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| 1 | 贵州遵义牛蹄塘组黑色岩系的硒同位素变化及其环境指示初探显示文摘西南早寒武世牛蹄塘组是分布在中国南方扬子地台的一套黑色岩系,区域上发育有典型富集多金属元素的硫化物矿化层。选取遵义松林小竹牛蹄塘组下部富硒、钼、镍等元素的黑色岩系剖面,利用Se同位素初步探讨了该剖面岩石的沉积环境和硒的可能来源。结果表明,小竹牛蹄塘组下部剖面黑色岩系的δ82/76SeSRM3149比值变化较大,下部底层含碳斑脱岩与磷块岩的变化范围在-4.35‰^+4.11‰之间;中间镍钼层及碳质页岩、碳质碳酸盐岩的δ82/76SeSRM3149变化范围窄,平均值为0.91‰±0.23‰(n=4);上层碳质页岩为-1.24‰。结合已发表的钼同位素数据,认为中间岩石沉积于缺氧/无氧环境,但存在盆地海水与热液或充氧水团的混合;下层的岩石曾一度位于充氧与贫氧环境的边界面,局部岩石曾暴露地表经历了较强的风化和蚀变作用,海水中硒有可能来自底部富硒斑脱岩的氧化淋滤或海底热液。据此推测遵义松林小竹牛蹄塘组下部岩石的沉积环境极可能处在局限盆地靠近陆地的边缘部分,经历了充氧→贫氧→缺氧/无氧→贫氧的演化阶段。 | 朱建明 Johnson Thomas M 罗泰义 朱祥坤 | 2008 | 岩石矿物学杂志2008，27，4： | 18 |
| 2 | Degradation of organic pollutants by a Co_3O_4 -graphite composite electrode in an electro-Fenton-like system显示文摘A novel composite electrode was constructed by pressing together Co3O4 and graphite and it was used as the cathode in an electro-Fenton-like (EFL) system. The poor electron transport characteristic of Co3O4 was overcome by incorporating graphite. In situ electro-catalytic generation of hydroxyl radicals (·OH) occurred at high current efficiencies from pH 2-10, extending the traditional Fenton reaction pH range. Cyclic voltammetry and AC impedance spectrometry were used to characterize the composite electrode. The ability of the EFL system to degrade organic compounds was investigated using sulforhodamine B (SRB) and 2,4-dichlorophenol (2,4-DCP) as probes. Decoloration of SRB (1.0×10-5 mol/L) was complete (100%) in 150 min and SRB was effectively degraded from pH 2-10. The decomposition of SRB was studied using Fourier transform infrared spectroscopy (FT-IR) and total organic carbon (TOC) analysis and results indicated that the final degradation products were carbon dioxide, carboxylic acids and amines. The EFL system also decomposed 2,4-DCP and the degradation was 98.6% in 240 min. Electro-catalytic degradation of SRB occurs by a ·OH mechanism. After 5 times reused, the degradation rate of SRB did not significantly slow down. The electrode shows excellent potential for use in advanced oxidation processes (AOPs) used to treat persistent organic pollutants (POPs) in wastewater. | LIU Shuan GU Yan WANG ShuLian ZHANG Yu FANG YanFen JOHNSON David M HUANG YingPing | 2013 | Chinese Science Bulletin2013，58，19： | 18 |
| 3 | Phytochemical and anti-bacterial activity of epidermal glands extract of Christella parasitica (L.) H. Lev.显示文摘Objective:To study the morphology,biochemistry and bioactivity of the epidermal glands of the glandular morphotype of Christella parasitica(C.parasitica)(L.) H.Lev.Methods: Morphological studies on epidermal glands were earned out by using light microscope and scanning electron microscope.To prepare the extract,the shade-dried fronds of glandular morphotype were soaked in acetone.For antibacterial studies paper disc method was followed by using various pathogenic bacteria.Results:Detailed micromorphological,phytochemical and bioactivity studies on a medicinal fern C.parasitica(L.) H.Lev.showed its inlraspecific variation in antibacterial activity.The presence or absence of the epidermal glands was the key factor for antibacterial activity in the morphovariants of this species.The epidermal glands were orange-coloured,stalked and elongated ones of about 84.2μm×45μm,and distributed on the undersurface of cosla,coslules and veins in croziers,young and mature leaves.Frequency of glands varied from 15/cm on costa in mature leaves to 140/cm on costules in croziers.The acetone extract of the glands showed antibacterial activities and also toxic effect against mosquito larvae and tadpoles of frog.Preliminary phytochemical analysis and HPLC studies of the gland extract showed the presence of various kinds of terpenoids,alkaloids,tannins,saponins and flavonoids in it.Conclusions:The present study shows that epidermal glands of the glandular morphotype of C. parasitica(L.) H.Lev.have several bioactive compounds and such rare moiphovariant should be conserved in nature.The next step is to isolate the pure compounds and to screen the bioactivity of individual compounds of the epidermal glands. | Paul Raj K Irudayaraj V Johnson M Patric Raja D | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 14 |
| 4 | Dynamic Contrast-Enhanced Perfusion MR Imaging Measurements of Endothelial Permeability: Differentiation between Atypical and Typical Meningiomas显示文摘BACKGROUND: AND PURPOSE: The measurement of relative cerebral blood volume (rCBV) and the volume transfer constant (K(trans)) by means of dynamic contrast-enhanced (DCE) perfusion MR imaging (pMRI) can be useful in characterizing brain tumors. The purpose of our study was to evaluate the utility of these measurements in differentiating typical meningiomas and atypical meningiomas. METHODS: Fifteen patients with pathologically confirmed typical meningiomas and seven with atypical meningiomas underwent conventional imaging and DCE pMRI before resection.rCBV measurements were calculated by using standard intravascular | Law M Zagzag D Golfinos JG Knopp EA Johnson G | 2003 | 中国神经肿瘤杂志2003，1，3： | 10 |
| 5 | Antibacterial activity of leaves and inter-nodal callus extracts of Mentha arvensis L显示文摘Objective:To determine the anti-bacterial efficacy of chloroform,ethanol,ethyl acetate and water extracts of inter-nodal and leaves derived calli extracts from Mentha arvensis(M.arvensis) against Salmonella typhi(S.typhi),Streptococcus pyogenes(S.pyogenes),Proteus vulgaris(P. vulgaris) and Bacillus subtilis(B.subtilis).Methods:The inter-nodal and leaves segments of M.arvensis were cut into 0.5-0.7 cm in length and cultured on Murashige and Skoog solid medium supplemented with 3%sucrose,gelled with 0.7%agar and different concentration of 2,4-Dichlorophenoxyacetie acid(2,4-D) either alone or in combinations.The preliminary phytochemical screening was performed by Brindha et al method.Antibacterial efficacy was performed by disc diffusion method and incubated for 24 h at 37℃.Results:Maximum percentage of callus formation(inter-nodal segments 84.3±0.78;leaves segments 93.8±1.27) was obtained on Murashige and Skoog’s basal medium supplemented with 3%sucrose and 1.5 mg/L of 2,4-D.The ethanol extracts of leaves derived calli showed the maximum bio-efficacy than other solvents.The leaves and stem derived calli extracts on Proteus sp.showed that the plants can be used in the treatment of urinary tract infection associated with Proteus sp.Through the bacterial efficacy studies,it is confirmed that the in vitro raised calli tissue was more effective compared to in vivo tissue.Conclusions:The bio-efficacy study confirmed that the calli mediated tissues showed the maximum zone of inhibition.The present study paved a protocol to establish high potential cell lines by in vitro culture. | Johnson M Wesely EG Kavitha MS Uma V | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，3： | 9 |
| 6 | 板块构造机制在显生宙初期发生转变显示文摘虽然目前对于板块构造何时成为主要构造机制存在争议,但是研究者普遍认为在古太古代已经完成转变。元古代时期,哥伦比亚超大陆向罗迪尼亚超大陆的转换,并未发生超大陆的完全裂解和聚合,而是岩石圈和环境的相对稳定期。相比之下,成冰期至今则发育有大量的被动大陆边缘,以及在425~225 Ma期间大幅增加的裂谷和大陆岛弧长度,表明存在与潘吉亚超大陆形成密切相关的激烈板块构造活动。 | 袁超(编译) Brown M Kirkland C L Johnson T E | 2020 | 矿物岩石地球化学通报2020，39，4： | 9 |
| 7 | Role of microbial dysbiosis in the pathogenesis of esophageal mucosal disease:A paradigm shift from acid to bacteria?显示文摘Genomic sequencing,bioinformatics,and initial speciation(e.g.,relative abundance)of the commensal microbiome have revolutionized the way we think about the“human”body in health and disease.The interactions between the gut bacteria and the immune system of the host play a key role in the pathogenesis of gastrointestinal diseases,including those impacting the esophagus.Although relatively stable,there are a number of factors that may disrupt the delicate balance between the luminal esophageal microbiome(EM)and the host.These changes are thought to be a product of age,diet,antibiotic and other medication use,oral hygiene,smoking,and/or expression of antibiotic products(bacteriocins)by other flora.These effects may lead to persistent dysbiosis which in turn increases the risk of local inflammation,systemic inflammation,and ultimately disease progression.Research has suggested that the etiology of gastroesophageal reflux disease-related esophagitis includes a cytokine-mediated inflammatory component and is,therefore,not merely the result of esophageal mucosal exposure to corrosives(i.e.,acid).Emerging evidence also suggests that the EM plays a major role in the pathogenesis of disease by inciting an immunogenic response which ultimately propagates the inflammatory cascade.Here,we discuss the potential role for manipulating the EM as a therapeutic option for treating the root cause of various esophageal disease rather than just providing symptomatic relief(i.e.,acid suppression). | Steve M D'Souza Kevin Houston Lauren Keenan Byung Soo Yoo Parth J Parekh David A Johnson | 2021 | World Journal of Gastroenterology2021，27，18： | 8 |
| 8 | 抗菌蜂蜜预防腹膜透析相关感染:一项随机对照试验显示文摘背景 目前缺少指导预防腹膜透析相关感染策略的研究证据。抗菌蜂蜜作为一种新型、廉价、有效的局部预防性使用的药物,不会诱导细菌耐药。因此,我们评估,对鼻内定植金黄色葡萄球菌的患者,与同时进行腹膜管外出口部位常规护理加上鼻内莫匹罗星去定植的方法相比,腹膜管外出口部位每日使用蜂蜜,是否会延迟首次出现腹膜透析相关感染的时间。 | Johnson D W Badve S V Pascoe E M 陈玉华 | 2014 | 中国感染控制杂志2014，13，2： | 7 |
| 9 | Chromatographic finger print analysis of steroids in Aerva lanata L by HPTLC technique显示文摘Objective:To determine the chemical profile and steroids composition of the medicinally important plant Aerva lanata(A.lanata) L.Methods:Preliminary phytochemicul screening was done by the method as Harborne described.HPTLC studies were canied out as Harborne and Wagner et al described.The Ethyl acetate-ethanol-water(8:2:1.2) was employed as mobile phase for glycosides.Results:The desired aim was achieved using Chloroform-acetone(8:2) as the mobile phase.The methanolic extract of stem,leaves,root,flower and seeds of A.lanata showed the presence of 30 different types of steroids with 30 different Rf values from 0.04 to 0.97. Maximum number(11) of steroids has been observed in leaves followed by root(10).Conclusions: HPTLC profile of steroids has been chosen here to reveal the diversity existing in A.lanata.Such finger printing is useful in differentiating the species from the adulterant and act as biochemical markers for this medicinally important plant in the pharma industry and plant systematic studies. | Yamunadevi Mariswamy Wesely Edward Gnaraj Johnson M | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，6： | 6 |
| 10 | 慢性淋巴细胞白血病诊治指南显示文摘流行病学
慢性淋巴细胞白血病(CLL)在西方国家很常见,占65岁以上白血病患者的65%.中位发病年龄65~70岁.30岁以下极为罕见,但20%~30%病例于55岁前发病,年发病率约3/10万.欧洲、澳大利亚、北美白人以及黑人的发病率是印度、中国及日本的20~30倍.男女之比约2:1.无确凿证据显示,接触化学物质和射线、饮食、吸烟、病毒感染和自身免疫性疾病为本病的高危因素,但患者一级和二级亲属淋巴系统恶性肿瘤发病率增高.许多家族尚存在患者后代发病年龄更早、病情更重的现象.经治和未治患者第二肿瘤发病率增高. | Oscier D Fegan C Hillman P Illide T Johnson S Maguir P Matutes M Milligan D 孙蕾 高举 | 2005 | 国外医学(输血及血液学分册)2005，28，1： | 6 |
| 11 | New Pd(Ⅱ)- and Ni(Ⅱ)-Based Catalysts for Polymerization of Ethylene and α-Olefins显示文摘 | Johnson L K Killian C M Brookhart M | | 0，，： | 6 |
| 12 | 长期应用埃索美拉唑是维持已愈合糜烂性食管炎疗效及控制胃食管反流症状的有效方法显示文摘 | Johnson DA Benjamin SB Vakil NB Goldstein JL Lamet M Whipple J Damico D Hamelin B 钟捷 | 2002 | 中华消化杂志2002，22，12： | 6 |
| 13 | In vivo and in vitro phytochemical and antibacterial efficacy of Baliospermum montanum (Willd.) Muell.Arg.显示文摘Objective:To evaluate the phytochemical and anti-bacterial potential of mother plants in vivo and in vitro derived callus of Baliospermum montanum(B.montanum)(Willd.) Muell.-Arg. leaves and root.Methods:The in vitro derived rootlets and leaves segments of B.montanum were cut into 0.5-0.7 cm in length and cultured on Murashige and Skoog solid medium supplemented with 3%sucrose,gelled with 0.7%agar and different concentration of 2,4-D either alone or in combinations.The preliminary phytochemical screening was performed by Harborne method.Antibacterial efficacy was performed by well diffusion method and incubated for 24 h at 37℃.Results:The highest percentage of callus formation(leaves segments 86.9±0.56:root segments 78.7±0.51) was obtained on Murashige and Skoog’s basal medium supplemented with 3%sucrose and 2.0 mg/L of 2.4-Dichlorophenoxy acetic acid.The phytochemical study revealed the high quantity presence of steroids,triterpenoids,glycosides,saponins,alkaloids,flavanoids, phenolic compounds,tannins,sugars etc of root and leaves derived calli.The ethanol extract of leaves segment derived calli of B.montanum showed the maximum solubility and antimicrobial activity with the MIC ranged from 100 to 200μL.Conclusions:The preliminary phytochemical study confirmed that the calli mediated tissues showed the higher percentage of metabolite constituents and extraction value compared to the in vivo leaves and roots.The present study observation suggested that a possibility to establish high yielding genotypes by in vitro culture for production of medicinally important bioactive compounds. | Johnson M Wesely EG Zahir Hussain MI Selvan N | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 6 |
| 14 | Re- sponses in ovulation rate, embryonal survival, and litter traits in swine to 14 generations of selection to increase litter size 显示文摘 | JOHNSON R K NIELSEN M K CASEY D S | 1999 | J Anim Sci1999，77，3： | 5 |
| 15 | Copolymerization of Ethylene and Propyiene with Functionalized Vinyl Monomers by PalladiumII) Catalysts显示文摘 | Johnson L K Killian C M Arthur S D | | 0，，： | 4 |
| 16 | Radial artery access site complications during cardiac procedures,clinical implications and potential solutions: The role of nitric oxide显示文摘Percutaneous coronary intervention for the treatment of coronary artery disease is most commonly performed in the UK through the radial artery,as this is considered to be safer than the femoral approach.However,despite improvements in technology and techniques,complications can occur.The most common complication,arterial spasm,can cause intense pain and,in some cases,procedural failure.The incidence of spasm is dependent on several variables,including operator experience,artery size,and equipment used.An antispasmolytic cocktail can be applied to reduce spasm,which usually includes an exogenous nitric oxide(NO)donor(glyceryl trinitrate).NO is an endogenous local vasodilator and therefore is a potential target for anti-spasm intervention.However,systemic administration can result in unwanted side-effects,such as hypotension.A method that adopts local delivery of NO might be advantageous.This review article describes the mechanisms involved in radial artery spasm,discusses the advantages and disadvantages of current strategies to reduce spasm,and highlight the potential of NO-loaded nanoporous materials for use in this setting. | Emma M Coghill Timothy Johnson Russell E Morris Ian L Megson Stephen J Leslie | 2020 | World Journal of Cardiology2020，12，1： | 4 |
| 17 | Prevalence of unsuspected thyroid nodules in adults on contrast enhanced 16-and 64-MDCT of the chest显示文摘AIM: To determine the prevalence of unsuspected thyroid nodules on contrast enhanced 16and 64-modified discrete cosine transform (MDCT) of the chest, in a population of adult outpatients imaged for indications other than thyroid disease. METHODS: This retrospective study involved review of intravascular contrast-enhanced MDCT scans of the chest from 3077 consecutive adult outpatients, to identify unsuspected thyroid nodules. Exclusion criteria included history of thyroid cancer, known thyroid nodules or thyroid disease and risk factors for thyroid cancer, as evidenced by their medical records. One of 9 radiologists recorded number of nodules, location and bidirectional measurement of largest nodule, as well as amount of thyroid visualized on the chest computed tomography (CT). Presence of nodule was correlated with age, gender, race and percentage of thyroid imaged. RESULTS: A total of 2510 (2510/3077 or 81.6%) study subjects were included in the data analysis; among them,one or more nodules were identified in 629 subjects (629/2510 or 25.1%), with 242 (242/629 or 38.5%) having multiple nodules. Patients with nodule(s) were significantly older than those without (64 ± 13 years vs 58 ± 14 years, P < 0.0001), and female gender was associated with presence of nodule(s) (373/1222 or 30.5% vs 256/1288 or 19.9%, P < 0.0001). Women were also more likely having multiple nodules (167/373 or 44.8%) compared to men (75/256 or 29.3%, P < 0.0001). The majority of nodules (427/629 or 67.9%) were less than 1 cm. CONCLUSION: This retrospective review revealed a prevalence of 25.1% for unsuspected thyroid nodules on contrast-enhanced chest CT. | Sameer Ahmed Pamela T Johnson Karen M Horton Atif Zaheer Saline Tsai Elliot K Fishman | 2012 | World Journal of Radiology2012，4，7： | 4 |
| 18 | Preliminary phytochemical and antimicrobial studies on a spike-moss Selaginella inaequalifolia(hook.& grev.) Spring显示文摘Objective:To screen the anti-cancer spike-mosses for the presence of various bioactivities and to identify the important bioactive chemicals present in Selaginella inaequalifolia(S. inaequalifolia)(Hook.& Grev.) Spring.Methods:Preliminary phytochemical screening was done by following the method of Brindha et al.Antimicrobial study was carried out by disc diffusion method.Results:Results of preliminary phytochemical screening on five different extracts(petroleum ether,benzene,chloroform,ethanol and distilled water) of the spike-moss S.inaequalifolia show the presence steroids,triterpenes,phenolic group,tannin,sugars and catechin.Alkaloids,amino acids,anthraquinone and reducing sugar did not show any positive result.Among the five different extracts,ethanol and chloroform extracts show the presence of maximum number(4 each) of compounds.The results on antimicrobial studies show that all the three microbes[Staphylococcus aureus(S.aureus),Escherichia coli(E.coli) and Candida albicans (C.albicans)]tested are resistant to the ethanol extract and susceptible to petroleum ether extract.The petroleum ether extract shows maximum inhibition with 45 mm of inhibition zone in C.albicans.The inhibition zone in S.aureus and E.coli are 26 mm and 22 mm respectively. Conclusions:The present study shows S.inaequalifolia having potent antibacterial and anticandidal activities. | Varaprasadham Irudayaraj Janaky M Marimuthu Johnson Nallayan Selvan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，12： | 4 |
| 19 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002，，6： | 3 |
| 20 | Electrochemical extraction of lithium from LiMn2O4 显示文摘 | Thackeray M M Johnson P J | 1984 | Mater Res Bull1984，19，： | 2 |
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