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| 1 | Genome-and transcriptome-wide association studies provide insights into the genetic basis of natural variation of seed oil content in Brassica napus显示文摘Seed oil content(SOC)is a highly important and complex trait in oil crops.Here,we decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and transcriptome-wide association studies using 505 inbred lines.We mapped reliable quantitative trait loci(QTLs)that control SOC in eight environments,evaluated the effect of each QTL on SOC,and analyzed selection in QTL regions during breeding.Six-hundred and ninety-two genes and four gene modules significantly associated with SOC were identified by analyzing population transcriptomes from seeds.A gene prioritization framework,POCKET(prioritizing the candidate genes by incorporating information on knowledge-based gene sets,effects of variants,genome-wide association studies,and transcriptome-wide association studies),was implemented to determine the causal genes in the QTL regions based on multi-omic datasets.A pair of homologous genes,BnPMT6s,in two QTLs were identified and experimentally demonstrated to negatively regulate SOC.This study provides rich genetic resources for improving SOC and valuable insights toward understanding the complex machinery that directs oil accumulation in the seeds of B.napus and other oil crops. | Shan Tang Hu Zhao Shaoping Lu Liangqian Yu Guofang Zhang Yuting Zhang Qing-Yong Yang Yongming Zhou Xuemin Wang Wei Ma Weibo Xie Liang Guo | 2021 | Molecular Plant2021，14，3： | 6 |
| 2 | Direct reprogramming of somatic cells into neural stem cells or neurons for neurological disorders显示文摘Direct reprogramming of somatic cells into neurons or neural stem cells is one of the most important frontier fields in current neuroscience research. Without undergoing the pluripotency stage, induced neurons or induced neural stem cells are a safer and timelier manner resource in comparison to those derived from induced pluripotent stem cells. In this prospective, we review the recent advances in generation of induced neurons and induced neural stem cells in vitro and in vivo and their potential treatments of neurological disorders. | Shaoping Hou Paul Lu | 2016 | Neural Regeneration Research2016，11，1： | 3 |
| 3 | Is the evolution in tumors Darwinian or non-Darwinian?显示文摘Although Darwinian selection driving the genetic diversity within tumors has been widely assumed by the field of cancer biology,recent studies that employ the rigorous tests of population genetics have increasingly suggested otherwise.In these new studies[1-5],the non-Darwinian,or neutral,model of evolution can adequately explain the documented diversities in tumors without invoking natural selection.Therefore,the half-century-old debate of selectionism vs.neutralism[6-8]on the role of natural selection in populations is | hurng-yi wang yuxin chen ding tong shaoping ling zheng hu yong tao xuemei lu chung-i wu | 2018 | National Science Review2018，5，1： | 3 |
| 4 | Transcriptional regulation of oil biosynthesis inseed plants: Current understanding, applications,and perspectives显示文摘Plants produce and accumulate triacylglycerol(TAG)in their seeds as an energy reservoir to support the processes of seed germination and seedling development.Plant seed oils are vital not only for the human diet but also as renewable feedstocks for industrial use.TAG biosynthesis consists of two major steps:de novo fatty acid biosynthesis in the plastids and TAG assembly in the endoplasmic reticulum.The latest advances in unraveling transcriptional regulation have shed light on the molecular mechanisms of plant oil biosynthesis.We summarize recent progress in understanding the regulatory mechanisms of wellcharacterized and newly discovered transcription factors and other types of regulators that control plant fatty acid biosynthesis.The emerging picture shows that plant oil biosynthesis responds to developmental and environmental cues that stimulate a network of interacting transcriptional activators and repressors,which in turn fine-tune the spatiotemporal regulation of the pathway genes. | Yuzhou Yang Que Kong Audrey R.Q.Lim Shaoping Lu Hu Zhao Liang Guo Ling Yuan Wei Ma | 2022 | Plant Communications2022，3，5： | 2 |
| 5 | Practical application and effect evaluationof notes in the practice of medical students in clinical cardiovascular department of internal medicine显示文摘 | Lu Shaoping Zhao Pinting | 2012 | Chinese herald of medicine2012，09，16： | 1 |
| 6 | A multi-instance clustering approach for Web image using one-class support vector machine 显示文摘 | Lu Jing Ma Shaoping Zhang M | 2008 | Journal of Computational Information Systems2008，4，3： | 1 |
| 7 | Quantum conductance of graphene nanoribbons with edge defects显示文摘 | Li T C Lu Shaoping | 2008 | Phys Rev B2008，77，08： | 1 |
| 8 | Effect of pre oxidation on the development of porosity in activated carbons from petroleum coke 显示文摘 | Chunlan Lu Shaoping Xu Wang Mei | 2007 | Carbon2007，45，1： | 1 |
| 9 | Effect of pre--carbonization of petroleum cokes on chemical activation process with KOH显示文摘 | Lu Chunlan Xu Shaoping Gan Yixiong Liu Shuqin and Liu Changhou | 2005 | Carbon2005，43，： | 1 |
| 10 | Quantum conductance of graphene nanoribbons with edge defects显示文摘 | Li T C Lu Shaoping | | 0，，： | 1 |
| 11 | Effect of Pre-oxidation on the Development of Porosity in Activated Carbons from Petroleum Coke 显示文摘 | LU Chunlan XU Shaoping WANG Mei | 2007 | Carbon2007，45，1： | 1 |
| 12 | Effect ofpre-carbonization of petroleum tion process with KOH 显示文摘 | Lu Chunlan Xu Shaoping Gan Yixiong | 2005 | cokes on chemical activa Carbon2005，43，11： | 1 |
| 13 | Mantle flow underneath the South China Sea revealed by seismic anisotropy显示文摘It has long been established that plastic flow in the asthenosphere interacts constantly with the overlying lithosphere and plays a pivotal role in controlling the occurrence of geohazards such as earthquakes and volcanic eruptions.Unfortunately,accurately characterizing the direction and lateral extents of the mantle flow field is notoriously difficult,especially in oceanic areas where deployment of ocean bottom seismometers(OBSs)is expensive and thus rare.In this study,by applying shear wave splitting analyses to a dataset recorded by an OBS array that we deployed between mid-2019 and mid-2020 in the South China Sea(SCS),we show that the dominant mantle flow field has a NNW-SSE orientation,which can be attributed to mantle flow extruded from the Tibetan Plateau by the ongoing Indian-Eurasian collision.In addition,the results suggest that E-W oriented flow fields observed in South China and the Indochina Peninsula do not extend to the central SCS. | Fansheng Kong Rui Gao Stephen S.Gao Kelly H.Liu Weiwei Ding Xiongwei Niu Aiguo Ruan Pingchuan Tan Jianke Fan Shaoping Lu Zhengyi Tong Liqun Cheng Wenfei Gong Yanghui Zhao Jiabiao Li | 2023 | National Science Review2023，10，10： | 0 |
| 14 | Proteome-wide identification of S-sulfenylated cysteines response to salt stress in Brassica napus root显示文摘Reactive oxygen species(ROS)play a key role in a variety of biological processes,such as the perception of abiotic stress,the integration of different environmental signals,and the activation of stress response networks.Salt stress could induce an increased ROS accumulation in plants,disrupting intracellular redox homeostasis,leading to posttranslational modifications(PTMs)of specific proteins,and eventually causing adaptive changes in metabolism.Here,we performed an iodoTMT-based proteomic approach to identify the sulfenylated proteins in B.napus root responsing to salt stress.Totally,1348 sulfenylated sites in 751 proteins were identified and these proteins were widely existed in different cell compartments and processes.Our study revealed that proteins with changed abundance and sulfenylation level in B.napus root under salt stress were mainly enriched in the biological processes of ion binding,glycolysis,ATP binding,and oxidative stress response.This study displays a landscape of sulfenylated proteins response to salt stress in B.napus root and provides some theoretical support for further understanding of the molecular mechanisms of redox regulation under salt stress in plants. | Qian Qu Xiaowei Wu Qing Zhou Shaoping Lu Xuan Yao Liang Guo Liangqian Yu | 2023 | Oil Crop Science2023，8，4： | 0 |
| 15 | A Survey on Multiview Video Synthesis and Editing显示文摘Multiview video can provide more immersive perception than traditional single 2-D video. It enables both interactive free navigation applications as well as high-end autostereoscopic displays on which multiple users can perceive genuine 3-D content without glasses. The multiview format also comprises much more visual information than classical 2-D or stereo 3-D content, which makes it possible to perform various interesting editing operations both on pixel-level and object-level. This survey provides a comprehensive review of existing multiview video synthesis and editing algorithms and applications. For each topic, the related technologies in classical 2-D image and video processing are reviewed. We then continue to the discussion of recent advanced techniques for multiview video virtual view synthesis and various interactive editing applications. Due to the ongoing progress on multiview video synthesis and editing, we can foresee more and more immersive 3-D video applications will appear in the future. | Shaoping Lu Taijiang Mu Songhai Zhang | 2016 | Tsinghua Science and Technology2016，21，6： | 0 |
| 16 | Non-specific phospholipase C4 hydrolyzes phosphosphingolipids and phosphoglycerolipids and promotes rapeseed growth and yield显示文摘Phosphorus is a major nutrient vital for plant growth and development,with a substantial amount of cellular phosphorus being used for the biosynthesis of membrane phospholipids.Here,we report that NON-SPECIFIC PHOSPHOLIPASE C4(NPC4)in rapeseed(Brassica napus)releases phosphate from phospholipids to promote growth and seed yield,as plants with altered NPC4 levels showed significant changes in seed production under different phosphate conditions.Clustered regularly interspaced short palindromic repeat(CRISPR)/CRISPR-associated nuclease 9(Cas9)-mediated knockout of Bna NPC4 led to elevated accumulation of phospholipids and decreased growth,whereas overexpression(OE)of Bna NPC4resulted in lower phospholipid contents and increased plant growth and seed production.We demonstrate that Bna NPC4 hydrolyzes phosphosphingolipids and phosphoglycerolipids in vitro,and plants with altered Bna NPC4 function displayed changes in their sphingolipid and glycerolipid contents in roots,with a greater change in glycerolipids than sphingolipids in leaves,particularly under phosphate deficiency conditions.In addition,Bna NPC4-OE plants led to the upregulation of genes involved in lipid metabolism,phosphate release,and phosphate transport and an increase in free inorganic phosphate in leaves.These results indicate that Bna NPC4 hydrolyzes phosphosphingolipids and phosphoglycerolipids in rapeseed to enhance phosphate release from membrane phospholipids and promote growth and seed production. | Bao Yang Jianwu Li Jiayu Yan Ke Zhang Zhewen Ouyang Yefei Lu Huili Wei Qing Li Xuan Yao Shaoping Lu Yueyun Hong Xuemin Wang Liang Guo | 2023 | Journal of Integrative Plant Biology2023，65，11： | 0 |
| 17 | Low-Complexity Rate Compatible Modulation with Hybrid Weight Set显示文摘Rate Compatible Modulation(RCM)is an efficient technique for high spectral efficiency seamless transmission over highly dynamic wireless channels.However,its high decoding complexity at the receiver prevents it from being applied in scenarios where computation resources are limited.To alleviate this problem,an RCM with variable weight sets(RCM-VWS)was presented in the literature to significantly reduce its complexity by employing weight sets of different complexities for channels at different signal-tonoise-ratio(SNR).However,RCM-VWS has to introduce an undesired feedback channel for the transmission of SNR information that is estimated at the receiver and transmitted back to the transmitter for weight set selection.To achieve a low computational complexity while avoiding feedback transmission at the same time,a novel RCM scheme with hybrid weight set(RCM-HWS)is introduced in this paper.A low complexity of decoding is allowed by gradually reducing the complexity of weight sets based on the number symbols already sent.It also avoids the feedback of SNRs since we can deduce SNRs from the number of the symbols transmitted and use a hybrid weight set we have designed.The theoretical analysisand simulation results show that the proposed scheme has the advantages of low demodulation complexity and not requiring feedback channel while maintaining the same transmission throughput as that of the conventional RCM.Therefore,the proposed scheme has a wider range of applications,especially in the case that feedback channel is not available. | Wengui Rao Yan Dong Shaoping Chen Fang Lu Shu Wang | 2019 | China Communications2019，16，11： | 0 |
| 18 | Commissioning experiment of the high-contrast SILEX-Ⅱ multi-petawatt laser facility显示文摘The results of a commissioning experiment on the SILEX-Ⅱlaser facility(formerly known as CAEP-PW)are reported.SILEX-Ⅱis a complete optical parametric chirped-pulse amplification laser facility.The peak power reached about 1 PWin a 30 fs pulse duration during the experiment.The laser contrast was better than 1010 at 20 ps ahead of the main pulse.In the basic laser foil target interaction,a set of experimental data were collected,including spatially resolved x-ray emission,the image of the coherent transition radiation,the harmonic spectra in the direction of reflection,the energy spectra and beam profile of accelerated protons,hot-electron spectra,and transmitted laser energy fraction and spatial distribution.The experimental results show that the laser intensity reached 531020 W/cm^(2) within a 5.8μm focus(FWHM).Significant laser transmission did not occur when the thickness of theCHfoil was equal to or greater than 50 nm.The maximum energy of the accelerated protons in the target normal direction was roughly unchanged when the target thickness varied between 50 nm and 15μm.The maximum proton energy via the target normal sheath field acceleration mechanism was about 21 MeV.We expect the on-target laser intensity to reach 10^(22) W/cm^(2) in the near future,after optimization of the laser focus and upgrade of the laser power to 3 PW. | Wei Hong Shukai He Jian Teng Zhigang Deng Zhimeng Zhang Feng Lu Bo Zhang Bin Zhu Zenghai Dai Bo Cui Yuchi Wu Dongxiao Liu Wei Qi Jinlong Jiao Faqiang Zhang Zuhua Yang Feng Zhang Bi Bi Xiaoming Zeng Kainan Zhou Yanlei Zuo Xiaojun Huang Na Xie Yi Guo Jingqin Su Dan Han Ying Mao Leifeng Cao Weimin Zhou Yuqiu Gu Feng Jing Baohan Zhang Hongbo Cai Minqing He Wudi Zheng Shaoping Zhu Wenjun Ma Dahui Wang Yinren Shou Xueqing Yan Bin Qiao Yi Zhang Congling Zhong Xiaohui Yuan and Wenqing Wei | 2021 | Matter and Radiation at Extremes2021，6，6： | 0 |
| 19 | Preliminary Results of the Seismicity Monitoring Experiment around the 2019 Mw5.4 Earthquake Epicenter in the Central South China Sea Basin显示文摘On September 5,2019,a moderate earthquake of Mw5.4 unexpectedly occurred in the apparently quiescent central basin of the South China Sea.We immediately carried out a seismicity monitoring experiment around the epicenter by using broadband ocean bottom seismometers(OBS)for the following three scientific targets.The first is knowing the earthquake seismogenic mechanism,fault structure and further development.The second is finding the role of the residual spreading ridge playing in earthquake processes and further revealing the deep structures of the ridge directional turning area.The third is confirming the existence and significance of the so called“Zhongnan fault”.This paper reports the preliminary results of the first phase experiment.Five OBSs were deployed for seismicity monitoring with a duration of 288 days,but only three were recovered.Micro-earthquakes were firstly detected by an automatic seismic phase picking algorithm and then were verified by analyzing their seismic phases and time-frequency characteristics in detail.A total of 21,68 and 89 microearthquakes were picked out from the three OBSs respectively within the distance of 30 km.The dominant frequency of these micro-earthquakes is 12-15 Hz,indicating tectonic fracturing.During the first two months after the mainshock the seismicity was relatively stronger,and micro-earthquakes were still occurring occasionally till the end of observation,indicating the epicenter area is active.We used Match&Locate method to locate 57 micro-earthquakes preliminarily.Their spatial distribution shows that the seismicity is developed mainly along the NE direction roughly parallel to the residual ridge with depth variations between 10-20 km. | Wenfei Gong Aiguo Ruan Xiongwei Niu Zhenjie Wang Pingchuan Tan Xiaodong Wei Wei Wang Zhengyi Tong Liqun Cheng Fansheng Kong Shaoping Lu Jianke Fan Weiwei Ding Jinyao Gao Chunguo Yang Jiabiao Li | 2024 | Journal of Earth Science2024，35，1： | 0 |
| 20 | Functional genomics of Brassica napus:Progresses,challenges,and perspectives显示文摘Brassica napus,commonly known as rapeseed or canola,is a major oil crop contributing over 13%to the stable supply of edible vegetable oil worldwide.Identification and understanding the gene functions in the B.napus genome is crucial for genomic breeding.A group of genes controlling agronomic traits have been successfully cloned through functional genomics studies in B.napus.In this review,we present an overview of the progress made in the functional genomics of B.napus,including the availability of germplasm resources,omics databases and cloned functional genes.Based on the current progress,we also highlight the main challenges and perspectives in this field.The advances in the functional genomics of B.napus contribute to a better understanding of the genetic basis underlying the complex agronomic traits in B.napus and will expedite the breeding of high quality,high resistance and high yield in B.napus varieties. | Zengdong Tan Xu Han Cheng Dai Shaoping Lu Hanzi He Xuan Yao Peng Chen Chao Yang Lun Zhao Qing-Yong Yang Jun Zou Jing Wen Dengfeng Hong Chao Liu Xianhong Ge Chuchuan Fan Bing Yi Chunyu Zhang Chaozhi Ma Kede Liu Jinxiong Shen Jinxing Tu Guangsheng Yang Tingdong Fu Liang Guo Hu Zhao | 2024 | Journal of Integrative Plant Biology2024，66，3： | 0 |
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