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68篇 您的检索式:作者名="Li Defa"
    题名 作者 年代 出处 被引量
1Cavitation characteristics of pit structure in ultrasonic field显示文摘Bubble collecting, bubble holding and micro-bubble ejecting characteristics of pit structure and the influence of cavitation bubble on the development of erosion pit are investigated by means of highspeed photography experiments. Pits tend to collect and hold wandering cavitation bubbles. The air holding phenomenon of pits can be a destination of the incubation period in the process of cavitation erosion. The holding bubble tends to eject micro-bubbles from the top of holding cavitation bubble, making the pit a source of nuclei. With bubbles being held in pits, the diameters of pits increase rapidly. But in the given experiment condition, there is a specific stable value beyond which the diameter of pits will not increase. This characteristic will be helpful in understanding and predicting the cavitation erosion process.BAI LiXin XU WeiLin ZHANG FaXing LI NaiWen ZHANG YiChi HUANG DeFa 2009Science China(Technological Sciences)2009,52,7:11
2The effects of dietary fiber level on nutrient digestibility in growing pigs显示文摘The objective of this study was to investigate the effects of total dietary fiber level on nutrient digestibility and the relationship between apparent total tract digestibility of total dietary fiber, and soluble dietary fiber, insoluble dietary fiber and available energy. Sugar beet pulp was as the only fiber source. The experiment was designed as a 6×6 Latin square with an adaptation period of 7 d followed by a 5-d total collection of feces and urine. Feed intake tended to decrease(P=0.10) as total dietary fiber level increased. The apparent total tract digestibility of dry matter, crude protein and gross energy decreased(P<0.01) when total dietary fiber increased but the digestibility of soluble dietary fiber and insoluble dietary fiber increased(P<0.01). The digestible energy and metabolizable energy content of diets decreased(P<0.01) as the total dietary fiber increased.Wenjuan Zhang Defa Li Ling Liu Jianjun Zang Qiwu Duan Wenjun Yang Liying Zhang 2013Journal of Animal Science and Biotechnology2013,4,4:9
3Net energy of corn,soybean meal and rapeseed meal in growing pigs显示文摘Background: Two experiments were conducted to estimate the net energy(NE) of corn, soybean meal, expel er-pressed rapeseed meal(EP-RSM) and solvent-extracted rapeseed meal(SE-RSM) using indirect calorimetry and to validate the NE of these four ingredients using pig growth performance.Methods: In Exp.1, 24 barrows(initial BW = 36.4 ± 1.6 kg) were allotted to 1 of 4 diets which included a corn basal diet,a corn-soybean meal basal diet and two rapeseed meal diets containing 20% EP-RSM(9.5% ether extract) or SE-RSM(1.1% ether extract) substituted for corn and soybean meal. The design allowed the calculation of NE values of corn,soybean meal and rapeseed meals according to the difference method. In Exp.2, 175 growing pigs(initial BW = 36.0± 5.2 kg) were fed 1 of 5 diets for 28 d, with five pigs per pen and seven replications(pens) per treatment in order to validate the measured energy values. Diets were a corn-soybean meal diet and four diets including 10% or 20% EP-RSM and 10% or 20% SE-RSM.Results: The NE of corn, soybean meal, EP-RSM and SE-RSM were 12.46, 11.34, 11.71 and 8.83 MJ/kg DM, respectively. The NE to ME ratio of corn(78%) was similar to tabular values, however, the NE to ME ratios of soybean meal(70%) and rapeseed meal(76%) were greater than tabular values. The greater NE value in EP-RSM than in SE-RSM is consistent with its higher EE content. Increasing EP-RSM or SE-RSM did not affect the growth performance of pigs and the caloric efficiency of NE was comparable for al diets.Conclusions: The NE of EP-RSM was similar to soybean meal, and both were greater than SE-RSM. The DE, ME and NE values measured in Exp.1 are confirmed by results of Exp. 2 with comparable caloric efficiencies of DE, ME or NE for all diets.Zhongchao Li Yakui Li Zhiqian Lv Hu Liu Jinbiao Zhao Jean Noblet Fenglai Wang Changhua Lai Defa Li 2017Journal of Animal Science and Biotechnology2017,8,4:7
4Methodologies on estimating the energy requirements for maintenance and determining the net energy contents of feed ingredients in swine:a review of recent work显示文摘In the past two decades, a considerable amount of research has focused on the determination of the digestible(DE) and metabolizable energy(ME) contents of feed ingredients fed to swine. Compared with the DE and ME systems, the net energy(NE) system is assumed to be the most accurate estimate of the energy actually available to the animal. However, published data pertaining to the measured NE content of ingredients fed to growing pigs are limited. Therefore, the Feed Data Group at the Ministry of Agricultural Feed Industry Centre(MAFIC) located at China Agricultural University has evaluated the NE content of many ingredients using indirect calorimetry. The present review summarizes the NE research works conducted at MAFIC and compares these results with those from other research groups on methodological aspect. These research projects mainly focus on estimating the energy requirements for maintenance and its impact on the determination, prediction, and validation of the NE content of several ingredients fed to swine. The estimation of maintenance energy is affected by methodology, growth stage,and previous feeding level. The fasting heat production method and the curvilinear regression method were used in MAFIC to estimate the NE requirement for maintenance. The NE contents of different feedstuffs were determined using indirect calorimetry through standard experimental procedure in MAFIC. Previously generated NE equations can also be used to predict NE in situations where calorimeters are not available. Although popular, the caloric efficiency is not a generally accepted method to validate the energy content of individual feedstuffs. In the future,more accurate and dynamic NE prediction equations aiming at specific ingredients should be established, and more practical validation approaches need to be developed.Zhongchao Li Hu Liu akui Li Zhiqian Lv Ling Liu Changhua Lai Junjun Wang Fenglai Wang Defa Li Shuai Zhang 2018Journal of Animal Science and Biotechnology2018,9,3:6
5Metabolic characteristics and nutrient utilization in high-feedefficiency pigs selected using different feed conversion ratio models显示文摘An understanding of the nutrient utilization characteristics of pigs with different feed efficiencies(FEs) will help us to develop new strategies to reduce the costs of pig production.In this study,we selected pigs with a range of FEs according to two feed conversion ratio models: the feed intake(FI) model,where pigs had the same average daily gains(ADGs) but different FIs,and the ADG model,where pigs had the same FIs but different ADGs.High-FE pigs had a higher abundance of short chain fatty acid(SCFA)-producing bacteria(Lachnospiraceae,Clostridiaceae1,and Coriobacteriaceae) in their caecum in the FI model,and low-FE pigs had a higher abundance of two families(BacteroidalesS247group and Peptococcaceae) and two genera(Anaerotruncus and CandidatusSoleaferrea) in both models.By contrast,high-FE pigs had more goblet cells and higher m RNA expression of insulin-like growth factor 1(IGF-1) in the FI model,and higher mRNA expression of occludin but lower expressions of adenosine monophosphate-activated protein kinase(AMPK)-α2 and peroxisome proliferator-activated receptor gamma coactivator 1 alpha(PGC1α) in the ADG model.These findings suggest that the presence of SCFA-producing bacteria in the caecum and increased muscular growth may contribute to the high FE of low-FI pigs,while improved intestinal functions and decreased mitochondrial activity in the skeletal muscle are related to the high FE of high-ADG pigs.Beibei He Tiantian Li Wei Wang Hang Gao Yu Bai Shuai Zhang Jianjun Zang Defa Li Junjun Wang 2019Science China(Life Sciences)2019,62,7:5
6Effect of variety and drying method on the nutritive value of corn for growing pigs显示文摘Background:This experiment was conducted to determine the nutritive value of corn from the north of China for growing pigs.The experiment examined corn variety(LS1,LS2,LS3 and LS4)grown in one location,drying method(sun dried and artificially dried)and different drying temperatures.Corn harvested at 20-25%moisture was dried to about 12%moisture by sun drying and artificially drying at 80,100,or 120℃ in a fluidized bed dryer.Ninety-six barrows(average BW of 33.4 ± 2.7 kg)were housed in individual metabolism crates to facilitate separate collection of feces and urine.A five-day collection period followed a seven-day diet acclimation period.Results:The results indicated that variety significantly influenced(P<0.01)the 1,000 kernel weight of corn but not the bulk weight.Variety also influenced the available energy content(digestible energy of dry matter,P<0.01;metabolisable energy of dry matter,P<0.01)and digestibility of organic matter(P<0.01),as well as dry matter(P<0.01)and gross energy(GE)content(P<0.02).The drying method of corn significantly influenced the 1,000 kernel weight(P<0.01),bulk weight(P<0.01)and digestibility of ether extract(EE)(P<0.01).No effect of drying temperature on the digestibility of organic matter,dry matter(DM),crude protein(CP),neutral detergent fiber(NDF),acid detergent fiber(ADF)and gross energy was observed,but gelatinization(P<0.05)and test weight(P<0.01)decreased with an increase in temperature.Conclusions:Variety has a significant impact on the nutritive value of corn for growing pigs,and greater attention needs to be paid to these influences in the assignment of the nutritive value of corn given to growing pigs.Quanfeng Li Meng Shi Chuanxin Shi Dewen Liu Xiangshu Piao Defa Li Changhua Lai 2014Journal of Animal Science and Biotechnology2014,5,4:5
7Use of near-infrared reflectance spectroscopy for the rapid determination of the digestible energy and metabolizable energy content of corn fed to growing pigs显示文摘Background: The ability of near-infrared reflectance spectroscopy(NIRS) to determine the digestible energy(DE)and metabolizable energy(ME) content of corn fed to growing pigs was tested. One hundred and seventeen corn samples, comprising different planting regions and varieties were collected from all over China in a three-year period. The samples were randomly split into a calibration set(n = 88) and a validation set(n = 29). The actual and calculated DE and ME content of the corn samples was determined by digestion-metabolism experiments and the prediction equations of Noblet and Perez(J Anim Sci. 71:3389–98,1993). The samples were then subjected to NIRS scanning and calibrations were performed by the modified partial least square(MPLS) regression method based on77 different spectral pre-treatments. The NIRS equations based on the actually determined and calculated DE and ME were built separately and then validated using validation samples.Results: The NIRS equations obtained from actually determined DE, the coefficient of determination for calibration(RSQ_(cal)), cross-validation(R^2_(CV)), and validation(RSQ_v) were 0.89, 0.87 and 0.86, and these values for determined ME were 0.87, 0.86 and 0.86. For the NIRS equations built from calculated DE, the RSQ_(cal), R^2_(CV), and RSQvvalues were 0.88, 0.85 and 0.84, and these values for calculated ME were 0.86, 0.84 and 0.82. Except for the equation based on calculated ME(RPD_v= 2.38, < 2.50), the other three equations built from actually determined energy and calculated DE produced good prediction performance(RPD_vranging from 2.53 to 2.69, > 2.50) when applied to validation samples.Conclusion: These results indicate that NIRS can be used as a quantitative method for the rapid determination of the available energy in corn fed to growing pigs, and the NIRS equations based on the actually determined energy produced better predictive performance than those built from calculated energy values.Juntao Li Quanfeng Li Defa Li Yiqiang Chen Xiaoxiao Wang Wenjun Yang Liying Zhang 2017Journal of Animal Science and Biotechnology2017,8,1:4
8Autophagy and the nutritional signaling pathway显示文摘During their growth and development, animals adapt to tremendous changes in order to survive. These include responses to both environmental and physiological changes and autophagy is one of most important adaptive and regulatory mechanisms. Autophagy is defined as an autolytic process to clear damaged cellular organelles and recycle the nutrients via lysosomic degradation. The process of autophagy responds to special conditions such as nutrient withdrawal. Once autophagy is induced,phagophores form and then elongate and curve to form autophagosomes. Autophagosomes then engulf cargo,fuse with endosomes, and finally fuse with lysosomes for maturation. During the initiation process, the ATG1/ULK1(unc-51-like kinase 1) and VPS34(which encodes a class III phosphatidylinositol(Ptd Ins) 3-kinase) complexes are critical in recruitment and assembly of other complexes required for autophagy. The process of autophagy is regulated by autophagy related genes(ATGs). Amino acid and energy starvation mediate autophagy by activating m TORC1(mammalian target of rapamycin) and AMPactivated protein kinase(AMPK). AMPK is the energy status sensor, the core nutrient signaling component and the metabolic kinase of cells. This review mainly focuses on the mechanism of autophagy regulated by nutrient signaling especially for the two important complexes,ULK1 and VPS34.Long HE Shabnam ESLAMFAM Xi MA Defa LI 2016Frontiers of Agricultural Science and Engineering2016,3,3:4
9A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2显示文摘The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying asymptomatic and presymptomatic carriers of the virus,and thus highlights a strong motivation for diagnostics with high sensitivity that can be rapidly deployed.On the other hand,several concerning SARS-CoV-2 variants,including Omicron,are required to be identified as soon as the samples are identified as‘positive’.Unfortunately,a traditional PCR test does not allow their specific identification.Herein,for the first time,we have developed MOPCS(Methodologies of Photonic CRISPR Sensing),which combines an optical sensing technology-surface plasmon resonance(SPR)with the‘gene scissors’clustered regularly interspaced short palindromic repeat(CRISPR)technique to achieve both high sensitivity and specificity when it comes to measurement of viral variants.MOPCS is a low-cost,CRISPR/Cas12a-systemempowered SPR gene-detecting platform that can analyze viral RNA,without the need for amplification,within 38 min from sample input to results output,and achieve a limit of detection of 15 fM.MOPCS achieves a highly sensitive analysis of SARS-CoV-2,and mutations appear in variants B.1.617.2(Delta),B.1.1.529(Omicron)and BA.1(a subtype of Omicron).This platform was also used to analyze some recently collected patient samples from a local outbreak in China,identified by the Centers for Disease Control and Prevention.This innovative CRISPR-empowered SPR platform will further contribute to the fast,sensitive and accurate detection of target nucleic acid sequences with single-base mutations.Zhi Chen Jingfeng Li Tianzhong Li Taojian Fan Changle Meng Chaozhou Li Jianlong Kang Luxiao Chai Yabin Hao Yuxuan Tang Omar AAl-Hartomy Swelm Wageh Abdullah GAl-Sehemi Zhiguang Luo Jiangtian Yu Yonghong Shao Defa Li Shuai Feng William J.Liu Yaqing He Xiaopeng Ma Zhongjian Xie Han Zhang 2022National Science Review2022,9,8:3
10The effect of the ratio of standardized ileal digestible lysine to metabolizable energy on growth performance,blood metabolites and hormones of lactating sows显示文摘A total of 335 lactating sows (Landrace × Large White) were used in two experiments to determine the optimum ratio of standardized ileal digestible lysine (SID-Lys) to metabolizable energy (ME) for mixed parity sows during lactation. In Exp. 1, 185 sows (weighing an average of 256.2 ± 6.5 kg and having an average parity of 3.4 ± 0.3) were allocated to one of six experimental diets in a completely randomized block design within parity groups (1, 2, and 3+). The experimental diets were formulated to contain 3.06, 3.16, 3.20, 3.25, 3.30 or 3.40 Mcal/kg of ME and each diet was fed to the sows throughout a 28 day lactation. All diets provided a similar SID-lysine level (0.86%). As a result, the diets provided a SID-Lys:ME ratio of 2.81, 2.72, 2.69, 2.65, 2.61 or 2.53 g/Mcal ME. Sow feed intake was significantly (P < 0.01) affected by the energy content of the diet as well as by sow parity. Using regression analysis, feed intake was shown to be maximized at 3.25, 3.21, 3.21 and 3.21 Mcal/kg of ME for parity 1, 2, 3+ sows and the entire cohort of sows respectively (quadratic; P < 0.01). In addition, the result of feed intake can be expressed as 2.65, 2.69, 2.69 and 2.68 g/Mcal based on analysis of SID-Lys:ME ratio. Litter weight gain was affected by dietary treatment for parity 3+ sows and the entire cohort (P < 0.01). Based on regression analysis, litter weight gain was maximized at 3.25 and 3.24 Mcal/kg of ME for parity 3+ (quadratic; P < 0.01) and the entire cohort (quadratic; P < 0.01). Similarly, the result of litter weight gain could be expressed as 2.65 and 2.66 g/Mcal of SID- Lys:ME ratio. Therefore, 3.25 Mcal/kg of ME was selected for Exp. 2 in which 150 sows (weighing 254.6 ± 7.3 kg and having an average parity of 3.4 ± 0.4) were allocated to one of five treatments in a completely randomized block design within parity (1, 2, and 3+). The experimental diets were formulated to contain 2.1, 2.4, 2.7, 3.0 or 3.3 g/Mcal of SID-Lys:ME ratio with all diets providing 3.25 Mcal/kg of ME. The diets were fed to the sows throughout a 28 day lactation. Sow body weight loss was affected by dietary treatment (parity 3+ sows, P = 0.02; entire cohort, P < 0.01) and by sow parity (P < 0.01). Litter weight at weaning and litter weight gain were affected by dietary treatment for parity 1, 2, 3+ sows and the entire cohort (P < 0.01) as well as by sow parity (P < 0.01). Plasma urea nitrogen (P < 0.01), creatinine (P < 0.01) and non-esterifide fatty acids (P = 0.04) were decreased as the SID-Lys:ME ratio of the diet increased. Insulin-like growth factor-1 (P = 0.02), estradiol (P < 0.01) and luteinizing hormone (P = 0.02) were increased as the SID-Lys:ME ratio in diet increased. Based on a broken-line model, the estimated SID-Lys: ME ratio to maximize litter weight gain was estimated to be 3.05 g/Mcal.Lingfeng Xue Xiangshu Piao Defa Li Pengfei Li Rongfei Zhang Sung Woo Kim Bing Dong 2012Journal of Animal Science and Biotechnology2012,3,3:3
11Preparation Porous Monolithic Column and Its Chromatographic Performance显示文摘结合连续加料降低聚合体系的放热量,及强化体系的换热能力等措施,实现了无搅拌模式聚合体系中温度分布的均一化.通过单次聚合过程构造了体积为38 mL的大体积整体固定相.SEM及孔隙率分布测试证明了整体固定相具有均匀的孔结构,动态容量测定及分离蛋白质的实验,表明所制备的径向流动模式整体柱的容量及分辨率不依赖于流速,同时在高流速下具有低背压的特征,可用于生物大分子的分离制备.Chen Guoliang Zhang Xiaohui Shang Defa Wang Qingbin Yang Changlong Li Tong 2006分析化学2006,34,10:3
12Lipids and membrane-associated proteins in autophagy显示文摘Autophagy is essential for the maintenance of cellular homeostasis and its dysfunction has been linked to various diseases.Autophagy is a membrane driven process and tightly regulated by membrane-associated proteins.Here,we summarized membrane lipid composition,and membrane-associated proteins relevant to autophagy from a spatiotemporal perspective.In particular,we focused on three important membrane remodeling processes in autophagy,lipid transfer for phagophore elongation,membrane scission for phago-phore closure,and autophagosome-lysosome membrane fusion.We discussed the significance of the discoveries in this field and possible avenues to follow for future studies.Finally,we summarized the membrane-associated biochemical techniques and assays used to study membrane properties,with a discussion of their applications in autophagy.Linsen Li Mindan Tong Yuhui Fu Fang Chen Shen Zhang Hanmo Chen Xi Ma Defa Li Xiaoxia Liu Qing Zhong 2021Protein & Cell2021,12,7:3
13Predicting corn digestible and metabolizable energy content from its chemical composition in growing pigs显示文摘Background:The nutrient composition of corn is variable.To prevent unforeseen reductions in growth performance,grading and analytical methods are used to minimize nutrient variability between calculated and analyzed values.This experiment was carried out to define the sources of variation in the energy content of com and to develop a practical method to accurately estimate the digestible energy(DE) and metabolisable energy(ME)content of individual com samples for growing pigs.Twenty samples were taken from each of five provinces in China(Jilin,Hebei,Shandong,Liaoning,and Henan) to obtain a range of quality.Results:The DE and ME contents of the 100 corn samples were measured in 35.3 ± 1.92 kg growing pigs(six pigs per corn sample).Sixty corn samples were used to build the prediction model;the remaining forty samples were used to test the suitability of these models.The chemical composition of each corn sample was determined,and the results were used to establish prediction equations for DE or ME content from chemical characteristics.The mean DE and ME content of the 100 samples were 4,053 and 3,923 kcal/kg(dry matter basis),respectively.The physical characteristics were determined,as well,and the results indicated that the bulk weight and 1,000-kernel weight were not associated with energy content.The DE and ME values could be accurately predicted from chemical characteristics.The best fit equations were as follows:DE,kcal/kg of DM = 1062.68 +(49.72 x EE) +(0.54 x GE) +(9.11 x starch),with R^2 = 0.62,residual standard deviation(RSD) = 48 kcal/kg,and P< 0.01;ME,kcal/kg of dry matter basis(DM) = 671.54 +(0.89 x DE)-(5.57 x NDF)-(191.39 x ash),with R2 = 0.87,RSD = 18 kcal/kg,and P<0,01.Conclusion:This experiment confirms the large variation in the energy content of corn,describes the factors that influence this variation,and presents equations based on chemical measurements that may be used to predict the DE and ME content of individual corn samples.Quanfeng Li Jianjun Zang Dewen Liu Xiangshu Piao Chanqhua Lai Defa Li 2014Journal of Animal Science and Biotechnology2014,5,3:2
14A simple fingerprinting scheme for large user groups显示文摘数字采指纹是一种新兴的技术保护多媒体数据免受海盗行为的伤害,在每个分布式的拷贝用唯一的鉴定信息被标记的地方。在采指纹编码,反串通代码的每 codeword 被用来代表一条用户指纹。在真实世界的应用程序,潜在的用户的数字能很大,因此,使用的 anticollusion 代码应该是容易的构造并且有尽可能多的 codewords。这份报纸建议一个简单编码采指纹的计划,在 anticollusion 代码与一个身份矩阵被构造的地方。我们的计划的主要优点是它的简洁,当很多指纹能容易被产生提供很多用户。改进串通抵抗,一些转变在嵌入的阶段在原来的指纹上被执行,相应反的转变在察觉阶段在提取顺序上被执行。Defa HU Qiaoliang LI 2011Frontiers of Computer Science2011,5,2:2
15PORK PRODUCTION SYSTEMS IN CHINA:A REVIEW OF THEIR DEVELOPMENT,CHALLENGES AND PROSPECTS IN GREEN PRODUCTION显示文摘This paper reviews the changes in pork production in China,the largest pork producing and consuming nation in the world.The pork sector in China has changed dramatically since the 1990s,with large-scale intensive pork production systems replacing the former,exclusively family-based pork production systems.Modern breeding,feeding,vaccinating,and management technologies are widely used now.However,smallholders still account for a large proportion of the total production.The intensification and specialization of the pork sector is expected to continue in the future,but there is increasing awareness and pressure to develop more environmentally-sustainable production systems.The relative shortage of domestically produced feed,the low utilization efficiency of feed ingredients,the large emissions of nitrogen and phosphorus to the environment,the high use of antibiotics,and the presence of residual metals in manures are very large challenges for the pork sector nowadays.To solve these problems,techniques including new feed resource utilization,precise feeding,low-protein diets,alternatives to antibiotics and increased manure recycling are all important topics and research directions today.With new techniques and management approaches,it is possible to build more sustainable pork production systems in China.Shuai ZHANG Xin WU Dandan HAN Yong HOU Jianzhuang TAN Sung Woo KIM Defa LI Yulong YIN Junjun WANG 2021Frontiers of Agricultural Science and Engineering2021,8,1:2
16Development of amonoclonal antibody-based competitive ELISA for detection of β-conglycinin,an allergen from soybean显示文摘YOU Jinming LI Defa QIAO Shiyan 0,,:1
17Transient hypersensitivityto soybean meal in the early weaned pig显示文摘LI Defa NELSSEN J L REDDY P G 1990Journal of Animal Science1990,68,:1
18Effects of replacing maize with Chinese brown rice on growth performance and apparent fecal digestibility of nutrients in weanling pigs显示文摘Li Defa Zhang D F Piao X S 2002Asian-Australian J of Ani Sci2002,15,8:1
19Central GLP-2 Enhances Hepatic Insulin Sensitivity via Activating PI3K Signaling in POMC Neurons显示文摘Xuemei Shi Fuguo Zhou Xiaojie Li Benny Chang Depei Li Yi Wang Qingchun Tong Yong Xu Makoto Fukuda Jean J. Zhao Defa Li Douglas G. Burrin Lawrence Chan Xinfu Guan 2013Cell Metabolism2013,,1:1
20Development of a monoclonal antibody-based competitive ELISA for detection of β-conglycinin,an allergen from soybean显示文摘YOU Jinming LI Defa QIAO Shiyan 2008Food Chem2008,106,:1
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