute of Meteorological Research, Urumqi 830002, China 2000Chinese Science Bulletin2000,45,17:13
6State of charge estimation by finite difference extended Kalman filter with HPPC parameters identification显示文摘State of charge(SOC) is a key parameter of lithium-ion battery. In this paper, a finite difference extended Kalman filter(FDEKF)with Hybrid Pulse Power Characterization(HPPC) parameters identification is proposed to estimate the SOC. The finite difference(FD) algorithm is benefit to compute the partial derivative of nonlinear function, which can reduce the linearization error generated by the extended Kalman filter(EKF). The FDEKF algorithm can reduce the computational load of controller in engineering practice without solving the Jacobian matrix. It is simple of dynamic model of lithium-ion battery to adopt a secondorder resistor-capacitor(2 RC) network, the parameters of which are identified by the HPPC. Two conditions, both constant current discharge(CCD) and urban dynamometer driving schedule(UDDS), are utilized to validate the FDEKF algorithm.Comparing convergence rate and accuracy between the FDEKF and the EKF algorithm, it can be seen that the former is a better candidate to estimate the SOC.HE Lin HU MinKang WEI YuJiang LIU BingJiao SHI Qin 2020Science China(Technological Sciences)2020,63,3:11
7Reconstruction of hydrological changes based on tree-ring data of the Haba River, northwestern China显示文摘Reconstructing the hydrological change based on dendrohydrological data has important implications for understanding the dynamic distribution and evolution pattern of a given river. The widespread, long-living coniferous forests on the Altay Mountains provide a good example for carrying out the dendrohydrological studies. In this study, a regional composite tree-ring width chronology developed by Larix sibirica Ledeb. and Picea obovata Ledeb. was used to reconstruct a 301-year annual(from preceding July to succeeding June) streamflow for the Haba River, which originates in the southern Altay Mountains, Xinjiang, China. Results indicated that the reconstructed streamflow series and the observations were fitting well, and explained 47.5% of the variation in the observed streamflow of 1957–2008. Moreover, floods and droughts in 1949–2000 were precisely captured by the streamflow reconstruction. Based on the frequencies of the wettest/driest years and decades, we identified the 19 th century as the century with the largest occurrence of hydrological fluctuations for the last 300 years. After applying a 21-year moving average, we found five wet(1724–1758, 1780–1810, 1822–1853, 1931–1967, and 1986–2004) and four dry(1759–1779, 1811–1821, 1854–1930, and 1968–1985) periods in the streamflow reconstruction. Furthermore, four periods(1770–1796, 1816–1836, 1884–1949, and 1973–1997) identified by the streamflow series had an obvious increasing trend. The increasing trend of streamflow since the 1970s was the biggest in the last 300 years and coincided with the recent warming-wetting trend in northwestern China. A significant correlation between streamflow and precipitation in the Altay Mountains indicated that the streamflow reconstruction contained not only local, but also broad-scale, hydro-climatic signals. The 24-year, 12-year, and 2.2–4.5-year cycles of the reconstruction revealed that the streamflow variability of the Haba River may be influenced by solar activity and the atmosphere–ocean system.zhang tongwen yuan yujiang chen feng yu shulong zhang ruibo qin li jiang shengxia 2018Journal of Arid Land2018,10,1:8
8Isolation,Characterization,and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province,China显示文摘Crimean-Congo hemorrhagic fever(CCHF)caused by the CCHF virus(CCHFV)is a tick-borne natural focal disease with a mortality rate of approximately 50%.CCHFV is widely prevalent in Africa,southern Asia,the Middle East,and southeast Europe.CCHF outbreaks have been reported previously in Xinjiang province,China,especially in its southern region.Epidemiological surveys conducted on ticks and animals have revealed the presence of CCHFV strains in ticks,rodents,and infected individuals from cities and counties in southern Xinjiang.Phylogenetic analyses revealed that the Chinese CCHFV strains belong to one genotype,based on complete sequences of the S segments of its negative-stranded RNA genome.The present study reports two new CCHFV strains isolated from Hyalomma asiaticum asiaticum ticks collected from Fukang City and Wujiaqu City in the northern region of Xinjiang.Viral characteristics and their evolutionary relationships were analyzed through metagenomic and reverse-transcription PCR analyses;these analyses indicated that the genotype of both strains was different from that of other Chinese strains.Furthermore,previous reports of CCHFV in Xinjiang were reviewed and phylogenetic analyses were performed.CCHFV was found to prevail in Fukang City in Junggar Basin for more than 20 years,and that Fukang City and Wujiaqu City are considered natural reservoirs of different genotypes of CCHFV strains.Our findings facilitate the understanding of CCHFV distribution in Xinjiang province and provide insights into the evolutionary relationships among Chinese CCHFV strains.Yanfang Zhang Shu Shen Yaohui Fang Jinliang Liu Zhengyuan Su Jinhao Liang Zhong Zhang Qiaoli Wu Cheng Wang Abulikemu Abudurexiti Zhihong Hu Yujiang Zhang Fei Deng 2018Virologica Sinica2018,33,1:8
9The directional migration and differentiation of mesenchymal stem cells toward vascular endothelial cells stimulated by biphasic calcium phosphate ceramic显示文摘Osteoinductivity of porous calcium phosphate(CaP)ceramics has been widely investigated and confirmed,and it might be attributed to the rapid formation of the vascular networks after in vivo implantation of the ceramics.In this study,to explore the vascularization mechanism within the CaP ceramics,the migration and differentiation of bone marrow-derived mesenchymal stem cells(BMSCs)under the stimulation of porous biphasic calcium phosphate(BCP)ceramic with excellent osteoinductivity were systematically investigated.The results indicated that the directional migration of BMSCs toward BCP ceramic occurred when evaluated by using a transwell model,and the BMSCs migration was enhanced by the seeded macrophages on the ceramic in advance.Besides,by directly culturing BMSCs on BCP ceramic discs under both in vitro and in vivo physiological environment,it was found that the differentiation of BMSCs toward vascular endothelial cells(VECs)happened under the stimulation of BCP ceramic,as was confirmed by the up-regulated gene expressions and protein secretions of VECs-related characteristic factors,including kinase insert domain receptor,von willebrand factor,vascular cell adhesion molecule-1 and cadherin 5 in the BMSCs.This study offered a possibility for explaining the origin of VECs during the rapid vascularization process after in vivo implantation of porous CaP ceramics and could give some useful guidance to reveal the vascularization mechanism of the ceramics.Ying Chen Jing Wang Xiangdong Zhu Xuening Chen Xiao Yang Kai Zhang Yujiang Fan Xingdong Zhang 2018Regenerative Biomaterials2018,5,3:8
10Oral health in China: from vision to action显示文摘Chinese president Xi Jinping made clear at the National Health and Wellness Conference that health is the prerequisite for people's all-around development and a precondition for the sustainable development of China. Oral health is an indispensable component of overall health in humans. However, the long neglect of oral health in overall health agendas has made oral diseases an increasing concern. With this perspective, we described the global challenges of oral diseases, with an emphasis on the challenges faced by China. We also described and analyzed the recently released health policies of the Chinese government, which aim to guide midterm and long-term oral health promotion in China. More importantly, we called for specific actions to fulfill the larger goal of oral health for the nation. The implementation of primordial prevention efforts against oral diseases, the integration of oral health into the promotion of overall health, and the management of oral diseases in conjunction with other chronic non-communicable diseases with shared risk factors were highly recommended. In addition, we suggested the reform of standard clinical residency training, the development of domestic manufacturing of dental equipment and materials, the revitalization traditional Chinese medicine for the prevention and treatment of oral diseases, and integration of oral health promotion into the Belt and Road Initiative. We look forward to seeing a joint effort from all aspects of the society to fulfill the goal of Healthy China 2030 and ensure the oral health of the nation.Xuedong Zhou Xin Xu Jiyao Li Deyu Hu Tao Hu Wei Yin Yujiang Fan Xingdong Zhang 2018International Journal of Oral Science2018,10,1:7
11Light-controlled synthesis of uniform platinum nano- dendrites with markedly enhanced electrocatalytic activity显示文摘我们报导一在基于锌(II ) 播种途径的 situ 快在白轻照耀下面的卟啉(ZnP ) ,与悦耳的尺寸导致一致的球形的铂 nanodendrites。铂 nanodendrites 展览显著地与商业铂黑色相比向氧减小反应(ORR ) 和甲醇氧化反应(粗腐殖质) 改进了 electrocatalytic 活动。Weifeng Si Jia Li Huanqiao Li Shushuang Li Jie Yin Huan Xu Xinwen Guo Tao, Zhang Yujiang Song 2013Nano Research2013,6,10:7
12Matrix porosity calculation in volcanic and dolomite reservoirs and its application显示文摘矩阵孔计算断裂并且 vuggy 水库例如 volcanics 和捱过的白云石,是着急地需要在记载得好的评估解决的问题之一。在这篇论文,我们首先比较为从有矩阵孔公式的完整的直径流纹岩核心实验的孔计算的一个实验公式通常使用了。我们讨论实验公式的适用性在断裂并且 vuggy 水库,例如中介基本的 volcanics 和捱过的白云石。基于核心分析数据,我们的实验公式的计算的孔的错误分发和在这些水库的公式被给的另外的孔。统计错误分析显示我们的实验公式比另外的孔公式提供更高的精确。当孔在 1.5% 和 15% 之间时,声学的实验公式能不仅为酸的 volcanics 而且在折断的其它和 vuggy 水库被使用,例如中介基本的 volcanics 并且捱过白云石。而且,公式能在孔计算上减少地上凿穿增大和岩石改变的效果。Li Ning Wu Hongliang Feng Qingfu Wang Kewen Shi Yujiang Li Qingfeng Luo Xinping 2009Applied Geophysics2009,6,3:6
13Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts显示文摘Multiple regulatory mechanisms control osteoblast differentiation and function to ensure unperturbed skeletal formation and remodeling. In this study we identify histone lysine-specific demethylase 1(LSD1/KDM1 A) as a key epigenetic regulator of osteoblast differentiation. Knockdown of LSD1 promoted osteoblast differentiation of human mesenchymal stem cells(hMSCs)in vitro and mice lacking LSD1 in mesenchymal cells displayed increased bone mass secondary to accelerated osteoblast differentiation. Mechanistic in vitro studies revealed that LSD1 epigenetically regulates the expression of WNT7 B and BMP2. LSD1 deficiency resulted in increased BMP2 and WNT7 B expression in osteoblasts and enhanced bone formation, while downregulation of WNT7 B-and BMP2-related signaling using genetic mouse model or small-molecule inhibitors attenuated bone phenotype in vivo. Furthermore, the LSD1 inhibitor tranylcypromine(TCP) could increase bone mass in mice. These data identify LSD1 as a novel regulator of osteoblast activity and suggest LSD1 inhibition as a potential therapeutic target for treatment of osteoporosis.Jun Sun Joerg Ermann Ningning Niu Guang Yan Yang Yang Yujiang Shi Weiguo Zou 2018Bone Research2018,6,3:5
14Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang,China显示文摘The Crimean-Congo hemorrhagic fever virus(CCHFV),a member of the genus Orthonairovirus and family Nairoviridae,is transmitted by ticks and causes severe hemorrhagic disease in humans.To study the epidemiology of CCHFV in different ecosystems in Xinjiang,China,a total of 58,932 ticks were collected from Tarim Basin,Junggar Basin,Tianshan Mountain,and Altai Mountain from 2014 to 2017.Hyalomma asiaticum asiaticum was the dominant tick species in Tarim and Junggar basins,whereas Dermacentor nuttalli and Hyalomma detritum were found in Tianshan Mountain and Altai Mountain,respectively.Reverse transcription-polymerase chain reaction of the CCHFV small(S)genome segment was used for the molecular detection.The CCHFV-positive percentage was 5.26%,6.85%,1.94%,and 5.56% in Tarim Basin,Junggar Basin,Tianshan Mountain,and Altai Mountain,respectively.Sequences of the S segment were used for phylogenetic analysis and the results showed that the newly identified CCHFV strains belonged to two clades.Our study confirms that H.asiaticum asiaticum is the major vector of CCHFV in desert habitats which is consistent with previous studies,and also suggests that H.detritum and D.nuttalli are emerging vectors for CCHFV in Xinjiang.Moreover,this study reports the presence of CCHFV in the mountain habitat of Xinjiang for the first time,suggesting that future surveillance of CCHFV should also include mountainous areas.Abulimiti Moming Xihong Yue Shu Shen Chenchen Chang Cheng Wang Tao Luo Yanfang Zhang Rong Guo Zhihong Hu Yujiang Zhang Fei Deng Surong Sun 2018Virologica Sinica2018,33,1:5
153D printing of calcium phosphate bioceramic with tailored biodegradation rate for skull bone tissue reconstruction显示文摘The bone regenerative scaffold with the tailored degradation rate matching with the growth rate of the new bone is essential for adolescent bone repair.To satisfy these requirement,we proposed bone tissue scaffolds with controlled degradation rate using osteoinductive materials(Ca-P bioceramics),which is expected to present a controllable biodegradation rate for patients who need bone regeneration.Physicochemical properties,porosity,compressive strength and degradation properties of the scaffolds were studied.3D printed Ca-P scaffold(3DS),gas foaming Ca-P scaffold(FS)and autogenous bone(AB)were used in vivo for personalized beagle skull defect repair.Histological results indicated that the 3DS was highly vascularized and well combined with surrounding tissues.FS showed obvious newly formed bone tissues.AB showed the best repair effect,but it was found that AB scaffolds were partially absorbed and degraded.This study indicated that the 3D printed Ca-P bioceramics with tailored biodegradation rate is a promising candidate for personalized skull bone tissue reconstruction.Boqing Zhang Huan Sun Lina Wu Liang Ma Fei Xing Qingquan Kong Yujiang Fan Changchun Zhou Xingdong Zhang 2019Bio-Design and Manufacturing2019,2,3:5
16A new strain of Crimean-Congo hemorrhagic fever virus isolated from Xinjiang, China显示文摘Crimean-Congo hemorrhagic fever virus(CCHFV) is a highly pathogenic tick-borne virus with a fatality rate of up to 50% in humans. CCHFV is widely distributed in countries around the world.Outbreaks of CCHFV infection in humans have occurred in prior years in Xinjiang Province, China.Epidemiological surveys have detected CCHFV RNA in ticks and animals; however, few isolates were identified. In this study, we identified and isolated a new CCHFV strain from Hyalomma asiaticum asiaticum ticks collected from north of Tarim Basin in Xinjiang, China. A preliminary investigation of infection and antigens expression of CCHFV was performed in newborn mice. The target tissues for CCHFV replication in newborn mice were identified. The analysis of the phylogenetic relationships with other Chinese strains suggested that diverse genotypes of CCHFV have circulated in Xinjiang for years. These findings provide important insights into our understanding of CCHFV infection and evolution as well as disease prevention and control for local residents.Rong Guo Shu Shen Yanfang Zhang Junming Shi Zhengyuan Su Dan Liu Jinliang Liu Juan Yang Qiguo Wang Zhihong Hu Yujiang Zhang Fei Deng 2017Virologica Sinica2017,32,1:5
17Fluid Property Discrimination in Dolostone Reservoirs Using Well Logs显示文摘The Ordovician Majiagou Formation is one of the main gas-producing strata in the Ordos Basin,China.The identification of hydrocarbon-bearing intervals via conventional well logs is a challenging task.This study describes the litholog of Ma 5(Member 5 of Majiagou Formation)dolostones,and then analyzes the responses of various conventional well logs to the presences of natural gas.The lithology of the gas bearing layers is dominantly of the dolomicrite to fine to medium crystalline dolomite.Natural gas can be produced from the low resistivity layers,and the dry layers are characterized by high resistivities.Neutron-density crossovers are not sensitive to the presences of natural gas.In addition,there are no significant increases in sonic transit times in natural gas bearing layers.NMR(nuclear magnetic resonance)logs,DSI(Dipole Sonic Imager)logs and borehole image logs(XRMI)are introduced to discriminate the fluid property in Majiagou dolostone reservoirs.The gas bearing intervals have broad NMR T2(transverse relaxation time)spectrum with tail distributions as well as large T2gm(T2 logarithmic mean values)values,and the T2 spectrum commonly display polymodal behaviors.In contrast,the dry layers and water layers have low T2gm values and very narrow T2 spectrum without tails.The gas bearing layers are characterized by low Vp/Vs ratios,low Poisson’s ratios and low P-wave impedances,therefore the fluid property can be discriminated using DSI logs,and the interpretation results show good matches with the gas test data.The apparent formation water resistivity(AFWR)spectrum can be derived from XRMI image logs by using the Archie’s formula in the flushed zone.The gas bearing layers have broad apparent formation water resistivity spectrum and tail distributions compared with the dry and water layers,and also the interpretation results from the image logs exhibit good agreement with the gas test data.The fluid property in Majiagou dolostone reservoirs can be discriminated through NMR logs,DSI logs and borehole image logs.This study helps establish a predictable model for fluid property in dolostones,and have implications in dolostone reservoirs with similar geological backgrounds worldwide.WANG Guiwen LAI Jin LIU Bingchang FAN Zhuoying LIU Shichen SHI Yujiang ZHANG Haitao CHEN Jing 2020Acta Geologica Sinica(English Edition)2020,94,3:4
18M CrAlY/TaC Metal Matrix Composite Coatings Produced by Electrospark Deposition显示文摘M CrAlY/TaC metal matrix composite coatings with 10, 20 and 30 wt.% TaC have been successfully produced by electrospark deposition (ESD). The effects of TaC content on microstructure, hardness and oxidation behavior of the composite coatings were studied. The results showed that the composite coatings were composed of superfine γ columnar dendrite and large TaC particles dispersedly distributed. The hardness was enhanced but oxidation resistance of the composite coatings was reduced with increasing TaC contents.Yujiang XIE Yanhong YANG Mingsheng WANG Jian HOU 2013Acta Metallurgica Sinica(English Letters)2013,26,2:4
19BMSCs-assisted injectable Col I hydrogel-regenerated cartilage defect by reconstructing superficial and calcified cartilage显示文摘The self-healing capacity of cartilage was limited due to absence of vascular,nervous and lymphatic systems.Although many clinical treatments have been used in cartilage defect repair and shown a promising repair result in short term,however,regeneration of complete zonal structure with physiological function,reconstruction cartilage homeostasis and maintaining long-term repair was still an unbridgeable chasm.Cartilage has complex zonal structure and multiple physiological functions,especially,superficial and calcified cartilage played an important role in keeping homeostasis.To address this hurdle of regenerating superficial and calcified cartilage,injectable tissue-induced type I collagen(Col I)hydrogel-encapsulated BMSCs was chosen to repair cartilage damage.After 1 month implantation,the results demonstrated that Col I gel was able to induce BMSCs differentiation into chondrocytes,and formed hyaline-like cartilage and the superficial layer with lubrication function.After 3 months post-surgery,chondrocytes at the bottom of the cartilage layer would undergo hypertrophy and promote the regeneration of calcified cartilage.Six months later,a continuous anatomical tidemark and complete calcified interface were restored.The regeneration of neo-hyaline cartilage was similar with adjacent normal tissue on the thickness of the cartilage,matrix secretion,collagen type and arrangement.Complete multilayer zonal structure with physiological function remodeling indicated that BMSCs-assisted injectable Col I hydrogel could reconstruct cartilage homeostasis and maintain long-term therapeutic effect.Hanxu Cai PeileiWang Yang Xu Ya Yao Jia Liu Tao Li Yong Sun Jie Liang Yujiang Fan Xingdong Zhang 2020Regenerative Biomaterials2020,7,1:4
20Ag_(2)Se Complex Nanostructures with Photocatalytic Activity and Superhydrophobicity显示文摘Single-crystalline Ag_(2)Se complex nanostructures have been synthesized via a solvothermal route in which selenophene(C4H4Se)as a selenylation source reacts with AgNO3 at a temperature of 240°C.An orthorhombic phaseβ-Ag_(2)Se nanostructure was identified by X-ray diffraction(XRD),Raman spectroscopy,field emission scanning electron microscopy(FE-SEM),high resolution transmission electron microscopy(HRTEM),and photoluminescence(PL)spectroscopy.The wettability of the as-synthesizedβ-Ag_(2)Se nanostructure was studied by measurement of the water contact angle(CA).Static water CA values of over 150°were obtained,which can be attributed to theβ-Ag_(2)Se complex nanostructure having a combination of micro-and nanostructures.The superhydrophobic Ag_(2)Se nanostructure may find applications in self-cleaning.Additionally,the photocatalytic activity of the as-synthesizedβ-Ag_(2)Se nanostructure was evaluated by photodegradation of rhodamine B(RhB)dye under ultraviolet(UV)light irradiation.Huaqiang Cao Yujiang Xiao Yuexiang Lu Jiefu Yin Baojun Li Shuisheng Wu Xiaoming Wu 2010Nano Research2010,3,12:4
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