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| 1 | Synergistic and feedback signaling mechanisms in the regulation of inflammation in respiratory infections显示文摘肺病,最典型、经常的更低的呼吸的道感染(LRTI ) ,是在美国的健康问题的一个领先的原因。细菌在孩子和成年人代表肺病的大多数占优势的原因。尽管有单个细菌的感染的肺病是普通的,有肺病的病人的重要部分是 polymicrobial。这感染经常是有象 cytokines 那样的另外的生理的因素和生长因素的 complexed。Nontypeable Haemophilus influenzae (NTHi ) 是在呼吸系统的最经常恢复的克否定的细菌的病原体并且导致强壮的煽动性的回答。NTHi 另外有另外的呼吸病原体的 synergizes 例如链球菌 pneumoniae 和呼吸病毒和支持 inflammatory cytokines,例如肿瘤坏死 factor-alpha (TNF-α) 。它是引人注目的那 NTHi 不仅有象转变生长因素贝它那样的生长因素的 synergizes (TGF-β) ,而且利用象 TGF-β 那样的生长因素受体;受体和表皮的生长因素受体(EGFR ) ,提高煽动性的回答。尽管适当发炎是对入侵病原体的保护的回答,不受管束的煽动性的回答对主人经常有害。因此,发炎必须紧被调整。人的免疫系统为控制 overactive 发展了策略煽动性的反应。一如此的重要机制经由为发炎的否定反馈管理者的规定。CYLD,多功能的 deubiquitinase,是原来作为肿瘤 suppressor 报导了,但是最近为原子 factor-kappa B 作为一个否定管理者被识别(NF-κ B ) 发信号。它被 NTHi 和 TNF-α 导致;经由 NF-κ B 依赖的机制,从而为紧在 NTHi 感染控制发炎用作一个可诱导的否定反馈管理者。 | Wenzhuo Y Wang Jae Hyang Lim Jian-Dong Li | 2012 | Cellular & Molecular Immunology2012，9，2： | 10 |
| 2 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | The Lancet . 2012 (9859)2012，，9859： | 7 |
| 3 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | The Lancet2012，，9859： | 5 |
| 4 | Laparoscopic resection of gastrointestinal stromal tumors:Does laparoscopic surgery provide an adequate oncologic resection?显示文摘Gastrointestinal stromal tumors (GISTs) are rare tumors of the GI tract.Surgical resection remains the mainstay of non-metastatic disease.However,the ability to provide an adequate oncologic resection using laparoscopic surgery is still an area of debate.This is a thorough review of the current literature,looking particularly at the use of laparoscopic surgery for larger GISTs and the long-term oncologic outcomes compared to the results of open surgery.Laparoscopic resections provide an adequate oncologic result for GISTs of all sizes,including those greater than 5 cm in size. | Joseph J Kim James Y Lim Scott Q Nguyen | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 3 |
| 5 | 评估内燃机隔振系统功率流传递的一种新模型(英文)显示文摘为准确评估弹性复杂隔振基础条件下振动内燃机的功率流传递水平,采用Mindlin板替代传统的Kirchihoff薄板,建立了一种涵盖多种隔振基础形式的普适模型。运用子结构技术和变分理论,推导了隔振系统的控制方程以及传递到较厚甚至不同配置方式的各向异性复杂梁式基础的功率流。与基于各向同性薄板基础的传统模型相比较,研究了普适隔振系统功率流的传递特性。仿真研究表明,所提模型是有效的,可得到比传统模型更加准确的结果。 | 牛军川 葛培琪 林志华 梁以德 宋孔杰 LIM C W LEUNG A Y T | 2009 | 内燃机学报2009，27，1： | 3 |
| 6 | 与GNA11体细胞突变相关的先天性血管瘤和先天性血管瘤病显示文摘先天性血管瘤是一种罕见的良性血管性肿瘤,出生时即被发现,常呈孤立型。该文作者报高1例男性患儿,出生时即发现巨大血管性肿物,并伴发贫血、血小板减少及广泛的凝血障碍,皮肤见大量散在的小血管丘疹。手术切除后,标本进行免疫组织化学及基因检测。 | Funk T Lim Y Kulungowski AM | 2016 | 中国口腔颌面外科杂志2016，14，5： | 3 |
| 7 | Age-related macular degeneration显示文摘 | Laurence S Lim Paul Mitchell Johanna M Seddon Frank G Holz Tien Y Wong | 2012 | The Lancet . 2012 (9827)2012，，9827： | 2 |
| 8 | Immunogenicity of the E1E2 proteins of hepatitis C virus expressed by recombinant adenoviruses 显示文摘 | Seong Y R Choi S Lim J S | 2001 | Vaccine2001，19，2022： | 2 |
| 9 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | 2012 (9859)2012，，9859： | 2 |
| 10 | Effect of carbon nanotube addition on tribological behavior of UHMWPE显示文摘 | Zoo Y S An J W Lim D P | 2004 | Tribology Letters2004，16，： | 1 |
| 11 | Type studies on Phellinus baumii and Phellinus linte us 显示文摘 | LIM Y W LEE J S JUNG H S | 2003 | Mycotaxon2003，，85： | 1 |
| 12 | Inhibition of cell-cycle progression in HeLa cells by HY52, a novel cyclin-dependent kinase inhibitor isolated from Bauhinia forficata显示文摘 | Lim H Kim MK Lim Y | 2006 | Cancer Lett2006，233，1： | 1 |
| 13 | Antioxidant activities of isoflavones from the rhizomes of Belamcanda chinensis on carbon tetrachloride-induced hepatic injury in rats显示文摘 | Jung S H Lee Y S Lim S S | 2004 | Arch Pharm Res2004，27，2： | 1 |
| 14 | Infiuence of admission body temperature on stroke mortality显示文摘 | Lim LL Levi C | 2000 | Stroke2000，31，2： | 1 |
| 15 | Synthesis and properties of semifluorinated block copolymers containing poly(ethylene oxide) and poly(fluorooctyl methacrylates) via atom transfer radical polymerization显示文摘 | Lee M Y Moon M J | 2002 | Polymer2002，43，： | 1 |
| 16 | Improving amplify-and-forward relay networks: optimal power allocation versus selection 显示文摘 | Zhao Y Adve R Lim T | 2007 | IEEE Trans on Wireless Communications2007，6，8： | 1 |
| 17 | Growth process of β-FeSi2 epitaxial film on Si(Ⅲ) by molecular beam epitaxy显示文摘 | Ji S Y Wang J F Lim J W | 2006 | Applied Surface Science2006，253，2： | 1 |
| 18 | Ions released from dental amalgams in contact with titanium显示文摘 | Lim S Takada Y Kiln K | 2003 | Dent Mater J2003，22，1： | 1 |
| 19 | TGF-beta1 induces cardiac hypertrophic responses via PKC-dependent ATF-2 activation显示文摘 | LIM J Y PARK S J HWANG H Y | 2005 | J Mol Cell Cardiol2005，39，4： | 1 |
| 20 | Research frontier: memetic computation-past,present & future 显示文摘 | ONG Y S LIM M H CHEN Xian-shun | 2010 | IEEE Computational Intelli- gence Magazine2010，5，2： | 1 |
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