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| 1 | Spinal Cord Stimulation for Pain Treatment After Spinal Cord Injury显示文摘In addition to restoration of bladder, bowel, and motor functions, alleviating the accompanying debilitating pain is equally important for improving the quality of life of patients with spinal cord injury(SCI). Currently,however, the treatment of chronic pain after SCI remains a largely unmet need. Electrical spinal cord stimulation(SCS) has been used to manage a variety of chronic pain conditions that are refractory to pharmacotherapy. Yet, its efficacy, benefit profiles, and mechanisms of action in SCI pain remain elusive, due to limited research, methodological weaknesses in previous clinical studies, and a lack of mechanistic exploration of SCS for SCI pain control. We aim to review recent studies and outline the therapeutic potential of different SCS paradigms for traumatic SCI pain. We begin with an overview of its manifestations,classification, potential underlying etiology, and currentchallenges for its treatment. The clinical evidence for using SCS in SCI pain is then reviewed. Finally, future perspectives of pre-clinical research and clinical study of SCS for SCI pain treatment are discussed. | Qian Huang Wanru Duan Eellan Sivanesan Shuguang Liu Fei Yang Zhiyong Chen Neil C.Ford Xueming Chen Yun Guan | 2019 | Neuroscience Bulletin2019，35，3： | 13 |
| 2 | Microstructure and electrical properties of Y_2O_3-doped ZnO-based varistor ceramics prepared by high-energy ball milling显示文摘Y2O3-doped ZnO-based varistor ceramics were prepared using high-energy ball milling (HEBM) and low-temperature sin- tering technique, with voltage-gradient of 1934-2197 V/mm, non-linear coefficients of 20.8-21.8, leakage currents of 0.59-1.04 μA, and densities of 5.46-5.57 g/cm3. With increasing Y2O3 content, the voltage-gradient increases because of the decrease of ZnO grain size; the non-linear coefficient and the leakage current improve but the density decreases because of more porosity; the donor con- centration and density of interface states decrease, whereas the barrier height and width increase because of the acceptor effect of Y2O3 in varistor ceramics. | Hongyu Liu Xueming Ma Dongmei Jiang Wangzhou Shi | 2007 | Journal of University of Science and Technology Beijing2007，14，3： | 13 |
| 3 | Revealing the behavior of soliton buildup in a mode-locked laser显示文摘Real-time spectroscopy based on an emerging time-stretch technique can map the spectral information of optical waves into the time domain,opening several fascinating explorations of nonlinear dynamics in mode-locked lasers.However,the self-starting process of mode-locked lasers is quite sensitive to environmental perturbation,which causes the transient behaviors of lasers to deviate from the true buildup process of solitons.We optimize the laser system to improve its stability,which suppresses the Q-switched lasing induced by environmental perturbation.We,therefore,demonstrate the first observation of the entire buildup process of solitons in a mode-locked laser,revealing two possible pathways to generate the temporal solitons.One pathway includes the dynamics of raised relaxation oscillation,quasimode-locking stage,spectral beating behavior,and finally the stable single-soliton mode-locking.The other pathway contains,however,an extra transient bound-state stage before the final single-pulse modelocking operation.Moreover,we propose a theoretical model to predict the buildup time of solitons,which agrees well with the experimental results.Our findings can bring real-time insights into ultrafast fiber laser design and optimization,as well as promote the application of fiber laser. | Xueming Liu Yudong Cui | 2019 | Advanced Photonics2019，1，1： | 9 |
| 4 | Assimilating operational SST and sea ice analysis data into an operational circulation model for the coastal seas of China显示文摘The prediction of sea surface temperature(SST) is an essential task for an operational ocean circulation model. A sea surface heat flux, an initial temperature field, and boundary conditions directly affect the accuracy of a SST simulation. Here two quick and convenient data assimilation methods are employed to improve the SST simulation in the domain of the Bohai Sea, the Yellow Sea and the East China Sea(BYECS). One is based on a surface net heat flux correction, named as Qcorrection(QC), which nudges the flux correction to the model equation; the other is ensemble optimal interpolation(En OI), which optimizes the model initial field. Based on such two methods, the SST data obtained from the operational SST and sea ice analysis(OSTIA) system are assimilated into an operational circulation model for the coastal seas of China. The results of the simulated SST based on four experiments, in 2011, have been analyzed. By comparing with the OSTIA SST, the domain averaged root mean square error(RMSE) of the four experiments is 1.74, 1.16, 1.30 and 0.91°C, respectively; the improvements of assimilation experiments Exps 2, 3 and 4 are about 33.3%, 25.3%, and 47.7%, respectively.Although both two methods are effective in assimilating the SST, the En OI shows more advantages than the QC,and the best result is achieved when the two methods are combined. Comparing with the observational data from coastal buoy stations, show that assimilating the high-resolution satellite SST products can effectively improve the SST prediction skill in coastal regions. | JI Qiyan ZHU Xueming WANG Hui LIU Guimei GAO Shan JI Xuanliang XU Qing | 2015 | Acta Oceanologica Sinica2015，34，7： | 7 |
| 5 | Solitons in the fractional Schr?dinger equation with parity-time-symmetric lattice potential显示文摘We investigate the properties of spatial solitons in the fractional Schr?dinger equation(FSE) with parity-time(PT)-symmetric lattice potential supported by the focusing of Kerr nonlinearity. Both one-and two-dimensional solitons can stably propagate in PT-symmetric lattices under noise perturbations. The domains of stability for both one-and two-dimensional solitons strongly depend on the gain/loss strength of the lattice. In the spatial domain, the solitons are rigidly modulated by the lattice potential for the weak diffraction in FSE systems. In the inverse space, due to the periodicity of lattices, the spectra of solitons experience sharp peaks when the values of wavenumbers are even. The transverse power flows induced by the imaginary part of the lattice are also investigated, which can preserve the internal energy balances within the solitons. | XIANKUN YAO XUEMING LIu | 2018 | Photonics Research2018，6，9： | 6 |
| 6 | Numerical study and prediction of nuclear contaminant transport from Fukushima Daiichi nuclear power plant in the North Pacific Ocean显示文摘On March 11,2011,a large earthquake and subsequent tsunami near the east coast of Japan destroyed the Fukushima Daiichi nuclear power plant(FD-NPP),causing a massive release of nuclear contaminants.In this paper,a Pacific basin-wide physical dispersion model is developed and used to investigate the transport of nuclear contaminants.The Pacific circulation model,based on the Regional Ocean Modeling System(ROMS),is forced with air-sea flux climatology derived from COADS(the Comprehensive Ocean-Atmosphere Data Set).It is shown that ocean current dominates nuclear contaminant transport.Following the Kuroshio Extension and North Pacific Current,nuclear contaminants at the surface will move eastward in the Pacific as far as 140°W,thereafter dividing into two branches.For the south branch,nuclear contaminants will be transported westward by the equatorial current,and can reach the Philippines after 10 years' time.In contrast,the north branch will arrive at the American west coast and then migrate to the Bering Sea.At 200 m water depth,part of the nuclear materials will move southwestward along with deep ocean circulation,which could potentially reach the east coast of Taiwan.The other part will move to the west coast of America and separate into two branches.One will move northward along the west coast of Alaska,while the other will travel southward to the Hawaiian Islands.The transport of radiation contaminants below 500 m is slow,and will primarily remain in the central Pacific.The physical dispersion model results show that high concentrations of the radioactive isotope cesium-137(137 Cs) will move eastward and reach the central Pacific and west coast of North America in two and eight years,respectively.The sea areas influenced by the nuclear contaminants continue to expand,while peak concentrations decrease in the North Pacific. | WANG Hui WANG ZhaoYi ZHU XueMing WANG DaKui LIU GuiMei | 2012 | Chinese Science Bulletin2012，57，26： | 6 |
| 7 | Amyloid fibril structure of α-synuclein determined by cryo- electron microscopy显示文摘 | Yaowang Li Chunyu Zhao Feng LUO Zhenying Liu Xinrui Gui Zhipu LUO Xiang Zhang Dan Li Cong Liu Xueming Li | 2018 | Cell Research2018，28，9： | 5 |
| 8 | Development and validation of an analytical method for detecting chlorantraniliprole residues in fresh tea leaves显示文摘An efficient method using multiwalled carbon nanotubes(MWCNTs)as dispersive solid-phase extraction sorbent was established for determining chlorantraniliprole residues in fresh tea leaves,which are known to be a troublesome matrix containing abundant pigments,via gas chromatography with an electron capture detector.Acetonitrile was used as the extraction solvent,with sodium chloride enhancing the analyte partition in the organic phase.The optimal mixture of MWCNTs and primary secondary amine(PSA)was based on the distribution of the target analyte recovery and on the clean-up efficiency;while matrix-matched calibration was recommended to combat the matrix effect.Mean recoveries of 95.2%–108.8%were obtained with intraday and interday precisions of less than 7.9%and 10.3%,respectively.Good linearity was observed for concentrations of 0.02–1.0 mg/kg with a correlation coefficient of 0.9984.The limits of detection and quantification were 0.005 mg/kg and 0.02 mg/kg,respectively.The method was employed to investigate the dissipation dynamics of chlorantraniliprole in fresh tea leaves with real field samples.Consequently,the dissipation rates of chlorantraniliprole in fresh tea leaves followed pseudo-first-order kinetics with a half-life of 1.9 d,and the average chlorantraniliprole residue content was below 0.02 mg/kg with a harvest withholding period of 14 d. | Tengfei Liu Minghui Dong Fengjie Zhou Daifeng Yang Xueming Zhang | 2019 | Food Science and Human Wellness2019，8，4： | 5 |
| 9 | Investigation of Amorphization of Nb-Si Alloys by Mechanical Alloying显示文摘Amorphous Nb_(62.5)Si_(37.5) and Nb_(75)Si_(25) alloys were produced from mixtures of elemental Nb and Si powders by mechanical alloying(MA).The structural changes of mechanically alloyed powders were monitored by x-ray diffraction.It was found that NbSi_(2),intermetallic compound was formed in the initial stage of MA of or Nb_(62.5)Si_(37.5) or Nb_(75)Si_(25) powders.With continued milling,the mixtures of intermetallic NbSi_(2) and elemental Nb transformed into amorphous Nb-Si alloys(Nb_(62.5)Si_(37.5) or Nb_(75)Si_(25)).The slow interdiffusion of Nb and Si and the slower diffusion of silicon atoms to niobium matrix than that of niobium atoms to silicon matrix were suggested to be responsible for the formation of intermetallic NbSi_(2).The amorphization of 3NbSi_(2)+7Nb mixtures(or NbSi_(2)+5Nb mixtures)is believed to be controlled by material transfer,which moves composition of line intermetallic NbSi2 off stoichiometry,and causes the matrix of elemental Nb deformed. | LI Bing MA Xueming LIU Lin QI Zhenzhong DONG Yuanda | 1994 | Chinese Physics Letters1994，11，11： | 4 |
| 10 | Effects of cooling rate on the microstructure and electrical properties of Dy_2O_3-doped ZnO-based varistor ceramics显示文摘The microstructure, electrical properties, and density of Dy2O3-doped ZnO-based varistor ceramics, prepared us-ing high-energy ball milling (HEBM) and sintered at 800°C, were investigated by increasing the cooling rate in the order of H (slow cooling in furnace) → L (cooling in furnace) → K (cooling in air). With the increase in cooling rate, the grain size and density decreased, the breakdown voltage (V1 mA / mm) increased, and the nonlinear coefficient (α) and leakage current (IL) exhibited extremum. The sample with the cooling type L showed the best properties with the breakdown voltage of 2650 V/mm, α of 20.3, IL of 5.2 μA, and density of 5.42 g/cm3. The barrier height (φB), donor concentration (Nd), density of the interface states (Ns), and barrier width (ω) all exhibited extremum during the alteration in cooling rate. The different relative amount of Bi-rich phase and its distribution as well as the characteristic parameters of grain boundary, resulting from the alteration of cooling rate, led to the changes in the properties of varistor ceramics. | LIU Hongyu KONG Hui JIANG Dongmei SHI Wangzhou MA Xueming ZHANG Huining | 2007 | Rare Metals2007，26，1： | 4 |
| 11 | Revelation of the birth and extinction dynamics of solitons in SWNT-mode-locked fiber lasers显示文摘The dispersive Fourier transform(DFT) technique opens a fascinating pathway to explore ultrafast non-repetitive events and has been employed to study the build-up process of mode-locked lasers. However, the shutting process for the mode-locked fiber laser seems to be beyond the scope of researchers, and the starting dynamics under nearzero dispersion remains unclear. Here, the complete evolution dynamics(from birth to extinction) of the conventional soliton(CS), stretched pulse(SP), and dissipative soliton(DS) are investigated by using the DFT technique.CS, SP, and DS fiber lasers mode locked by single-walled carbon nanotubes(SWNTs) are implemented via engineering the intracavity dispersion map. The relaxation oscillation can always be observed before the formation of stable pulse operation due to the inherent advantage of SWNT, but it exhibits distinct evolution dynamics in the starting and shutting processes. The shutting processes are dependent on the dispersion condition and turn-off time, which is against common sense. Some critical phenomena are also observed, including transient complex spectrum broadening and frequency-shift interaction of SPs and picosecond pulses. These results will further deepen understanding of the mode-locked fiber laser from a real-time point of view and are helpful for laser design and applications. | YUDONG CUI XUEMING LIU | 2019 | Photonics Research2019，7，4： | 4 |
| 12 | Elucidating the various multi-phosphorylation statuses of protein functional regions by 193-nm ultraviolet photodissociation显示文摘Ultraviolet photodissociation is a high-energy fast excitation method in mass spectrometry and has been successfully applied for the elucidation of sequences and structures of biomolecules. However, its ability to distinguish the phosphorylation sites isomers of multi-phosphopeptides has been not systematically investigated until now. A 193-nm ultraviolet laser dissociation mass spectrometry system was established in this study and applied to elucidate the complex multi-phosphorylation statuses mimicking the functional regions of Sic1, Gli3 and Tau. The numbers of matched fragment ions and phosphorylation site-determining ions were improved on average 123% and 104%, respectively, by utilizing the ultraviolet photodissociation strategy, comparing to the typically utilized collision induced dissociation strategy.Finally, 94% phosphorylation sites within various statuses were unambiguously elucidated. | Zheyi Liu You Jiang Chunlei Xiao Xingchuang Xiong Tao Wang Jinan Li Fangjun Wang Xiang Fang Xueming Yang | 2018 | Chinese Chemical Letters2018，29，5： | 3 |
| 13 | THE FEATURE SUBSET SELECTION ALGORITHM显示文摘The motivation of data mining is how to extract effective information from huge data in very large database. However, some redundant and irrelevant attributes, which result in low performance and high computing complexity, are included in the very large database in general.So, Feature Subset Selection (FSS) becomes one important issue in the field of data mining. In this letter, an FSS model based on the filter approach is built, which uses the simulated annealing genetic algorithm. Experimental results show that convergence and stability of this algorithm are adequately achieved. | Liu Yongguo Li Xueming Wu Zhongfu (Department of Computer Science and Engineering, Chongqing University, Chongqing 400044) | 2003 | Journal of Electronics(China)2003，20，1： | 3 |
| 14 | Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors显示文摘Claudin18.2(CLDN18.2)is a tight junction protein that is overexpressed in a variety of solid tumors such as gastrointestinal cancer and oesophageal cancer.It has been identified as a promising target and a potential biomarker to diagnose tumor,evaluate efficacy,and determine patient prognosis.TST001 is a recombinant humanized CLDN18.2 antibody that selectively binds to the extracellular loop of human Claudin18.2.In this study,we constructed a solid target radionuclide zirconium-^(89)(^(89)Zr)labled-TST001 to detect the expression of in the human stomach cancer BGC823CLDN18.2 cell lines.The[^(89)Zr]Zr-desferrioxamine(DFO)-TST001 showed high radiochemical purity(RCP,>99%)and specific activity(24.15±1.34 GBq/mmol),and was stable in 5%human serum albumin,and phosphate buffer saline(>85%RCP at 96 h).The EC_(50) values of TST001 and DFO-TST001 were as high as 0.413±0.055 and 0.361±0.058 nM(P>0.05),respectively.The radiotracer had a significantly higher average standard uptake values in CLDN18.2-positive tumors than in CLDN18.2-negative tumors(1.11±0.02 vs.0.49±0.03,P=0.0016)2 days post injection(p.i.).BGC823CLDN18.2 mice models showed high tumor/muscle ratios 96 h p.i.with[^(89)Zr]Zr-DFO-TST001 was much higher than those of the other imaging groups.Immunohistochemistry results showed that BGC823CLDN18.2 tumors were highly positive(+++)for CLDN18.2,while those in the BGC823 group did not express CLDN18.2().The results of ex vivo biodistribution studies showed that there was a higher distribution in the BGC823CLDN18.2 tumor bearing mice(2.05±0.16%ID/g)than BGC823 mice(0.69±0.02%ID/g)and blocking group(0.72±0.02%ID/g).A dosimetry estimation study showed that the effective dose of[^(89)Zr]Zr-DFO-TST001 was 0.0705 mSv/MBq,which is within the range of acceptable doses for nuclear medicine research.Taken together,these results suggest that Good Manufacturing Practices produced by this immuno-positron emission tomography probe can detect CLDN18.2-overexpressing tumors. | Yan Chen Xingguo Hou Dapeng Li Jin Ding Jiayue Liu Zilei Wang Fei Teng Hongjun Li Fan Zhang Yi Gu Steven Yu Xueming Qian Zhi Yang Hua Zhu | 2023 | Journal of Pharmaceutical Analysis2023，13，4： | 2 |
| 15 | Manipulation of light in MIM plasmonic waveguide systems显示文摘Plasmonic waveguides that allow deeply subwavelength confinement of light provide an effective platform for the design of ultracompact photonic devices.As an important plasmonic waveguide,metal-insulator-metal(MIM)structure supports the propagation of light in the nanoscale regime at the visible and near-infrared ranges.Here,we focus on our work in MIM plasmonic waveguide devices for manipulating light,and review some of the recent development of this topic.We introduce MIM plasmonic wavelength filtering and demultiplexing devices,and present the electromagnetic induced transparency(EIT)-like and Fano resonance effects in MIM waveguide systems.The slow-light and rainbow trapping effects are demonstrated theoretically.These results pave a way toward dynamic control of the special and useful optical responses,which actualize some new plasmonic waveguide-integrated devices such as nanoscale filters,demultiplexers,sensors,slow light waveguides,and buffers. | LU Hua WANG GuoXi LIU XueMing | 2013 | Chinese Science Bulletin2013，58，30： | 2 |
| 16 | Boosted photoreduction of diluted CO_(2) through oxygen vacancy engineering in NiO nanoplatelets显示文摘Converting carbon dioxide(CO_(2))to diverse value-added products through photocatalysis can validly alleviate the critical issues of greenhouse effect and energy shortages simultaneously.In particular,based on practical considerations,exploring novel catalysts to achieve efficient photoreduction of diluted CO_(2) is necessary and urgent.However,this process is extremely challenging owing to the disturbance of competitive adsorption at low CO_(2) concentration.Herein,we delicately synthesize oxygen vacancy-laden NiO nanoplatelets(r-NiO)via calcination under Ar protection to reduce diluted CO_(2) through visible light irradiation(>400 nm)assisted by a Ru-based photosensitizer.Benefitting from the strongly CO_(2) adsorption energy of oxygen vacancies,which was confirmed by density functional calculations,the r-NiO catalysts exhibit higher activity and selectivity(6.28×10^(3)µmol·h^(−1)·g^(−1);82.11%)for diluted CO_(2)-to-CO conversion than that of the normal NiO(3.94×10^(3)µmol·h^(−1)·g^(−1);65.26%).Besides,the presence of oxygen vacancies can also promote the separation of electron-hole pairs.Our research demonstrates that oxygen vacancies could act as promising candidates for photocatalytic CO_(2) reduction,offering fundamental guidance for the actual photoreduction of diluted CO_(2) in the future. | Weiyi Chen Xueming Liu Bin Han Shujie Liang Hong Deng Zhang Lin | 2021 | Nano Research2021，14，3： | 2 |
| 17 | Collection System of Soil Moisture Information Based on ZigBee and GPRS显示文摘Real-time monitoring and wireless transmission of farmland soil moisture have been paid with more and more attention in the research of agricultural drought monitoring, early warning and prevention and control technology. The hardware design and software design of soil moisture monitoring in farmland were carried out, and a monitoring system based on the principles of ZigBee and GPRS technologies was developed and applied to the actual monitoring of soil moisture in farmland. This study provides a good idea to promote real-time monitoring, wireless transmission and intelligent management of soil moisture in farmland. | Haihong LIU hao JIA Yanhe LIU Qian'ao ZHAO Haoyu WANG Xueming DUAN Zhaoxin ZHANG Jianjie BI | 2019 | Agricultural Biotechnology2019，8，6： | 2 |
| 18 | Synthesis of Fe^(3+)-doped Aminated Lignin as A Peroxidase Mimic for Colorimetric Detection of H_(2)O_(2) and Glucose显示文摘Peroxidase plays an important role in living systems;however,its storage difficulty and easy inactivation have limited its applications in complex environments.To address these problems,herein,we proposed a method to synthesize peroxidase mimics by amination,carbonization,and Fe^(3+)-doping of industrial alkali lignin.The Fe^(3+)-doped lignin-based peroxidase mimic(Fe-LPM),with active centers of coordination between Fe^(3+)and N atoms,showed higher tolerance to pH value and temperature than natural peroxidase.Using Fe-LPM,10-100 mmol/L of H_(2)O_(2) and glucose could be colorimetrically detected with the lowest detection limits of 80μmol/L and 1.5 mmol/L and visual detection limits of 1.0 mmol/L and 10 mmol/L,respectively.The Fe-LPM maintained peroxidase-like activity after 10 cycles and could even be used for H_(2)O_(2) detection in practical samples.This work not only provides a new approach to synthesize peroxidase mimics using biomass materials but also promotes the high-value utilization of lignin. | Lijun Li Xin Liu Yixin Shi Jinhui Pang Jun Yang Feng Xu Xueming Zhang | 2021 | Paper And Biomaterials2021，6，4： | 2 |
| 19 | In-situ generation and global property profiling of metal nanoclusters by ultraviolet laser dissociation-mass spectrometry显示文摘Metal nanoclusters are promising nanomaterials with unique properties, but only a few ones with specific numbers of metal atoms can be obtained and studied up to now. In this study, we establish a new paradigm of in-situ generation and global study of metal nanoclusters with different sizes, constitutions, and charge states, including both accurate constitution characterization and global activity profiling. The complex mixtures of metal nanoclusters are produced by employing single-pulsed 193-nm laser dissociation of monolayer-protected cluster(MPC) precursors within a high-resolution mass spectrometry(HRMS). More than400 types of bare gold nanoclusters including novel multiply charged(2+ and 3+), S-/P-doped, and silver alloy ones can be efficiently generated and accurately characterized. A distinct size(1 to 142 atoms)-and charge(1+ to 3+)-hierarchy reactivity is clearly observed for the first time. This global cluster study might greatly promote the developments and applications of novel metal nanoclusters. | Zheyi Liu Zhaoxian Qin Chaonan Cui Zhixun Luo Bing Yang You Jiang Can Lai Zhipeng Wang Xiaolei Wang Xiang Fang Gao Li Fangjun Wang Chunlei Xiao Xueming Yang | 2022 | Science China Chemistry2022，65，6： | 2 |
| 20 | Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy显示文摘Major challenges for cancer treatment are how to effectively eliminate primary tumor and sufficiently induce immunogenic cell death(ICD)to provoke a robust immune response for metastasis control.Here,a self-assembled cascade bioreactor was developed to improve cancer treatment with enhanced tumor penetration and synergistic therapy of starvation,chemodynamic(CDT)and photothermal therapy.Ultrasmall Fe S-GOx nanodots were synthesized with glucose oxidase(GOx)as template and induced by paclitaxel(PTX)to form self-assembling Fe S-GOx@PTX(FGP)via hydrophobic interaction.After accumulated at tumor sites,FGP disassembles to smaller Fe S-GOx for enhanced deep tumor penetration.GOx maintains high enzymatic activity to catalyze glucose with assistant of oxygen to generate hydrogen peroxide(H2O2)as starvation therapy.Fenton reaction involving the regenerated H_(2)O_(2) in turn produced more hydroxyl radicals for enhanced CDT.Following near-infrared laser at 808 nm,FGPs displayed pronounced tumor inhibition in vitro and in vivo by the combination therapy.The consequent increased exposure to calreticulin amplified ICD and promoted dendritic cells maturation.In combination with anti-CTLA4 checkpoint blockade,FGP can absolutely eliminate primary tumor and avidly inhibit distant tumors due to the enhanced intratumoral infiltration of cytotoxic T lymphocytes.Our work presents a promising strategy for primary tumor and metastasis inhibition. | Hao Ren Jiahui Yong Qingqing Yang Zhen Yang Zhangya Liu Yan Xu Hao Wang Xing Jiang Wenjun Miao Xueming Li | 2021 | Acta Pharmaceutica Sinica B2021，11，10： | 2 |
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