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| 1 | 中国1960-2016年风能资源的时空分布特征显示文摘基于462个气象观测站1960–2016年共57年的近地面风速日资料,利用克里格空间内插,最小二乘法,相关系数检验和经验正交函数分解(EOF)等方法分析了年均和各个季节中国区域风速及有效风能密度的时空变化特征。研究结果表明:在中国北部和部分沿海地区年平均风速在3 m s-1以上,有效风能密度在75 W m-2以上,而在中国南部地区平均风速和有效风能密度均较小。近五十多年以来,中国区域年均和季节平均风速呈明显下降趋势,北部地区春季递减率最大,沿海地区冬季递减率最大。广东部分地区年平均风速有增大的趋势,西南,华南和华中西部地区年平均风速变化不大。平均风速大的区域,递减率也大。年平均风速和年有效风能密度的主要空间分布模态表现出高度的一致性,均呈现逐年减小趋势。中国风速及风能资源的减小趋势,主要与全球变暖及土地利用变化有关。 | FENG Yucheng QUE Linjing FENG Jinming | 2020 | Atmospheric and Oceanic Science Letters2020,13,2: | 5 |
| 2 | Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study显示文摘 | Chunping Wang Yinying Lu Yan Chen Yongyi Feng Linjing An Xinzhen Wang Shuhui Su Wenlin Bai Lin Zhou Yongping Yang Dongping Xu | 2009 | Clinical & Experimental Metastasis2009,,7: | 1 |
| 3 | Spinel/Layered Heterostructured Cathode Material for High‐Capacity and High‐Rate Li‐Ion Batteries显示文摘 | Feng Wu Ning Li Yuefeng Su Haofang Shou Liying Bao Wen Yang Linjing Zhang Ran An Shi Chen | 2013 | Adv Mater2013,,27: | 1 |
| 4 | Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study显示文摘 | Chunping Wang Yinying Lu Yan Chen Yongyi Feng Linjing An Xinzhen Wang Shuhui Su Wenlin Bai Lin Zhou Yongping Yang Dongping Xu | 2009 | Clinical & Experimental Metastasis2009,,7: | 1 |
| 5 | 显示文摘 | Li Xiang Linjing Shen Feng Long | 2011 | Macromolecular Chem- istry and Physics2011,212,6: | 1 |
| 6 | Correction To:Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARSCoV-2 variants显示文摘Correction to:Signal Transduction and Targeted Therapy http://gffzzd3cc09b8251d45dfsqbwn6609o9no65xb.ffgz.tsg.suse.edu.cn/10.1038/s41392-023-01423-6,published online 17 April 2023 After online publication of the article^(1),the authors noticed two inadvertent mistakes occurred in References that needs to be corrected.The correct text is provided as follows. | Qian Wang Chenchen Yang Li Yin Jing Sun Wei Wang Hengchun Li Zhengyuan Zhang Si Chen Bo Liu Zijian Liu Linjing Shi Xiaolin Liu Suhua Guan Chunhua Wang Linbing Qu Ying Feng Xuefeng Niu Liqiang Feng Jincun Zhao Pingchao Li Ling Chen Nanshan Zhong | 2023 | Signal Transduction and Targeted Therapy2023,8,6: | 1 |
| 7 | A symmetric image encryption approach based on line maps显示文摘 | Feng Yong Li Linjing Huang Feng | 2006 | ISSCAA2006,1,: | 1 |
| 8 | The SMAD2/miR-4256/HDAC5/p16^(INK4a) signaling axis contributes to gastric cancer progression显示文摘The dysregulation of exosomal microRNAs(miRNAs)plays a crucial role in the development and progression of cancer.This study investigated the role of a newly identified serum exosomal miRNA miR-4256 in gastric cancer(GC)and the underlying mechanisms.The differentially expressed miRNAs were firstly identified in serum exosomes of GC patients and healthy individuals using next-generation sequencing and bioinformatics.Next,the expression of serum exosomal miR-4256 was analyzed in GC cells and GC tissues,and the role of miR-4256 in GC was investigated by in vitro and in vivo experiments.Then,the effect of miR-4256 on its downstream target genes HDAC5/p16^(INK4a) was studied in GC cells,and the underlying mechanisms were evaluated using dual luciferase reporter assay and Chromatin Immunoprecipitation(ChIP).Additionally,the role of the miR-4256/HDAC5/p16^(INK4a) axis in GC was studied using in vitro and in vivo experiments.Finally,the upstream regulators SMAD2/p300 that regulate miR-4256 expression and their role in GC were explored using in vitro experiments.miR-4256 was the most significantly upregulated miRNA and was overexpressed in GC cell lines and GC tissues;in vitro and in vivo results showed that miR-4256 promoted GC growth and progression.Mechanistically,miR-4256 enhanced HDAC5 expression by targeting the promoter of the HDAC5 gene in GC cells,and then restrained the expression of p16^(INK4a) through the epigenetic modulation of HDAC5 at the p16INK4a promoter.Furthermore,miR-4256 overexpression was positively regulated by the SMAD2/p300 complex in GC cells.Our data indicate that miR-4256 functions as an oncogene in GC via the SMAD2/miR-4256/HDAC5/p16^(INK4a) axis,which participates in GC progression and provides novel therapeutic and prognostic biomarkers for GC. | MIN WANG HAILIANG ZHAO WEIWEI CHEN CAIQUN BIE JINYING YANG WENRUI CAI CHUTIAN WU YANFANG CHEN SHUFEN FENG YING SHI YUTING LI HUIJUN TANG LIXIAN ZHONG LILIANGZI GUO SISI CHEN LINJING LONG SHAOHUI TANG | 2023 | Oncology Research2023,31,4: | 0 |
| 9 | Intercellular mitochondrial transfer as a means of tissue revitalization显示文摘As the crucial powerhouse for cell metabolism and tissue survival,the mitochondrion frequently undergoes morphological or positional changes when responding to various stresses and energy demands.In addition to intracellular changes,mitochondria can also be transferred intercellularly.Besides restoring stressed cells and damaged tissues due to mitochondrial dysfunction,the intercellular mitochondrial transfer also occurs under physiological conditions.In this review,the phenomenon of mitochondrial transfer is described according to its function under both physiological and pathological conditions,including tissue homeostasis,damaged tissue repair,tumor progression,and immunoregulation.Then,the mechanisms that contribute to this process are summarized,such as the trigger factors and transfer routes.Furthermore,various perspectives are explored to better understand the mysteries of cell-cell mitochondrial trafficking.In addition,potential therapeutic strategies for mitochondria-targeted application to rescue tissue damage and degeneration,as well as the inhibition of tumor progression,are discussed. | Delin Liu Youshui Gao Jiao Liu Yigang Huang Junhui Yin Yuyao Feng Linjing Shi Bruno PMeloni Changqing Zhang Minghao Zheng Junjie Gao | 2021 | Signal Transduction and Targeted Therapy2021,6,3: | 0 |
| 10 | Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARS-CoV-2 variants显示文摘The highly contagious SARS-CoV-2 Omicron subvariants severely attenuated the effectiveness of currently licensed SARS-CoV-2 vaccines based on ancestral strains administered via intramuscular injection.In this study,we generated a recombinant,replication-incompetent human adenovirus type 5,Ad5-S-Omicron,that expresses Omicron BA.1 spike.Intranasal,but not intramuscular vaccination,elicited spike-specific respiratory mucosal IgA and residential T cell immune responses,in addition to systemic neutralizing antibodies and T cell immune responses against most Omicron subvariants.We tested intranasal Ad5-S-Omicron as a heterologous booster in mice that previously received intramuscular injection of inactivated ancestral vaccine.In addition to inducing serum broadly neutralizing antibodies,there was a significant induction of respiratory mucosal IgA and neutralizing activities against Omicron subvariants BA.1,BA.2,BA.5,BA.2.75,BF.7 as well as pre-Omicron strains Wildtype,Beta,and Delta.Serum and mucosal neutralizing activities against recently emerged XBB,BQ.1,and BQ.1.1 could also be detected but were much lower.Nasal lavage fluids from intranasal vaccination contained multimeric IgA that can bind to at least 10 spike proteins,including Omicron subvariants and pre-Omicron strains,and possessed broadly neutralizing activities.Intranasal vaccination using Ad5-S-Omicron or instillation of intranasal vaccinee’s nasal lavage fluids in mouse nostrils protected mice against Omicron challenge.Taken together,intranasal Ad5-S-Omicron booster on the basis of ancestral vaccines can establish effective mucosal and systemic immunity against Omicron subvariants and multiple SARS-CoV-2 variants.This candidate vaccine warrants further development as a safe,effective,and user-friendly infection and transmission-blocking vaccine. | Qian Wang Chenchen Yang Li Yin Jing Sun Wei Wang Hengchun Li Zhengyuan Zhang Si Chen Bo Liu Zijian Liu Linjing Shi Xiaolin Liu Suhua Guan Chunhua Wang Linbing Qu Ying Feng Xuefeng Niu Liqiang Feng Jincun Zhao Pingchao Li Ling Chen Nanshan Zhong | 2023 | Signal Transduction and Targeted Therapy2023,8,5: | 0 |
| 11 | Can Turbulent, High-density Gas Form Stars in Molecular Clouds: A Case Study in Ophiuchus显示文摘Star formation is governed by the interplay between gravity and turbulence in most of molecular clouds.Recent theoretical works assume that dense gas,whose column density is above a critical value in the column density probability distribution function(N-PDF),where gravity starts to overcome turbulence,becomes star-forming gas and will collapse to form stars.However,these high-density gases will include some very turbulent areas in the clouds.Will these dense but turbulent gases also form stars?We test this scenario in Ophiuchus molecular cloud using N-PDF analysis and find that at least in some regions,the turbulent,dense gas is not forming stars.We identified two isolated high-density structures in Ophiuchus,which are gravitationally unbound and show no sign of star formation.Their high densities may come from turbulence. | Sihan Jiao Jingwen Wu Hao Ruan Yuxin Lin Chao-Wei Tsai Linjing Feng | 2022 | Research in Astronomy and Astrophysics2022,22,7: | 0 |