|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Brassinosteroid Enhances Jasmonate-Induced Anthocyanin Accumulation in Arabidopsis Seedlings显示文摘Jasmonate (JA) regulates plant development, mediates defense responses, and induces anthocyanin biosynthesis as well. Previously, we isolated the psc1 mutant that partially suppressed coi1 insensitivity to JA, and found that brassinosteroid (BR) was involved in JA signaling and negatively regulated JA inhibition of root growth in Arabidopsis. In this study it was shown that JA-induced anthocyanin accumulation was reduced in BR mutants or in wild type treated with brassinazole, an inhibitor of BR biosynthesis, whereas it was induced by an application of exogenous BR. It was also shown that the'late'anthocyanin biosynthesis genes including DFR, LDOX , and UF3GT, were induced slightly by JA in the BR mutants relative to wild type. Furthermore, the expression level of JA-induced Myb/bHLH transcription factors such as PAP1, PAP2, and GL3, which are components of the WD-repeat/Myb/bHLH transcriptional complexes that mediate the 'late' anthocyanin biosynthesis genes, was lower in the BR mutants than that in wild type. These results suggested that BR affects JA-induced anthocyanin accumulation by regulating the 'late' anthocyanin biosynthesis genes and this regulation might be mediated by the WD-repeat/Myb/bHLH transcriptional complexes. | Zhihong Peng Chengyun Han Libing Yuan Kun Zhang Hongman Huang Chunmei Ren | 2011 | Journal of Integrative Plant Biology2011，53，8： | 9 |
| 2 | A Scenario-Based Evaluation of COVID-19-Related Essential Clinical Resource Demands in China显示文摘The coronavirus disease 2019(COVID-19)pandemic is a global crisis,and medical systems in many countries are overwhelmed with supply shortages and increasing demands to treat patients due to the surge in cases and severe illnesses.This study aimed to assess COVID-19-related essential clinical resource demands in China,based on different scenarios involving COVID-19 spreads and interventions.We used a susceptible–exposed–infectious–hospitalized/isolated–removed(SEIHR)transmission dynamics model to estimate the number of COVID-19 infections and hospitalizations with corresponding essential healthcare resources needed.We found that,under strict non-pharmaceutical interventions(NPIs)or mass vaccination of the population,China would be able to contain community transmission and local outbreaks rapidly.However,under scenarios involving a low intensity of implemented NPIs and a small proportion of the population vaccinated,the use of a peacetime–wartime transition model would be needed for medical source stockpiles and preparations to ensure a normal functioning healthcare system.The implementation of COVID-19 vaccines and NPIs in different periods can influence the transmission of COVID-19 and subsequently affect the demand for clinical diagnosis and treatment.An increased proportion of asymptomatic infections in simulations will not reduce the demand for medical resources;however,attention must be paid to the increasing difficulty in containing COVID-19 transmission due to asymptomatic cases.This study provides evidence for emergency preparations and the adjustment of prevention and control strategies during the COVID-19 pandemic.It also provides guidance for essential healthcare investment and resource allocation. | Ting Zhang Qing Wang Zhiwei Leng Yuan Yang Jin Yang Fangyuan Chen Mengmeng Jia Xingxing Zhang Weiran Qi Yunshao Xu Siya Chen Peixi Dai Libing Ma Luzhao Feng Weizhong Yang | 2021 | Engineering2021，7，7： | 7 |
| 3 | Improved oxygen reduction reaction via a partially oxidized Co-CoO catalyst on N-doped carbon synthesized by a facile sand-bath method显示文摘High active and durable non-noble metal electrocatalysts are urgently developed to satisfy the high performance oxygen reduction reaction(ORR). We successfully synthesized Co-CoOx anchored on nitrogen-doped carbon via a facile sand-bath method(SBM), i.e., Co-CoOx/N-C(SBM). The as-obtained Co-CoOx/N-C(SBM) exhibited overwhelming superiorities to Co-CoO/N-C prepared by conventional heat treatment(CHT), particularly in electrochemical performance of ORR. Although Co-CoOx/N-C(SBM)showed smaller specific surface area of 276.8 m^2/g than that of 939.5 m^2/g from Co-CoO/N-C(CHT), the Co-CoOx/N-C(SBM) performed larger pore diameter and more Co_3O_4 active component resulting in better ORR performance in 0.1 mol/L KOH solution. The Co-CoO_x/N-C(SBM) delivered onset potential of 0.91 V vs. RHE, mid-wave potential of 0.85 V vs. RHE and limited current density of 5.46 mA/cm^2 much better than those of the Co-CoO/N-C(CHT). Furthermore, Co-CoOx/N-C(SBM) showed greater stability and better methanol tolerance superior to the commercial 20 wt% Pt/C. | Libing Hu Feng Yu Huifang Yuan Gang Wang Mincong Liu Lina Wang Xueyan Xue Banghua Peng Zhiqun Tian Bin Dai | 2019 | Chinese Chemical Letters2019，30，3： | 4 |
| 4 | Defective ZnS nanoparticles anchored in situ on N-doped carbon as a superior oxygen reduction reaction catalyst显示文摘Defect engineering has been used to develop low-cost and effective catalysts to boost oxygen reduction reactions.However,the development of catalysts that use metal cation vacancies as the active sites for oxygen reduction reaction is lacking.In this study,ZnS nanoparticles on N-doped carbon serve as an oxygen reduction reaction catalyst.These catalysts were prepared via a one-step method at 900℃.Amazingly,the high-resolution transmission electron microscope image revealed obvious defects in the ZnS nanoparticles.These facilitated the catalyst synthesis,and the product displayed good electrocatalytic performance for the oxygen reduction reaction in an alkaline medium,including a lower onset potential,lower mid-wave potential,four electron transfer process,and better durability compared with 20 wt%Pt/C.More importantly,the density functional theory results indicated that using the Zn vacancies in the prepared catalyst as active sites required a lower reaction energy to produce OOH*from*OO toward oxygen reduction reaction.Therefore,the proposed catalyst with Zn vacancies can be used as a potential electrocatalyst and may be substitutes for Pt-based catalysts in fuel cells,given the novel catalyst’s resulting performance. | Libing Hu Zengxi Wei Feng Yu Huifang Yuan Mincong Liu Gang Wang Bangfiua Peng Bin Dai Jianmin Ma | 2019 | Journal of Energy Chemistry2019，28，12： | 3 |
| 5 | Factors involved in the success of Castanea henryi stem cuttings in different cutting mediums and cutting selection periods显示文摘Chinquapin(Castanea henryi) is a dual-purpose tree species in China valued for as a source of timber and starch.We investigated the effect of four cutting mediums(pure vermiculite;peat:river sand at 3:1 v/v;peat:krasnozem at 1:1 v/v;and pure krasnozem) and three stem cutting periods(March,May,and July) on rooting performance of C.henryi cuttings.Different cutting periods and cutting mediums greatly influenced the rooting rate of C.henryi,ranging from 3.35 to 77.31%.Principal component analysis indicated that the best combination of cutting period and cutting medium was semi-hardwood cuttings(May cuttings)+krasnozem.Histological evidence indicated that adventitious root initials were present by week 5-6,and that the site of root primordia initiation was observed in the vascular cambium.Stem anatomical structures observed at different periods indicated that a xylem/radius ratio of29.90-37.42% and a fractured phloem fiber ring are indicative of rooting success.The relational model between rooting index and medium properties indicated that nutrient content and porosity significantly influenced callus production.However,pH strongly affected C.henryi root formation,with the Pearson correlation coefficients for May and July cuttings of-0.856 and-0.947,respectively.Our protocol is helpful to achieve mass clone propagation of improved C.henryi genotypes,thus overcoming a common hurdle in chinquapin breeding programs. | Wangzun Chen Libing He Shiyi Tian Joseph Masabni Huan Xiong Feng Zou Deyi Yuan | 2021 | Journal of Forestry Research2021，32，4： | 2 |
| 6 | Design of antibacterial peptide-like conjugated molecule with broad spectrum antimicrobial ability显示文摘Increasing multidrug-resistant(MDR) superbugs emerge worldwide causing a public health crisis. Consequently, it is urgent to find new antibiotics with efficient broad-spectrum antimicrobial activity. By virtue of versatility in molecular design, a new peptide-like cell membrane-broken molecule, oligo-(7,7′-bifluoren-benzo[c][1,2,5]thiadiazole)(OFBT) possessing a conjugated backbone and eight pendant guanidyl moieties was designed and synthesized. OFBT exhibits favorable broad-spectrum of antimicrobial activity to pathogens including Gram-negative and Gram-positive bacteria, and fungi with the minimum inhibitory concentration(MIC)below 3.0 μM. Moreover, OFBT exhibits high selectivity for pathogens over human cells to make it a promising broad spectrum antimicrobial agent. | Hui Chen Meng Li Zhang Liu Rong Hu Shengliang Li Yuan Guo Fengting Lv Libing Liu Yilin Wang Yuanping Yi Shu Wang | 2018 | Science China Chemistry2018，61，1： | 1 |
| 7 | Simultaneous and sensitive determination of multiplex chemical residues based on multicolor quantum dot probes显示文摘 | Chifang Peng Zhuokun Li Yinyue Zhu Wei Chen Yuan Yuan Liqiang Liu Qiusheng Li Dinghua Xu Ruirui Qiao Libing Wang Shuifang Zhu Zhengyu Jin Chuanlai Xu | 2009 | Biosensors and Bioelectronics2009，，12： | 1 |
| 8 | Effects of quantum dots in polymerase chain reaction 显示文摘 | WANG Libing ZHU Yingyue JIANG Yuan | 2009 | Journal of Physical Chemistry B2009，113，： | 1 |
| 9 | High efficient oxygen reduction performance of Fe/Fe3C nanoparticles in situ encapsulated in nitrogen-doped carbon via a novel microwave-assisted carbon bath method显示文摘Fe-based carbon materials are widely considered promising to replace Pt/C as next-generation electrocatalysts towards oxygen reduction reaction (ORR). However, the preparation of Fe-based carbon materials is still carried out by conventional heating method (CHM). Herein, a novel microwave-assisted carbon bath method (MW-CBM) was proposed, which only took 35 min to synthesize Fe/Fe3C nanoparticles encapsulated in N-doped carbon layers derived from Prussian blue (PB). The catalyst contained large specific surface area and mesoporous structure, abundant Fe-Nx and C–N active sites, unique core-shell structure. Due to the synergistic effects of these features, the as-prepared Fe/Fe3C@NC-2 displayed outstanding ORR activity with onset potential of 0.98 VRHE and halfwave potential of 0.87 VRHE, which were more positive than 20 wt.% Pt/C (0.93 VRHE and 0.82 VRHE). Besides, Fe/Fe3C@NC-2 gave a better stability and methanol tolerance than Pt/C towards ORR in alkaline media, too. | Mincong Liu Xue Yin Xuhong Guo Libing Hu Huifang Yuan Gang Wang Fu Wang Long Chen Lili Zhang Feng Yu | 2019 | Nano Materials Science2019，1，2： | 1 |
| 10 | Decreased influenza vaccination coverage among Chinese healthcare workers during the COVID-19 pandemic显示文摘Background:Healthcare workers(HCWs)were the priority group for influenza vaccination,in China during the 2020/2021 and 2021/2022 influenza seasons.However,vaccination rates in HCWs have always been low.This study investigated influenza vaccination status among Chinese HCWs and analyzed the factors driving vaccination.Methods:We provided electronic questionnaires to HCWs from January 27,2022 to February 21,2022,using the WeChat platform'Breath Circles'.HCWs who received the link could also forward it to their colleagues.Binary logistic regression models were used to analyze vaccination-associated factors among HCWs.Results:Among the 1697 HCWs surveyed,vaccination coverage was 43.7%(741/1697)during the 2020/2021 influenza season,and 35.4%(600/1697)during the 2021/2022 influenza season,as of February 21,2022.Additionally,22.7%(385/1697)and 22.1%(358/1697)of HCWs reported that their workplaces implemented a free vaccination policy for all employees during the 2020/2021 and 2021/2022 influenza seasons.HCWs who were required to be vaccinated according to hospital regulations,and whose hospitals implemented the free influenza vaccine policy were more likely to be vaccinated(2020/2021 and 2021/2022;P<0.05).In addition,the economic level of the HCWs'province(2021/2022,P<0.05)and the HCWs’knowledge about vaccination and willingness to get vaccinated,such as active learning about vaccines(2020/2021,P<0.05),supportive attitude toward vaccination for all HCWs(2020/2021 and 2021/2022;P<0.05),also had an impact on vaccine coverage.Conclusions:A free influenza vaccination policy and workplace required vaccination are effective in improving influenza vaccination coverage among HCWs.Influenza vaccination coverage of Chinese HCWs remained low and showed a downward trend after the COVID-19 outbreak.Further effective measures,such as advocacy campaigns,free vaccine policies,and on-site vaccination could be implemented to improve influenza vaccination coverage. | Libing Ma Xuan Han Yuan Ma Yuan Yang Yunshao Xu Di Liu Weizhong Yang Luzhao Feng | 2022 | Infectious Diseases of Poverty2022，11，5： | 1 |
| 11 | Recent developments in analytical applications of quantum dots显示文摘 | Hua Kuang Yuan Zhao Wei Ma Liguang Xu Libing Wang Chuanlai Xu | 2011 | Trends in Analytical Chemistry2011，，10： | 1 |
| 12 | miR-182 as a Prognostic Marker for Glioma Progression and Patient Survival显示文摘 | Lili Jiang Pu Mao Libing Song Jueheng Wu Jieting Huang Chuyong Lin Jie Yuan Lianghu Qu Shi-Yuan Cheng Jun Li | 2010 | The American Journal of Pathology2010，，： | 1 |
| 13 | Nucleic acids analysis显示文摘Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysis of nucleic acids and nucleic acids-based analysis have been widely applied in biological studies, clinical diagnosis, environmental analysis, food safety and forensic analysis.During the past decades, the field of nucleic acids analysis has been rapidly advancing with many technological breakthroughs.In this review, we focus on the methods developed for analyzing nucleic acids, nucleic acids-based analysis, device for nucleic acids analysis, and applications of nucleic acids analysis. The representative strategies for the development of new nucleic acids analysis in this field are summarized, and key advantages and possible limitations are discussed. Finally, a brief perspective on existing challenges and further research development is provided. | Yongxi Zhao Xiaolei Zuo Qian Li Feng Chen Yan-Ru Chen Jinqi Deng Da Han Changlong Hao Fujian Huang Yanyi Huang Guoliang Ke Hua Kuang Fan Li Jiang Li Min Li Na Li Zhenyu Lin Dingbin Liu Juewen Liu Libing Liu Xiaoguo Liu Chunhua Lu Fang Luo Xiuhai Mao Jiashu Sun Bo Tang Fei Wang Jianbin Wang Lihua Wang Shu Wang Lingling Wu Zai-Sheng Wu Fan Xia Chuanlai Xu Yang Yang Bi-Feng Yuan Quan Yuan Chao Zhang Zhi Zhu Chaoyong Yang Xiao-Bing Zhang Huanghao Yang Weihong Tan Chunhai Fan | 2021 | Science China Chemistry2021，64，2： | 1 |
| 14 | Antibacterial and antiparasitic activities analysis of a hepcidinlike antimicrobial peptide from Larimichthys crocea显示文摘As an economically important marine fish,the large yellow croaker Larimichthys crocea suffered from marine white spot disease caused by the ectoparasite Cryptocaryon irritans in recent years.This disease not only could result in physiological damage,but also lead to secondary bacterial invasion.Reports indicated some AMPs(antimicrobial peptides)were of antiparasitic activity to C.irritans.Hepcidin-like(Lc-HepL)was one of the significant differential expression genes excavated from the transcriptome following a challenge with C.irritans.In this study,we characterized this AMP’s bioactivity based on the levels of mRNA and protein.After challenged by C.irritans,qRT-PCR showed Lc-HepL was significantly upregulated in six tissues,including gill,muscle,liver,head kidney and spleen during theront infection,trophont falling off,and secondary bacterial invasion stages,which implicated a role Lc-HepL played in the immune defense against C.irritans and secondary bacterial infection.Recombinant Lc-HepL(rLc-HepL)was induced and purified successfully.rLc-HepL exhibited antibacterial activity to certain bacteria in a dose-and time-dependent manners.Anti-C.irritans activity was explored for the first time and found it could cause the theronts membrane rupture and contents leakage.These results provided the first evidence that Lc-HepL had strong antiparasitic activity against marine fish ectoparasites C.irritans theronts.Together,data indicated that Lc-HepL might be an important component in the innate immune system against C.irritans and has the potential to be employed in future drug development. | Libing Zheng Yuan Li Jun Wang Ying Pan Jia Chen Weiqiang Zheng Longshan Lin | 2020 | Acta Oceanologica Sinica2020，39，10： | 1 |
| 15 | A novel blue-purple Ce^(3+) doped whitlockite phosphor:Synthesis,crystal structure,and photoluminescence properties显示文摘At present,the rare earth(RE) ions doped phosphors have attracted more and more attention because of their excellent properties.In this paper,a series of novel blue-purple β-Ca_(3)(PO_(4))_(2):Ce^(3+) phosphors were synthesized by a high temperature solid phase method.The X-ray diffraction(XRD),infrared spectrum,energy dispersive spectroscopy(EDS),scanning electron microscopy(SEM),X-ray photoelectron spectroscopy(XPS),photoluminescence excitation and emission spectra were used to investigate the crystal structure,composition and the luminescent properties of the resulting samples.The phosphor shows a strong absorption in the ultraviolet band.Under the excitation of 269 nm,the phosphor emits a strong purple fluorescence ranging from 360 to 520 nm.When Ce^(3+) doping content is 0.07 mol,the strongest luminescence intensity is reached,and the concentration quenching mechanism is dipole-dipole(d-d)interaction for Ce^(3+) based on Dexter theory. | Yuli Yuan Haoran Lin Jing'ao Cao Qingfeng Guo Fei Xu Libing Liao Lefu Mei | 2021 | Journal of Rare Earths2021，39，6： | 1 |
| 16 | A universal hydrochloric acid-assistant powder-to-powder strategy for quick and mass preparation of lead-free perovskite microcrystals显示文摘Lead-free halide perovskite materials possess low toxicity,broadband luminescence and robust stability compared with conventional lead-based perovskites,thus holding great promise for eyes-friendly white light LEDs.However,the traditionally used preparation methods with a long period and limited product yield have curtailed the commercialization of these materials.Here we introduce a universal hydrochloric acid-assistant powder-to-powder strategy which can accomplish the goals of thermal-,pressure-free,eco-friendliness,short time,low cost and high product yield,simultaneously.The obtained Cs_(2)Na_(0.9)Ag_(0.1)In_(0.95)Bi_(0.05)Cl_(6)microcrystals exhibit bright self-trapped excitons emission with quantum yield of(98.3±3.8)%,which could retain(90.5±1.3)%and(96.8±0.8)%after continuous heating or ultraviolet-irradiation for 1000 h,respectively.The phosphor converted-LED exhibited near-unity conversion efficiency from ultraviolet chip to self-trapped excitons emission at~200 mA.Various ions doping(such as Cs_(2)Na_(0.9)Ag_(0.1)InCl_(6):Ln^(3+))and other derived lead-free perovskite materials(such as Cs_(2)ZrCl_(6)and Cs_(4)MnBi_(2)Cl_(12))with high luminous performance are all realized by our proposed strategy,which has shown excellent availability towards commercialization. | Huanxin Yang Xiangxiang Chen Yiyue Chu Changjiu Sun Haolin Lu Mingjian Yuan Yuhai Zhang Guankui Long Libing Zhang Xiyan Li | 2023 | Light(Science & Applications)2023，12，4： | 0 |
| 17 | Monte Carlo performance study of virtual high performance computing cluster over cloud显示文摘Objective:As a high computation cost discipline,nuclear science and engineering still relies heavily on traditional high performance computing(HPC)clusters.However,the usage of traditional HPC for nuclear science and engineering has been limited due to the poor flexibility,the software compatibility and the poor user interfaces.Virtualized/virtual HPC(vHPC)can mimic an HPC by using a cloud computing platform.In this work,we designed and developed a vHPC system for employment in nuclear engineering.Methods:The system is tested using the computation of the numberπby Monte Carlo and an X-ray digital imaging system simulation.The performance of the vHPC system is compared with that of the traditional HPCs.Results:As the number of the simulated particles increases,the virtual cluster computing time grows propor-tionally.The time used for the simulation of the X-ray imaging was about 21.1 h over a 12 kernels virtual server.Experimental results show that the performance of virtual cluster computing and the actual physical machine is almost the same.Conclusions:From these tests,it is concluded that vHPC is a good alternative for employing in nuclear engineering.The proposed vHPC in this paper will make HPC flexible and easy to deploy. | Libing Zhu Ze Xi Peng Cong Gongyi Yu Yuan Liu Xincheng Xiang Wei Xu Xiangang Wang | 2022 | Radiation Medicine and Protection2022，3，3： | 0 |
| 18 | Identification of Germline Mutations in East‑Asian Young Never‑Smokers with Lung Adenocarcinoma by Whole‑Exome Sequencing显示文摘Recently,an increasing number of young never-smokers are diagnosed with lung cancer.The aim of this study is to investigate the genetic predisposition of lung cancer in these patients and discover candidate pathogenic variants for lung adenocarcinoma in young never-smokers.Peripheral blood was collected from 123 never-smoking east-Asian patients diagnosed with lung adenocarcinoma before the age of 40.Whole-exome sequencing(WES)was conducted on genomic DNA extracted from peripheral blood cells.As a result,3,481 single nucleotide variants were identified.By bioinformatical tools and the published gene list associated with genetic predisposition of cancer,pathogenic variants were detected in ten germline genes:ATR,FANCD2,FANCE,GATA2,HFE,MSH2,PDGFRA,PMS2,SDHB,and WAS.Patients with pathogenic variants were more likely to occur in females(9/10,90.0%)and have stage IV lung adenocarcinoma(4/10,40%).Furthermore,germline muta-tions in 17 genes(ASB18,B3GALT5,CLEC4F,COL6A6,CYP4B1,C6orf132,EXO1,GATA4,HCK,KCP,NPHP4,PIGX,PPIL2,PPP1R3G,RRBP1,SALL4,and TTC28),which occurred in at least two patients,displayed potentially pathogenic effects.Gene ontology analysis further showed that these genes with germline mutations were mainly located in nucleo-plasm and associated with DNA repair-related biological processes.The study provides spectrum of pathogenic variants and functional explanation for genetic predisposition of lung adenocarcinoma in young never-smokers,which sheds a light on prevention and early diagnosis of lung cancer. | Fangqiu Fu Xiaoting Tao Zhonglin Jiang Zhendong Gao Yue Zhao Yuan Li Hong Hu Libing Shen Yihua Sun Yang Zhang | 2023 | Phenomics2023，3，2： | 0 |
| 19 | Willingness of Caregivers to Have Their Children Vaccinated with Pneumococcal Vaccines in the Context of an Innovative Immunization Strategy—Weifang City,Shandong Province,2021显示文摘Summary What is already known about this topic?Pneumococcal diseases(PDs)pose a serious health threat to children.Vaccination is the most costeffective intervention to prevent PDs,but pneumococcal vaccines coverage among children is low in China.What is added by this report?This study investigated the willingness of children’s caregivers to have their children vaccinated with pneumococcal vaccines under an innovative policy to offer 1-dose of the 13-valent pneumococcal conjugate vaccines at no charge to families.The research found that 70.51%of caregivers were willing to have their infants receive pneumococcal vaccines and that reducing the cost of vaccines may increase caregivers’willingness.What are the implications for public health practice?This is the first evaluation in China of acceptance of pneumococcal vaccines among children under a 1-dose,cost-free policy.The results provide scientific evidence for updating local and national pneumococcal immunization strategies to promote the use of the pneumococcal vaccine. | Yuan Yang Ting Zhang Yan Wang Libing Ma Shuyun Xie Jian Zhou Weiran Qi Qing Wang Peixi Dai Yuanze Du Luzhao Feng Chunping Wang Weizhong Yang | 2022 | China CDC weekly2022，4，20： | 0 |
| 20 | Electrochemical Regulation of Antibacterial Activity Using Ferrocene-Containing Antibiotics显示文摘The widespread use of antibiotics causes the accumulation of a large amount of antibiotics in the environment.Excessively active antibiotics in the environment results in the emergence of bacterial resistance.Building smart antibiotics capable of reversible regulation between active and inactive states on demand is a promising approach to address this issue.Herein,a ferrocene-containing quaternary ammonium compound has been developed for electrochemical redox-controlled bacterial inhibition.The reversible switch of the reduced and oxidized ferrocene groups between hydrophobic and hydrophilic states triggers the assembly and disassembly of the micelles while modulating the interactions of antibiotic molecules with the bacteria membrane,providing a new way to regulate antibacterial activity.In addition,the alternate use of reduced and oxidized antibiotics exhibits a favorable effect in preventing bacterial resistance.Thus,an unconventional strategy is offered to prevent the build-up of active bactericide in the environment and decrease bacterial resistance. | Song Shen Yiming Huang Anran Yuan Fengting Lv Libing Liu Shu Wang | 2021 | CCS Chemistry2021，3，11： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员