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| 1 | 水泥基复合材料浆体厚度分布的定量表达显示文摘依据统计物理学领域中的弦长密度函数,提出了水泥基复合材料邻近集料间浆体厚度分布的定量估计方法。借助计算机模拟方法生成的模型结构验证该理论方法的可靠性。通过浆体厚度的数量基概率密度曲线和累计概率曲线的比较发现,理论解和模拟结果之间能较好吻合。在常用集料体积分数下,用该解析解预测了集料符合Fuller分布的砂浆和混凝土中浆体厚度分布及其平均值随集料体积分数和集料细度的变化关系。结果发现:邻近集料间浆体厚度平均值的变化范围为190~860μm。 | 陈惠苏 孙伟 SLUYS Lambertus Johannes STORVEN Piet | 2007 | 硅酸盐学报2007，35，12： | 5 |
| 2 | Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma显示文摘Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer(NSCLC)risk,biological mechanisms of these variants remain largely unknown.By integrating a large-scale genotype data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology-specific meta-analyses and functional annotations of both reported and novel susceptibility variants.We identified 3064 credible risk variants for NSCLC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hypersensitive sites.Transcription factor enrichment analysis revealed that USF1 was AD-specific while CREB1 was SqCC-specific.Functional annotation and genebased analysis implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(ER=1.95,P=0.005).Pathway enrichment analysis and Gene-Set Enrichment Analysis revealed that AD genes were primarily involved in immune-related pathways,while SqCC genes were homologous recombination deficiency related.Our results illustrate the molecular basis of both wellstudied and new susceptibility loci of NSCLC,providing not only novel insights into the genetic heterogeneity between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments. | Na Qin Yuancheng Li Cheng Wang Meng Zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen Lam Adonina Tardon Chu Chen Gary Goodman Stig EBojesen Maria Teresa Landi Mattias Johansson Angela Risch H-Erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay Shete Loic Le Marchand Olle Melander Hans Brunnstrom Geoffrey Liu Rayjean JHung Angeline Andrew Lambertus AKiemeney Shan Zienolddiny Kjell Grankvist Mikael Johansson Neil Caporaso Penella Woll Philip Lazarus Matthew BSchabath Melinda CAldrich Victoria LStevens Guangfu Jin David CChristiani Zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen | 2021 | Frontiers of Medicine2021，15，2： | 3 |
| 3 | 新拌水泥浆体中邻近胶凝材料粒子表面最近间距分布的解析解显示文摘依据Torquato的最邻近表面函数公式,推导了新拌水泥浆体邻近水泥粒子表面最近间距分布的解析解,并采用计算机模拟生成了1个水泥浆体结构模型,选取邻近粒子表面最近间距概率密度分布曲线、区间概率曲线和累计概率分布曲线这3个函数检验模拟结果与理论结果之间的差别。结果表明,该解析解与计算机模拟实验结果吻合良好。利用该解析解,以Rosin-Rammler分布为例,研究了胶凝材料细度以及水胶比对邻近水泥粒子表面最近间距分布及其平均值的影响。结果显示,水泥细度对邻近粒子表面最近间距平均值的影响高于水胶比的影响。邻近粒子表面最近间距解析解的获得,不但为基于不同粒径分布以及尺度范围粉体之间搭配的高粉体初始堆积密度的实现提供了依据,而且对多尺度模拟方法中选取各级模型的尺度、量化粉煤灰浆体中粉煤灰颗粒的微集料效应、了解邻近集料间的交互作用程度以及界面重叠程度等问题具有参考价值。 | 陈惠苏 孙伟 周焱昌 STROEVEN Piet SLUYS Lambertus Johannes | 2007 | 复合材料学报2007，24，1： | 2 |
| 4 | Operator Effort and the Measurement of Heart-Rate Variability显示文摘 | Jans Aasman Gijsbertus Mulder Lambertus J M Mulder | 1987 | Human Factors1987，29，2： | 2 |
| 5 | DD3 PCA3 -based Molecular Urine Analysis for the Diagnosis of Prostate Cancer显示文摘 | Daphne Hessels Jacqueline M.T. Klein Gunnewiek Inge van Oort Herbert F.M. Karthaus Geert J.L. van Leenders Bianca van Balken Lambertus A. Kiemeney J.Alfred Witjes Jack A. Schalken | 2003 | European Urology2003，，1： | 2 |
| 6 | Gender differences in the trend of colorectal cancer incidence in Singapore, 1968–2002显示文摘 | Inge M. C. M. Kok Chia Siong Wong Kee Seng Chia Xueling Sim Chuen Seng Tan Lambertus A. Kiemeney Helena M. Verkooijen | 2008 | International Journal of Colorectal Disease2008，，5： | 1 |
| 7 | Color Selection and Location Selection in ERPs:Differences,Similarities and ' Neural Specificity'显示文摘 | Jan J L Albertus A W Lambertus J M | 1998 | Biological Psychology1998，48，： | 1 |
| 8 | Nutrient dynamics in shallow lakes: effects of changes in loading and role of sediment-water interactions显示文摘 | Lambertus Lijklema | 1994 | Hydrobiologia1994，，1： | 1 |
| 9 | Development and eutrophication显示文摘 | Lambertus L | 1995 | Water Science and Technology1995，31，9： | 1 |
| 10 | Uhrafast gas chromatographic separation of organophosphor and organosulfur compounds utilizing a microcountercurrent flame photometric detector显示文摘 | KENDLER S REIDY S M LAMBERTUS G R | 2006 | Anal Chem2006，78，19： | 1 |
| 11 | Gender differences in stage-adjusted bladder cancer survival显示文摘 | N.Aydin Mungan Katja K.H Aben Mark P Schoenberg Otto Visser Jan-Willem W Coebergh J.Alfred Witjes Lambertus A.L.M Kiemeney | 2000 | Urology2000，，6： | 1 |
| 12 | Primary Production Estimation from Continuous Oxygen Measurements in Relation to External Nutrient Input显示文摘 | Robert P Kees K Lambertus L | 1996 | Water Research1996，30，3： | 1 |
| 13 | Regulation of hepcidin:Insights from biochemical analyses on human serum samples显示文摘 | Erwin HJM Kemna-April ER Lambertus JH | 2008 | Blood Cell Mol Dis2008，40，3： | 1 |
| 14 | Phosphorus accumulation in sediments and internal loading 显示文摘 | Lambertus I | 1986 | Hydrobiology Bulletin1986，20，1： | 1 |
| 15 | Bifidobacterium carbohydrases-their role in breakdown and synthesis of ( potential) prebiotics显示文摘 | LAMBERTUS A M van den BROEK SANDRA W A | 2008 | Mol Nutr Food Res2008，52，1： | 1 |
| 16 | Synthesis of all four homochiral stereoisomers of methyl 3-phenyl-1H-aziridine-2-carboxylate显示文摘 | Jos Porskamp J M Adriaan A W M van Loon etc | 1990 | Tetrahedron1990，46，7： | 1 |
| 17 | Evolution of the Ablation Region After Magnetic Resonance–Guided High-Intensity Focused Ultrasound Ablation in a Vx2 Tumor Model显示文摘 | Joost W. Wijlemans Roel Deckers Maurice A.A.J. van den Bosch Beatrijs A. Seinstra Marijn van Stralen Paul J. van Diest Chrit T.W. Moonen Lambertus W. Bartels | 2013 | Investigative Radiology2013，，： | 1 |
| 18 | Development and eutrophication显示文摘 | Lambertus L | 1995 | Water Science and Technology1995，31，9： | 1 |
| 19 | DD3 PCA3 -based Molecular Urine Analysis for the Diagnosis of Prostate Cancer显示文摘 | Daphne Hessels Jacqueline M.T. Klein Gunnewiek Inge van Oort Herbert F.M. Karthaus Geert J.L. van Leenders Bianca van Balken Lambertus A. Kiemeney J.Alfred Witjes Jack A. Schalken | 2003 | European Urology2003，，1： | 1 |
| 20 | Trends in polymer electrolytes for secondary lithium batteries显示文摘 | Felix B D Lambertus P Jakobert B J V | 2000 | J Power Sources2000，88，2： | 1 |
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