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| 1 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 2 | Efficacy and safety of Yinchenwuling powder for hyperlipidemia: a systematic review and Meta-analysis显示文摘OBJECTIVE:To assess the clinical effectiveness and adverse effects of Yinchenwuling powder(YCWLP)in the treatment of hyperlipidemia using Meta-analysis.METHODS:Seven electronic databases were searched for randomized controlled trials designed to evaluate the clinical effectiveness of YCWLP for hyperlipidemia published in any language prior to February 2015.Two reviewers independently identified articles,extracted data,assessed quality,and cross-checked the results.Revman 5.3 was used to analyze the data.RESULTS:Only five randomized controlled trials with poor methodology were included in the analy-sis.The five trials compared YCWLP with conventional lipid-lowering drugs.Meta-analysis indicated that YCWLP was more effective at the levels of total cholesterol and triglycerides,while increasing the level of high-density lipoprotein cholesterol without serious adverse effects.However,it was not more effective than lipid-lowering drugs in reducing low-density lipoprotein cholesterol and improving hemorheology.CONCLUSION:YCWLP appeared to improve lipid levels.However,given the high risk of bias among the trials,we could not conclude that YCWLP was beneficial to patients with hyperlipidemia.More rigorous trials are required to provide stronger evidence for the conclusion. | Yao Haiqiang Zhang Zengliang Wang Ji Zuo Jiacheng Chen Yu Zhu Libing Li Xiaoke Yang Zheng Wang Zisong Sun Ranran Xu Xuanxuan Li Changming Wu Yanling Li Lingru Wang Qi | 2016 | Journal of Traditional Chinese Medicine2016，36，2： | 11 |
| 3 | A Scenario-Based Evaluation of COVID-19-Related Essential Clinical Resource Demands in China显示文摘The coronavirus disease 2019(COVID-19)pandemic is a global crisis,and medical systems in many countries are overwhelmed with supply shortages and increasing demands to treat patients due to the surge in cases and severe illnesses.This study aimed to assess COVID-19-related essential clinical resource demands in China,based on different scenarios involving COVID-19 spreads and interventions.We used a susceptible–exposed–infectious–hospitalized/isolated–removed(SEIHR)transmission dynamics model to estimate the number of COVID-19 infections and hospitalizations with corresponding essential healthcare resources needed.We found that,under strict non-pharmaceutical interventions(NPIs)or mass vaccination of the population,China would be able to contain community transmission and local outbreaks rapidly.However,under scenarios involving a low intensity of implemented NPIs and a small proportion of the population vaccinated,the use of a peacetime–wartime transition model would be needed for medical source stockpiles and preparations to ensure a normal functioning healthcare system.The implementation of COVID-19 vaccines and NPIs in different periods can influence the transmission of COVID-19 and subsequently affect the demand for clinical diagnosis and treatment.An increased proportion of asymptomatic infections in simulations will not reduce the demand for medical resources;however,attention must be paid to the increasing difficulty in containing COVID-19 transmission due to asymptomatic cases.This study provides evidence for emergency preparations and the adjustment of prevention and control strategies during the COVID-19 pandemic.It also provides guidance for essential healthcare investment and resource allocation. | Ting Zhang Qing Wang Zhiwei Leng Yuan Yang Jin Yang Fangyuan Chen Mengmeng Jia Xingxing Zhang Weiran Qi Yunshao Xu Siya Chen Peixi Dai Libing Ma Luzhao Feng Weizhong Yang | 2021 | Engineering2021，7，7： | 7 |
| 4 | Petrogenesis of Paleoproterozoic Luyashan charnockitic rocks in Shanxi Province: Constraints from Geochemistry and Nd isotope显示文摘Luyashan charnockite pluton 主要由二长岩, adamellite , charnockite 和 syenogranite 组成,它被 TiO 2, P 2 O 5, K 2 O , Zr , Nb , Y , Pb , La , Ce , Ba 和更高的 K 2 O/Na 2 MgO , CaO , Mg #, Th , U 和更低的 Sr 的 O 和弄空 Ba 和 Rb Ba 。在 Zr, Nb, Ce 和 SiO 2 之间的否定关联从我类型花岗石是不同的。同位素地 Luyashan charnockite plutons 在 Nd 同位素是相对一致的,显示起始的 εNd(t)( 到 -6.97) 和 Nd 的 -5.93 弄空披风模型年龄(到 2.78 Ga 的 2.67 Ga ) 。这些特征显示那 Luyashan charnockitic 岩浆从先存在导出晚太古代的外壳的来源并且与公司 2-rich 液体的在特别高的温度下面的可能的 mafic granulites 的部分融化。石榴石在部分融化期间是一个主要剩余阶段。原来的干燥 charnockitic 岩浆在早结晶化期间经历了辉石,斜长石,磷灰石,和钛铁矿的水晶分别。geochemical 证据建议 Luyashan charnockitic 岩浆可能在碰撞以后的热松驰被产生并且高举在主要碰撞以后的构造背景(∼
1850 妈) 在东方、西方的大陆人块之间。 | LIU Chaohui LIU Shuwen LI Qiugen WANG Yueran DANG Qingning GU Libing YANG Bin ZHAO Fengsan | 2006 | Progress in Natural Science:Materials International2006，16，2： | 3 |
| 5 | Efficient purification of Al_(30) by organic complexation method显示文摘A method was developed for preparing high purity Al30O8(OH)56(H2O)_(24)^(18)+(Al30) through elimination of impurities by complexation.Polyaluminum chloride II(PAC_(30))with Al_(c )content of 75%was adopted as the source of Al_(30).The PAC_(30)was prepared under conditions of total aluminum concentration 0.1 mol/L and OH^-/Al ratio 2.2 to obtain the highest content of Al_(30).A precipitation/metathesis method,organic solvent precipitation method and organic complexation method were examined to separate and purify Al_(30).It was found that only by the organic complexation method could high purity Al_(30)products be obtained in large yield economically.In the experiments,benzoic acid was used as the coordinating reagent to decompose the main impurity AlO_4Al_(12)(OH)_(24)(H_2O)_(12)^(7+)(Al_(13)),and the Al_(30)product could be obtained by precipitation and metathesis operations.It was noteworthy that the decomposition of impurities by benzoic acid could be completed in 2 hr.The Al_(30)product was characterized by Ferron assay,^(27)Al-NMR,SEM,XRD and TGA.The results showed that the purity of the Al_(30)product could exceed 92%. | Libing Liu Qinxue Yang Pin Wang Feng Xiao Ruyuan Jiao Guangyu An Dongsheng Wang | 2019 | Journal of Environmental Sciences2019，31，6： | 2 |
| 6 | Synergistic effect enhances the peroxidase-like activity in platinum nanoparticle-supported metal—organic framework hybrid nanozymes for ultrasensitive detection of glucose显示文摘The metal—organic frameworks(MOFs)are expected as ideal biomimetic enzymes for colorimetric glucose detection because of their large surface areas,well defined pore structures,tunable chemical composition,and multi-functional sites.However,the intrinsically chemical instability and low mimetic enzyme activity of MOFs hinder the application of them in imitating the enzyme reactions.In this work,we demonstrated a metal-MOF synergistic catalysis strategy,by loading Pt nanoparticles(Pt NPs)on MIL-88B-NH2(Fe-MOF)to increase peroxidase-like activity for the detection of glucose.The induced electrons transfer from Pt atom to Fe atom accelerated the redox cycling of Fe^(3+)/Fe^(2+),improved the overall efficiency of the peroxidase-like reaction,and enabled the efficient and robust colorimetric glucose detection,which was proved by both experiments and density functional theory(DFT)calculation.Additionally,the sensitivity and chemical stability of this synergistic effect strategy to detect the glucose are not affected by the complex external factors,which represented a great potential in fast,easy,sensitive,and specific recognition of clinical diabetes. | Jing Li Jie Zhao Shengqiang Li Yang Chen Weiqiang Lv Jiahui Zhang Libing Zhang Zhen Zhang Xiaoquan Lu | 2021 | Nano Research2021，14，12： | 2 |
| 7 | Transcriptome and physiological analyses provide insights into the leaf epicuticular wax accumulation mechanism in yellowhorn显示文摘Plantations and production of yellowhorn,one of the most important woody oil and urban greening trees widely cultivated in northern China,have gradually become limited by drought stress.The epicuticular wax layer plays a key role in the protection of yellowhorn trees from drought and other stresses.However,there is no research on the mechanism of wax loading in yellowhorn trees.In this study,we investigated the anatomical and physiological characteristics of leaves from different germplasm resources and different parts of the same tree and compared their cuticle properties.In addition,the different expression patterns of genes involved in wax accumulation were analyzed,and a coexpression network was built based on transcriptome sequencing data.Morphological and physiological comparisons found that the sun leaves from the outer part of the crown had thicker epicuticular wax,which altered the permeability and improved the drought resistance of leaves,than did shade leaves.Based on transcriptome data,a total of 3008 and 1324 differentially expressed genes(DEGs)were identified between the sun leaves and shade leaves in glossy-and non-glossy-type germplasm resources,respectively.We identified 138 DEGs involved in wax biosynthesis and transport,including structural genes(such as LACS8,ECH1,and ns-LTP)and transcription factors(such as MYB,WRKY,and bHLH transcription factor family proteins).The coexpression network showed a strong correlation between these DEGs.The differences in gene expression patterns between G-and NG-type germplasm resources under different light conditions were very clear.These results not only provide a theoretical basis for screening and developing drought-resistant yellowhorn germplasm resources but also provide a data platform to reveal the wax accumulation process of yellowhorn leaves. | Yang Zhao Xiaojuan Liu Mengke Wang Quanxin Bi Yifan Cui Libing Wang | 2021 | Horticulture Research2021，8，1： | 2 |
| 8 | Overwhelming electrochemical oxygen reduction reaction of zinc-nitrogen-carbon from biomass resource chitosan via a facile carbon bath method显示文摘Developing high efficiency and low cost electrocatalysts is critical for the enhancement of oxygen reduction reaction(ORR),which is the fundamental for the development and commercialization of renewable energy conversion technology.Herein,zinc-nitrogen-carbon(Zn-N-C)was prepared by using biomass resource chitosan via a facile carbon bath method.The obtained Zn-N-C delivered a high specific surface area(794.7 cm^2/g)together with pore volume(0.49 cm^3/g).During the electrochemical evaluation of oxygen reduction reaction(ORR),Zn-N-C displayed high activity for ORR with an onset pote ntial E0=0.96 VRHE and a half wave potential E1/2=0.86 VRHE,which were more positive than those of the comme rcial 20 wt%Pt/C benchmark catalyst(E0=0.96 VRHE and E1/2=0.81 VRHE).In addition,the ZnN-C catalyst also had a better stability and methanol tolerance than those of the Pt/C catalyst. | Libing Hu Feng Yu Fu Wang Shengchao Yang Banghua Peng Long Chen Gang Wang Juan Hou Bin Dai Zhi-Qun Tian | 2020 | Chinese Chemical Letters2020，31，5： | 2 |
| 9 | Treatment of domestic wastewater by using a microaerobic membrane bioreactor显示文摘 | Libing Chu Xingwen Zhang Fenglin Yang | 2006 | Desalination2006，189，： | 1 |
| 10 | Influence of design parameters on end effect in long primary doub- le-sided linear induction motor 显示文摘 | YANG Tong ZHOU Libing LI Langru | 2011 | IEEE Transactions on Plasma Science2011，39，1： | 1 |
| 11 | Anaerobic treatment of domestic wastewater in a membrane-coupled expended granular sludge bed (EGSB) reactor under moderate to low temperature显示文摘 | CHU Libing YANG Fenglin ZHANG Xinwen | 2005 | Process Biochemistry2005，40，： | 1 |
| 12 | RT instability in cylindrical implosion of jelly ring显示文摘 | Yang Libing Liao Haidong Sun Chenwei | 2004 | Chin Phys2004，13，10： | 1 |
| 13 | Preparation and Composition-structure-thermal Stability Relation of a Novel Open-framework Vanadium Phosphate (H3NCH2CH2NH3)3显示文摘 | Yang Zanzhong Liao Libing Du Hongbing | 2002 | Journal of University of Science and Technology Beijing (Mineral Metallurgy Materials)2002，9，1： | 1 |
| 14 | Influence of design parameters on end effect in long primary double-sided linear induction motor显示文摘 | Yang Tong Zhou Libing Li Langru | 2010 | IEEE Transactions on Plasma Science2010，39，1： | 1 |
| 15 | Influ- ence of design parameters on end effect in long primary double-sided linear induction motor显示文摘 | YANG Tong ZHOU Libing LI Langru | 2011 | IEEE Transactions on Plasma Science2011，39，1： | 1 |
| 16 | Anaerobic treatment of domestic wastewater in a membrane-coupled expended granular sludge bed (EGSB) reactor under moderate to low temperature显示文摘 | LIBING CHU FENGLIN YANG XINGWEN ZHANG | 2005 | Process Biochemistry2005，40，34： | 1 |
| 17 | Slr0151 in Synechocystis sp. PCC 6803 is required for efficient repair of photosystem Ⅱ under high-light condition显示文摘Cyanobacteria are ancient photosynthetic prokareyotes that have adapted successfully to adverse environments including high-light irradiation. Although it is known that the repair of photodamaged photosystem Ⅱ(PSⅡ) in the organisms is a highly regulated process, our knowledge of the molecular components that regulate each step of the process is limited.We have previously identified a hypothetical protein Slr0151 in the membrane fractions of cyanobacterium Synechocystis sp.PCC 6803. Here, we report that Slr0151 is involved in PSⅡ repair of the organism. We generated a mutant strain(Dslr0151)lacking the protein Slr0151 and analyzed its characteristics under normal and high-light conditions. Targeted deletion of slr0151 resulted in decreased PSⅡ activity in Synechocystis. Moreover,the mutant exhibited increased photoinhibition due to impairment of PSⅡ repair under high-light condition. Further analysis using in vivo radioactive labeling and 2-D blue native/sodium dodecylsulfate polyacrylamide gel electrophoresis indicated that the PSⅡ repair cycle was hindered at the levels of D1 synthesis and disassembly and/or assembly of PSⅡ in the mutant. Protein interaction assays demonstrated that Slr0151 interacts with D1 and CP43 proteins. Taken together,these results indicate that Slr0151 plays an important role in regulating PSⅡ repair in the organism under high-light stress condition. | Haomeng Yang Libing Liao Tingting Bo Lei Zhao Xuwu Sun Xuefeng Lu Birgitta Norling Fang Huang | 2014 | Journal of Integrative Plant Biology2014，56，12： | 1 |
| 18 | Study on the pipe friction resistance in long-distance rock pipe jacking engineering显示文摘Previous studies on pipe friction resistance are mainly concentrated in the soil layer,whereas the study on that in the rock stratum is limited.To estimate the pipe friction resistance in the rock stratum,the calculation models of pipe friction resistance and their applica-tion conditions were compared first.Then the friction resistance calculation model for pipe jacking in the rock stratum was established and simplified.Lastly,the measured(FM)and the computed(FN)pipe friction resistance was compared to validate the simplified friction resistance calculation model.The following conclusions can be drawn:(1)The existing calculation methods of pipe friction resistance can be well verified in the soil layer but cannot be applied in the rock stratum.(2)Sediment,pipe–rock friction coefficient and mud buoyancy are the main factors affecting the pipe friction resistance in long-distance rock pipe jacking engineering.(3)The simplified calculation model established by Deng et al.can estimate the pipe friction resistance in different rock strata at different jacking stages with satisfac-tory outcomes.Further research on the pipe-rock friction coefficient in different rock strata with different pipe–rock contact conditions merits further investigation to better predict the pipe friction resistance in the rock stratum.The research results have certain practica-bility and can provide a reference for similar projects. | Peng Chen Xinrong Liu Zhiyun Deng Ninghui Liang Libing Du Han Du Yedi Huang Lingyun Deng Gaoyang Yang | 2023 | Underground Space2023，，2： | 1 |
| 19 | Anaerobic treatment of domestic wastewater in a membrane-coupled expended granular sludge bed (EGSB) reactor under moderate to low temperature显示文摘 | Libing Chu Fenglin Yang Xingwen Zhang | 2005 | Process Biochemistry2005，40，34： | 1 |
| 20 | Multiplex detection of KRAS and BRAF mutations using cationic conjugated polymers显示文摘The mutation detections of KRAS and BRAF genes are of significant importance to predict the responses to anti-cancer therapy and develop new drugs. In this paper, we developed a multi-step fluorescence resonance energy transfer (FRET) assay for multiplex detection of KRAS and BRAF mutations using cationic conjugated polymers (CCP). The newly established detection system could detect as low as 2% mutant DNAs in DNA admixtures. By triggering the emission intensity change of CCP and the dyes labeled in the DNA, four possible statuses (three mutations and one wildtype) can be differentiated in one extension reaction. The detection efficiency of this new method in clinical molecular diagnosis was validated by determining KRAS and BRAF mutations of 51 formalin-fixed paraffin-embedded (FFPE) ovary tissue samples. Furthermore, the result of the CCP-based multi-step FRET assay can be directly visualized under UV light so that no expensive instruments and technical expertise are needed. Thus, the assay provides a sensitive, reliable, cost-effective and simple method for the detection of disease-related gene mutations. | XING BaoLing SONG JinZhao GE SuMei TANG ZhengHua LIU MengLu YANG Qiong Lü FengTing LIU LiBing WANG Shu | 2013 | Chinese Science Bulletin2013，58，8： | 1 |
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