|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 西藏羊八井热田地热流体成因及演化的惰性气体制约显示文摘地热流体中惰性气体的相对丰度和同位素组成 ,不仅可以揭露热田的热源性质 ,而且还能够揭示深、浅层地热流体的内在联系和演化过程等。在西藏羊八井热田的地热气体中 ,已检测出大量的 4 He组分 ,3He/ 4 He值是大气的 0 .0 87~ 0 .2 5 9倍 ,表明深部地壳物质的局部熔融为热田提供能量。浅层地热流体的 3He/ 4 He值自西北向东南呈降低趋势 ,与热储温度的变化相一致 ,反映出侧向运移时补充了更多的壳源氦。热田北区深层地热流体具有稍高的 3He/ 4 He值 ,是浅层地热流体的母源。气体中氪和氙的相对丰度具有大气降水成因的特征。结合现有的实际资料 。 | 赵平 Mack KENNEDY 多吉 谢鄂军 杜少平 David SHUSTER 金建 | 2001 | 岩石学报2001，17，3： | 24 |
| 2 | Rho A signaling and blood pressure: The consequence of failing to “Tone it Down”显示文摘Uncontrolled high blood pressure is a major risk factor for heart attack, stroke, and kidney failure and contributes to an estimated 25% of deaths worldwide. Despite numerous treatment options, estimates project that reasonable blood pressure(BP) control is achieved in only about half of hypertensive patients. Improvements in the detection and management of hypertension will undoubtedly be accomplished through a better understanding of the complex etiology of this disease and a more comprehensive inventory of the genes and genetic variants that influence BP regulation. Recent studies(primarily in pre-clinical models) indicate that the small GTPase Rho A and its downstream target, Rho kinase, play an important role in regulating BP homeostasis. Herein, we summarize the underlying mechanisms and highlight signaling pathways and regulators that impart tight spatial-temporal control of Rho A activity. We also discuss known allelic variations in the Rho A pathway and consider how these polymorphisms may affect genetic risk for hypertension and its clinical manifestations. Finally, we summarize the current(albeit limited) clinical data on the efficacy of targeting the Rho A pathway in hypertensive patients. | Xue Bai Rachel Dee Kevin D Mangum Christopher P Mack Joan M Taylor | 2016 | World Journal of Hypertension2016，6，1： | 3 |
| 3 | 前列腺癌:近期研究结果和新方向显示文摘虽然对临床局限性前列腺癌的最佳治疗手段尚未有定论,但针对不同患者应给予个体化治疗是目前前列腺癌临床治疗中的一致目标。近10年对前列腺癌的不断研究,临床上对前列腺癌的预防与早期诊断,以及依据治疗前各项实验室与影响学检查结果,对患者选择性地给予“等待观察”或积极治疗已取得了相当成就。本文就近10年来前列腺癌研究中一些最重要的研究结果与可能具显著发展前景的领域作一综述。 | Mack Roach Ⅲ 孔琳 | 2007 | 中国癌症杂志2007，17，3： | 3 |
| 4 | NASPGHAN Practice Guidelines: Diagnosis and Management of Hepatitis C Infection in Infants, Children, and Adolescents显示文摘 | Cara L. Mack Regino P. Gonzalez-Peralta Nitika Gupta Daniel Leung Michael R. Narkewicz Eve A. Roberts Philip Rosenthal Kathleen B. Schwarz | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，6： | 2 |
| 5 | Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart显示文摘 | Mack CA Patel SR Schwarz EA | | 0，，： | 2 |
| 6 | BRAF and KRAS Mutations in Hyperplastic Polyps and Serrated Adenomas of the Colorectum: Relationship to Histology and CpG Island Methylation Status显示文摘 | Shi Yang Francis A Farraye Charline Mack Oksana Posnik Michael J O’Brien | 2004 | The American Journal of Surgical Pathology2004，，11： | 2 |
| 7 | Chronic developmental lead exposure increases the threshold for long-term potentiation in rat dentate gyrus in vivo 显示文摘 | Gilbert ME Mack CM Lasley SM | 1996 | Brain Res1996，736，12： | 2 |
| 8 | Data mining for power system security assessment--a large scale study显示文摘 | Wehenkel Louis Mack Philippe | 2002 | IEEE Power Engineering Society Winter Meeting2002，1，1： | 2 |
| 9 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 10 | 前列腺癌:近期研究结果和新方向显示文摘目前美国肿瘤学界对临床局限性前列腺癌的最佳治疗手段仍存在争议。然而,近10年对前列腺癌的不断研究,在前列腺癌的预防与早期诊断,以及对部分患者选择“等待观察”或积极治疗等方面取得了重要进展。在大量临床研究的基础上所取得并确定的具研究发展潜力的相关领域,也有助于我们更好地理解如何对临床局限性前列腺癌进行更准确的分期及采取更个体化的治疗。 | Mack Roach Ⅲ 孔琳 | 2007 | 继续医学教育2007，21，6： | 2 |
| 11 | 利用补充真实世界数据研究获得更深层次的认识显示文摘随着患者、医护人员、药品注册人员和政策决定者对现实世界中各种诊疗手段的安全性和有效性相关证据的迫切需求,我们需要新的研究设计来高效有效地对此类问题进行评估。与此同时,越来越多的二手数据可以用来提供此种相关证据,常用的二手数据包括电子医疗档案和医疗保险数据等。补充真实世界数据研究同时利用了现有二手数据和通过医生/患者收集的一手数据,并将两者进行结合。在现有数据的基础上,补充真实世界数据研究可以集中精力收集缺失的重要信息来满足研究目的。本文将对补充真实世界数据研究进行介绍,包括研究设计要素,研究的优点和局限性,实施要点以及应用实例等。 | CD Mack L Parmenter E Brinkley L Liu NA Dreyer | 2016 | 药物流行病学杂志2016，25，1： | 2 |
| 12 | A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer显示文摘 | Ramesh K. Ramanathan Chandra P. Belani Deepti A. Singh Michael Tanaka Heinz-Josef Lenz Yun Yen Hedy L. Kindler Syma Iqbal Jeff Longmate Philip C. Mack Georg Lurje Regina Gandour-Edwards Janet Dancey David R. Gandara | 2009 | Cancer Chemotherapy and Pharmacology2009，，4： | 2 |
| 13 | Capacitive deionization of NH 4 ClO 4 solutions with carbon aerogel electrodes显示文摘 | J. C. Farmer D. V. Fix G. V. Mack R. W. Pekala J. F. Poco | 1993 | Journal of Applied Electrochemistry1993，，10： | 2 |
| 14 | 水合作用与身体活动:科学概念及实际应用显示文摘 | Gary W Mack Ph.D. Michael F.Bergeron | 2001 | 体育科学2001，21，3： | 2 |
| 15 | Increased Immune Reactivity Predicts Aggressive Complicating Crohn’s Disease in Children显示文摘 | Marla C. Dubinsky Subra Kugathasan Ling Mei Yoana Picornell Justin Nebel Iwona Wrobel Antonio Quiros Gary Silber Ghassan Wahbeh Lirona Katzir Eric Vasiliauskas Ron Bahar Anthony Otley David Mack Jonathan Evans Joel Rosh Maria Oliva Hemker Neal Leleiko Wal | 2008 | Clinical Gastroenterology and Hepatology2008，，10： | 2 |
| 16 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 17 | Trauma-induced alterations in macrophage function显示文摘 | Mc Carler M D Mack V E Daly T M | 1998 | Surgery1998，123，： | 2 |
| 18 | Continuing professional development:progress beyond continuing medical education显示文摘Continuing medical education(CME)is rapidly evolving into competency-based continuing professional development(CPD)and this is driving change in self-directed CPD programs undertaken by individual practitioners as well as CPD programs or frameworks offered by CPD educators.This progression is being led by many factors including the rapid change in medical knowledge and medical practitioners along with changes in patients and society,healthcare systems,regulators and the political environment.We describe our experiences primarily concerning low-resource environments,in creating the International Council of Ophthalmology(ICO)Guide to Effective CPD/CME and in developing a CPD program for the Cambodian Ophthalmological Society(COS)twinned with the Royal Australian and New Zealand College of Ophthalmologists(RANZCO).At the conclusion of the project,47(100%)Cambodian practicing ophthalmologists were registered in the CPD program and 21(45%)were actively participating in the online COS-CPD program recording.We discuss challenges in CPD,propose solutions to overcome them and recommend developing research in CPD as needed to effectively enhance educational activities with impact in public health. | Helena Prior Filipe Heather Gwen Mack Karl C.Golnik | 2017 | Annals of Eye Science2017，，1： | 2 |
| 19 | High performance plasmonic crystal sensor formed by soft nanoimprint lithography 显示文摘 | Malyarchuk V Hua F Mack N H | 2005 | Optics express2005，13，15： | 1 |
| 20 | Moleeular mechanisms of Staphylococcus epidermidis biofilm formation显示文摘 | Mack D | 1999 | J Hosp Infect1999，43，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员