|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | GSTM1,GSTT1,GSTP1 and CYP1A1 genetic polymorphisms and susceptibility to esophageal cancer in a French population:Different pattern of squamous cell carcinoma and adenocarcinoma显示文摘AIM: To evaluate the association between CYPIA1 and GSTs genetic polymorphisms and susceptibility to esophageal squamous cell carcinoma (SCC) and esophageal adenocarcinorna (ADC) in a high risk area of northwest of France.METHODS: A case-control study was conducted to investigate the genetic polymorphisms of these enzymes (CYPIAI*2C and GSTP1 exon 7 Val alleles, GSTM1 *2/*2 and GSl-l-l*2/*2 null genotypes). A total of 79 esophagealcancer cases and 130 controls were recruited. RESULTS: GSTM2*2/*2 and CYP1A1*1A/*2C genotype frequencies were higher among squamous cell cardnomas at a level close to statistical significance (OR = 1.83, 95% CI0.88-3.83, P= 0.11; OR = 3.03, 95% CI 0.93-9.90, P= 0.07,respectively). For GSTP1 polymorphism, no difference wasfound between controls and cases, whatever their histological status. Lower frequency of GST/-1 deletion was observed in ADC group compared to controls with a statistically significant difference (OR=13.31, 95% CI 1.66-106.92, P<0.01).CONCLUSION: In SCC, our results are consistent with the strong association of this kind of turnout with tobacco exposure. In ADC, our results suggest 3 distinct hypotheses:(1) activation of exogenous procarcinogens, such as small halogenated compounds by GSTTI', (2) contribution of GSTT1 to the inflammatory response of esophageal mucosa, which is known to be a strong risk factor for ADC,possibly through leukotriene synthesis; (3) higher sensitivity to the inflammatory process associated with intracellular depletion of glutathione. | Ahmed Abbas Karine Delvinquière Mathilde Lechevrel Pierre Lebailly Pascal Gauduchon Guy Launoy Fran ois Sichel | 2004 | World Journal of Gastroenterology2004，10，23： | 7 |
| 2 | Hiccup in adults:an overview显示文摘 | Bizec JL Whitelaw WA | 1993 | Eur Respir J1993，6，： | 1 |
| 3 | Le syndrome du compariment abdominal显示文摘 | Pottecher T Segura P Launoy A | 2001 | Ann Chir2001，126，3： | 1 |
| 4 | Who Benefits from Portal Vein Resection during Pancreaticoduodenectomy for Pancreatic Cancer?显示文摘 | Bernard Launois Christian Stasik Eustathios Bardaxoglou Bernard Meunier Jean Pierre Campion Luigi Greco Francis Sutherland | 1999 | World Journal of Surgery1999，，9： | 1 |
| 5 | Lesyndrome do compartment abdominal显示文摘 | Potteeher T Segura P Launoy A | 2001 | Ann Chir2001，126，3： | 1 |
| 6 | The Paths Toward IPv6 Multihoming显示文摘 | Launois C Bagnulo M | 2006 | IEEE Communication Surveys and Tutorials2006，8，2： | 1 |
| 7 | Estimating the cost-effectiveness of stroke units in France compared with conventional care 显示文摘 | Launois R Giroud M M6gnigb&o AC | 2004 | Stroke2004，35，3： | 1 |
| 8 | Unbiased estimates of long‐term net survival of solid cancers in France显示文摘 | Valérie Jooste Pascale Grosclaude Laurent Remontet Guy Launoy Isabelle Baldi Florence Molinié Patrick Arveux Nadine Bossard Anne‐Marie Bouvier Marc Colonna | 2013 | Cancer2013，，10： | 1 |
| 9 | Promlxal bible duct cancer high respectability rate and 5-years survival 显示文摘 | Launois B Terblanehe I Lakehal M | 1999 | Ann Surg1999，230，2： | 1 |
| 10 | Improvement of pulmonary hypertension after liver transplantation显示文摘 | Schott R Chaouat A Launoy A | 1999 | Chest1999，115，： | 1 |
| 11 | Cutaneous leish- maniasis: progress towards a vaccine 显示文摘 | Launois P Tacchini-Cottier F Kieny M P | 2008 | Expert Rev Vaccines2008，28，7： | 1 |
| 12 | Who benefits from portal vein resection during pancreatieoduodeneetomy for pancreatic cancer 显示文摘 | Launois B Stasik C Bardaxoglou E | 1999 | World J Surg1999，23，4： | 1 |
| 13 | Total pancreatectomy for ductal adenocarcinoma of the pancreas with special reference to resection of the portal vein and multicentric cancer显示文摘 | B. Launois M.D. F.A.C.S. J. Franci M.D. E. Bardaxoglou M.D. M. P. Ramee M.D. J. L. Paul M.D. Y. Malledant M.D. J. P. Campion M.D | 1993 | World Journal of Surgery1993，，1： | 1 |
| 14 | Construction and valida- tion of a quality of life questionnaire in chronic lower limb ve- nous insufficiency(CIVIQ)显示文摘 | Launois R Reboul-Marty J Henry B | 1996 | Qual Life Res1996，5，6： | 1 |
| 15 | Hiccup inadults:an overview显示文摘 | Launois S Bizec JL Whitelaw WA | 1993 | Eur Respir J1993，6，4： | 1 |
| 16 | Promixal bile duct can-cer high respectability rate and 5-year survival显示文摘 | Launois B Terblanche J Lakehal M | 1999 | Ann Surg1999，230，2： | 1 |
| 17 | Preoperative radiotherapy for carcinoma of the esophagus显示文摘 | Launois B Delarue D Campion TP | 1981 | Surg Gynecol Obstet1981，153，5： | 1 |
| 18 | Salvage esophagectomy after unsuccessful curative chemoradiotherapy for squamouseell cancer of the esophagus 显示文摘 | Meunier B Raoul J Le Prise E Lakehal M Launois B | 1998 | Dig Surg1998，15，： | 1 |
| 19 | Construction and validation of a quality of life questionnaire in chronic lower limb venous insufficiency显示文摘 | Launois R Reboul - Malty J Heary B | 1996 | Qual Life Res1996，5，6： | 1 |
| 20 | Surgery for hilar cholangiocarcinoma: French experience in a collective survey of 552 extrahepatic bile duct cancers 显示文摘 | LAUNOIS B REDING R LEBEAU G | 2000 | J Hepat Bil Panc Surg2000，7，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员