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| 1 | Modified constraint-induced movement therapy alters synaptic plasticity of rat contralateral hippocampus following middle cerebral artery occlusion显示文摘Modified constraint-induced movement therapy is an effective treatment for neurological and motor impairments in patients with stroke by increasing the use of their affected limb and limiting the contralateral limb.However,the molecular mechanism underlying its efficacy remains unclear.In this study,a middle cerebral artery occlusion(MCAO)rat model was produced by the suture method.Rats received modified constraint-induced movement therapy 1 hour a day for 14 consecutive days,starting from the 7^th day after middle cerebral artery occlusion.Day 1 of treatment lasted for 10 minutes at 2r/min,day 2 for 20 minutes at 2 r/min,and from day 3 onward for 20 minutes at 4 r/min.CatWalk gait analysis,adhesive removal test,and Y-maze test were used to investigate motor function,sensory function as well as cognitive function in rodent animals from the 1st day before MCAO to the 21^st day after MCAO.On the 21^st day after MCAO,the neurotransmitter receptor-related genes from both contralateral and ipsilateral hippocampi were tested by micro-array and then verified by western blot assay.The glutamate related receptor was shown by transmission electron microscopy and the glutamate content was determined by high-performance liquid chromatography.The results of behavior tests showed that modified constraint-induced movement therapy promoted motor and sensory functional recovery in the middle cerebral artery-occluded rats,but had no effect on cognitive function.The modified constraint-induced movement therapy upregulated the expression of glutamate ionotropic receptor AMPA type subunit 3(Gria3)in the hippocampus and downregulated the expression of the beta3-adrenergic receptor gene Adrb3 and arginine vasopressin receptor 1 A,Avprla in the middle cerebral artery-occluded rats.In the ipsilateral hippocampus,only Adra2 a was downregulated,and there was no significant change in Gria3.Transmission electron microscopy revealed a denser distribution the more distribution of postsynaptic glutamate receptor 2/3,which is an a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor,within 240 nm of the postsynaptic density in the contralateral cornu ammonis 3 region.The size and distribution of the synaptic vesicles within 100 nm of the presynaptic active zone were unchanged.Western blot analysis showed that modified constraint-induced movement therapy also increased the expression of glutamate receptor 2/3 and brain-derived neurotrophic factor in the hippocampus of rats with middle cerebral artery occlusion,but had no effect on Synapsin I levels.Besides,we also found modified constraint-induced movement therapy effectively reduced glutamate content in the contralateral hippocampus.This study demonstrated that modified constraint-induced movement therapy is an effective rehabilitation therapy in middle cerebral artery-occluded rats,and suggests that these positive effects occur via the upregulation of the postsynaptic membrane a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor expression.This study was approved by the Institutional Animal Care and Use Committee of Fudan University,China(approval No.201802173 S)on March 3,2018. | Bei-Yao Gao Dong-Sheng Xu Pei-Le Liu Ce Li Liang Du Yan Hua Jian Hu Jia-Yun Hou Yu-Long Bai | 2020 | Neural Regeneration Research2020，15，6： | 19 |
| 2 | Three-year results of small incision lenticule extraction and wavefront-guided femtosecond laser-assisted laser in situ keratomileusis for correction of high myopia and myopic astigmatism显示文摘AIM: To compare and calculate the 3-year refractive results, higher-order aberrations(HOAs), contrast sensitivity(CS) and dry eye parameters after small incision lenticule extraction(SMILE) and wavefront-guided femtosecond laser-assisted laser in situ keratomileusis(FS-LASIK) for correction of high myopia and myopic astigmatism.METHODS: In this prospective, non-randomized comparative study, 78 eyes with spherical equivalent(SE) of-8.11±1.09 diopters(D) received a SMILE surgery, and 65 eyes with SE of-8.05±1.12 D received a wavefront-guided FS-LASIK surgery with the Visu Max femtosecond laser(Carl Zeiss Meditec, Jena, Germany) for flap cutting. Visual acuity, manifest refraction, CS, HOAs, ocular surface disease index(OSDI) and tear break-up time(TBUT) were evaluated during a 3-year follow-up.RESULTS: The difference of uncorrected distance visual acuity(UDVA) postoperatively was achieved at 1 mo and at3 mo, whereas the difference of the mean UDVA between two groups at 3 y were not statistically significant(t=-1.59,P=0.13). The postoperative change of SE was 0.89 D in the FS-LASIK group(t=5.76, P=0.00), and 0.14 D in the SMILE group(t=0.54, P=0.59) from 1 mo to 3 y after surgery.At 3-year postoperatively, both HOAs and spherical aberrations in the SMILE group were obviously less than those in the FS-LASIK group(P=0.00), but the coma root mean square(RMS) was higher in the SMILE group(0.59±0.26) than in the FS-LASIK group(0.29±0.14, P=0.00).The mesopic CS values between two groups were not statistically significant at 3 y postoperatively. Comparedwith the FS-LASIK group, lower OSDI scores and longer TBUT values were found in the SMILE group at 1 mo and 3 mo postoperatively. With regard to safety, no eye lost any line of CDVA in both groups at 3 y after surgery. CONCLUSION: Both SMILE and wavefront-guided FSLASIK procedures provide good visual outcomes. Both procedures are effective and safe, but SMILE surgery achieve more stable long-term refractive outcome and better control of early postoperative dry eye as compared to FS-LASIK. | Li-Kun Xia Jing Ma He-Nan Liu Ce Shi Qing Huang | 2018 | International Journal of Ophthalmology(English edition)2018，11，3： | 16 |
| 3 | Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes显示文摘During the pathogensis of rheumatoid arthritis(RA),activated RA fibroblast-like synoviocytes(RA-FLSs)combines similar proliferative features as tumor and inflammatory features as osteoarthritis,which eventually leads to joint erosion.Therefore,it is imperative to research and develop new compounds,which can effectively inhibit abnormal activation of RA-FLSs and retard RA progression.Neohesperidin(Neo)is a major active component of flavonoid compounds with anti-inflammation and anti-oxidant properties.In this study,the anti-inflammation,anti-migration,anti-invasion,anti-oxidant and apoptosis-induced effects of Neo on RAFLSs were explored to investigate the underlying mechanism.The results suggested that Neo decreased the levels of interleukin IL-1β,IL-6,IL-8,TNF-α,MMP-3,MMP-9 and MMP-13 in FLSs.Moreover,Neo blocked the activation of the MAPK signaling pathway.Furthermore,treatment with Neo induced the apoptosis of FLSs,and inhibited the migration of FLSs.It was also found that Neo reduced the accumulation of reactive oxygen species(ROS)induced by TNF-α.Taken together,our results highlighted that Neo may act as a potential and promising therapeutic drug for the management of RA. | WANG Xiao-He DAI Ce WANG Jun LIU Rui LI Lei YIN Zong-Sheng | 2021 | Chinese Journal of Natural Medicines2021，19，10： | 10 |
| 4 | Potential of multi-pass ECAP on improving the mechanical properties of a high-calcium-content Mg-Al-Ca-Mn alloy显示文摘In this study,the multi-pass equal channel angular pressing(ECAP)was employed on a high-calcium-content Mg-Al-Ca-Mn alloy to tailor its microstructure and mechanical properties.The obtained results showed that the network-shaped Mg2Ca and(Mg,Al)2Ca eutectic compounds in as-cast alloy were gradually crushed into ultra-fine particles after ECAP,which exhibited a bimodal particle size distribution and most aggregated at original grain boundaries.Dynamic recrystallization(DRX)of α-Mg occurred during hot deformation via a particle stimulated mechanism,and the almost complete DRX with an average grain size around 1.5μm was obtained after 12p-ECAP.Moreover,abundant nano-sized acicular and spherical precipitates were dynamically precipitated withinα-Mg grains during ECAP.Tensile test results indicated that the maximum strength and ductility were acquired for 12p-ECAP alloy with ultimate tensile strength of 372 MPa and fracture elongation of 8%.The enhanced strength of the alloy could be ascribed to fine DRX grains,ultra-fine Ca-containing particles and dynamically precipitated nano-precipitates,while the improved ductility was mainly due to the refined and homogeneous microstructure,and weak texture with high average Schmid factors. | He Huang Huan Liu Ce Wang Jiapeng Sun Jing Bai Feng Xue Jinghua Jiang Aibin Ma | 2019 | Journal of Magnesium and Alloys2019，7，4： | 10 |
| 5 | Non-axisymmetric Flow Characteristics in Centrifugal Compressor显示文摘The flow field distribution in centrifugal compressor is significantly affected by the non-axisymmetric geometry structure of the volute.The experimental and numerical simulation methods were adopted in this work to study the compressor flow field distribution with different flow conditions.The results show that the pressure distribution in volute is characterized by the circumferential non-uniform phenomenon and the pressure fluctuation on the high static pressure zone propagates reversely to upstream,which results in the non-axisymmetric flow inside the compressor.The non-uniform level of pressure distribution in large flow condition is higher than that in small flow condition,its effect on the upstream flow field is also stronger.Additionally,the non-uniform circumferential pressure distribution in volute brings the non-axisymmetric flow at impeller outlet.In different flow conditions,the circumferential variation of the absolute flow angle at impeller outlet is also different.Meanwhile,the non-axisymmetric flow characteristics in internal impeller can be also reflected by the distribution of the mass flow.The high static pressure region of the volute corresponds to the decrease of mass flow in upstream blade channel,while the low static pressure zone of the volute corresponds to the increase of the mass flow.In small flow condition,the mass flow difference in the blade channel is bigger than that in the large flow condition. | WANG Leilei LAO Dazhong LIU Yixiong YANG Ce | 2015 | Journal of Thermal Science2015，24，4： | 7 |
| 6 | Improving toughness of a Mg_(2)Ca-containing Mg-Al-Ca-Mn alloy via refinement and uniform dispersion of Mg_(2)Ca particles显示文摘In this work,two wrought Mg-3.66Al-4.25Ca-0.43 Mn(wt%)alloys with different morphology and distribution of Mg_(2)Ca particles were fabricated by hot extrusion and multi-pass(32)equal channel angular pressing(ECAP).The as-extruded alloy exhibits a banded microstructure with alternately arranged Mg_(2)Ca particle bands,fine α-Mg dynamically recrystallized(DRX)grain bands,and coarse α-Mg deformed grain bands.The Mg_(2)Ca bands are composed of broken Mg_(2)Ca particles which are aggregated and aligned along extrusion direction.The microstructure of ECAP alloy contains complete α-Mg DRX grains and refined Mg_(2)Ca particles which are dispersedly distributed at grain boundaries.Tensile test results show that the as-extruded alloy possesses high ultimate tensile strength(UTS)of 420 MPa and poor fracture elongation of 7%,while the ECAP alloy exhibits improved toughness with UTS of 347 MPa and fraction elongation of 16%.The higher strength of as-extruded alloy is mainly ascribed to the contribution of coarse deformed grains with strong texture,and its poor toughness is resulted from the formation of Mg_(2)Ca bands within which microcracks could form and extend rapidly.On the contrary,the refined and dispersedly distributed Mg_(2)Ca particles are effective to retard crack initiation and impede crack propagation,thereby enhancing the toughness of ECAP alloy significantly. | Huan Liu Chao Sun Ce Wang Yuhua Li Jing Bai Feng Xue Aibin Ma Jinghua Jiang | 2020 | Journal of Materials Science & Technology2020，59，24： | 7 |
| 7 | Fe5C2 nanoparticles as low-cost HER electrocatalyst:the importance of Co substitution显示文摘Constructing and understanding the doping effect of secondary metal in transition metal carbide(TMC)catalysts is pivotal for the design of low-cost hydrogen evolution reaction(HER) electrocatalysts. In this work, we developed a wet-chemistry strategy for synthesizing Co-modified Fe_5C_2 nanoparticles((Fe_(1-x)Cox)_5C_2 NPs) as highly active HER electrocatalysts in basic solution. The structure of(Fe_(1-x)Cox)_5C_2 NPs was characterized by X-ray diffraction(XRD), extended X-ray absorption fine structure spectra(EXAFS) and scanning/transmission electron microscopy(S/TEM), indicating that the isomorphous substitution of cobalt in the lattice of Fe_5C_2.(Fe_(0.75) Co_(0.25))_5C_2 exhibited the best HER activity(174 mV for j = -10 mA/cm^2). Computational calculation results indicate that Co provides the most active site for HER. X-ray adsorption spectra(XAS) studies further suggested that the electron transfer in Fe–C bonds are enhanced by the substitution of Co, which modulates the hydrogen adsorption on the adjacent electronic-enriched carbon, and therefore promotes HER activity. Our results affirm the design of lowcost bimetallic TMCs based HER catalysts. | Siwei Li Pengju Ren Ce Yang Xi Liu Zhen Yin Weizhen Li Hanjun Yang Jian Li Xiaoping Wang Yi Wang Ruochen Cao Lili Lin Siyu Yao Xiaodong Wen Ding Ma | 2018 | Science Bulletin2018，63，20： | 6 |
| 8 | An Airfoil Parameterization Method for the Representation and Optimization of Wind Turbine Special Airfoil显示文摘A new airfoil shape parameterization method is developed, which extended the Bezier curve to the generalized form with adjustable shape parameters. The local control parameters at airfoil leading and trailing edge regions are enhanced, where have significant effect on the aerodynamic performance of wind turbine. The results show this improved parameterization method has advantages in the fitting characteristics of geometry shape and aerodynamic performance comparing with other three common airfoil parameterization methods. The new parameterization method is then applied to airfoil shape optimization for wind turbine using Genetic Algorithm(GA), and the wind turbine special airfoil, DU93-W-210, is optimized to achieve the favorable Cl/Cd at specified flow conditions. The aerodynamic characteristic of the optimum airfoil is obtained by solving the RANS equations in computational fluid dynamics(CFD) method, and the optimization convergence curves show that the new parameterization method has good convergence rate in less number of generations comparing with other methods. It is concluded that the new method not only has well controllability and completeness in airfoil shape representation and provides more flexibility in expressing the airfoil geometry shape, but also is capable to find efficient and optimal wind turbine airfoil. Additionally, it is shown that a suitable parameterization method is helpful for improving the convergence rate of the optimization algorithm. | LIU Yixiong YANG Ce SONG Xiancheng | 2015 | Journal of Thermal Science2015，24，2： | 6 |
| 9 | Microstructure and Mechanical Properties of Mg–RE–TM Cast Alloys Containing Long Period Stacking Ordered Phases: A Review显示文摘Casting magnesium alloys hold the greatest share of magnesium application products due to their short processing period, low cost and near net shape forming. Compared with conventional commercial magnesium alloys or other Mg–RE-based alloys, the novel Mg–RE–TM cast alloys with long period stacking ordered(LPSO) phases usually possess a higher strength and are promising candidates for aluminum alloy applications. Up to now, two ways: alloying design and casting process control(including subsequent heat treatments), have been predominantly employed to further improve the mechanical properties of these alloys. Alloying with other elements or ceramic particles could alter the solidifi cation pattern of alloys, change the morphology of LPSO phases and refi ne the microstructures. Diff erent casting techniques(conventional casting, rapidly solidifi cation, directional solidifi cation, etc.) introduce various microstructure characteristics, such as dendritic structure, nanocrystalline, metastable phase, anisotropy. Further heat treatments could activate the transformation of various LPSO structures and precipitation of diverse precipitates. All these evolutions exert great impacts on the mechanical properties of the LPSO-containing alloys. However, the underlying mechanisms still remain a subject of debate. Therefore, this review mainly provides the state of the art of the casting magnesium alloys research and the accompanying challenges and summarizes some topics that merit future investigation for developing high-performance Mg–RE–TM cast alloys. | Huan Liu He Huang Jia-Peng Sun Ce Wang Jing Bai Ai-Bin Ma Xian-Hua Chen | 2019 | Acta Metallurgica Sinica(English Letters)2019，32，3： | 6 |
| 10 | Structure,rheology and electrospinning of zein and poly(ethylene oxide) in aqueous ethanol solutions显示文摘Electrospun fiber mats (EFM) integrated proteins and biocompatible polymers have been widely used as tissue scaffold, wound dressing and food packaging. The morphology of EFM has strong correlation with the structure and rheology of the solutions. We studied the structure and rheology of polyethylene oxide (PEO) and zein in 80% ethanol aqueous solutions and the resulted EFM. In solutions, zein with rod-like conformation tends to aggregate and form oligomer, the number of proteins in the oligomer spans from 2.5 to 55.2, while PEO always behaves like Gaussian chain in good solvent. Zein preferred to distribute along PEO chains in their mixed solutions, and the structures decomposed from small angle X-ray scattering have consistent relaxation spatial-temporal characteristics with rheological behaviors.Further, the aging of zein solutions enhanced shear thinning and resulted thicker fibers in EFM, which are attributed to the rod-like growth of zein aggregates. Aggregates in viscous media with long enough relaxation time are probably crucial for the formation of continuous electrospun fibers or ribbons. This study provides a clear correlation of the structure, rheology of solutions with the morphologies of EFM made up of proteins and polymers. | Ce Shi Shixia Xi Yingchun Han Hao Zhang Jingsheng Liu Yunqi Li | 2019 | Chinese Chemical Letters2019，30，2： | 5 |
| 11 | Precise temporal regulation of Dux is important for embryo development显示文摘Dear Editor,Zygotic genome activation(ZGA)following fertilization is accomplished through a process termed the maternal-to-zygotic transition,during which the maternal RNAs and proteins are degraded and zygotic genome is transcriptionally activated.In mice,minor ZGA occurs from S phase of the zygote to G1 phase of the two-cell(2C)embryo,while major ZGA takes place during the middle-to-late 2C stage with a burst of transcription of totipotent cleavage stage-specific genes and retrotransposons. | Mingyue Guo Yanping Zhang Jianfeng Zhou Yan Bi Junqin Xu Ce Xu Xiaochen Kou Yanhong Zhao Yanhe Li Zhifen Tu Kuisheng Liu Jiaming Lin Peng Yang Shaorong Gao Yixuan Wang | 2019 | Cell Research2019，29，11： | 5 |
| 12 | Comparison of intravitreal injection of conbercept and triamcinolone acetonide for macular edema secondary to branch retinal vein occlusion显示文摘AIM:To compare the safety and efficacy of the intravitreal injection of conbercept(IVC)and triamcinolone acetonide(IVTA)for macular edema(ME)secondary to branch retinal vein occlusion(BRVO).METHODS:A prospective,randomized clinical study.Patients with ME secondary to BRVO were randomly assigned to either IVC group or IVTA group at a ratio of 2:1 and a 12-month follow-up was performed.The efficacy outcome measures included the mean changes and differences in best corrected visual acuity(BCVA)and the central retinal thickness(CRT).The safety profiles and the mean retreatment intervals were also compared.RESULTS:There was no statistically significant difference of baseline between the two groups(IVC group,n=36;IVTA group,n=17).At 12mof the BCVA letters improved by 27.31±18.36 in the IVC group,and 13.53±11.37 in the IVTA group(P=0.0004).CRT reduction was 253.33±163.69 and 150.24±134.32 pm,respectively(P=0.0034).The mean BCVA in the IVC group was superior to that of the IVTA group for months 6-12(P<0.01).The mean CRT at 9 and 12mo were thinner in the IVC group compared to the IVTA group(P<0.01).The mean retreatment interval in the IVC group was longer than that in the IVTA group(97.40±36.27d vs 68.71±36.38d,P=0.0030).One eye in the IVC group and seven eyes in the IVTA group developed elevated intraocular pressure(IOP;P=0.0012).The proportion of eyes with cataract new-onset or progression were 19.44%in the IVC group and 64.71%in the IVTA group(P=0.0012).CONCLUSION:IVC could maintain or improve BCVA and reduce CRT for a longer time and have longer retreatment interval than IVTA.In addition,patients treated with IVTA are more susceptible to IOP elevation and cataract progression. | Miao Zhao Ce Zhang Xi-Mei Chen Yan Teng Tian-Wei Shi Fei Liu | 2020 | International Journal of Ophthalmology(English edition)2020，13，11： | 4 |
| 13 | Size,morphology,and composition of lunar samples returned by Chang'E-5 mission显示文摘This study focuses on the physical and chemical properties of surficial lunar regolith(LR)samples returned from the Moon by the Chang’E-5(CE-5)mission.Insights regarding the effect of a new sampling geological site on the surficial lunar sample CE5 C0400 were illustrated using nondestructive techniques such as laser diffractometry coupled with image analysis,X-ray computed tomography,and field emission scanning electron microscopy equipped with energy dispersive spectroscopy,and Xray diffraction combined with Rietveld refinement.From the characterization analyses,the CE-5 sampling site in the northeastern Oceanus Procellarum on the Moon yields a unique collection of relatively regular-shaped and fine basalt-dominated particles.The median grain size D_(50) is(55.24±0.96)μm,falling within the relatively low end of the range of the Apollo lunar returned samples.The coefficient of uniformity C_(u)of 15.1 and the coefficient of curvature C_(c)of 1.7 could classify CE5 C0400 to be well-graded.The minerals in CE5 C0400 comprise approximately 44.5%pyroxene,30.4%plagioclase,3.6%olivine,and6.0%ilmenite.There is a relatively low content of approximately 15.5%glass phase in the CE-5 lunar sample.From the results,we deduce that the CE-5 LR structure could have mainly resulted from micrometeoroid impacts to achieve such a high level of maturity. | Hui Zhang Xian Zhang Guang Zhang Keqi Dong Xiangjin Deng Xiaosong Gao Yaodong Yang Yuan Xiao Xiao Bai Kaixin Liang Yiwei Liu Wenbin Ma Shaofan Zhao Ce Zhang Xiaojing Zhang Jian Song Wei Yao Hong Chen Weihua Wang Zhigang Zou Mengfei Yang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，2： | 4 |
| 14 | Effects of Normalized Difference Vegetation Index and Related Wavebands′ Characteristics on Detecting Spatial Heterogeneity Using Variogram-based Analysis显示文摘Spatial heterogeneity is widely used in diverse applications, such as recognizing ecological process, guiding ecological restoration, managing land use, etc. Many researches have focused on the inherent scale multiplicity of spatial heterogeneity by using various environmental variables. How these variables affect their corresponding spatial heterogeneities, however, have received little attention. In this paper, we examined the effects of characteristics of normalized difference vegetation index (NDVI) and its related bands variable images, namely red and near infrared (NIR), on their corresponding spatial heterogeneity detection based on variogram models. In a coastal wetland region, two groups of study sites with distinct fractal vegetation cover were tested and analyzed. The results show that: 1) in high fractal vegetation cover (H-FVC) area, NDVI and NIR variables display a similar ability in detecting the spatial heterogeneity caused by vegetation growing status structure; 2) in low fractal vegetation cover (L-FVC) area, the NIR and red variables outperform NDVI in the survey of soil spatial heterogeneity; and 3) generally, NIR variable is ubiquitously applicable for vegetation spatial heterogeneity investigation in different fractal vegetation covers. Moreover, as variable selection for remote sensing applications should fully take the characteristics of variables and the study object into account, the proposed variogram analysis method can make the variable selection objectively and scientifically, especially in studies related to spatial heterogeneity using remotely sensed data. | WEN Zhaofei ZHANG Ce ZHANG Shuqing DING Changhong LIU Chunyue PAN Xin LI Huapeng SUN Yan | 2012 | Chinese Geographical Science2012，22，2： | 4 |
| 15 | Effect of lactic acid bacteria inoculants on alfalfa(Medicago sativa L.) silage quality:assessment of degradation(in situ) and gas production(in vitro)显示文摘Alfalfa(Medicago sativa) is difficult to ensile successfully because of the low content of moisture and water-soluble carbohydrates(WSC) in fresh alfalfa and the high buffering capacity in fresh alfalfa. Here, we conducted a study to evaluate the effects of three lactic acid bacteria(LAB) inoculants(Lactobacillus casei, Lactobacillus plantarum, and Pediococcus pentosaceus) on silage quality, in situ ruminal degradability, and in vitro fermentation of alfalfa silage. The first cut of alfalfa was wilted, chopped, and randomly divided into four groups: the control(CON) and control mixed with three separate LAB inoculants(10~6 cfug^(–1)). Simmental steers with a body weight of(452±18) kg and with installed rumen fistulas were prepared for in situ degradation and for in vitro gas production. LAB inoculants had a lower(P<0.05) content of butyric acid than the CON group. Among them, the L. casei inoculated silage had a higher(P<0.05) content of water-soluble carbohydrate(WSC) and a lower(P<0.05) NH_3-H content. The effective degradation(ED) of crude protein in LAB inoculation decreased(P<0.05), while the ED of acid detergent fiber increased(P<0.05) in situ fermentation. The alfalfa silage with LAB inoculants produced more carbon dioxide(P<0.05). The NH_3-H content of mixed incubation fluid in L. casei inoculated silage was lower(P<0.05) compared with other groups. Therefore, this study showed that LAB inoculants could improve both ensiling quality and degradation. In particular, the L. casei inoculations exhibited better performance by limiting proteolysis during ensiling. | LIU Ce LAI Yu-jiao LU Xiao-nan GUO Ping-ting LUO Hai-ling | 2016 | Journal of Integrative Agriculture2016，15，12： | 3 |
| 16 | Properties,combustion behavior,and kinetic triplets of coke produced by low-temperature oxidation and pyrolysis:Implications for heavy oil in-situ combustion显示文摘This work aimed at investigating the crucial factor in building and maintaining the combustion front during in-situ combustion(ISC),oxidized coke and pyrolyzed coke.The surface morphologies,elemental contents,and non-isothermal mass losses of the oxidized and pyrolyzed cokes were thoroughly examined.The results indicated that the oxidized coke could be combusted at a lower temperature compared to the pyrolyzed coke due primarily to their differences in the molecular polarity and microstructure.Kinetic triplets of coke combustion were determined using iso-conversional models and one advanced integral master plots method.The activation energy values of the oxidized and pyrolyzed cokes varied in the range of 130-153 k J/mol and 95-120 kJ/mol,respectively.The most appropriate reaction model of combustion of the oxidized and pyrolyzed cokes followed three-dimensional diffusion model(D_(3)) and random nucleation and subsequent growth model(F_(1)),respectively.These observations assisted in building the numerical model of these two types of cokes to simulate the ISC process. | Shuai Zhao Wan-Fen Pu Lei Su Ce Shang Yang Song Wei Li Hui-Zhuo He Yi-Gang Liu Zhe-Zhi Liu | 2021 | Petroleum Science2021，18，5： | 3 |
| 17 | Numerical study on dynamic mechanism of brain volume and shear deformation under blast loading显示文摘Blast-induced traumatic brain injury(b-TBI)is a kind of significant injury to soldiers in the current military conflicts.However,the mechanism of b-TBI has not been well understood,and even there are some contradictory conclusions.It is crucial to reveal the dynamic mechanism of brain volume and shear deformations under blast loading for better understanding of b-TBI.In this paper,the numerical simulation method is adopted to carry out comprehensive and in-depth researches on this issue for the first time.Based on the coupled Eulerian-Lagrangian method,the fluid-structure coupling model of the blast wave and human head is developed to simulate two situations,namely the head subjected to the frontal and lateral impacts.The simulation results are analyzed to obtain the underlying dynamic mechanisms of brain deformation.The brain volume deformation is dominated by the local bending vibration of the skull,and the corresponding frequency for the forehead skull under the frontal impact and the lateral skull faced to the lateral impact is as high as 8 kHz and 5 kHz,respectively.This leads to the high-frequency fluctuation of brain pressure and the large pressure gradient along the skull,totally different from the dynamic response of brain under head collisions.While the brain shear deformation mainly depends on the relative tangential displacement between the skull and brain and the anatomical structure of inner skull,being not related to the brain pressure and its gradient.By further comparing the medical statistics,it is inferred that diffuse axonal injury and brain contusion,the two most common types of b-TBI,are mainly attributed to brain shear deformations.And the von Mises stress can be adopted as the indicator for these two brain injuries.This study can provide theoretical guidance for the diagnosis of b-TBI and the development of protective equipment. | Zhijie Li Zhibo Du Xiaochuan You Zhanli Liu Jian Cheng Chengcheng Luo Dongyang Chu Shaowu Ning Yue Kang Ce Yang Zhuo Zhuang | 2019 | Acta Mechanica Sinica2019，35，5： | 3 |
| 18 | 一种基于感应原理的城市地下管道检查孔定位系统显示文摘介绍一种用于城市各种地下管道中被覆盖的检查孔定位的检测系统。系统的传感器由探头及发射和接收电路组成。根据电磁感应原理设计了实用的探头线圈。发射电路产生发射线圈所需的激励,接收电路处理来自接收线圈的检测信号。由地面上的数据采集系统根据检测信号以及距离检测结果得到被覆盖检查孔的准确定位信息。经过实际管道中的现场实验,得到了令人满意的测试结果。 | 穆向阳 汤楠 江秀汉 Richard Ce Liu | 2004 | 电子技术应用2004，30，6： | 3 |
| 19 | Forced Responses on a Radial Turbine with Nozzle Guide Vanes显示文摘Radial turbines with nozzle guide vanes are widely used in various size turbochargers.However,due to the interferences with guide vanes,the blades of impellers are exposed to intense unsteady aerodynamic excitations,which cause blade vibrations and lead to high cycle failures(HCF).Moreover,the harmonic resonance in some frequency regions are unavoidable due to the wide operation conditions.Aiming to achieve a detail insight into vibration characteristics of radial flow turbine,a numerical method based on fluid structure interaction(FSI) is presented.Firstly,the unsteady aerodynamic loads are determined by computational fluid dynamics(CFD).And the fluctuating pressures are transformed from time domain to frequency domain by fast Fourier-transform(FFT).Then,the entire rotor model is adopted to analyze frequencies and mode shapes considering mistuning in finite element(FE) method.Meanwhile,harmonic analyses,applying the pressure fluctuation from CFD,are conducted to investigate the impeller vibration behavior and blade forced response in frequency domain.The prediction of the vibration dynamic stress shows acceptable agreement to the blade actual damage in consistent tendency. | LIU Yixiong YANG Ce MA Chaochen LAO DaZhong | 2014 | Journal of Thermal Science2014，23，2： | 3 |
| 20 | Drimane Sesquiterpenoids and Isochromone Derivative from the Endophytic Fungus Pestalotiopsis sp. M-23显示文摘Three new drimane sesquiterpenoids(1–3)together with the known 2a-hydroxyisodrimeninol(4),and a new isochromone derivative(5),were obtained from the solid cultures of fungal strain Pestalotiopsis sp.M-23,an endophytic fungus isolated from the leaves of Leucosceptrum canum(Labiatae).Their structures were determined by comprehensive 1D and 2D NMR,and MS analyses.The metabolites were evaluated for their antibacterial activities,and compound 3 showed weak inhibitory activity against Bacillus subtilis. | Ce Kuang Shu-Xi Jing Yan Liu Shi-Hong Luo Sheng-Hong Li | 2016 | Natural Products and Bioprospecting2016，6，3： | 3 |
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