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| 1 | The Genome Sequence Archive Family: Toward Explosive Data Growth and Diverse Data Types显示文摘The Genome Sequence Archive(GSA)is a data repository for archiving raw sequence data,which provides data storage and sharing services for worldwide scientific communities.Considering explosive data growth with diverse data types,here we present the GSA family by expanding into a set of resources for raw data archive with different purposes,namely,GSA(http://gffzz77e3413bc06540eds0qwb9ckuokq96ucu.ffgz.tsg.suse.edu.cn/gsa/),GSA for Human(GSA-Human,http://gffzz77e3413bc06540eds0qwb9ckuokq96ucu.ffgz.tsg.suse.edu.cn/gsa-human/),and Open Archive for Miscellaneous Data(OMIX,http://gffzz77e3413bc06540eds0qwb9ckuokq96ucu.ffgz.tsg.suse.edu.cn/omix/).Compared with the 2017 version,GSA has been significantly updated in data model,online functionalities,and web interfaces.GSA-Human,as a new partner of GSA,is a data repository specialized in human genetics-related data with controlled access and security.OMIX,as a critical complement to the two resources mentioned above,is an open archive for miscellaneous data.Together,all these resources form a family of resources dedicated to archiving explosive data with diverse types,accepting data submissions from all over the world,and providing free open access to all publicly available data in support of worldwide research activities. | Tingting Chen Xu Chen Sisi Zhang Junwei Zhu Bixia Tang Anke Wang Lili Dong Zhewen Zhang Caixia Yu Yanling Sun Lianjiang Chi Huanxin Chen Shuang Zhai Yubin Sun Li Lan Xin Zhang Jingfa Xiao Yiming Bao Yanqing Wang Zhang Zhang Wenming Zhao | 2021 | Genomics, Proteomics & Bioinformatics2021，19，4： | 38 |
| 2 | Reduction-induced interface reconstruction to fabricate MoNi_(4) - based hollow nanorods for hydrazine oxidation assisted energysaving hydrogen production in seawater显示文摘Seawater electrolysis could address the water scarcity issue and realize the grid-scale production of carbon-neutral hydrogen,while facing the challenge of high energy consumption and chloride corrosion.Thermodynamically more favorable hydrazine oxidation reaction(HzOR)assisted water electrolysis is efficiency for energy-saving and chlorine-free hydrogen production.Herein,the MoNi alloys supported on MoO_(2) nanorods with enlarged hollow diameter on Ni foam(MoNi@NF)are synthesized,which is constructed by limiting the outward diffusion of Ni via annealing and thermal reduction of NiMoO_(4) nanorods.When coupling HzOR and hydrogen evolution reaction(HER)by employing MoNi@NF as both anode and cathode in two-electrode seawater system,a low cell voltage of 0.54 V is required to achieve 1,000 mA·cm^(−2) and with long-term durability for 100 h to keep above 100 mA·cm^(−2) and nearly 100%Faradaic efficiency.It can save 2.94 W·h to generate per liter H_(2) relative to alkaline seawater electrolysis with 37%lower energy equivalent input. | Lili Guo Qingping Yu Xuejun Zhai Jingqi Chi Tong Cui Yu Zhang Jianping Lai Lei Wang | 2022 | Nano Research2022，15，10： | 2 |
| 3 | Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat显示文摘 | Yuan Xue Nanchang Xie Lili Cao Xiuhe Zhao Hong Jiang Zhaofu Chi | 2011 | Neuroscience Letters2011，，2： | 1 |
| 4 | An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoY-2 variants显示文摘The wide transmission and host adaptation of SARS-CoV-2 have led to the rapid accumulation of mutations,posing significant challenges to the effectiveness of vaccines and therapeutic antibodies.Although several neutralizing antibodies were authorized for emergency clinical use,convalescent patients derived natural antibodies are vulnerable to SARS-CoV-2 Spike mutation. | Xiaojing Chi Xinhui Zhang Shengnan Pan Yanying Yu Yujin Shi Tianli Lin Huarui Duan Xiuying Liu Wenfang Chen Xuehua Yang Lan Chen Xiaoqian Dong Lili Ren Qiang Ding Jianwei Wang Wei Yang | 2022 | Signal Transduction and Targeted Therapy2022，7，3： | 1 |
| 5 | Reduction of fatty acid flux results in enhancement of astaxanthin synthesis in a mutant strain of Phaffia rhodozyma 显示文摘 | Miao Lili Wang Yongxing Chi Shuang etal | 2010 | Journal of Industrial Microbiology & Biotechnology2010，37，6： | 1 |
| 6 | An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19显示文摘The global spread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)requires an urgent need to find effective therapeutics for the treatment of coronavirus disease 2019(COVID-19).In this study,we developed an integrative drug repositioning framework,which fully takes advantage of machine learning and statistical analysis approaches to systematically integrate and mine large-scale knowledge graph,literature and transcriptome data to discover the potential drug candidates against SARS-CoV-2.Our in silico screening followed by wet-lab validation indicated that a poly-ADP-ribose polymerase 1(PARP1)inhibitor,CVL218,currently in Phase I clinical trial,may be repurposed to treat COVID-19.Our in vitro assays revealed that CVL218 can exhibit effective inhibitory activity against SARS-CoV-2 replication without obvious cytopathic effect.In addition,we showed that CVL218 can interact with the nucleocapsid(N)protein of SARS-CoV-2 and is able to suppress the LPS-induced production of several inflammatory cytokines that are highly relevant to the prevention of immunopathology induced by SARS-CoV-2 infection. | Yiyue Ge Tingzhong Tian Suling Huang Fangping Wan Jingxin Li Shuya Li Xiaoting Wang Hui Yang Lixiang Hong Nian Wu Enming Yuan Yunan Luo Lili Cheng Chengliang Hu Yipin Lei Hantao Shu Xiaolong Feng Ziyuan Jiang Yunfu Wu Ying Chi Xiling Guo Lunbiao Cui Liang Xiao Zeng Li Chunhao Yang Zehong Miao Ligong Chen Haitao Li Hainian Zeng Dan Zhao Fengcai Zhu Xiaokun Shen Jianyang Zeng | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 0 |
| 7 | Left-Symmetric Algebra Structures on the Planar Galilean Conformal Algebra显示文摘In this paper, we mainly determine the compatible left-symmetric algebra structures on the planar Galilean conformal algebra with some natural grading conditions. The results of earlier work on left-symmetric algebra structures on the twisted Heisenberg-Virasoro algebra play an important role in determining these compatible structures. As a corollary, any such left-symmetric algebra contains an infinite-dimensional non-trivial subalgebra that is also a submodule of the regular module. | Lili Chi Jiancai Sun | 2019 | Algebra Colloquium2019，26，2： | 0 |
| 8 | A photon-controlled diode with a new signal-processing behavior显示文摘The photodetector is a key component in optoelectronic integrated circuits.Although there are various device structures and mechanisms,the output current changes either from rectified to fully-on or from fully-off to fully-on after illumination.A device that changes the output current from fully-off to rectified should be possible.We report the first photon-controlled diode based on a n/n-molybdenum disulfide junction.Schottky junctions formed at the cathode and anode either prevent or allow the device to be rectifying,so that the output current of the device changes from fully-off to rectified.By increasing the thickness of the photogating layer,the behavior of the device changes from a photodetector to a multifunctional photomemory with the highest non-volatile responsivity of 4.8×10^(7)A/W and the longest retention time of 6.5×10^(6)s reported so far.Furthermore,a 3×3 photomemory array without selectors shows no crosstalk between adjacent devices and has optical signal-processing functions including wavelength and power-density selectivity. | Shun Feng Ruyue Han Lili Zhang Chi Liu Bo Li Honglei Zhu Qianbing Zhu Wei Chen Hui-Ming Cheng Dong-Ming Sun | 2022 | National Science Review2022，9，8： | 0 |
| 9 | Abnormal relationship between rust particles size and rust layer compactness of weathering steels显示文摘In order to reveal evolution of the rust layer during atmospheric corrosion,commercial weathering steel(WS) 09CuPCrNi and a recently developed bainite WS were subjected to a salt fog test.The protection and compactness of the rust layer were evaluated by electrochemical analysis,absorption-desorption test,etc.The experimental results indicate that more compact rust layer could be derived from the rust particles with larger size.The well-established notion that the rust particle growth can induce the decrement of corrosion resistance of WS.However,the present investigation shows that the notion might not be universally accurate.The unusual result means that the rust particles might grow anisotropically during corrosion. | Ming ZHANG Shanwu YANG Hua ZHENG Lili CHI Xinlai HE | 2010 | Acta Metallurgica Sinica(English Letters)2010，23，1： | 0 |
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