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| 1 | VHL and HIF-1α: gene variations and prognosis in early-stage clear cell renal cell carcinoma显示文摘 | Francesca Lessi Chiara Maria Mazzanti Sara Tomei Claudio Cristofano Andrea Minervini Michele Menicagli Alessandro Apollo Lorenzo Masieri Paola Collecchi Riccardo Minervini Marco Carini Generoso Bevilacqua | 2014 | Medical Oncology2014，，3： | 2 |
| 2 | Titanium-coated polypropylene mesh as innovative bioactive material in conservatives mastectomies and pre-pectoral breast reconstruction显示文摘Breast reconstruction is rapidly evolving,thanks to the growing acceptance of synthetic meshes as innovative biomaterials.276 patients undergoing mastectomy(total of 328 mastectomies)were analyzed in a retrospective observational study to evaluate the pre-pectoral immediate breast reconstruction(IBR)using an implant wrapped with Titanium-Coated Polypropylene Mesh(TCPM)vs.patients treated with tissue expander(TE),equally placed pre-pectorally(and wrapped with the same TCPM in 74.3%of the control group’breasts).163 patients,of the study group(SG),underwent mastectomy and pre-pectoral IBR with implant wrapped with TCPM,in a one-step surgery,called direct-to-implant technique(DTI),while 113 patients control group(CG)underwent mastectomy and TE.DTI technique has been performed in 192 breasts of the SG while TE procedure in 136 breasts of the CG.The BREAST-Q questionnaire has been provided before the treatment and 2 years later.Baker scale has been used to evaluate capsular contracture.Oncologic,surgical,and aesthetic outcomes along with BREAST-Q scores were analyzed.Additionally,a histologic evaluation was conducted in 11 capsules’samples randomly chosen(6 derived from SG patients and 5 derived from CG).Complications were recorded in 43 cases(29SG-14CG):8 skin-nipple necrosis(5SG-3CG),8 wound dehiscence(6SG-2CG),3 hematomas(1SG-2CG),and 24 infections(8SG-16CG).Grade IV capsular contracture was detected in 9 breasts(1SG-8CG),whereas 254 breasts were grade I(110SG-144CG),33(10SG-23CG)grade II,and 32(4SG-28CG)grade III.Implant wrinkling was detected in 18 cases(10SG-8CG)after 30 months.The local tumor recurrence rate was 5.8%.Three recurrences were on the nipple-areola complex(1.9%).SG patients showed significantly higher rates in the BREAST-Q overall Satisfaction with Outcome(74.1),overall Satisfaction with Breasts(69.1),Psychosocial Well-being(81.9),and Sexual Well-being(63.1),versus CG’s patients(p<0.05).Histological analysis showed a process of normal tissue repair with a complete mesh integration and normal healing.Conservative mastectomies with pre-pectoral IBR assisted by TCPM proved themselves oncologically safe,biologically integrated into native tissues,and highly accepted in terms of quality of life guaranteeing a more natural and aesthetic breast appearance.Core tip:This retrospective observational study provided clinical and histological outcomes of the pre-pectoral IBR using an implant wrapped with TCPM vs.patients treated with TE,equally placed pre-pectorally.The efficacy of IBR using an implant wrapped with TCPM was confirmed by the cosmetic results obtained and by a rate of side effects comparable to TE.All the histological analyses performed confirmed the TCPM mesh complete integration with the physiological aspects of healing:The Collagen 1 and 3 expressions did not differ,between TCPM and NO TCPM samples to confirm a process of healing overlapping to perfect device incorporation and normal healing. | Pietro Gentile Marco Bernini Lorenzo Orzalesi Silvia Sordi Icro Meattini Francesca Lessi Ashutosh Kothari Claudio Calabrese | 2021 | Bioactive Materials2021，6，12： | 2 |
| 3 | Dispersion of ventricular repolarization and arrhythmic cardiac death in coronary disease 显示文摘 | Zareba LV Moss AI Lessies | 1994 | Am J Cardiol1994，74，6： | 1 |
| 4 | Implantation defects in infertile woman with endometriosis显示文摘 | Lessy BA | 2002 | Ann N Y Acad Sci2002，955，5： | 1 |
| 5 | Ischemic stroke as clinical onset of POEMS syndrome显示文摘 | Dacci P Lessi F Dalla Bella E | 2013 | J Neurol2013，260，12： | 1 |
| 6 | Disruption of cy- clin D1 nuclear export and proteolysis accelerates mamma- ry carcinogenesis 显示文摘 | Lin DI Lessie MD Gladden AB | 2008 | Oncogene2008，27，9： | 1 |
| 7 | Sorption and pre- concentration of metal ions on silica gel modified with 2, 5-dimercapto-1,3,4-thiadiazole 显示文摘 | Pedro Lessi Newton L Dias Filho | 1996 | Analytiea Chimica Acta1996，327，： | 1 |
| 8 | Tenascin is differently expressed in endometrium and endometriosis显示文摘 | Harrington D J Lessy B A Rai V | 1999 | J Pathol1999，187，12： | 1 |
| 9 | Dispersion of ventricular repolariation and arrhythmic cardiac death in coronary artery disease显示文摘 | Zereba W Moss A I Lessie S | 1994 | Am J Cardiol1994，74，： | 1 |
| 10 | Strangulated obturator hernia:a report of 17 cases显示文摘 | Hennekinne MS Pessaux P Du-P lessis R | | 0，，03： | 1 |
| 11 | Implantation defects in infertile woman with endometriosis显示文摘 | Lessy B A | 2002 | Ann N Y Acad Sci2002，955，： | 1 |
| 12 | VHL and HIF-1α:gene variations and prognosis in early-stage clear cell renal cell carcinoma显示文摘 | Lessi F Mazzanti CM Tomei S | 2014 | Med Oncol2014，31，3： | 1 |
| 13 | Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species显示文摘 | De Milito A lessi E Logozzi M Lozupone F Spada M Marino M L | 2007 | Cancer Res2007，67，： | 1 |
| 14 | Dispersion of ventricular repolarization and arrhythmic cardiac death in coronary artery disease显示文摘 | Zareba W Moss A I Lessie S | 1994 | Am J Cardiol1994，74，： | 1 |
| 15 | Muscle atro- phy and functional deficits of knee extensors and flexors in people with chronic stroke 显示文摘 | Prado-Medeiros CL Silva MP Lessi GC | 2012 | Phys Ther2012，92，3： | 1 |
| 16 | A morpho-molecular diagnosis ofpapiUary thyroid carcinoma: BRAF V600E detection as an important tool in preoperative evaluation of fine-needle aspirates 显示文摘 | Marchetti I Lessi F Mazzanti CM | 2009 | Thyroid2009，19，8： | 1 |
| 17 | Muscle atrophy and functional deficits of knee extensors and flexors in people with chronic stroke 显示文摘 | Prado-Medeiros CL Silva MP Lessi GC | 2012 | Phys Ther2012，92，3： | 1 |
| 18 | Dispersion of ventricular repolarization and arrhythmic cardiac death in coronary artery disease显示文摘 | Moss AJ Lessie S | 1994 | Am J Cardiol1994，74，55： | 1 |
| 19 | Time perspective and smoking,obesity,and exercise in a community sample显示文摘 | GUTHRIE LC LESSI K OCHI O | 2013 | Am J Health Behav2013，37，2： | 1 |
| 20 | Purification and characterization of the two 6-phosphogluconate dehydrogenase species from Pseudomonas multivorans显示文摘 | Lee Y N Lessie T G | | 0，，03： | 1 |
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