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| 1 | Cancer immunosurveillance: role of patrolling monocytes显示文摘 | Luca Cassetta Jeffrey W Pollard | 2016 | Cell Research2016，26，1： | 5 |
| 2 | Antenna-assisted picosecond control of nanoscale phase transition in vanadium dioxide显示文摘Nanoscale devices in which the interaction with light can be configured using external control signals hold great interest for next-generation optoelectronic circuits.Materials exhibiting a structural or electronic phase transition offer a large modulation contrast with multi-level optical switching and memory functionalities.In addition,plasmonic nanoantennas can provide an efficient enhancement mechanism for both the optically induced excitation and the readout of materials strategically positioned in their local environment.Here,we demonstrate picosecond all-optical switching of the local phase transition in plasmonic antenna-vanadium dioxide(VO_(2))hybrids,exploiting strong resonant field enhancement and selective optical pumping in plasmonic hotspots.Polarization-and wavelength-dependent pump–probe spectroscopy of multifrequency crossed antenna arrays shows that nanoscale optical switching in plasmonic hotspots does not affect neighboring antennas placed within 100 nm of the excited antennas.The antenna-assisted pumping mechanism is confirmed by numerical model calculations of the resonant,antenna-mediated local heating on a picosecond time scale.The hybrid,nanoscale excitation mechanism results in 20 times reduced switching energies and 5 times faster recovery times than a VO_(2) film without antennas,enabling fully reversible switching at over two million cycles per second and at local switching energies in the picojoule range.The hybrid solution of antennas and VO_(2) provides a conceptual framework to merge the field localization and phase-transition response,enabling precise,nanoscale optical memory functionalities. | Otto L Muskens Luca Bergamini Yudong Wang Jeffrey M Gaskell Nerea Zabala CH de Groot David W Sheel Javier Aizpurua | 2016 | Light(Science & Applications)2016，5，1： | 5 |
| 3 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 4 | Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex显示文摘在发炎和白血球过多症之间的潜在的交叉连接有一段时间被讨论了,但是支持这教义的试验性的证据是少见的。特别地,由煽动性的调停人理解为 proto-oncogenic 生长因素表情的潜在的 upregulation 负责的机制是重要的。这里,我们调查了高度煽动性的 cytokine interleukin-1 贝它的能力(IL-1β) 到导致干细胞因素(SCF ) 的生产,它是在造血的 myeloid 细胞的恶意的转变之上控制尖锐 myeloid 白血球过多症的前进的一个主要造血的生长因素。我们发现了那人的 IL-1β在 MCF-7 人的上皮的乳癌房间和那导致了 SCF 的表示 / 分泌物这个过程取决于组织缺氧可诱导的因素 1 (HIF-1 ) 抄写建筑群。我们也表明了 phosphatidylinositol-3 kinase (PI-3K ) 的一个关键角色 rapamycin (mTOR ) 的 /mammalian 目标在 IL-1β 的小径;导致的 HIF-1α在 MCF-7 房间的累积。重要地, mTOR 也被发现在 IL-1β 起一个作用;导致的 SCF 生产。而且,为 IL-1β 的积极关联的一个趋势;并且在健康人的施主的血浆的 SCF 层次被观察。总的来说,我们的结果表明那 IL-1β,它通常衔接天生、适应的免疫,通过 PI-3K/mTOR 小径和 HIF-1 抄写建筑群导致主要 haematopoietic/proleukaemic 生长因素 SCF 的生产。这些调查结果强烈支持在发炎和尖锐 myeloid 白血球过多症之间的串音。 | Rafal W Wyszynski Bernhard F Gibbs Luca Varani Daniela Iannotta Vadim V Sumbayev | 2016 | Cellular & Molecular Immunology2016，13，1： | 2 |
| 5 | The past,present,and future of single-port urology?显示文摘In this manuscript,Ju et al.1 sought to compare short-term perioperative outcomes between extraperitoneal robotic single-port radical prostatectomy(epR-spRP)and extraperitoneal robotic multiport radical prostatectomy(epR-mpRP)utilizing a multi-channel laparoscopic port and the da Vinci Si robotic platform.In this comparison,several potential advantages of single-site surgery including median hospital stay,pain scores,and surgical scar cosmesis favored the spRP arm.While this study represents a relatively small sample size in both cohorts,the authors should be commended for a novel approach to executing a single-site robotic prostatectomy without the availability of the da Vinci Si platform. | Luca A Morgantini Simone Crivellaro Ryan W Dobbs | 2021 | Asian Journal of Andrology2021，23，6： | 2 |
| 6 | Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis显示文摘 | Phil A Hart Terumi Kamisawa William R Brugge Jae Bock Chung Emma L Culver László Czakó Luca Frulloni Vay Liang W Go Thomas M Gress Myung-Hwan Kim Shigeyuki Kawa Kyu Taek Lee Markus M Lerch Wei-Chih Liao Matthias L?hr Kazuichi Okazaki Ji Kon Ryu Nicolas Sc | 2013 | Gut2013，，12： | 2 |
| 7 | On the Measurement of Stress-strain Curves by Spherical Indentation显示文摘 | E G Herbert G M Pharr W C Oliver B N Lucas J L Hay | 2001 | Thin Solid Films2001，，： | 1 |
| 8 | Activating flux increasing the performance and productivity of the TIG and plasma processes显示文摘 | Lucas W Howse D | 1996 | Welding and Metal Fabrication1996，，1： | 1 |
| 9 | Indentation power-law creepof high-purity indium 显示文摘 | LUCAS B N OLIVER W C | 1999 | Metallurgical and MaterialsTransactions A1999，30，3： | 1 |
| 10 | Efficient nearly orthogonal and space-filling latin hypereubes 显示文摘 | Cioppa T M Lucas T W | 2007 | Technometrics2007，49，1： | 1 |
| 11 | Activating flux -increasing the performance and productivity of the TIG and plasma processes 显示文摘 | LUCAS W | 1996 | Welding and Metal Fabrication1996，，1： | 1 |
| 12 | LRFD for Steel and Composite Beams with Web Openings 显示文摘 | Darwin D Lucas W K | 1990 | Journal of Structural Engineering1990，116，6： | 1 |
| 13 | Particle and gasemissions from a simulated coal-burning household fire pit 显示文摘 | Tian L W Lucas D Fischer S L | 2008 | Environmental Science & Technology2008，42，7： | 1 |
| 14 | Expression of a inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA显示文摘 | Schachtman D P Schroeder J I Lucas W | 1992 | Science1992，258，： | 1 |
| 15 | How do viruses traffic on the vascular highway' 显示文摘 | Gilbertson R L Lucas W J | 1996 | Trends Plant Sci1996，1，： | 1 |
| 16 | Workshop summary:Nutrition of the extremely low birth weight infant 显示文摘 | Hay W Jr Lucas A Herid W C | 1999 | Pediatrics1999，10，4960： | 1 |
| 17 | The 6-minute walk and peak oxygen consumption in advanced heart failure:aerobic capacity and survival显示文摘 | Lucas C Stevenson LW Johnson W | 1999 | Am Heart J1999，138，： | 1 |
| 18 | Activating flux-improving the performance of the TIG process显示文摘 | Lucas W | 2000 | Welding and Metal Fabrication2000，68，2： | 1 |
| 19 | Welding Engineering Expert System and Multimedia Computer Programs显示文摘 | Lucas W | 1995 | Welding & Metal Fabrication1995，，4： | 1 |
| 20 | Integrative plant biology: Role of phloem long-distance macromolecular tmfficking显示文摘 | Lough H Lucas W J | 2006 | Annum Rev Plant Biol2006，57，： | 1 |
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