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| 1 | Anisotropic damage coupled modeling of saturated porous rock显示文摘It is widely acknowledged that the natural rock mass is anisotropic and its failing type is also non-isotropic. An orthotropic elastic damaged model has been proposed in which the elastic deformation,the damaged deformation and irreversible deformation can be identified respectively. A second rank damage tensor is employed to characterize the induced damage and damage evolution related to the propagation conditions of microcracks. A specific form of the Gibbs free energy function is used to obtain the effective elastic stiffness and the limited scopes of damage parameters are suggested. The model’s parameter determination is proposed by virtue of conventional tri-axial test. Then,the proposed model is developed to simulate the coupled hydraulic mechanical responses and traction behaviors in different loading paths of porous media. | LU YingFa1,2, WU XinXing1,2 & SHAO JianFu3 1 Key Laboratory of Geological Hazards on Three Gorges Reservoir Area, Ministry of Education, China Three Gorges University, Yichang 443002, China 2 School of Civil Engineering, Wuhan University, Wuhan 430071, China 3 University of Sciences and Technologies of Lille, Lille 59655, France | 2010 | Science China(Technological Sciences)2010，53，10： | 5 |
| 2 | 高发地区结核病传播模式:空间聚集性分析显示文摘背景:Cape Town市Ravensmead和Uitsig郊区的结核病流行严重,1996年的肺结核报告率为1340/10万。这些市郊的特点是人口稠密、失业率高、贫穷严重。传统认为结核病传播主要发生在与传染源有密切接触的家庭内。但近年来的研究则将结核病传播与家庭外的某些场所联系起来,而这些场所与高危生活方式有关。在CaPe Town市郊区进行的人类学研究确认了大量的饮酒场所(酒吧)(17/平方公里),这提示群体性饮酒已经成为一种特殊生活方式的一部分。 目的:应用地理信息系统(GIS)研究结核病传播的场所及影响因素。结果和结论:应用探索性疾病地图的空间流行病学技术,对1993—1998年间经细菌学确诊的1128例肺结核进行了研究。点分布模式分析结果和空间聚集性统计量都提示高发地区的肺结核存在聚集性。结核病报告率与失业、人口稠密以及研究地区的酒吧密度存在显著的相关性。其中,高肺结核病报告率与失业及其导致的贫穷之间的联系最为显著。 | Z.Munch S.W.P.Van Lill C.N.Booysen H.L.Zietsman D.A.Enarson N.Beyers 屠德华 | 2003 | 国际结核病与肺部疾病杂志2003，，2： | 4 |
| 3 | Therapeutic effects of human amniotic epithelial cell transplantation on double-transgenic mice co-expressing APPswe and PS1ΔE9-deleted genes显示文摘Human amniotic epithelial cells (HAECs), which exhibit characteristics of embryonic and pluripotent stem cells, could be utilized for cell therapy without legal or ethical problems. Double-transgenic (TG) mice (n=20) and wild-type (WT) mice (n=20) were randomly assigned to two groups, respectively. The transplantation group was treated with HAECs and the control group with PBS. A six-radial arm water maze was used to assess spatial memory. Immunofluorescence was utilized to track HAEC survival. Immunohistochemistry was used to determine octamer-binding protein 4 (oct-4) and nanog expression in the HAECs. High-performance liquid chromatography (HPLC) was used to measure acetylcholine levels in the hippocampus. The density of cholinergic neurons in the basal forebrain and nerve fibers in the hippocampus was measured following acetylcholinesterase staining. Results showed that transplanted HAECs survived for at least eight weeks and migrated to the third ventricle without immune rejection. Graft HAECs also expressed the specific stem cell markers oct-4 and nanog. Compared with the control group, HAEC transplantation significantly ameliorated spatial memory deficits in TG mice, as well as increased acetylcholine levels and the number of hippocampal cholinergic neurites. Intracerebroventricular HAEC transplantation improved spatial memory in double-TG mice, and results suggested that increased acetylcholine levels in the hippocampus, released by surviving cholinergic neurites, were responsible for this improvement. | XUE ShouRu CHEN ChongFang DONG WanLi HUI GuoZhen LIU TianJun GUO Lille | 2012 | Science China(Life Sciences)2012，55，2： | 3 |
| 4 | Treatment strategies for proximal femur fractures in osteoporotic patients显示文摘 | Felix Bonnaire Henry Zenker Christoph Lill Andreas T. Weber Berend Linke | 2005 | Osteoporosis International2005，，2： | 2 |
| 5 | Combination of low vascular endothelial growth factor A (VEGF‐A)/VEGF receptor 2 expression and high lymphocyte infiltration is a strong and independent favorable prognostic factor in patients with nonsmall cell lung cancer显示文摘 | TomDonnem KhalidAl‐Shibli SigveAndersen SamerAl‐Saad Lill‐ToveBusund Roy M.Bremnes | 2010 | Cancer2010，，18： | 2 |
| 6 | 3,5-diiodo- l -thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet显示文摘 | Maria Pina Mollica Lillà Lionetti Maria Moreno Assunta Lombardi Pieter De Lange Alessandro Antonelli Antonia Lanni Gina Cavaliere Antonio Barletta Fernando Goglia | 2009 | Journal of Hepatology2009，，2： | 2 |
| 7 | Proximal humeral fractures: how stiff should an implant be?显示文摘 | H. Lill P. Hepp J. Korner J.-P. Kassi A. P. Verheyden C. Josten G. N. Duda | 2003 | Archives of Orthopaedic and Trauma Surgery (-)2003，，2： | 2 |
| 8 | The angle stable locking-proximal-humerus-plate (LPHP) for proximal humeral fractures using a small anterior lateral deltoid splitting approach technique and first results显示文摘 | Lill H Hepp P Rose T | 2004 | Zentralbl Chir2004，129，1： | 1 |
| 9 | Proximal humeral fractures:how stiff shoul danim plantbe?Acom parative mechanical study with newimplantin humans pecimens显示文摘 | Lill H Hepp P Korner J et al | 2003 | Arch Orthop Trauma Surg2003，123，23： | 1 |
| 10 | Impact of pretreatment and freezing conditions on the microstructure of frozen carrots:quantification and relation to texture loss 显示文摘 | Buggenhout V Lille M Messagie I | 2006 | European Food Research and Technology2006，222，56： | 1 |
| 11 | The antibiotic ADEP reprogrammes CIpP, switching it from a regulated to an uncontrolled pmtease显示文摘 | Kirstein J Hoffmann A Lille H | 2009 | EMBO Mol Med2009，1，1： | 1 |
| 12 | The Locking-proximal- humerus-plate (LPHP) for proximal humeral fractures using a small anterlor-lateral-del approach-techniq toid-splitting- ue and first results 显示文摘 | Lill H Hepp angle stable P Rose T | 2004 | Zentralbl CMr2004，129，： | 1 |
| 13 | Treatment strategies for proximal femur fractures in osteoporotic patients显示文摘 | Bonnaire F Zenker H Lill C | | 0，，2： | 1 |
| 14 | Effect of high pressure processing on colour, texture and flavor of fruit and vegetable-based food products:a review显示文摘 | Oey I Lille M Loey A V | 2008 | Trends in Food Science and Technology2008，19，6： | 1 |
| 15 | Distal humerus fractures in elderly patients:Results after open reduction and internal fixation显示文摘 | Lill H Muller LP Hessmann M | 2005 | Osteoporos Int2005，，： | 1 |
| 16 | The ability of currently available stress-breaking elements for osseointegrated implants to imitate natural tooth mobility显示文摘 | | 1988 | Int J Oral Maxillofac Implants1988，3，： | 1 |
| 17 | Where should implants be anchored in the humeral head?显示文摘 | Hepp P Lill H Bail H | 2003 | Clin Orthop Relat Res2003，，415： | 1 |
| 18 | T plate osteosynthesis in dislocation proximal humerus fractures 显示文摘 | LILL H IANGE K PRASSE BADDE J | 1997 | Unfallchirurgic1997，23，5： | 1 |
| 19 | Treatment strategies for proxi- mal femur fractures in osteoporotic patients显示文摘 | Bonnaire F Zenker H Lill C | 2005 | Osteoporos Int2005，16，2： | 1 |
| 20 | Proximal humeral fractures : how stiff should an implantbe? A comparative mechanical study with new implants in human specimens显示文摘 | Lill H Hepp P Kornar J | 2003 | Arch Orthop Trauma Surg2003，123，23： | 1 |
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