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| 1 | Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis显示文摘 | Nicholson DW Ali A Thornberry NA | | 0，，： | 4 |
| 2 | Barrett’s metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor显示文摘 | Anna M Nicholson Trevor A Graham Ashley Simpson Adam Humphries Nicola Burch Manuel Rodriguez-Justo Marco Novelli Rebecca Harrison Nicholas A Wright Stuart A C McDonald Janusz A Jankowski | 2012 | Gut2012，，10： | 3 |
| 3 | Transanal total mesorectal excision:a valid option for rectal cancer?显示文摘Low anterior resection can be a challenging operation, especially in obese male patients and in particular after radiotherapy. Transanal total mesorectal excision(Ta TME) might offer technical advantages over laparoscopic or open approaches particularly for tumors in the distal third of the rectum. The aim of this article is to review the current experience with Ta TME. The limits and future developments are also explored. Although the experience with Ta TME is still limited, it might be a promising alternative to laparoscopic TME, especially for difficult cases where laparoscopy is too demanding. The preliminary data on complications and short-term oncological outcomes are good, but also emphasize the importance of careful patient selection. Finally, there is a need for large-scale trials focusing on long-term outcomes and oncological safety before widespread adoption can be recommended. | Nicolas C Buchs Gary A Nicholson Frederic Ris Neil J Mortensen Roel Hompes | 2015 | World Journal of Gastroenterology2015，21，41： | 3 |
| 4 | 1400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor显示文摘AIM: To investigate the effects of 1400W-a selective inducible nitric oxide synthase(iN OS) inhibitor in a model of donation after circulatory death(DCD) kidneys. METHODS: Porcine kidneys were retrieved after 25 min warm ischemia. They were then stored on ice for 18 h before being reperfused ex vivo with oxygenated autologous blood on an isolated organ perfusion system. The selective i NOS inhibitor 1400W(10 mg/kg) was administered before reperfusion(n = 6) vs control group(n = 7). Creatinine(1000 μmol/L) was added to the system, renal and tubular cell function and the level of ischemia reperfusion injury were assessed over 3 h of reperfusion using plasma, urine and tissue samples. RESULTS: Kidneys treated with 1400 W had a higher level of creatinine clearance(CrC l) [area under the curve(AUC) CrC l: 2.37 ± 0.97 mL /min per 100 g vs 0.96 ± 0.32 mL /min per 100 g, P = 0.004] and urine output [Total: 320 ± 96 mL vs 156 ± 82 mL, P = 0.008]. There was no significant difference in levels of fractional excretion of sodium(AUC, Fr ex Na+: Control, 186.3% ± 81.7%.h vs 1400 W, 153.4% ± 12.1%.h, P = 0.429). Levels of total protein creatinine ratio were significantly lower in the 1400 W group after 1 h of reperfusion(1h Pr/Cr: 1400 W 9068 ± 6910 mg/L/mmol/L vs Control 21586 ± 5464 mg/L/mmol/L, P = 0.026). Levels of 8-isoprostane were significantly lower in the 1400 W group [8-iso/creatinine ratio: Control 239 ± 136 pg/L/mmol/L vs 1400 W 139 ± 47 pg/L/mmol/L, P = 0.041].CONCLUSION: This study demonstrated that 1400 W reduced ischaemia reperfusion injury in this porcine kidney model of DCD donor. Kidneys had improved renal function and reduced oxidative stress. | Sarah A Hosgood Phillip J Yates Michael L Nicholson | 2014 | World Journal of Transplantation2014，4，4： | 2 |
| 5 | RF impedance of power lines and line impedance stabilization networks in conducted interference measurements 显示文摘 | Nicholson J R Malack A | 1973 | IEEE Transactions on Electromagnetic Compatibility1973，25，1： | 2 |
| 6 | Human ICE/CED-3 Protease Nomenclature显示文摘 | Emad S Alnemri David J Livingston Donald W Nicholson Guy Salvesen Nancy A Thornberry Winnie W Wong Junying Yuan | 1996 | Cell1996，，2： | 2 |
| 7 | Dairy products and breast cancer: the IGF- Ⅰ , estrogen, and bGH hypothesis 显示文摘 | Nicholson A Barnard N | 1997 | Medical Hypothesis1997，48，6： | 1 |
| 8 | Finding the shortest route between two points in a network显示文摘 | Nicholson T A J | 1966 | The Computer Journal1966，，3： | 1 |
| 9 | Boosting immunity to influenza H5N1 with MF 59-adjuvanted H5N3 A/ Duck/Singapore/97 vaccine in a primed human population显示文摘 | Stephenson I Nicholson KG Colegate A | 2003 | Vaccine2003，21，15： | 1 |
| 10 | Effect of fluid flow characteristics on nozzle blockage in aluminium- killed steels显示文摘 | Wilson F G Heesom M J Nicholson A | 1987 | Ironmaking and Steelmaking1987，14，6： | 1 |
| 11 | An Inventory of Heavy Metals Inputs to Agricultural Soils in England and Wales显示文摘 | Nicholson F A Smith S R Alloway B J | 2003 | The Science of the Total Environment2003，311，： | 1 |
| 12 | Identification and inhibition of the ICE/Ced-3 protease necessary for mammalian apoptosis显示文摘 | Nicholson DW Ali A Thornb erry NA | 1995 | Nature1995，376，6535： | 1 |
| 13 | Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis 显示文摘 | Nicholson D W Alia Thornberry N A | 1995 | Nature1995，376，6535： | 1 |
| 14 | Solitary pulmonary papillomas in Adults:a clinicopathologic an in situ hybridization study of 14 cases combined with 27 cases in the literature显示文摘 | Flieder D B Koss M N Nicholson A | 1998 | Am J Surg Pathol1998，22，11： | 1 |
| 15 | Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis显示文摘 | AIi A Thornberry NA | 1995 | Nature1995，376，： | 1 |
| 16 | Anastomoses of the ovarian and uterine arteries:a potential pitfall and cause of failure of uterine embolization显示文摘 | Matson M Nicholson A Belli AM | 2000 | Cardiovasc Intervent Radiol2000，23，5： | 1 |
| 17 | Distribution of EGF and its receptor in growing red deer antler显示文摘 | Barling P M Lai A K Nicholson L F | 2005 | Cell Biol Int2005，29，3： | 1 |
| 18 | Observations of Col- letotrichum graminicola on sweet corn in Indiana 显示文摘 | Warren H Nicholson R Ullstrup A Sharvelle E | 1973 | Plant Disease Re- port1973，，57： | 1 |
| 19 | The first low molecular weight antibiotic from Lactic acid bacteria: reutericyclin, a new tetramic acid 显示文摘 | H?ltzel A G?nzle M G Nicholson G J | 2000 | Angewandte Chemie International Edition2000，39，： | 1 |
| 20 | Ribosomal DNA analysis for resolution of genotypic classes of Pleurotus显示文摘 | Bunyard B A Chaichuchote S Nicholson M S | 1996 | Mycol Res1996，100，2： | 1 |
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