|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A general-purpose machine learning framework for predicting properties of inorganic materials显示文摘A very active area of materials research is to devise methods that use machine learning to automatically extract predictive models from existing materials data.While prior examples have demonstrated successful models for some applications,many more applications exist where machine learning can make a strong impact.To enable faster development of machine-learning-based models for such applications,we have created a framework capable of being applied to a broad range of materials data.Our method works by using a chemically diverse list of attributes,which we demonstrate are suitable for describing a wide variety of properties,and a novel method for partitioning the data set into groups of similar materials to boost the predictive accuracy.In this manuscript,we demonstrate how this new method can be used to predict diverse properties of crystalline and amorphous materials,such as band gap energy and glass-forming ability. | Logan Ward Ankit Agrawal Alok Choudhary Christopher Wolverton | 2016 | npj Computational Materials2016，，1： | 83 |
| 2 | Cell Wall, Cytoskeleton, and Cell Expansion in Higher Plants显示文摘在植物生理学提供二个看起来矛盾的生物角色,提供僵硬结构的 supportof 植物房间和可调节的弹性为房间扩大需要,植物房间墙的作文让 evolvedto 成为一个复杂网络有纤维质, hemicellulosic,和果胶的多糖和蛋白质。由于它的复杂性,房间墙影响的许多方面种房间扩大,和新的许多和深刻观察和技术 areforthcoming。房间墙聚合物的生合成和涉及要描绘的多糖 synthesiscontinue 的蛋白质的变化的角色。在房间墙聚合物网络和植物房间墙怎么提供它的双函数的这些 interactionsprovide 卓见的修正以内的相互作用。复杂房间墙建筑学是动态细胞内部的细胞骨架并且由房间墙 polymersand 房间的多样的 trafficking 小径部分地组织的 controlledand 墙相关的机械。同时,房间墙不断地被影响由神经质并且察觉到 stimulithat 的正直被房间察觉。这些许多过程合作,维持,并且操作为支撑工厂身高,生长,和 life.Key 词的复杂 plantcell wallan 必需品结构到构造: | Logan Bashline Lei Lei Shundai Li Ying Gu | 2014 | Molecular Plant2014，7，4： | 11 |
| 3 | 心力衰竭患者中持续气道正压通气抑制中枢性睡眠呼吸暂停与未实施心脏移植存活率的关系:一项对CANPAP试验的事后分析显示文摘背景:在CANPAP[加拿大中枢性睡眠呼吸暂停(CSA)合并心力衰竭患者经持续气道正压通气(CPAP)治疗]试验的主要分析中,CPAP对患者的未实施心脏移植存活率无影响;然而,CPAP仅使平均呼吸暂停低通气指数降至睡眠期间19次/h。 | Arzt M. Floras J.S. Logan A.G. T.D. Bradley 刘相飞 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，，11： | 7 |
| 4 | Driver mutations of cancer epigenomes显示文摘Epigenetic 改变与癌症的所有方面被联系,从肿瘤开始到癌症前进和转移。DNA methylation 以及改变的染色质组织的损失和获得显著地作出贡献到联系癌症的显型,这现在很好被理解。更最近,新定序技术在 epigenetic 管理者允许司机变化的鉴定,提供在癌症 epigenome 和基因改变之间的一个机械学的连接。激活变化的 Oncogenic 现在被知道发生在很多个 epigenetic 修饰词(即 IDH1/2, EZH2, DNMT3A ) ,指出涉及 tumorigenesis 的 epigenetic 小径。同样,调查进在染色质修饰词使变化失去活性的角色(即 KDM6A, CREBBP/EP300, SMARCB1 ) 含有许多这些基因作为肿瘤 suppressors。有趣地,很多个瘤被变化的过多在 epigenetic 管理者定义,包括肾,膀胱,和 adenoid 膀胱的癌。特别地罢工是在小儿科的 glioma 的经常的 histone H3.3 变化的发现,长糟糕留下了的一个特别地好攻击的瘤理解。癌症 epigenetics 是有为改进癌症结果的许多潜力的相对新的、有希望的边疆。已经,象 5-azacytidine 和 decitabine 那样的治疗证明了在癌症指向 epigenetic 改变能导致有形的好处。理解基因改变怎么产生癌症 epigenome 将为开发更好预示、治疗学的策略提供新可能性。 | David M. Roy Logan A. Walsh Timothy A. Chan | 2014 | Protein & Cell2014，5，4： | 7 |
| 5 | THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE显示文摘 | Catriona Y. Logan Roel Nusse | 2004 | Annual Review of Cell and Developmental Biology2004，，： | 6 |
| 6 | 稀土Nd改性纳米TiO2-NTs/SnO2-Sb电极的制备、结构及性能显示文摘采用溶剂热法制备了稀土Nd掺杂TiO_2-NTs/SnO_2-Sb电极,以苯酚作为典型有机物,考察了电极组成、结构与电极电催化效能的关系,实验结果表明,Nd的掺杂量对电极电催化性能有较大的影响,当前驱液中Nd/Sn原子摩尔百分比为3%时,电极的电催化活性最佳,对苯酚浓度及TOC的降解速率较空白电极(Nd0%)提高了60%及52%。利用SEM及XRD分析方法对所制备的电极进行了形貌及晶形结构的表征,并计算了电极表面SnO_2晶胞参数以及平均粒径,结果显示,适量地掺杂Nd元素后,电极表面更加致密,SnO_2平均粒径变小。通过XPS分析电极表面元素组成,并计算电极表面吸附氧含量,结果表明,由于Nd元素的存在,降低了涂层中晶格氧(O_(lat))的含量,减弱了电子的吸引作用,促使了Sn^(4+)周围电子云密度升高,从而电极表面Sn元素特征衍射峰表现为向低结合能方向偏移。与空白电极(Nd0%)相比,改性后的电极(Nd3%)涂层表面Sb含量下降,且吸附氧(O_(ads))含量上升,为空白电极的1.6倍。EPR测试结果进一步证实了改性后电极性能提高的机制,Nd元素的引入,增加了电极涂层表面氧空位的浓度,使得电极涂层表面各元素的化学环境发生改变。掺杂改性后,电极的析氧电位以及产羟基自由基能力均得以提升,从而促使电极催化活性大大增强。 | 杨莉莎 刘俊峰 黄琳琳 郭嘉钰 冯玉杰 LOGAN Bruce | 2018 | 环境工程学报2018，12，8： | 6 |
| 7 | Amalgamated gold-nanoalloys with enhanced catalytic activity for the detection of mercury ions(Hg^2+)in seawater samples显示文摘Mercury(Hg)is extremely toxic,and continues to cause major threats to aquatic life,human health and the environment.Hg^2+mainly derives from seawater as a product of atmospheric deposition,therefore there is great demand for sensing approaches that can detect Hg^2+in seawater samples.Herein,we demonstrate that the peroxidase-mimicking activity of gold nanoparticles(AuNPs)or so-called nanozymes,can be exploited for the detection of Hg^2+ions in various water samples.In a high electrolyte environment,the catalytic activity for the oxidation of 3,3’,5,5’-tetramethylbenzidine(TMB)was significantly diminished due to poor stability of the bare-AuNPs.This activity was reduced by-73.7%when the NaCl concentration was higher than 1.168%,which is much lower than that of seawater(-3.5%),thus presenting its unsuitability for detecting Hg^2+in harsh water matrices.To overcome this limitation,AuNPs were first functionalized with oligo-ethylene glycol(OEG),of which their colloidal form presented high stability in NaCl concentrations up to 20%and across a wide range of pHs from 1-14.Interestingly,the catalytic activity of OEG-AuNPs for the oxidation of TMB was strongly suppressed by the coating,but enhanced upon formation of Au-Hg amalgamation.This novel finding underlies a straightforward,sensitive,and highly selective detection platform for Hg^2+in water samples.The approach could detect the exposure limit level for Hg^2+in drinking water(i.e.,2 ppb for tap and bottled water)as set by the United States Environmental Protection Agency(EPA)and the World Health Organization(WHO).When Hg^2+was spiked into a 3.5%saline solution and a coastal seawater certified reference material(CRM),the detection limits were found to be 10 ancM 3 ppb,respectively,which exceed the Hg^2+concentrations commonly found within seawater(-60-80 ppb).The whole procedure takes less than 45 min to conduct,providing a highly innovative,rapid and low-cost approach for detecting Hg^2+in complex water matrices. | Natasha Logan Claire McVey Christopher Elliott Cuong Cao | 2020 | Nano Research2020，13，4： | 6 |
| 8 | Unusual switchable peroxidase-mimicking nanozyme for the determination of proteolytic biomarker显示文摘Detection of enzyme biomarkers originating from either bio-fluids or contaminating microorganisms is of utmost importance in clinical diagnostics and food safety. Herein, we present a simple, low-cost and easy-to-use sensing approach based on the switchable peroxidase-mimicking activity of plasmonic gold nanoparticles (AuNPs) that can catalyse for the oxidation of 3,3’,5’5-tetramethylbenzidine (TMB) for the determination of protease enzyme. The AuNP surface is modified with casein, showing dual functionalities. The first function of the coating molecule is to suppress the intrinsic peroxidase-mimicking activity of AuNPs by up to 77.1%, due to surface shielding effects. Secondly, casein also functions as recognition sites for the enzyme biomarker. In the presence of protease, the enzyme binds to and catalyses the degradation of the coating layer on the AuNP surface, resulting in the recovery of peroxidase-mimicking activity. This is shown visually in the development of a blue colored product (oxidised TMB) or spectroscopically as an increase in absorbance at 370 and 650 nm. This mechanism allows for the detection of protease at 44 ng·mL^-1 in 90 min. The nanosensor circumvents issues associated with current methods of detection in terms of ease of use, compatibility with point-of-care testing, low-cost production and short analysis time. The sensing approach has also been applied for the detection of protease spiked in ultra-heat treated (UHT) milk and synthetic human urine samples at a limit of detection of 490 and 176 ng·mL^-1, respectively, showing great potential in clinical diagnostics, food safety and quality control. | Claire McVey Natasha Logan Nguyen T. K. Thanh Christopher Elliott Cuong Cao | 2019 | Nano Research2019，12，3： | 5 |
| 9 | Decorin treatment of spinal cord injury显示文摘The scarring response after a penetrant central nervous system injury results from the interaction between invading leptominingeal/pericyte-derived fibroblasts and endogenous reactive astrocytes about the wound margin. Extracellular matrix and scar-derived axon growth inhibitory molecules fill the lesion site providing both a physical and chemical barrier to regenerating axons. Dec orin, a small leucine-rich chondroitin-dermatan sulphate proteoglycan expressed by neurons and astrocytes in the central nervous system, is both anti-fibrotic and anti-inflammatory and attenuates the formation and partial dissolution of established and chronic scars. Here, we discuss the potential of using Decorin to antagonise scarring in the central nervous system. | Maryam Esmaeili Martin Berry Ann Logan Zubair Ahmed | 2014 | Neural Regeneration Research2014，9，18： | 5 |
| 10 | Assessment of the anterior spinal artery and the artery of Adamkiewicz using multi-detector CT angiography显示文摘在下降的治疗以后的针的绳索的背景损坏胸并且 thoracoabdominal 大动脉的动脉瘤是不平常却破坏的复杂并发症。Adamkiewicz 的动脉(也称为) 在更低的胸、腰部的水平是前面的针的动脉(ASA ) 的主要动脉的供应。这研究的目的是评估前面的针的动脉和 Adamkiewicz 的动脉的可视化,为用多察觉者的察觉率的影响因素划 CT (MDCT ) 。方法 99 个连续病人(31 个女人和 68 个男人;年龄范围, 25-90 年;平均年龄 61.3 年) 为要求外科的干预(31 大动脉的动脉瘤, 45 解剖, 5 内部 hematoma,和 18 正常) 的胸的大动脉的损害的怀疑地,从大动脉的拱门经历了 CT angiography 到大动脉的分叉。横向的节, multiplanar 改革和薄最大的紧张设计被用来估计 ASA 并且也称为。ASA 并且也称为起源和 CT 获得参数的水平被记录。图象, T11 身体(脊椎的集体索引) 的团的一个索引,下的胖厚度,和在大动脉的拱门以内并且在 T11 水平的 CT 值的 contrast-to-noise 比率被测量。ASA 并且也称为的察觉相对获得参数,扫描特征,和大动脉的损害类型被评估。差别与 Wilcoxon 等级和和 t 测试被估计。结果 ASA 在 18 个病人(18%) 在 51 个病人(52%) 和 AKA 被设想。ASA 与 2.5-3.0 公里厚度与 1.25 公里厚度并且在 15/32 病人(47%) 在 36/67 病人(54%) 被识别。这差别没完成意义(P=0.13 ) 。ASA 和 AKA 的察觉率被脊椎的集体索引和 contrast-to-noise 比率影响(P < 0.05 ) 。下的脂肪的数量影响了 ASA 的察觉率(P < 0.05 ) 然而并非 AKA。在 ASA 察觉的 CT 扫描,分别地,而,在在拱门并且在 T11 的主动脉的吝啬的 CT 价值是 360 和 358 胡在没有 ASA 察觉的 CT 扫描,在在拱门并且在 T11 的主动脉的 CT 价值更低( P < 0.05 ), 297 和 317 胡, respectively.Conclusions ASA 并且也称为不太经常比以前的报告在我们的队被检测。ASA 并且也称为的可视化被大动脉的改进显著地影响, =vertebral 团索引“,并且 contrast-to-noise 比率。 | ZHAO Shao-hong, Laura Logan Pamela Schraedley Geoffrey D. Rubin | 2009 | Chinese Medical Journal2009，，2： | 5 |
| 11 | Monitoring Crustal Deformation by GPS and InSAR in the Three Gorge Area显示文摘The on going Three Gorges Project (TGP) aims to build one of the largest hydropower stations in the world. Previous investigations have concluded that the reservoir is likely to induce medium to intense earthquakes. 23 GPS stations have been established to maintain a geodetic and seismological monitoring network around the reservoir to monitor seismicity and crustal deformation, and to facilitate mitigation activities in case an intense earthquake occurs. The velocity of GPS site was derived from 3 repeated GPS surveys. Meanwhile, another effort has been made to investigate the feasibility of application of satellite interferometric synthetic aperture radar (InSAR) techniques in detecting crustal deformation possibly caused by impoundment of the Three Gorges Reservoir. It has been made to derive digital elevation models (DEM) using European Remote Sensing (ERS) synthetic aperture radar (SAR) imagery. Pairs of ERS SAR images in raw format are processed to generate digital elevation models. This effort will help us evaluate the accuracy of the InSAR techniques for further derivation of background deformation patterns and future detection of reservoir induced crustal deformation in the area. | Qiao Xue-jun Li Shu-sun You Xin-zhao Du Rui-lin Tom Logan | 2002 | Wuhan University Journal of Natural Sciences2002，7，4： | 4 |
| 12 | Decorin treatment for reversing trabecular meshwork fibrosis in open-angle glaucoma显示文摘In this perspective,we discuss the use of an anti-fibrotic agent Decorin to treat established fibrosis associated with glaucoma originally published by Hill et al.(2015).Glaucoma describes a group of progressive optic neuropathies that have the potential to cause irreversible blindness,for | Lisa J Hill Zubair Ahmed Ann Logan | 2016 | Neural Regeneration Research2016，11，6： | 3 |
| 13 | The fit of Industry 4.0 applications in manufacturing logistics: a multiple case study显示文摘 | Jo Wessel Strandhagen Erlend Alfnes Jan Ola Strandhagen Logan Reed Vallandingham | 2017 | Advances in Manufacturing2017，5，4： | 3 |
| 14 | Exercise interventions for older adults: A systematic review of meta-analyses显示文摘Background:The evidence concerning which physical exercise characteristics are most effective for older adults is fragmented.We aimed to characterize the extent of this diversity and inconsistency and identify future directions for research by undertaking a systematic review of metaanalyses of exercise interventions in older adults.Methods:We searched the Cochrane Database of Systematic Reviews,PsycInfo,MEDLINE,Embase,CINAHL,AMED,SPORTDiscus,and Web of Science for articles that met the following criteria:(1)meta-analyses that synthesized measures of improvement(e.g.,effect sizes)on any outcome identified in studies of exercise interventions;(2)participants in the studies meta-analyzed were adults aged 65+or had a mean age of 70+;(3)meta-analyses that included studies of any type of exercise,including its duration,frequency,intensity,and mode of delivery;(4)interventions that included multiple components(e.g.,exercise and cognitive stimulation),with effect sizes that were computed separately for the exercise component;and(5)meta-analyses that were published in any year or language.The characteristics of the reviews,of the interventions,and of the parameters improved through exercise were reported through narrative synthesis.Identification of the interventions linked to the largest improvements was carried out by identifying the highest values for improvement recorded across the reviews.The study included 56 meta-analyses that were heterogeneous in relation to population,sample size,settings,outcomes,and intervention characteristics.Results:The largest effect sizes for improvement were found for resistance training,meditative movement interventions,and exercise-based active videogames.Conclusion:The review identified important gaps in research,including a lack of studies investigating the benefits of group interventions,the characteristics of professionals delivering the interventions associated with better outcomes,and the impact of motivational strategies and of significant others(e.g.,carers)on intervention delivery and outcomes. | Claudio Di Lorito Annabelle Long Adrian Byrne Rowan H.Harwood John R.F.Gladman Stefan Schneider Pip Logan Alessandro Bosco Veronika van der Wardt | 2021 | Journal of Sport and Health Science2021，10，1： | 3 |
| 15 | Collecting the newborn screening test(NST),via the heel prick显示文摘 | Logan P | 1997 | J Aust Coll Midwives1997，10，： | 2 |
| 16 | Electricity generation using membrane and salt bridge microbial fuel cells显示文摘 | Booki Min Shaoan Cheng Bruce E. Logan | 2005 | Water Research2005，，9： | 2 |
| 17 | Healing of duodenal ulcer after eradication of Helicobacter heilmannii显示文摘 | Andrew F Goddard Robert PH Logan John C Atherton David Jenkins Robin C Spiller | 1997 | The Lancet1997，，9068： | 2 |
| 18 | The similarity between human embryonic stem cell-derived epithelial cells and ameloblast-lineage cells显示文摘This study aimed to compare epithelial cells derived from human embryonic stem cells (hESCs) to human ameloblast-lineage cells (ALCs), as a way to determine their potential use as a cell source for ameloblast regeneration. Induced by various concentrations of bone morphogenetic protein 4 (BMP4), retinoic acid (RA) and lithium chloride (LiCI) for 7 days, hESCs adopted cobble-stone epithelial phenotype (hESC-derived epithelial cells (ES-ECs)) and expressed cytokeratin 14. Compared with ALCs and oral epithelial cells (OE), ES-ECs expressed amelogenesis-associated genes similar to ALCs. ES-ECs were compared with human fetal skin epithelium, human fetal oral buccal mucosal epithelial cells and human ALCs for their expression pattern of cytokeratins as well. ALCs had relatively high expression levels of cytokeratin 76, which ,vas also found to be upregulated in ES-ECs. Based on the present study, with the similarity of gene expression with ALCs, ES-ECs are a promising potential cell source for regeneration, which are not available in erupted human teeth for regeneration of enamel. | Li-Wei Zheng Logan Linthicum Pamela K DenBesten Yan Zhang | 2013 | International Journal of Oral Science2013，5，1： | 2 |
| 19 | 脑瘫和社会经济学状况:一个回顾性队列研究 | Sundrum R. Logan S. Wallace A. Spencer N. 贺莉 | 2005 | 世界核心医学期刊文摘(儿科学分册)2005，0，5： | 2 |
| 20 | Dental pulp stem cells, a paracrine-mediated therapy for the retina显示文摘The functional loss that occurs after retinal/optic nerve injury is permanent and can arise through trauma or neurodegenerative conditions such as glaucoma.Neurotrophic factors(NTFs)promote survival of injured retinal ganglion cells(RGCs)and regeneration of their axons。 | Ben Mead Ann Logan Martin Berry Wendy Leadbeater Ben A. Scheven | 2014 | Neural Regeneration Research2014，9，6： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员