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| 1 | Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: Responders versus nonresponders显示文摘瞄准:探索直肠的氮的氧化物(没有) 作为处理的简历标记,在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ,并且检验在之间的关系直肠没有,没有 synthases (NOS ) 的粘膜表示,和支持 inflammatory cytokines。方法:有 UC 的 22 个病人并且 24 在类固醇治疗期间与 CD 被监视。直肠没有层次被测量,临床的活动在天被估计 1, 3, 7 和 28。NOS 和支持 inflammatory cytokines 的粘膜存在被免疫组织化学和 RT-PCR 分析。结果:显著地显示的活跃 UC 和 CD 增加了直肠没有层次(10950 +/- 1280 每十亿分开的 7610 和 5040 +/-(ppb ) ,分别地) 作为与控制相比(154 +/- 71 ppb, P <
0.001 ) 。直肠不在 UC 和 CD 与疾病活动微弱地相关(r = 0.34 为 UC 和 r = 0.48 为 CD, P <
0.01 ) 。在 12 个病人,一堂类固醇倔强的功课导致了结肠切除术。仅仅稍微有的这些病人没增加层次(UC:620 +/- 270 ppb;CD:1260 +/- 550 ppb ) 与那些相比与治疗学的回答(UC:18860 +/- 530 ppb, P <
0.001;CD:10060 +/- 3200 ppb, P <
0.05 ) 。结论:直肠没有水平是在是的 IBD 的治疗反应的一个有用简历标记低没有层次预言差的临床的回答到类固醇治疗。 | Tryggve Ljung Sofie Lundberg Mark Varsanyi Catharina Johansson Peter T Schmidt Max Herulf Jon O Lundberg Per M Hellstr(o|¨)m | 2006 | World Journal of Gastroenterology2006，12，21： | 10 |
| 2 | Influence of confining prestress on the transition from interface defeat topenetration in ceramic targets显示文摘Replica scaled impact experiments with unconfined ceramic targets have shown that the transition velocity,i.e.,the impact velocity at which interface defeat ceases and ceramic penetration occurs,decreased as the length scale increased.A possible explanation of how this scale effect is related to the formation of a cone crack in the ceramic has been presented by the authors in an earlier paper.Here,the influence of confinement and prestress on cone cracking and transition velocity is investigated.The hypothesis is that prestress will suppress the formation and growth of the cone crack by lowering the driving stress.A set of impact experiments has been performed in which the transition velocity for four different levels of prestress has been determined.The transition velocities as a function of the level of confining prestress is compared to an analytical model for the influence of prestress on the formation and extension of the cone crack in the ceramic material.Both experiments and model indicate that prestress has a strong influence on the transition from interface defeat to penetration,although the model underestimates the influence of prestress. | Patrik LUNDBERG RenéRENSTROM Olof ANDERSSON | 2016 | Defence Technology(防务技术)2016，12，3： | 4 |
| 3 | Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome显示文摘 | M. B. O. Lowén E. A. Mayer M. Sj?berg K. Tillisch B. Naliboff J. Labus P. Lundberg M. Str?m M. Engstr?m S. A. Walter | 2013 | Aliment Pharmacol Ther2013，，12： | 4 |
| 4 | 远洋系统中的持久性有机污染物(POPs)显示文摘有几项研究表明水生生物群中富营养化与持久性有机污染物(POPs)的吸收之间存在着相互作用。其主要概念是:由于营养物的过度排放,水生生态系统中生物量与生产增加,引起了一系列的变化,从而造成初级生产者(浮游植物)对POPs的吸收减少。其影响还会波及不同营养级的消费者。这一系列的变化可以间接地通过有机物沉淀的增加起作用,使污染物向底层的沉降流量增加,从而使污染物在底层被有机沉淀物所结合。这一系列的变化还会直接地起作用,作为'生长稀释'作用的后果,生长快速的浮游植物对POPs的吸收减少,使污染物在食物网中的转移减少。这种作用也可能是食物网结构改变的结果,而食物网结构的变化在寡营养型和富营养型的生态系统中极为不同。本文运用现有的有关不同营养状况的水生系统中POPs行为的知识,对波罗的海的富营养化与污染物之间的相互作用进行了讨论。波罗的海受到POPs的重度污染并正在富营养化是众所周知的。对湖泊进行调查的结果用于对实验室研究结果和在波罗的海的现场研究结果进行比较。 | Per Larsson Agneta Andersson Dag Broman Johan Nordbck Erik Lundberg 李应仁 | 2000 | AMBIO-人类环境杂志2000，29，4： | 3 |
| 5 | Intravenous immune globulin suppresses angiogenesis in mice and humans显示文摘Human intravenous immune globulin(IVIg),a purified IgG fraction composed of~60%IgG1 and obtained from the pooled plasma of thousands of donors,is clinically used for a wide range of diseases.The biological actions of IVIg are incompletely understood and have been attributed both to the polyclonal antibodies therein and also to their IgG(IgG)Fc regions.Recently,we demonstrated that multiple therapeutic human IgG1 antibodies suppress angiogenesis in a target-independent manner via FcγRI,a high-affinity receptor for IgG1.Here we show that IVIg possesses similar anti-angiogenic activity and inhibited blood vessel growth in five different mouse models of prevalent human diseases,namely,neovascular age-related macular degeneration,corneal neovascularization,colorectal cancer,fibrosarcoma and peripheral arterial ischemic disease.Angioinhibition was mediated by the Fc region of IVIg,required FcγRI and had similar potency in transgenic mice expressing human FcγRs.Finally,IVIg therapy administered to humans for the treatment of inflammatory or autoimmune diseases reduced kidney and muscle blood vessel densities.These data place IVIg,an agent approved by the US Food and Drug Administration,as a novel angioinhibitory drug in doses that are currently administered in the clinical setting.In addition,they raise the possibility of an unintended effect of IVIg on blood vessels. | Reo Yasuma Valeria Cicatiello Takeshi Mizutani Laura Tudisco Younghee Kim Valeria Tarallo Sasha Bogdanovich Yoshio Hirano Nagaraj Kerur Shengjian Li Tetsuhiro Yasuma Benjamin J Fowler Charles B Wright Ivana Apicella Adelaide Greco Arturo Brunetti Balamurali K Ambati Sevim Barbasso Helmers Ingrid E Lundberg Ondrej Viklicky Jeanette HW Leusen J Sjef Verbeek Bradley D Gelfand Ana Bastos-Carvalho Sandro De Falco Jayakrishna Ambati | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 3 |
| 6 | SGP、BCTMP的应用显示文摘 | PAGNAR LUNDBERG | 2004 | 中华纸业2004，25，2： | 3 |
| 7 | 膳食硝酸盐通过减少交感神经过度激活的机制降低血管紧张素Ⅱ诱导的高血压大鼠的血压显示文摘几项实验和临床研究表明,膳食中添加硝酸盐可提高一氧化氮的生物利用度。在口腔中,共生细菌将硝酸盐还原成亚硝酸盐,其随后被吸收到循环中,通过酶系统还原为一氧化氮。已知增加硝酸盐-亚硝酸盐-一氧化氮途径可以改善心血管、肾脏和代谢功能,并且交感神经兴奋有助于疾病的进展,但是膳食硝酸盐对交感神经活动的潜在影响仍有待阐明。 | 刘莉 叶鹏 ■ DD Cruz JC ■ A Zhuge Z Marques SM Naves LM Persson AEG Weitzberg E Lundberg JO Balarini CM Pedrino GR Braga VA ■ M | 2019 | 中华高血压杂志2019，0，3： | 2 |
| 8 | Dietary inorganic nitrate mobilizes circulating angiogenic cells显示文摘 | Christian Heiss Christian Meyer Matthias Totzeck Ulrike B. Hendgen-Cotta Yvonne Heinen Peter Luedike Stefanie Keymel Nassim Ayoub Jon O. Lundberg Eddie Weitzberg Malte Kelm Tienush Rassaf | 2012 | Free Radical Biology and Medicine2012，，9： | 2 |
| 9 | The effect of Ga-grading in CIGS thin film solar cells显示文摘 | O. Lundberg M. Edoff L. Stolt | 2004 | Thin Solid Films2004，，： | 2 |
| 10 | Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin显示文摘 | Lundberg J A Franco-cereceda A Hua X Y | 1985 | Eur J pharmacol1985，108，3： | 2 |
| 11 | 老年女性蔬菜硝酸盐的摄入与颈动脉粥样硬化和缺血性脑血管病的相关性显示文摘膳食硝酸盐的短期增加可通过形成一氧化氮和其他氮氧化物来改善血管健康。其是否可降低长期血管疾病风险尚未得到验证,为了明确这一点,Bondonno教授团队调查了植物来源的硝酸盐摄入与老年女性颈总动脉内膜中层厚度(common carotid artery intimamedia thickness,CCA-IMT)、斑块严重程度和缺血性脑血管疾病事件的关系(n=1226),方法:纳入研究对象,确定基线时(1998年)的蔬菜硝酸盐摄入量、生活方式因素和心血管病危险因素。 | 刘莉 叶鹏 Bondonno CP Blekkenhorst LC Prince RL Ivey KL Lewis JR Devine A Woodman RJ Lundberg JO Croft KD Thompson PL Hodgson JM | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 12 | ^31p and ^14N NMR studies of the up take of phosphorus and nitro- gen compounds in the marine macroalgae Ulva lactuca 显示文摘 | Lundberg P Welch R G Jansen P etal | 1989 | Plant Physiol1989，89，： | 1 |
| 13 | Spelenthems and climate:a special issue of the Holocene显示文摘 | Lundberg J | 1999 | The Holocene1999，9，6： | 1 |
| 14 | ^13C NMR spectroscopy studies of forest soil microbial activity: glucose uptake and fatty acid biosynthesis显示文摘 | Lundberg P Ekblad A Nilsson M | 2001 | Soil Biology & Biochemistry2001，33，： | 1 |
| 15 | Survival,integration,and differentiation of neural stem cell lines after transplantation to the adult rat striatum显示文摘 | Lundberg C Martinez-Serrano A Cattaneo E | 1997 | Exp Neurol1997，145，： | 1 |
| 16 | Creation of human tumour cells with defined genetic elements显示文摘 | Hahn WC Counter CM Lundberg AS | 1999 | Nature1999，400，： | 1 |
| 17 | Auditory function after spinal anesthesia显示文摘 | Wang LP Magnusson M Lundberg J | 1993 | Reg Anesth1993，18，3： | 1 |
| 18 | Decreased expression of interlueukin-1α interlueukin-1β,and cell adhesion molecules in muscle tissues following corticosteroid treatment in patients with polymyositis and dermatomyositis 显示文摘 | Lundberg I Kratz AK Alexandersan H | 2000 | Arthritis Rheum2000，43，2： | 1 |
| 19 | Conjugation of an anti-B-cell lymphoma monoclonal antibody, LL2, to long- circulating drug-carrier lipid emulsions 显示文摘 | Lundberg BB Griffiths G Hansen HJ | 1999 | J Pharm Pharmacol1999，51，10： | 1 |
| 20 | Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6 显示文摘 | Hack MA Sugimori M Lundberg C | 2004 | Mol Cell Neurosci2004，25，4： | 1 |
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