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| 1 | Galectin-3 and IL-33/ST2 axis roles and interplay in dietinduced steatohepatitis显示文摘Immune reactivity and chronic low-grade inflammation(metaflammation) play an important role in the pathogenesis of obesity-associated metabolic disorders, including type 2 diabetes and nonalcoholic fatty liver disease(NAFLD), a spectrum of diseases that include liver steatosis, nonalcoholic steatohepatitis(NASH), fibrosis, and cirrhosis. Increased adiposity and insulin resistance contribute to the progression from hepatic steatosis to NASH and fibrosis through the development of proinflammatory and profibrotic processes in the liver, including increased hepatic infiltration of innate and adaptive immune cells, altered balance of cytokines and chemokines, increased reactive oxygen species generation and hepatocellular death. Experimental models of dietary-induced NAFLD/NASH in mice on different genetic backgrounds or knockout mice with different immune reactivity are used for elucidating the pathogenesis of NASH and liver fibrosis. Galectin-3(Gal-3), a unique chimera-type β-galactoside-binding protein of the galectin family has a regulatory role in immunometabolism and fibrogenesis. Mice deficient in Gal-3 develop pronounced adiposity, hyperglycemia and hepatic steatosis, as well as attenuated liver inflammation and fibrosis when fed an obesogenic high-fat diet. Interleukin(IL)-33, a member of the IL-1 cytokine family, mediates its effects through the ST receptor, which is present on immune and nonimmune cells and participates in immunometabolic and fibrotic disorders. Recent evidence, including our own data, suggests a protective role for the IL-33/IL-33R(ST2) signaling pathway in obesity, adipose tissue inflammation and atherosclerosis, but a profibrotic role in NASH development. The link between Gal-3 and soluble ST2 in myocardial fibrosis and heart failure progression has been demonstrated and we have recently shown that Gal-3 and the IL-33/ST2 pathway interact and both have a profibrotic role in diet-induced NASH. This review discusses the current evidence on the roles of Gal-3 and the IL-33/ST2 pathway and their interplay in obesity-associated hepatic inflammation and fibrogenesis that may be of interest in the development of therapeutic interventions to prevent and/or reverse obesity-associated hepatic inflammation and fibrosis. | Nada Pejnovic Ilija Jeftic Nemanja Jovicic Nebojsa Arsenijevic Miodrag L Lukic | 2016 | World Journal of Gastroenterology2016，22，44： | 9 |
| 2 | 血细胞分离机采集干细胞效果观察显示文摘目的探讨Amicus血细胞分离机的MNC程序采集外周血干细胞的效果。方法用Amicus血细胞分离机的MNC程序采集健康供者和肿瘤患者外周血干细胞;供者给予G-CSF动员,患者采用化疗加G-CSF动员。用流式细胞仪检测CD34^+抗原表达细胞数。供患者共采集了53次,处理(8±2)个循环,处理抗凝全血(11420±2401)ml,时间(236±28)min,抗凝剂(957±195)ml。结果采集CD34+细胞(235.26±298.53)×10~6,MNC的采集效率为(53.05±39.03)%;患/供者采集前外周血CD34^+计数>0.04×10~9/L(n=28),采集CD34^+细胞为(4.94±4.57)×10~6/kg;而当患/供者采集前外周血CD34^+计数<0.04×10~9/L(n=25),采集CD34^+细胞为(1.07±0.64)×10~6/kg;所采集的干细胞制品中血小板含量为(5.57±4.26)×10^(10)/袋。单采后患/供者Plt、Hb、Hct分别下降14.79%,12.21%和12.23%,所有程序没有观察到严重的副反应。结论Amicus血细胞分离机的MNC采集程序能安全地采集到血小板含量低、高产量的异体和自体CD34^+细胞。 | 洪缨 孙启凤 Ljubisa Lukic | 2005 | 中国输血杂志2005，18，5： | 6 |
| 3 | Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression显示文摘BACKGROUND Ulcerative colitis(UC)is a chronic disease characterized by inflammation of intestinal epithelium,primarily of the colon.An increasing prevalence of metabolic syndrome(MetS)in patients with UC has been documented recently.Still,there is no evidence that MetS alters the course of the UC.AIM To test the influence of the MetS on the severity of UC and the local and systemic immune status.METHODS Eighty nine patients with de novo histologically confirmed UC were divided in two groups,according to ATP III criteria:Group without MetS(no MetS)and group with MetS.RESULTS Clinically and histologically milder disease with higher serum level of immunosuppressive cytokine interleukin-10(IL-10)and fecal content of Galectin-3(Gal-3)was observed in subjects with UC and MetS,compared to subjects suffering from UC only.This was accompanied with predomination of IL-10 over pro-inflammatory cytokines tumor necrosis factorα(TNF-α),interleukin-6(IL-6),and interleukin-17(IL-17)in the sera as well as Gal-3 over TNF-αand IL-17 in feces of UC patients with MetS.Further,the patients with both conditions(UC and MetS)had higher percentage of IL-10 producing and Gal-3 expressing innate and acquired immune cells in lamina propria.CONCLUSION Local dominance of Gal-3 and IL-10 over pro-inflammatory mediators in patients with MetS may present a mechanism for limiting the inflammatory process and subsequent tissue damage in UC. | Marina Jovanovic Bojana Simovic Markovic Nevena Gajovic Milena Jurisevic Aleksandar Djukic Ivan Jovanovic Nebojsa Arsenijevic Aleksandra Lukic Natasa Zdravkovic | 2019 | World Journal of Gastroenterology2019，25，43： | 5 |
| 4 | A resilience-based approach in managing the closure and abandonment of large mine tailing ponds显示文摘Mining tailing ponds are large infrastructure objects whose life cycle spans over several decades.They are indispensable for certain types of mines where technological process produces and rejects mud.They also have potential to generate risks for human life,property and environment.For that reason,it is essential to adequately manage them throughout all the stages of their life cycle.The phase of their closure and abandonment is less studied and understood.The paper proposes a holistic resilience-based approach for analyzing this phase of their life cycle.The proposed methodology is validated through a case study at an actual surface iron ore mine in Bosnia and Herzegovina. | Dragan Komljenovic Lazar Stojanovic Vladimir Malbasic Aleksandar Lukic | 2020 | International Journal of Mining Science and Technology2020，30，5： | 4 |
| 5 | Primary retroperitoneal mucinous cystadenoma:A case report显示文摘Primary retroperitoneal mucinous cystic tumors are extremely rare.These tumors can be classified as a primary retroperitoneal mucinous cystadenoma with or without borderline malignancy or primary retroperitoneal mucinous cystadenocarcinoma.The most common of these is primary retroperitoneal mucinous cystadenoma,which almost always occurs in female patients;only ten cases have been reported in males.The most common clinical findings for this tumor type include nonspecific abdominal pain and a palpable abdominal mass.A definitive diagnosis is usually obtained from histopathology after surgical excision.Here,we report the case of a 60-year-old female patient who complained of abdominal pain that had been present for 3 mo and presented with a palpable abdominal mass.Multidetector computed tomography scanning revealed a large,unilocular cystic mass in the left retroperitoneal space.Surgical intervention was performed and the tumor was completely removed.Histopathologic examination confirmed that the tumor was a primary retroperitoneal mucinous cystadenoma.Two years after surgery,the patient remains disease free. | Srbislav Knezevic Igor Ignjatovic Snezana Lukic Slavko Matic Vladimir Dugalic Djordje Knezevic Marjan Micev Sanja Dragasevic | 2015 | World Journal of Gastroenterology2015，21，17： | 3 |
| 6 | Interleukin‐33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells显示文摘 | Ivan P. Jovanovic Nada N. Pejnovic Gordana D. Radosavljevic Jelena M. Pantic Marija Z. Milovanovic Nebojsa N. Arsenijevic Miodrag L. Lukic | 2014 | Int. J. Cancer2014，，： | 2 |
| 7 | 跨学科症状网络评估(WISE)的设计、构建与技术应用-对口面痛及颞下颌关节紊乱病的探索性建议(译文)显示文摘一、二、三级医疗机构都涉及功能障碍及疼痛相关疾病的诊治过程。对于各级医疗机构而言,收集可靠、实用的患者数据对高质量的个性化诊疗与临床研究有着重要意义。因此,患者自身数据报告的重要性愈加引起人们的重视。然而,在询问病史的过程中,想要收集与患者症状相关的长期、系统的高质量数据往往十分困难。收集可靠而实用的数据比研究生理、心理综合评估参数更加复杂。 | 吴训 王丹丹 Dominik A.Ettlin Isabelle Sommer Ben Bronnimann Mei-Yin Hou Nenad Lukic Beat Steiger Sergio Maffioletti Jorg Scheidt | 2018 | 现代口腔医学杂志2018，32，2： | 2 |
| 8 | ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma显示文摘 | Ivan Jovanovic Gordana Radosavljevic Maja Mitrovic Vanda Lisnic Juranic Andrew N. J. McKenzie Nebojsa Arsenijevic Stipan Jonjic Miodrag L. Lukic | 2011 | Eur. J. Immunol2011，，： | 2 |
| 9 | IL-33/ST2 axis in innate and acquired immunity to tumors显示文摘 | Ivan P. Jovanovic Nada N. Pejnovic Gordana D. Radosavljevic Nebojsa N. Arsenijevic Miodrag L. Lukic | 2012 | OncoImmunology2012，，： | 2 |
| 10 | The roles of Galectin-3 in autoimmunity and tumor progression显示文摘 | Gordana Radosavljevic Vladislav Volarevic Ivan Jovanovic Marija Milovanovic Nada Pejnovic Nebojsa Arsenijevic Daniel Hsu Miodrag Lukic | 2012 | Immunologic Research2012，，1： | 2 |
| 11 | Cellular and molecular interactions between immune system and bone显示文摘 | Katavic V Lukic IK | 2001 | Croat Med J2001，42，4： | 1 |
| 12 | Effects of nimodipine on cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage treated by endovascular coiling 显示文摘 | Mijailovic M Lukic S Laudanovie D | 2013 | Adv Clin Exp Med2013，22，1： | 1 |
| 13 | Roles of coactosin-like protein (CLP) and 5-1ipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis显示文摘 | Basavarajappa D Wan M Lukic A | 2014 | Proc Nail Acad Sci U S A2014，111，11： | 1 |
| 14 | Prognostic valve of CA125 kinetics and half-life in advanced ovarian cancer 显示文摘 | CALAKOVIS S LUKIC V MITROVIC | 2000 | Int J Biol Marker2000，15，2： | 1 |
| 15 | Efficiency of ultrasonic Ver- tex III hypsometer compared to the most commonly used hypsome- ters in Croatian forestry显示文摘 | Boris M Cavlovic J Lukic N | 2005 | Croatian Journal of Forest Engineer* ing2005，26，2： | 1 |
| 16 | Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis显示文摘 | Vladislav Volarevic Ahmed Al-Qahtani Nebojsa Arsenijevic Sladjana Pajovic Miodrag L. Lukic | 2009 | Autoimmunity2009，，4： | 1 |
| 17 | An alkyl polyglucoside- mixed emulsifier as stabilizer of emulsion systems: the influence of colloidal structure on emulsions skin hydration potential 显示文摘 | Savic S Lukic M Jaksic 1 | 2011 | J ColloMInterJktce Sci2011，358，1： | 1 |
| 18 | Unified active filter and energy storage system for an MW electric vehicle charging station显示文摘 | BAI S Z LUKIC S M | 2013 | IEEE Transacions on Power Electronics2013，28，12： | 1 |
| 19 | Determination of cervicovagi- hal microorganisms in women with abnormal cervical cytology: the role of Ureaplasma urealyticum 显示文摘 | Lukic A Canzio C Patella A | 2006 | Anticancer Res2006，26，6： | 1 |
| 20 | 化妆品配方用新型表面活性剂(续完)显示文摘3.1.1.1槐糖脂
槐糖脂通过不致病的酵母菌株例如假丝酵母(Candida sp,特别是Candida bombicola)生产,尽管某些菌株如Wickerhamiella domercqiae、Pichia anomala、Rhodotorula bogoriensis也可用于生产, | 肖进新(编译) Milica Lukic Ivana Pantelic Snezana Savic | 2017 | 日用化学品科学2017，40，8： | 1 |
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