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| 1 | Electroacupuncture improves gut barrier dysfunction in prolonged hemorrhagic shock rats through vagus anti-inflammatory mechanism显示文摘AIM:To investigate whether electroacupuncture(EA)at Zusanli(ST36)prevents intestinal barrier and remote organ dysfunction following prolonged hemorrhagic shock through a vagus anti-inflammatory mechanism.METHODS:Sprague-Dawley rats were subjected to about 45%of total blood volume loss followed by delayed fluid replacement(DFR)with Ringer lactate 3h after hemorrhage.In a first study,rats were randomly divided into six groups:(1)EAN:EA at non-channel acupoints followed by DFR;(2)EA:EA at ST36 after hemorrhage followed by DFR;(3)VGX/EA:vagotomy(VGX)before EA at ST36 and DFR;(4)VGX/EAN:VGX before EAN and DFR;(5)α-bungarotoxin(α-BGT)/EA:intraperitoneal injection ofα-BGT before hemorrhage,followed by EA at ST36 and DFR;and(6)α-BGT/EAN group:α-BGT injection before hemorrhage followed by EAN and DFR.Survival and mean arterial pressure(MAP)were monitored over the next 12 h.In a second study,with the same grouping and treatment,cytokine levels in plasma and intestine,organ parameters,gut injury score,gut permeability to 4 kDa FITC-dextran,and expression and distribution of tight junction protein ZO-1 were evaluated.RESULTS:MAP was significantly lowered after blood loss;EA at ST36 improved the blood pressure at corresponding time points 3 and 12 h after hemorrhage.EA at ST36 reduced tumor necrosis factor-αand interleukin(IL)-6 levels in both plasma and intestine homogenates after blood loss and DFR,while vagotomy or intraperitoneal injection ofα-BGT before EA at ST36reversed its anti-inflammatory effects,and EA at ST36did not influence IL-10 levels in plasma and intestine.EA at ST36 alleviated the injury of intestinal villus,the gut injury score being significantly lower than that of EAN group(1.85±0.33 vs 3.78±0.59,P<0.05).EA at ST36 decreased intestinal permeability to FITCdextran compared with EAN group(856.95 ng/mL±90.65 ng/mL vs 2305.62 ng/mL±278.32 ng/mL,P<0.05).EA at ST36 significantly preserved ZO-1 protein expression and localization at 12 h after hemorrhage.However,EA at non-channel acupoints had no such effect,and abdominal vagotomy andα-BGT treatment could weaken or eliminate the effects of EA at ST36.Besides,EA at ST36 decreased blood aminotransferase,MB isoenzyme of creatine kinase and creatinine vs EAN group at corresponding time points.At the end of 12-h experiment,the survival rate of the EA group was significantly higher than that of the other groups.CONCLUSION:EA at ST36 attenuates the systemic inflammatory response,protects intestinal barrier integrity,improves organ function and survival rate after hemorrhagic shock via activating the cholinergic antiinflammatory mechanism. | Ming-Hua Du Hong-Min Luo Sen Hu Yi Lv Zhi-Long Lin Li Ma | 2013 | World Journal of Gastroenterology2013，19，36： | 21 |
| 2 | Incidence of infectious complications is associated with a high mortality in patients with hepatitis B virus-related acute-on-chronic liver failure显示文摘BACKGROUND In China,hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is the most common liver failure characterized by serious clinical syndromes of liver decompensation with a very high mortality.Bacterial and/or fungal infections are the most common complications that are associated with high short-term mortality.Bacterial translocation from the intestine,impaired hepatic clearance,and immune paralysis of circulating immune cells are thought to contribute to infectious complications in liver failure.The control of bacterial and fungal infections is the key to improving HBV-ACLF outcomes.Active prevention,early diagnosis,and timely treatment of bacterial and fungal infections are essential for treating HBV-ACLF.AIM To investigate the frequency and role of bacterial and fungal infections in patients with HBV-ACLF.METHODS Patients with HBV-ACLF hospitalized at Taihe Hospital,Hubei University of Medicine from January 2014 to December 2017 were retrospectively enrolled.Patient-related information was retrieved from the hospital case database,including general information,blood biochemistry,complications,etc.According to the occurrence of secondary infection or not,the patients were divided into an infection group and a non-infection group.The sites,types,and incidences of bacterial and fungal infections and the influence of infections on the prognosis of HBV-ACLF were statistically analyzed.The risk factors for infections were assessed by unconditional logistic regression.RESULTS There were 174 cases of HBV-ACLF that met the enrollment criteria,of which 114 (65.52%) were diagnosed with infectious complications.Infections occurred in the abdominal cavity (87 cases),respiratory tract (51 cases),urinary tract (18 cases),and biliary tract (10 cases).Patients with infectious complications had a significantly higher 28-d mortality (70.18%,80/114) than those without (40.00%,24/60)(70.18% vs 40.00%,P < 0.05).And patients with infectious complications had a much higher incidence of non-infectious complications (54.39%,62/114)(54.39% vs 15.00%,P < 0.05),leading to an extremely high 28-d mortality of 88.71%(55/62)(P < 0.05).The grade of liver failure,period of hospital stay ≥ 30 d,age ≥ 45 years,and percentage of neutrophils > 70% were identified as risk factors for infectious complications.CONCLUSION The high incidence of infectious complications in patients with HBV-ACLF is associated with severity and deterioration of the disease and may contribute to the extremely high mortality of these patients. | Chen Wang De-Qiang Ma Sen Luo Chuan-Min Wang De-Ping Ding You-You Tian Kang-Jian Ao Yin-Hua Zhang Yue Chen Zhong-Ji Meng | 2019 | World Journal of Clinical Cases2019，7，16： | 18 |
| 3 | Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway显示文摘Stroke is an acute cerebrovascular disease caused by ruptured or blocked blood vessels.For the prevention of ischemic stroke,the coagulation state of blood and cerebrovascular protection should be considered.Our previous study has shown that salvianolic acid A(SAA),which is a water-soluble component from the root of Salvia Miltiorrhiza Bge,prevents thrombosis with a mild inhibitory effect on platelet aggregation.In this study we investigated the preventive effects of SAA on cerebrovascular endothelial injury caused by ischemia in vivo and oxygen-glucose deprivation(OGD)in vitro,and explored the underlying mechanisms.An autologous thrombus stroke model was established in SD rats by electrocoagulation.SAA(10 mg/kg)was orally administered twice a day for 5 days before the operation.The rats were sacrificed at 24 h after the operation.We showed that pretreatment with SAA significantly improved the neurological deficits,intracerebral hemorrhage,BBB disruption,and vascular endothelial dysfunction as compared with model group.In human brain microvascular endothelial cells(HBMECs),pretreatment with SAA(10μM)significantly inhibited OGD-induced cell viability reduction and degradation of tight junction proteins(ZO-1,occludin,claudin-5).Furthermore,we found that SAA inhibited the upregulation of Src signaling pathway in vivo and vitro and reversed the increased expression of matrix metalloproteinases(MMPs)after ischemic stroke.In conclusion,our results suggest that SAA protects cerebrovascular endothelial cells against ischemia and OGD injury via suppressing Src signaling pathway.These findings show that pretreatment with SAA is a potential therapeutic strategy for the prevention of ischemic stroke. | Cheng-di Liu Nan-nan Liu Sen Zhang Guo-dong Ma Hai-guang Yang Ling-lei Kong Guan-hua Du | 2021 | Acta Pharmacologica Sinica2021，42，3： | 15 |
| 4 | Quality deterioration and improvement of wheat gluten protein in frozen dough显示文摘Frozen dough technology can effectively recover sensory quality of frozen flour products.This technique has gradually drawn the research interest in the industrialization of staple food.However,the quality of the final frozen products remains inferior to that of fresh products.This study reviewed the deterioration of gluten network in dough caused by ice recrystallization and various additives.This study also investigated the optimization of the freezing process and other empirical improvement techniques.Suggestions for future research were also provided. | Wenjuan Feng Sen Ma Xiaoxi Wang | 2020 | Grain & Oil Science and Technology2020，3，1： | 13 |
| 5 | Study on the effect of wheat bran dietary fiber on the rheological properties of dough显示文摘The aim of the study was to determine the influence of wheat bran dietary fiber on wheat flour dough rheological properties.In this paper,wheat bran dietary fiber(WBDF)with different levels(0,3%,6%,9%,12%)were added to wheat flour and the characterization of dough rheological properties was conducted by rapid visco-analyzer,farinograph,as well as rotational rheometer.The results from pasting properties showed a gradual reduction in peak viscosity,trough viscosity,final viscosity and setback with increasing WBDF content.At high WBDF concentration,the significant increase of water absorption,formation time as well as weakening degree implied the harder formation of gluten network structure and the competition for water between gluten and WBDF particles.Such conclusion was in line with the findings from dynamic rheology tests,in which the doughs containing WBDF were more sensitive to strain regardless of their rigid and stiff texture.This study revealed vulnerable dough structure induced by WBDF,as well as the strengthened elastic property,elaborating the harmful effects ofWBDF on the rheological properties of doughs. | Ning Liu Sen Ma Li Li Xiaoxi Wang | 2019 | Grain & Oil Science and Technology2019，2，1： | 13 |
| 6 | CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys显示文摘Dear Editor,PINK1 mutations cause autosomal recessive and early-onset Parkinson’s disease(PD)with selective neurodegeneration.Unfortunately,current PINK1 knockout(KO)mouse1,2 and pig models3,4 are unable to recapitulate the selective and overt neurodegeneration seen in PD patients.Furthermore,endogenous Pink1 in the mouse brain is expressed at very low levels and can only be detected via immunoprecipitation,5 meaning that PINK1’s function in the mammalian brain needs to be assessed using larger animals that are closer to humans.We previously used CRISPR/Cas9 to target the monkey gene in one-cell stage embryos.6 Using the same approach,we designed two gRNAs to target exon 2(T1)and exon 4(T2),which encode a kinase domain in the PINK1 gene of rhesus monkeys(Fig.1a).CRISPR/Cas9 and PINK1 gRNAs were injected into one-cell stage rhesus monkey embryos.A T7E1 assay and sequencing of PCR products from the injected embryos showed high efficiency(61.5%)in targeting PINK1(Fig.1b and Supplementary information,Fig.S1).Transfer of 87 embryos to 28 surrogate rhesus monkeys resulted in 11 pregnancies(39.2%)(Fig.1b).Eleven fetuses developed to term and were born naturally.Of these live monkeys,eight carried PINK1 mutations(M),and three were wild type(WT).However,three mutant monkeys(M1,M3 and M4)were newborn triplets that struggled to survive and died 3-4 days after birth.One WT newborn monkey also died after a difficult labor.Another mutant monkey(M2)died 7 days after birth without noticeable warning signs or symptoms.The other three mutant monkeys(M6,M7 and M8)have lived for three years;M5,however,reduced its food intake and showed weakness at the age of 1.5 years,and died 30 days after anesthesia for MRI examination. | Weili Yang Yunbo Liu Zhuchi Tu Chong Xiao Sen Yan Xishan Ma Xiangyu Guo Xiusheng Chen Peng Yin Zhengyi Yang Su Yang Tianzi Jiang Shihua Li Chuan Qin Xiao-Jiang Li | 2019 | Cell Research2019，29，4： | 12 |
| 7 | Pelvic Exenteration for Recurrent and Persistent Cervical Cancer显示文摘 | Lei Li Shui-Qing Ma Xian-Jie Tan Sen Zhong Ming Wu | 2018 | Chinese Medical Journal2018，，13： | 12 |
| 8 | Comparison of screening strategies for Lynch syndrome in patients with newly diagnosed endometrial cancer:a prospective cohort study in China显示文摘Background: The prevalence of Lynch syndrome and screening strategies for this disorder in Chinese patients with endometrial cancer have seldom been investigated. Such data would be essential for the screening, prevention, genetic counseling, and treatment of Lynch syndrome. The purpose of this prospective study was to determine the accuracy of the mismatch repair (MMR) protein immunohistochemistry (IHC), microsatellite instability (MSI) test, and clinical diagnostic criteria in screening for Lynch syndrome-associated endometrial cancer (LS-EC) in a prospective Chinese cohort. Methods: All patients with newly diagnosed endometrial cancer (EC) were evaluated using clinical diagnostic criteria (Amsterdam II criteria and the revised Bethesda guidelines), MSI test, and IHC of MMR proteins in tumor tissues. For all patients, the screening results were compared with results of germline sequencing for pathogenic variants of MMR genes. Results: Between December 2017 and August 2018, a total of 111 unselected patients with newly diagnosed EC were enrolled. Six patients (5.4%) harbored a pathogenic germline mutation of MMR genes: 1 had a mutation in MutL homolog 1 (MLH1), 2 in MutS homolog 2 (MSH2), and 3 in MutS homolog 6 (MSH6). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for identifying LS-EC were 33.3%, 88.6%, 14.3%, and 95.9%, for the clinical criteria, 66.7%, 75.0%, 14.3%, and 97.3% for IHC of MMR proteins, 100%, 89.9%, 33.3%, and 100% for MSI test, and 100%, 72.4%, 20.0% and 100% for combined IHC and MSI test, respectively. The combination of IHC and MSI test had higher sensitivity and PPV than the clinical criteria (p = 0.030). MSI test and IHC were highly concordant for LS-EC screening (73/77, 94.8%). Conclusion: The accuracy of the combination of IHC of MMR proteins and MSI test for screening LS among Chinese patients with EC was superior to that of the clinical criteria. | Xiaopei Chao Lei Li Ming Wu Shuiqing Ma Xianjie Tan Sen Zhong Yalan Bi Jinghe Lang | 2019 | Cancer Communications2019，39，1： | 8 |
| 9 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 10 | Effects of insoluble dietary fiber from wheat bran on noodle quality显示文摘Benefiting from its favorable effects in promoting intestinal peristalsis,increasing satiety and reducing postprandial blood sugar,wheat bran insoluble dietary fiber(IDF)could be added to noodles to improve the nutrition value of noodle products.However,the addition of IDF usually results in an adverse effect on the quality characteristics of fiber fortified products,leading to unfavorable texture and consumption drop.It was found that IDF could weaken dough characteristics,thereby causing the quality deterioration of noodles,but the mechanism is unclear as yet.This study aimed to investigate the effects of different amounts of IDF on the texture quality and cooking quality of noodles.The water distribution,rheological properties,pasting properties and cooking properties of the noodles were determined by low-field nuclear magnetic resonance(LF-NMR),dynamic rheometer,and rapid visco-analyzer.The results of the LF-NMR showed that the increased IDF in the noodles resulted in a contraction of relaxation time and an increase in the proportion of loosely bound water.At a high amount of IDF,the water absorption and tensile distance of the noodles significantly decreased and the cooking loss rate increased,with a downward trend in peak viscosity,final viscosity and setback values.Moreover,IDF could improve the storage modulus and loss modulus of sheeted dough and enhance the texture of noodles.Furthermore,the correlations between IDF addition amounts and rheological properties as well as cooking properties were analyzed,and the results confirmed that noodles with the IDF amount of 2%–4%had higher nutrition and quality.This study provides the basis for future development and improvement of IDF-enriched health foods. | Mengxu Lei Jihong Huang Xiaoling Tian Peng Zhou Qi Zhu Limin Li Li Li Sen Ma Xiaoxi Wang | 2021 | Grain & Oil Science and Technology2021，4，1： | 8 |
| 11 | Characteristics of volatile compounds removal in biogas slurry of pig manure by ozone oxidation and organic solvents extraction显示文摘Biogas slurry is not suitable for liquid fertilizer due to its high amounts of volatile materials being of complicated composition and peculiar smell. In order to remove volatiles from biogas slurry efficiently, the dynamic headspace and gas chromatography-mass spectrometry were used to clear the composition of volatiles. Nitrogen stripping and superfluous ozone were also used to remove volatiles from biogas slurry. The results showed that there were 21 kinds of volatile compounds in the biogas slurry, including sulfur compounds, organic amines, benzene, halogen generation of hydrocarbons and alkanes, some of which had strong peculiar smell. The volatile compounds in biogas slurry can be removed with the rate of 53.0% by nitrogen stripping and with rate of 81.7% by the oxidization and stripping of the superfluous ozone. On this basis, the removal rate of the volatile compounds reached 99.2% by chloroform and n-hexane extraction, and almost all of odor was eliminated. The contents of some dissolved organic compounds decreased obviously and however main plant nutrients had no significant change in the biogas slurry after being treated. | Yujun Wang Lianshuang Feng Xiaosong Zhao Xiulan Ma Jingmin Yang Huiqing Liu Sen Dou Miping Zhou Zhonglei Xie | 2013 | Journal of Environmental Sciences2013，25，9： | 7 |
| 12 | Late Paleozoic to Mesozoic extension in southwestern Fujian Province, South China: Geochemical, geochronological and Hf isotopic constraints from basic-intermediate dykes显示文摘The tectonic evolution of SE China block since late Paleozoic remains debated.Here we present a new set of zircon U-Pb geochronological,Lu-Hf isotopic data and whole-rock geochemistry for two stages of basicintermediate dykes from the southwestern Fujian.The samples were collected from the NE-trending(mainly diabases) and NW-trending(mainly diabasic diorites) dykes and yielded zircon U-Pb ages of 315 and 141 Ma,with ε_(Hf)(t) values of-8.90 to 7.49 and-23.39 to-7.15(corresponding to T_(DM2) values of 850 to 1890 Ma and 737 to 2670 Ma),respectively.Geochemically these rocks are characterized by low TiO_2(0.91-1.73 wt.%)and MgO(3.04-7.96 wt.%),and high Al_2O_3(12.5-16.60 wt.%) and K_2O(0.60-3.63 wt.%).Further they are enriched in LREEs and ULEs(Rb,Ba,Th and K).but depleted in HFSEs(Nb,Ta and Zr).The tectonic discrimination analysis revealed that the dykes were formed in an intraplate extensional environment.However,the NW trending dykes show crust-mantle mixed composition,which indicate an extensional tectonic setting with evidence for crustal contamination.The SE China block experienced two main stages of extensional tectonics from late Carboniferous to early Cretaceous.The tectonic evolution of the SE China block from late Devonian to Cretaceous is also evaluated. | Sen Wang Da Zhang Ganguo Wu Absai Vatuva Yongjun Di Pengcheng Yan Haibin Feng Shuai Ma | 2017 | Geoscience Frontiers2017，8，3： | 6 |
| 13 | Biotemplated synthesis of three-dimensional porous MnO/C-N nanocomposites from renewable rapeseed pollen: An anode material for lithium-ion batteries显示文摘锂离子电池(解放) 当前作为可得到的最流行的力量来源之一被认出。到预付展出长期的耐力的解放的构造,大注意对提高他们的差的周期稳定性被给予了。因为解放的表演依赖于采用的电极材料,改进他们的寿命的最有希望的途径是新奇电极材料的设计。我们此处描述合理设计一三维(3D ) 是的多孔的 MnO/C-N nanoarchitecture 为长周期生活解放的阳极材料基于他们从经由一条灵巧的退火沉浸的线路的便宜、可更新、丰富的油菜籽花粉(R 花粉) 的准备。显著地,有它的优化 3D nanostructure 的同样准备的 MnO/C-N 展出了一个高特定的能力(756.5 | Li-Feng Chen Sheng-Xiang Ma Shu Lu Yue Feng Jia Zhang Sen Xin Shu-Hong Yu | 2017 | Nano Research2017，10，1： | 5 |
| 14 | Epigallocatechin-3-gallate inhibits angiotensin Il-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes显示文摘AngiotensinⅡ(All) has been well known to induce cardiomyocyte hypertrophy. Epigallocatechin-3-gallate (EGCG) is the main active comp on ent of green tea and it has bee n show n to exhibit strong cardioprotective potential, although the underlying molecular mechanisms remain unclear. In this study, we investigated the role and mechanism of EGCG in preventing All-induced cardiomyocyte hypertrophy using rat H9c2 cardiomyocytes cells. Reactive oxygen species assay, cell size, and mRNA expression of cardiac hypertrophy markers ANP and BNP were assessed in response to All treatment. In addition, expression of proteins involved in Hippo signaling pathway were determined by western blot analysis. We found that All treatment resulted in significant upregulation of ANP and BNP expression levels and increase in H9c2 cell size, which were markedly attenuated by EGCG treatment. Furthermore, our results suggested that EGCG inhibited Allinduced cardiac hypertrophy via regulating the Hippo signaling pathway. Therefore, EGCG may be an effective agent for preventing cardiac hypertrophy. | Yuan Ma Yongjia Hu Jiawen Wu Junru Wen Sen Li Lijuan Zhang Jie Zhang Yanfei Jue Li | 2019 | Acta Biochimica et Biophysica Sinica2019，51，4： | 4 |
| 15 | Influences of four processing methods on main nutritional components of foxtail millet: A review显示文摘Foxtail millet, originated from China and now cultivated worldwide, is a kind of high dietary fiber whole grain food, and has a high level of vitamins and proteins. Furthermore, foxtail millet has many positive effects on the adjuvant treatment of diabetes, cancer, and cardiovascular diseases because of the abundance in polyphenols. Nonetheless, foxtail millet has poor processing characteristics due to the absence of gluten, restricting the development of foxtail millet products. Studies have demonstrated that heat-moisture treatment, extrusion, superfine grinding, and microbial fermentation are promising methods to improve the processing qualities of foxtail millet. Heat-moisture treatment is helpful to increase the content of resistant starch but has less influence on other components, further reduce the GI value of foxtail millet. The extrusion has positive effects on improving the solubility of foxtail millet starch and increasing the contents of polyunsaturated fatty acid, linoleic and linolenic acids, and adverse effects on reducing the solubility of foxtail millet proteins and causing losses of nutrients due to Maillard reaction. Superfine grinding can reduce the particle size of foxtail millet to obtain a better mouthfeel of foxtail millet products. The superfine foxtail millet flour has better solubility, higher freeze-thaw stability, and lower gelatinization temperature. Microbial fermentation contributes positively to reducing the molecular weight and retrogradation value of foxtail millet starch, degrading rapidly digested starch, and improving the digestibility of foxtail millet protein. This paper briefly introduced the effects of different processing methods on foxtail millet nutrients, aiming to provide references for increasing the variety and improving the quality of foxtail millet products. | Tongshuai Yang Sen Ma Jingke Liu Binghua Sun Xiaoxi Wang | 2022 | Grain & Oil Science and Technology2022，5，3： | 4 |
| 16 | The Erosion Effect of Kapton Film in a Ground-based Atomic Oxygen Irradiation Simulator显示文摘In order to investigate the effect of space environmental factors on spacecraft materials, a ground-based simulation facility for space atomic oxygen(AO) irradiation was developed in our laboratory. Some Kapton film samples were subjected to AO beam generated by this facility. The Kapton films before and after AO exposure were analyzed comparatively using optical microscopy, scanning electronic microscopy, atomic force microscopy, high-precision microbalance, and X-ray photoelectron spectroscopy. The experimental results indicate that the transmittance of Kapton film will be reduced by AO irradiation notably, and its color deepens from pale yellow to brown. Surface roughness of the AO-treated sample is already increased obviously after AO irradiation for 5 hours, and exhibits a flannel-like appearance after 15 hours' exposure in AO beam. The imide rings and benzene rings in kapton molecule are partially decomposed, and some new bonds form during AO irradiation. The mass loss of kapton film increases linearly with the increase of AO fluence, which is resulted from the formation of volatile products, such as CO, CO2 and NOx. The breakage in structure and degradation in properties of AO-treated Kapton film can be attributed to the integrated effect ofimpaction and oxidization of AO beam. The test results agree well with the space flight experimental data. | 王海斗 MA Guozheng XU Binshi XING Zhiguo LI Guolu ZHANG Sen | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，6： | 4 |
| 17 | Origin and Classification of Geothermal Water from Guanzhong Basin,NW China:Geochemical and Isotopic Approach显示文摘Combined with tectonic evolution,a multi-isotopic method(δD,δ18O,87Sr/86Sr and 14C)and hydrochemistry data have been used to study the origin and classification of geothermal water in the Guanzhong Basin.The study shows that geothermal water of Xianli terrace primarily came from northwest direction when accepting recharge.A small amount supply source of geothermal water in Xi’an City is from Qinling Mountain and the principal supply source comes from the west direction,but geothermal water of Chang’an District mainly accepts supply from Qinling Mountain.Based on geothermal environment is open or not,the degree of water-rock interaction,and the origin of geothermal water,geothermal water of the study area can be divided into four types:A,geothermal water of Gushi depression,perfect closed thermal environment and significant water-rock interaction,belonged to residual sedimentary water origin;B,geothermal water of Xianyang City,good closed environment and relatively significant water-rock interaction,belonged to residual sedimentary water origin mixed with fossil leaching water;C,geothermal water of Xi’an City,half closed environment and some water-rock interaction,belonged to fossil leaching water origin;D,geothermal water of Chang’an District,open environment and mixed with modern precipitation,belonged to fossil leaching water origin. | Zhiyuan Ma Xiucheng Li Huiju Zheng Jingbin Li Bei Pei Sen Guo Xuelian Zhang | 2017 | Journal of Earth Science2017，28，4： | 4 |
| 18 | Causes of maize density loss in farmers’ fields in Northeast China显示文摘Increasing plant density is an effective and important way to reduce maize yield gaps in Northeast China. However, the fact is that a significant plant density gap exists between optimum plant density and actual plant density in farmers’ fields.To quantify the density gap between planned planting density and final harvest plant density(HPD), we studied 60 farmers’ fields on three types of soil for three crop seasons from 2015 to 2017 by measuring their plant-plant distance, actual seedlings density(ASD), final HPD and yield. We also explored the potential causes of density loss by digging the places where the seedlings were missing for two consecutive years in 2016–2017. Results show that the three-year average HPD in farmers’ fields was 59 699 plants ha^–1, which was significantly lower than the planned density, including both the machine setting density(MSD;67 962 plants ha^–1) and theoretical plant density(TPD;67 467 plants ha^–1). No significant difference was found in HPD between years and soil types. However, for MSD and TPD, the average value in 2015 was significantly higher than that in 2016 and 2017. No significant difference between soil types was observed. Furthermore,the results from 2016 till 2017 indicated that a lack of seeds in the soil, a failure to germinate due to low-quality seeds,and a lack of seedlings breaking out of the soil due to environmental problems explained approximately 60.88, 10.33 and 28.80% of density loss, respectively. According to our survey, 63% of farmers did not know their own TPD and HPD, and 54% of farmers did not know the density loss. Therefore, we argue that farmers’ limited knowledge of density and density loss is an urgent problem that needs to be solved in maize production. These observations will be useful for determining best management practices for maize production and for providing helpful suggestions for machine improvement. | ZHAO Ying-jie XING Sen ZHANG Qing-song ZHANG Fu-suo MA Wen-qi | 2019 | Journal of Integrative Agriculture2019，18，8： | 4 |
| 19 | New Geochronologic Evidence of Diabases and Their Metallogenic Relationship with the Makeng-Type Iron Deposits in Southwest Fujian, SE China显示文摘Objective The Makeng-type iron deposits are located in Late Paleozoic depression of southwest Fujian Province in the southeast edge of Cathaysia,which are famous for their huge scale and specific ore genesis.Previous studies mainly focus on the ore characteristics,metallogenic setting and the granites in the mining area,and there is still controversy on the ore genesis.Recent research | WANG Sen ZHANG Da WU Ganguo CAO Ke QU Hongjie MA Shuai YU Tengda | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 3 |
| 20 | Field Detection of Chiorophyll-a Concentration in the Sea Surface Layer by an Airborne Oceanographic Lidar显示文摘An airborne oceanographic lidar, with a frequency-tripled Q-switched Nd: YAG laser of 355 nm, has been designed to measure chlorophyll-a (Chl-a) concentration in the sea surface layer by the Ocean Remote Sensing Institute, OUC. The field experi- ment was carried out in the bay which is located south of the Liaodong Peninsula on the 10th of September 2005. After the flight, the raw data were processed and analyzed by the fluorescence-to-Raman ratio method with seawater attenuation coefficients calculated from signal profiles. The results of Chl-a concentration measurements by lidar are shown. The measurements in clear sea water were also compared with those of Chl-a concentration by a Moderate Resolution Imaging Spectroradiometer (MODIS). | LIU Zhishen MA Sen WANG Xin LI Zhigang | 2008 | Journal of Ocean University of China2008，7，1： | 3 |
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