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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019,62,2: | 11 |
| 2 | Towards a global One Health index: a potential assessment tool for One Health performance显示文摘Background:A One Health approach has been increasingly mainstreamed by the international community, as it provides for holistic thinking in recognizing the close links and inter-dependence of the health of humans, animals and the environment. However, the dearth of real-world evidence has hampered application of a One Health approach in shaping policies and practice. This study proposes the development of a potential evaluation tool for One Health performance, in order to contribute to the scientific measurement of One Health approach and the identification of gaps where One Health capacity building is most urgently needed.Methods:We describe five steps towards a global One Health index (GOHI), including (i) framework formulation;(ii) indicator selection;(iii) database building;(iv) weight determination;and (v) GOHI scores calculation. A cell-like framework for GOHI is proposed, which comprises an external drivers index (EDI), an intrinsic drivers index (IDI) and a core drivers index (CDI). We construct the indicator scheme for GOHI based on this framework after multiple rounds of panel discussions with our expert advisory committee. A fuzzy analytical hierarchy process is adopted to determine the weights for each of the indicators.Results:The weighted indicator scheme of GOHI comprises three first-level indicators, 13 second-level indicators, and 57 third-level indicators. According to the pilot analysis based on the data from more than 200 countries/territories the GOHI scores overall are far from ideal (the highest score of 65.0 out of a maximum score of 100), and we found considerable variations among different countries/territories (31.8–65.0). The results from the pilot analysis are consistent with the results from a literature review, which suggests that a GOHI as a potential tool for the assessment of One Health performance might be feasible.Conclusions:GOHI—subject to rigorous validation—would represent the world’s first evaluation tool that constructs the conceptual framework from a holistic perspective of One Health. Future application of GOHI might promote a common understanding of a strong One Health approach and provide reference for promoting effective measures to strengthen One Health capacity building. With further adaptations under various scenarios, GOHI, along with its technical protocols and databases, will be updated regularly to address current technical limitations, and capture new knowledge. | Xiao-Xi Zhang Jing-Shu Liu Le-Fei Han Shang Xia Shi-Zhu Li Odel YLi Kokouvi Kassegne Min Li Kun Yin Qin-Qin Hu Le-Shan Xiu Yong-Zhang Zhu Liang-Yu Huang Xiang-Cheng Wang Yi Zhang Han-Qing Zhao Jing-Xian Yin Tian-Ge Jiang Qin Li Si-Wei Fei Si-Yu Gu Fu-Min Chen Nan Zhou Zi-Le Cheng Yi Xie Hui-Min Li Jin Chen Zhao-Yu Guo Jia-Xin Feng Lin Ai Jing-Bo Xue Qian Ye Liz Grant Jun-Xia Song Geoff Simm Jürg Utzinger Xiao-Kui Guo Xiao-Nong Zhou | 2022 | Infectious Diseases of Poverty2022,11,3: | 3 |
| 3 | Non-invasive intrana- sal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cere- bral artery occlusion显示文摘 | Liu XF Fawcett JR Thorne RG | 2001 | Neurosci Lett2001,308,2: | 1 |
| 4 | The role of capain in oneotic cell death显示文摘 | Liu X Van Vleet T Schnellmann RG | 2004 | Annu Rew Pharmacol Toxicol2004,44,: | 1 |
| 5 | Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage显示文摘 | Liu XF Fawcett JR Thorne RG | 2001 | J Neurol Sci2001,187,: | 1 |
| 6 | The effect of repeated stretching on the force decay and compliance of vu- lcanized cis-polyisoprene orthodontic elastics显示文摘 | Liu CC Wataha JC Craig RG | 1993 | Dent Mater1993,9,1: | 1 |
| 7 | Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage显示文摘 | Liu XF Fawcett JR Thorne RG | 2001 | J Neurol Sci2001,187,12: | 1 |
| 8 | Prcine coronary artery organ culture: a model for the study of angioplasty injury显示文摘 | Carere RG Koo EWY Liu PP | 1992 | Cardiovascular Pathol1992,1,2: | 1 |
| 9 | Noninvasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic functions following middle cerebral artery occlusion in rats显示文摘 | Liu XF Fawcett JR Throne RG | 2001 | Neurosci Lett2001,308,: | 1 |
| 10 | Augmentation of nitric oxide,superoxide and peroxynitrite production during cerebral ischemia and reperfusion in the rat显示文摘 | FormanL Liu J P Nagele RG | 1998 | Neurochem Res1998,23,: | 1 |
| 11 | Intranasal administration of insulinlike growth factor-1 bypasses the blood-brain barrier and protects against focal cerebral ischemic damage显示文摘 | Fawcett JR Throne RG | 2001 | J Neurol Sci2001,187,: | 1 |
| 12 | Radical polymerization of N-显示文摘 | JY Ai PS Liu HY Tan RG Lei | 2001 | J App PolymSci2001,8,2: | 1 |
| 13 | Multiplefunctions of caveolin-1显示文摘 | Liu P Rudick M Anderson RG | 2002 | J Biol Chem2002,277,41: | 1 |
| 14 | Paper spray for direct analysis of complex mixtures using mass spectrometry显示文摘 | Wang H Liu JJ Cooks RG | | Angewandte Chemie International Edition0,,: | 1 |
| 15 | Ischemic injury and faulty gene trnscripts in the brain 显示文摘 | Liu PK Grossman RG Hsu CY | 2001 | Trends Neurosci2001,24,10: | 1 |
| 16 | Multiple functions of caveolin-1 显示文摘 | Liu P Rudick M Anderson RG | 2002 | J Biol Chem2002,277,41: | 1 |
| 17 | Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults显示文摘 | Binder EB Bradley RG Liu W | 2008 | JAMA2008,299,11: | 1 |
| 18 | Indoor air pollution and risk of lung cancer among Chinese female non-smokers 显示文摘 | Mu LN Liu L Niu RG | 2013 | Cancer Causes Control2013,24,3: | 1 |
| 19 | Characterization of plasmodium yoelii antigens by monoclonal antibodies, I , Common antigens between erythrocytic stages 9f plasmodium yoelii and human malaria parasites 显示文摘 | Li WL Liu EX Fan RG | 1984 | Ji Sheng Chong Xue /de Ji Sheng Chong Bing Za Zhi1984,2,2: | 1 |
| 20 | Lysophosphatidic acid stimulates proliferation of human retinal pigment epithelial cells显示文摘 | Thoreson WB Khandalavala BN Manahan RG Polyak IA Liu JL Chacko DM | 1997 | Curr Eye Res1997,16,: | 1 |