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| 1 | Socio-cultural determinants of timely and delayed treatment of Buruli ulcer: implications for disease control显示文摘Introduction:Public health programmes recommend timely medical treatment for Buruli ulcer(BU)infection to prevent pre-ulcer conditions from progressing to ulcers,to minimise surgery,disabilities and the socio-economic impact of BU.Clarifying the role of socio-cultural determinants of timely medical treatment may assist in guiding public health programmes to improve treatment outcomes.This study clarified the role of socio-cultural determinants and health system factors affecting timely medical treatment for BU in an endemic area in Ghana.Methods:A semi-structured explanatory model interview based on the explanatory model interview catalogue(EMIC)was administered to 178 BU-affected persons.Based on research evidence,respondents were classified as timely treatment(use of medical treatment 3 months from awareness of disease)and delayed treatment(medical treatment 3 months after onset of disease and failure to use medical treatment).The outcome variable,timely treatment was analysed with cultural epidemiological variables for categories of distress,perceived causes of BU,outside-help and reasons for medical treatment in logistic regression models.The median time for the onset of symptoms to treatment was computed in days.Qualitative phenomenological analysis of respondents’narratives clarified the meaning,context and dynamic features of the relationship of explanatory variables with timely medical treatment.Results:The median time for initiating treatment was 25 days for pre-ulcers,and 204 days for ulcers.Income loss and use of herbalists showed significantly negative associations with timely treatment.Respondents’use of herbalists was often motivated by the desire for quick recovery in order to continue with work and because herbalists were relatives and easily accessible.However,drinking unclean water was significantly associated with timely treatment and access to health services encouraged timely treatment(OR 8.5,p=0.012).Findings show that health system factors of access are responsible for non-compliance to treatment regimes.Conclusions:Findings highlight the importance of an integrated approach to BU control and management considering the social and economic features that influence delayed treatment and factors that encourage timely medical treatment.This approach should consider periodic screening for early case-detection,collaboration with private practitioners and traditional healers,use of mobile services to improve access,adherence and treatment outcomes. | Mercy M Ackumey Margaret Gyapong Matilda Pappoe Cynthia Kwakye Maclean Mitchell G Weiss | 2012 | Infectious Diseases of Poverty2012,1,1: | 3 |
| 2 | B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy显示文摘 | Vijay K Kuchroo Mercy Prabhu Das Julia A Brown Ann M Ranger Scott S Zamvil Raymond A Sobel Howard L Weiner Nasrin Nabavi Laurie H Glimcher | 1995 | Cell1995,,5: | 2 |
| 3 | Nuclear transcription factor kappa B (NF-kappa B)显示文摘 | Merci P eigneur M Bilhou-Nabera C a al | 1998 | Rev Med Interne1998,19,12: | 1 |
| 4 | Role of Respiratory Viruses in Acute Upper and Lower Respiratory Tract Illness in the First Year of Life显示文摘 | Merci M H Mbbs K Nicholas H | 2006 | Pediatr Infect Dis J2006,25,: | 1 |
| 5 | Childhood leber hereditary optic neuropathy, a case of a 6-year-old girl with loss of vision显示文摘 | BALAYRE S GICQUEL J J MERCIE M | 2003 | Journal Franeais d'' Ophtalmologie2003,26,10: | 1 |
| 6 | Nickel containing MCM-41 and A1MCM-41 mesoporous mo- lecular sieves: Characteristics and activity in the hydrogena- tion of benzene 显示文摘 | WOJCIESZAK R MONTEVERDI S MERCY M | 2004 | Appl Catal A: General2004,268,12: | 1 |
| 7 | Role of Respiratory Viruses in Acute Upper and Lower Respiratory Tract Illnessin the First Year of Life显示文摘 | Merci M H Mbbs K Nicholas H | 2006 | Pediatric Infectious Disease2006,,: | 1 |
| 8 | Assay of plasma thrombomodulin in systemic diseases显示文摘 | Mercie P Seigneur M Constans J | 1997 | Rev Med lnrene1997,18,2: | 1 |
| 9 | Nickel Containing MCM-41 and AlMCM-41 Mesoporous Molecular Sieves: Characteristics and Activity in the Hydrogenation of Benzene显示文摘 | Wojcieszak R Monteverdi S Mercy M | 2004 | Appl Catal A:General2004,268,12: | 1 |
| 10 | An agglutinin with unique specificity for N-glycolyl slalic acid residues of thyroglobulin in the hemolymph of a marine crab Scylla serrata (Forskal) 显示文摘 | Mercy P D Sr Ravindranath M H | 1992 | Experientia1992,48,5: | 1 |
| 11 | Endovascular treatment of a patient with an aneurysm of the proper hepatic artery and aduodenal fistula显示文摘 | Merci FI Mauricc AB Erik M | 2011 | Vase Surg2011,53,3: | 1 |
| 12 | Purification and characterization of N-glycolylneuraminic-acidspecific lectin from Scylla serrala显示文摘 | Mercy S P D Ravindranath M H | 1993 | Eur J Biochem1993,215,: | 1 |
| 13 | Three-di- mensional power Doppler angiography in endometrial cancer: correlation with tumor characteristics 显示文摘 | GALVAN R MERCiE L JURADO M | 2010 | Ultra- sound Obstet Gynecol2010,35,6: | 1 |
| 14 | Nickel containing MCM-41 and AlMCM-41 mesoporous molecular sieves characteristics and in the hydrogenation of benzene显示文摘 | WOJCIESZAK R MONTEVERDI S MERCY M | 2004 | Appl Catal A:General2004,268,12: | 1 |
| 15 | Study of nickel catalysts supported on silica of low surface area and prepared by reduction of nickel acetate in aqueous hydrazine显示文摘 | BOUDJAHEM AG MONTEVERDI S MERCY M | 2004 | Journal of Catalysis2004,221,2: | 1 |
| 16 | Study of nickel catalysts supported on silica of low surface area and prepared by reduction of nickel acetate in aquenous hydrazine显示文摘 | A G Boudjahem S Monteverdi M Mercy | 2004 | Journal of Catalysis2004,221,: | 1 |
| 17 | Rapid assessment of longitudinal systolic left ventrieular function using speckle tracking of the mitral annulus显示文摘 | Buss S J Mercies D Emami M | 2012 | Clin Res Cardiol2012,101,4: | 1 |
| 18 | Childhood Leber hereditary optic neuropathy:a case of a 6-year-old girt with loss of vision 显示文摘 | Balayre S Gicquel JJ Mercie M | 2003 | Fr Ophtalmol2003,26,: | 1 |
| 19 | Morphological variation in the Indian gooseberries ( Phyllanthus emblica and Phyllanthus indofischer ) and the chloroplast trnL (UAA) intron as candidate gene for their identification 显示文摘 | SANGEETHA N MERCY S KAVITHA M | 2010 | Plant Genetic Resources : Char- acterization and Utilization2010,8,3: | 1 |
| 20 | Clinical manifestations of pediatric psoriasis: results of a multicenter study in the United States 显示文摘 | Mercy K Kwasny M Cordoro KM | 2013 | Pediatr Dermatol2013,30,4: | 1 |