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| 1 | Convergence Analysis of a Block-by-Block Method for Fractional Differential Equations显示文摘The block-by-block method,proposed by Linz for a kind of Volterra integral equations with nonsingular kernels,and extended by Kumar and Agrawal to a class of initial value problems of fractional differential equations(FDEs)with Caputo derivatives,is an efficient and stable scheme.We analytically prove and numerically verify that this method is convergent with order at least 3 for any fractional order indexα>0. | Jianfei Huang Yifa Tang Luis Vázquez | 2012 | Numerical Mathematics(Theory,Methods and Applications)2012，5，2： | 11 |
| 2 | Direct-fed microbes: A tool for improving the utilization of low quality roughages in ruminants显示文摘For many years, ruminant nutritionists and microbiologists have been interested in manipulating the microbial ecosystem of the rumen to improve production efficiency of different ruminant species. Removal and restriction of antibiotics subtherapeutic uses from ruminant diets has amplified interest in improving nutrient utilization and animal performance and search for more safe alternatives. Some bacterial and fungal microorganisms as a direct-fed microbial(DFM) can be the most suitable solutions. Microorganisms that are commonly used in DFM for ruminants may be classified mainly as lactic acid producing bacteria(LAB), lactic acid utilizing bacteria(LUB), or other microorganism's species like Lactobacillus, Bifidobacterium, Enterococcus, Streptococcus, Bacillus, Propionibacterium, Megasphaera elsdenii and Prevotellabryantii, in addition to some fungal species of yeast such as Saccharomyces and Aspergillus. A definitive mode of action for bacterial or fungal DFM has not been established; although a variety of mechanisms have been suggested. Bacterial DFM potentially moderate rumen conditions, and improve weight gain and feed efficiency. Fungal DFM may reduce harmful oxygen from the rumen, prevent excess lactate production, increase feed digestibility, and alter rumen fermentation patterns. DFM may also compete with and inhibit the growth of pathogens, immune system modulation, and modulate microbial balance in the gastrointestinal tract. Improved dry matter intake, milk yield, fat corrected milk yield and milk fat content were obtained with DFM administration. However, the response to DFM is not constant; depending on dosages, feeding times and frequencies, and strains of DFM. Nonetheless, recent studies have supported the positive effects of DFM on ruminant performance. | Mona M Y Elghandour Abdelfattah Z M Salem Jose S Martínez Castaeda Luis M Camacho Ahmed E Kholif Juan C Vázquez Chagoyán | 2015 | Journal of Integrative Agriculture2015，14，3： | 7 |
| 3 | Thiopurine-methyltransferase variants in inflammatory bowel disease:Prevalence and toxicity in Brazilian patients显示文摘AIM:To analyze the prevalence of thiopurine-methyltransferase(TPMT)genotypes and their associationwith drug toxicity in inflammatory bowel disease(IBD)patients from southeastern Brazil.METHODS:A total of 219 consecutive patients with IBD,of which 146 had Crohn’s disease and 73 had ulcerative colitis,regularly seen at the outpatient unit of the Division of Gastroenterology at the University Hospital Pedro Ernesto of the State University of Rio de Janeiro,a tertiary referral center,were enrolled in this study from February 2009 to January 2011.We analyzed the presence of major TPMT genetic variants(TPMT*2,*3A,*3C)in IBD patients by means of a specific allele and RFLP-PCR.Genomic DNA was isolated from peripheral blood leukocytes by proteinase-K/Sodium Dodecyl Sulfate digestion and phenol-chloroform extraction.TPMT*2(C238G),TPMT*3A(G460A/A719G),and TPMT*3C(A719G)genotypes were detected by real-time polymerase chain reaction followed by direct sequencing with specific primers.Clinical data were systematically recorded,and correlated with the genotype results.RESULTS:The distribution of the selected TPMT gene polymorphism TPMT*2(C238G),TPMT*3A(G460A/A719G),and TPMT*3C(A719G)genotypes was 3.6%,5.4%,and 7.7%of the patients,respectively.Among the side effects recorded from patients taking azathioprine,14 patients presented with pancreatitis and/or an elevation of pancreatic enzymes,while 6 patients had liver toxicity,and 2 patients exhibited myelosuppression/neutropenia.TPMT polymorphisms were detected in 37/219 patients(8 heterozygous for*2,11 heterozygous for*3A,and 18 heterozygous for*3C).No homozygotic polymorphisms were found.Despite the prevalence of the TPMT*3C genotype,no differences among the genotype frequencies were significant.Although no association was detected regarding myelotoxicity or hepatotoxicity,a trend towards the elevation of pancreatic enzymes was observed for TPMT*2 and TPMT*3C genotypes.CONCLUSION:The prevalence of TPMT genotypes was high among Brazilian patients.Variants genes*2and*3C may be associated with azathioprine pancreatic toxicity in a IBD southeastern Brazilian population. | Ana Teresa P Carvalho Barbara C Esberard Renata S B Fróes Davy C M Rapozo Ana B Grinman Tatiana A Simo Juliana C V C Santos Antonio José V Carneiro Luis Felipe Ribeiro-Pinto Heitor S P de Souza | 2014 | World Journal of Gastroenterology2014，20，12： | 3 |
| 4 | Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding显示文摘 | Emilio Estévez Benito González-Conde José Luis Vázquez-Iglesias Maria de los Angeles Vázquez-Millán Sonia Pértega Pedro A. Alonso Joan Clofent Eva Santos José Luis Ulla Eloy Sánchez | 2006 | European Journal of Gastroenterology & Hepatology2006，，8： | 3 |
| 5 | A NEW APPROACH TO SOLVE SYSTEMS OF LINEAR EQUATIONS显示文摘We propose a new iterative approach to solve systems of linear equations. The new strategy integrates the algebraic basis of the problem with elements horn classical mechanics all the finite difference method. The approach defines two families of convergent iterative methods. Each family is characterized by a linear differential equation, and every method is obtained from a suitable hoe difference scheme to integrate the associated dif ferential equation. The methods are general and depend on neither the matrix dimension nor the matrix structure. In this preliminary work, we present the basic features of the method with a simple application to a low dimensional system. | V á squez, Luis V á squez-Poletti, Jos é L. | 2001 | Journal of Computational Mathematics2001，19，4： | 2 |
| 6 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 7 | Noether conserved quantities and Lie point symmetries of difference Lagrange-Maxwell equations and lattices显示文摘This paper presents a method to find Noether-type conserved quantities and Lie point symmetries for discrete mechanico-electrical dynamical systems,which leave invariant the set of solutions of the corresponding difference scheme.This approach makes it possible to devise techniques for solving the Lagrange-Maxwell equations in differences which correspond to mechanico-electrical systems,by adapting existing differential equations.In particular,it obtains a new systematic method to determine both the one-parameter Lie groups and the discrete Noether conserved quantities of Lie point symmetries for mechanico-electrical systems.As an application,it obtains the Lie point symmetries and the conserved quantities for the difference equation of a model that represents a capacitor microphone. | 傅景礼 聂宁明 黄健飞 Jiménez Salvador 唐贻发 Vzquez Luis 赵维加 | 2009 | Chinese Physics B2009，18，7： | 2 |
| 8 | Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients显示文摘 | Manuel Romero-Gómez Maria Del Mar Viloria Raúl J. Andrade Javier Salmerón Moisés Diago Conrado M. Fernández-Rodríguez Raquel Corpas Marina Cruz Lourdes Grande Luis Vázquez Paloma Mu?oz-de-Rueda Pilar López-Serrano Ana Gila María L. Gutiérrez Celia Pérez A | 2005 | Gastroenterology2005，，3： | 2 |
| 9 | Prokineticin-1 (Prok-1) works coordinately with glial cell line derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells显示文摘 | Ngan E S Shum C K Poon H C Sham M H Garcia-Barcelo M M Lui V C | 2008 | Biochim Biophys Acta2008，1783，： | 1 |
| 10 | Awireless controller to enhance dynamic performance of parallel inverters in distributed generation system显示文摘 | Guerrero J M Luis Garcia de V Jose M | 2004 | IEEE Transactions on Power Electronics2004，19，5： | 1 |
| 11 | Chitosan and Chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as noval carriers for proteins and vaccines显示文摘 | PILAR C CARMEN R L JOSE LUIS V J | 1997 | Pharm Res1997，14，10： | 1 |
| 12 | Is Gum Chewing Useful for Ileus After Elective Colorectal Surgery? A Systematic Review and Meta-Analysis of Randomized Clinical Trials显示文摘 | Wenceslao Vásquez Adrián V. Hernández Jose Luis Garcia-Sabrido | 2009 | Journal of Gastrointestinal Surgery2009，，4： | 1 |
| 13 | CREB3L2- PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis 显示文摘 | Lui WO Zeng L Rehrmann V Deshpande S | 2008 | Cancer Res2008，68，17： | 1 |
| 14 | Involvement of DNA methylation in tree development and micropropagation显示文摘 | Luis V Rodrigo H Monica M | 2007 | Plant Cell Tiss Organ Cult2007，91，2： | 1 |
| 15 | Nuclear co-expression of p14 ^{ARF} and p16 ^{INK4A} in uterine cervical cancer-derived cell lines containing HPV显示文摘 | Salvador Vázquez-Vega Lilia Patricia Sánchez-Suárez Adriana Contreras-Paredes Emilio Castellanos-Juárez Rubicelia Pe?arroja-Flores Marcela Lizano-Soberón Rafael Andrade-Cruz Alejandro García-Carrancá Luis Benítez-Bribiesca | 2010 | Cancer Biomarkers2010，，6： | 1 |
| 16 | Prehnite-pumpellyite ~acies metamorphism in the Cenozoic Abanico Formation,Andes of central Chile (33~50'S) :chemical and scale controls on mineral assemblages, reaction progress and the equilibrium state显示文摘 | Marcia M Luis /~ Mario V | 2010 | Andean Geology2010，37，1： | 1 |
| 17 | Casale, Carlos Flavion, Miguel Guinalfu, Understanding the Intention to Follow the Advice Obtained in an Online Travel Community 显示文摘 | Luis V | 2011 | Computers in Human Behavior2011，，2： | 1 |
| 18 | Derivative-free optimization: a review of algorithms and comparison of software implementations 显示文摘 | Luis M R Nikolaos V S | 2013 | Journal of Global Optimization2013，56，3： | 1 |
| 19 | Operational space trajectory tracking control of robot manipulators endowed with a primary controller of synthetic joint velocity 显示文摘 | Javier M V Luis G H | 2011 | ISATransactions(S0019-0578)2011，50，： | 1 |
| 20 | An optimiza- tion methodology of alkaline - surfactant - polymer flooding processes using field scale numerical simulation and multiple sur- rogates 显示文摘 | LUIS E Z NESTOR V Q T SALVADOR P | 2005 | Journal of Petroleum Science and Engineering2005，47，： | 1 |
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