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| 1 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 2 | Mycorrhizal fungal community composition in seven orchid species inhabiting Song Mountain, Beijing, China显示文摘Mycorrhizal fungi play an important role in the germination and growth of orchids essentially influencing their survival,abundance, and spatial distribution. In this study, we investigated the composition of the mycorrhizal fungal community in seven terrestrial orchid species inhabiting Song Mountain, Beijing, China, using Illumina MiSeq high-throughput sequencing. The mycorrhizal communities in the seven orchids were mainly composed of members of the Ceratobasidiaceae, Sebacinales, and Tulasnellaceae, while a number of ectomycorrhizal fungi belonging to the Russulaceae, Tricholomataceae, Thelephoraceae, and Cortinariaceae were occasionally observed. However, the dominant fungal associates and mycorrhizal community differed significantly among the orchid species as well as subhabitats. These findings confirm the previous observation that sympatric orchid species show different preferences for mycorrhizal fungi, which may drive niche partitioning and contribute to their cooccurrence. | Yanhong Chen Yue Gao Linli Song Zeyu Zhao Shunxing Guo Xiaoke Xing | 2019 | Science China(Life Sciences)2019，62，6： | 6 |
| 3 | Non-genetic photoacoustic stimulation of single neurons by a tapered fiber optoacoustic emitter显示文摘Neuromodulation at high spatial resolution poses great significance in advancing fundamental knowledge in the field of neuroscience and offering novel clinical treatments.Here,we developed a tapered fiber optoacoustic emitter(TFOE)generating an ultrasound field with a high spatial precision of 39.6 pm,enabling optoacoustic activation of single neurons or subcellular structures,such as axons and dendrites.Temporally,a single acoustic pulse of sub-microsecond converted by the TFOE from a single laser pulse of 3 ns is shown as the shortest acoustic stimuli so far for successful neuron activation.The precise ultrasound generated by the TFOE enabled the integration of the optoacoustic stimulation with highly stable patch-clamp recording on single neurons.Direct measurements of the electrical response of single neurons to acoustic stimulation,which is difficult for conventional ultrasound stimulation,have been demonstrated.By coupling TFOE with ex vivo brain slice electrophysiology,we unveil cell-type-specific responses of excitatory and inhibitory neurons to acoustic stimulation.These results demonstrate that TFOE is a non-genetic single-cell and sub-cellular modulation technology,which could shed new insights into the mechanism of ultrasound neurostimulation. | Linli Shi Ying Jiang Fernando R.Fernandez Guo Chen Lu Lan Heng-Ye Man John A.White Ji-Xin Cheng Chen Yang | 2021 | Light(Science & Applications)2021，10，8： | 4 |
| 4 | Microbiome and ileum transcriptome revealed the boosting effects of selenium yeast on egg production in aged laying hens显示文摘The declines in laying performance during the late productionperiod have adverse effects on the length of theproduction cycle. Improving the nutrition of laying hens is a crucialmeasure to reverse this declination. Thisstudy investigatedthe effect of seleniumyeast (SY)on egg production, ileal gene expressionandmicrobiota, aswell as elucidating their associations in aged laying hens. A total of 375 Jinghong laying hens at 76weeks oldwere randomly assigned into 5 dietary treatments, which included a selenium-deficient basal diet based oncorn-soybean meal, and dietary supplementation of SY at 0.15, 0.30 and 0.45 mg/kg, and sodium selenite at0.45mg/kg.The results showed that SYamelioratedthe depressionin aged layingperformance inthe 0.30mg/kg group (P < 0.01). Selenium yeast significantly increased ileum selenium concentration (P < 0.05), and SYgroups had higher seleniumdeposition efficiency than the sodiumselenite group. Functional enrichment andShort Time-series Expression Miner (STEM) analysis indicated that SY activated metabolic progress (e.g.,glycerolipidmetabolism, glycerophospholipidmetabolism, andfattyacidmetabolism),immune responseandoxidative stress response. Four hub genes including thioredoxin reductase 1 (TXNRD1), dihydrolipoamidedehydrogenase (DLD), integrin linked kinase (ILK) and leucine zipper tumor suppressor 2 (LZTS2) wereinvolved in intestinal metabolismwhich was closely associated with selenium deposition/status. Moreover,the relative abundance of Veillonella, Turicibacter and Lactobacillus was significantly increased, but the relativeabundance of Stenotrophomonas was significantly decreased by SY supplementation. Multi-omics dataintegration and Canonical correspondence analysis (CCA) showed that both the ileumselenium content andthe laying rate were highly correlated with pathways and bacteria enriched in metabolism and immuneresponse. Meanwhile, the “switched on” gene prostate stem cell antigen (PSCA) had a positive relationshipwith Veillonella and a negative relationship with the opportunistic pathogens Stenotrophomonas. Overall, ourstudy offered insight for the further exploration of the role of SY on boosting egg production and balancingileum intestinal flora in aged laying hens. | Zhexi Liu Yutao Cao Yue Ai Xiaonan Yin Linli Wang Mengyao Wang Bingkun Zhang Zhengxing Lian Keliang Wu Yuming Guo Hongbing Han | 2022 | Animal Nutrition2022，，3： | 3 |
| 5 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 6 | Ternary ZnO/Co_(3)O_(4)/NiO inherited layered core-shell structure from a double template for high performanced supercapacitor显示文摘Relying on seed method,a double template ZIF-8@ZIF-67 with a layered core-shell structure was made,which is used as a sacrificial template in the next steps.After going through loading process with solvent thermal method and calcination process,ZIF-8@ZIF-67 was etched and calcined into ternary ZnO/Co_(3)O_(4)/NiO successfully.Besides,benefiting from right amount of the addition of inorganic salts,the optimized ZnO/Co_(3)O_(4)/NiO-2(ZCN-2)shows the outstanding performance in its morphologic structure and electrochemical performance.In the case of a current density of 1 Ag^(-1),the high specific capacitance of 1119.11 Cg^(-1) can be calculated in ZCN-2.In addition,at 10 Ag^(-1),the capacitance value can maintain 93.75%after experiencing 5000 cycles of charging and discharging.The maximum energy density of the assembled ZCN-2//activated carbon(AC)asymmetric supercapacitor can reach 95.82 Wh kg^(-1),which is really outstanding in the present research achievements.After experiencing charge-discharge cycles with the number of 10,000 times in the case of a current density of 10 Ag^(-1),the cycling stability of this supercapacitor can reach 94.53%of the initial value.And after a charge,the device connected by two supercapacitors can make a light emitting diode(LED)shine up to 30 min successfully. | Linli Zhu Chen Hao Saisai Zhou Xiaohong Wang Tiantian Zhou Yaning Guo | 2021 | Journal of Materiomics2021，7，4： | 1 |
| 7 | Optically-generated focused ultrasound for noninvasive brain stimulation with ultrahigh precision显示文摘High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological diseases.Current non-invasive neuromodulation methods offer limited precision at the milimeter level.Here,we report opticallygenerated focused ultrasound(OFUS)for non-invasive brain stimulation with ultrahigh precision.OFUS is generated by a soft optoacoustic pad(SOAP)fabricated through embedding candle soot nanoparticles in a curved polydimethylsiloxane film.SOAP generates a transcranial ultrasound focus at 15 MHz with an ultrahigh lateral resolution of 83μm,which is two orders of magnitude smaller than that of conventional transcranial-focused ultrasound(tFUS).Here,we show effective OFUS neurostimulation in vitro with a single ultrasound cycle.We demonstrate submillimeter transcranial stimulation of the mouse motor cortex in vivo.An acoustic energy of 0.6 mJ/cm?,four orders of magnitude less than that of tFUS,is suffcient for successful OFUS neurostimulation.OFUS offers new capabilities for neuroscience studies and disease treatments by delivering a focus with ultrahigh precision noninvasively. | Yueming Li Ying Jiang Lu Lan Xiaowei Ge Ran Cheng Yuewei Zhan Guo Chen Linli Shi Runyu Wang Nan Zheng Chen Yang Ji-Xin Cheng | 2022 | Light(Science & Applications)2022，11，11： | 1 |
| 8 | MiR-203 is downregulated in laryngeal squamous cell carcinoma and can suppress proliferation and induce apoptosis of tumours显示文摘 | Linli Tian Minghua Li Jingchun Ge Yan Guo Yanan Sun Ming Liu Hui Xiao | 2014 | Tumor Biology2014，，6： | 1 |
| 9 | Influence of Mg^2+ and Cd^2+ on the interaction between sparfloxacin and calf thymus DNA 显示文摘 | YUAN Xiaoying GUO Dongsheng WANG Linli | 2008 | Spectrochim Acta A2008，69，： | 1 |
| 10 | Generating homozygous mutant populations of barley microspores by ethyl methanesulfonate treatment显示文摘Induced mutations are important for genetic research and breeding.Mutations induced by physical or chemical mutagenesis are usually heterozygous during the early generations.However,mutations must be fixed prior to phenotyping or field trials,which requires additional rounds of self-pollination.Microspore culture is an effective method to produce double-haploid(DH)plants that are fixed homozygotes.In this study,we conducted ethyl methanesulfonate(EMS)-induced mutagenesis of microspore cultures of barley(Hordeum vulgare)cultivar‘Hua30’and landrace‘HTX’.The EMS concentrations were negatively correlated with the efficiency of callus induction and the frequency of mutant plant regeneration.The two genotypes showed different regeneration efficiencies.The phenotypic variation of the regenerated M1 plants and the presence of genome-wide nucleotide mutations,revealed by whole-genome sequencing,highlight the utility of EMS-induced mutagenesis of isolated microspore cultures for developing DH mutants.Genome-wide analysis of the mutation frequency in the regenerated plants revealed that a considerable proportion of mutations resulted from microspore culture(somaclonal variation)rather than EMS-induced mutagenesis.In addition to producing a population of 1972 homozygous mutant lines that are available for future field trials,this study lays the foundation for optimizing the regeneration efficiency of DH plants and the richness of mutations(mainly by fine-tuning the mutagen dosage). | Linli Huang Guangqi Gao Congcong Jiang Guimei Guo Qiang He Yingjie Zong Chenghong Liu Ping Yang | 2023 | aBIOTECH2023，4，3： | 0 |
| 11 | Karst Cave as Terrestrial Simulation Platform to Test and Design Human Base in Lunar Lava Tube显示文摘Developing efficient approaches to building a suitable environment for humans on the moon play a key role in future long-term sustainable lunar exploration activities,which has motivated many countries to propose diverse plans to build a lunar base.The lava tubes discovered by the Kaguya mission offer huge potential sites to host such bases.Through computation and analysis,we show that lunar lava tubes offer stable structures,suitable temperatures,low radiation doses,and low meteorite impact rates.We summarize previous research results and put forward the conditions to find and use a suitable lunar lava tube for human habitation on the moon.The establishment of extraterrestrial bases still faces many technical bottlenecks;many countries have begun to use the earth’s environment for extraterrestrial exploration and simulation missions.In this regard,we proposed the idea of using the Earth’s karst caves to simulate extraterrestrial lava tubes,selected caves in Chongqing as the simulation site,and demonstrated the feasibility from both structural and environmental aspects.Finally,we proposed a karst cave simulation platform with three main research directions:cave sealing technology,efficient daylight system,and internal circulation research of artificial ecosystems containing natural soil and rock.We hope to promote the development of related research on extraterrestrial bases through simulation experiments. | Jinghang Ding Gengxin Xie Linli Guo Xin Xiong Ya Han Xi Wang | 2022 | Space(Science & Technology)2022，，1： | 0 |
| 12 | Phytohormones Accumulation and Distribution in Shoots and Roots of Haploid,Diploid and Tetraploid Barley Seedlings Derived from Microspore Culture显示文摘Phytohormones play important roles in plant growth and development,and polyploids are thought to be an important method for plant breeding.However,the relationship between ploidy and phytohormone is still unclear.In this study,barley at three ploidy levels were produced by microspore culture.Therefore,we further analyzed the phytohormone content in the shoots and roots of the three kinds of barley materials to study the effect of ploidy on phytohormones accumulation and distribution.The results showed that Abscisic acid(ABA),gibberellin(GA),jasmonic acid(JA),auxin(IAA),salicylic acid(SA)and cytokinin(CTK)were successfully determined in shoots and roots using LC-MS(liquid chromatography mass spectrometry).By comparing the shoots of the haploid and diploid plants,it was found that the distribution trend of the six phytohormones was consistent,and another consistent trend was found in the roots of the diploid and tetraploid plants.In addition,we further analyzed the shoot/root ratio of the different phytohormones to identify the potential differences for haploid,diploid and tetraploid.Here,the relationship between ploidy and phytohormone we provided would provide new insights into understanding the new phenotypes that occur in polyploid species. | Longhua Zhou Ting He Jing Li Guimei Guo Yingbo Li Hongwei Xu Runhong Gao Linli Huang Yifei Wang Ruiju Lu Zhiwei Chen Chenghong Liu | 2022 | Phyton-International Journal of Experimental Botany2022，91，7： | 0 |
| 13 | Co-seismic groundwater-level and temperature changes of the 2011 Mw9. 0 Japan earthquake in Chinese mainland显示文摘Co-seismic groundwater-level and temperature changes caused by the Mw9. 0 Japan earthquake in Chinese mainland are described. The recorded water-level changes were mostly oscillations,with some step decreases mostly in the coastal area of Southeast China and step increases mostly in Northeast China and the North-South Seismic Belt. The water-temperature changes were mainly decrease with slow recovery in Sichuan-Yunnan,South China,and lower reaches of Jiangzhong,and sharp increase followed by sharp decrease,or vice versa,in North China and Northeast China. For wells that showed step changes in both water level and temperature,more showed them in the same direction than in the opposite direction. | Luo Junqiu Sun Linli Zhang Weihua Li Ming Guo Xizhi | 2011 | Geodesy and Geodynamics2011，2，4： | 0 |
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