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| 1 | Portal vein thrombosis:Insight into physiopathology,diagnosis,and treatment显示文摘Portal vein thrombosis (PVT) is a relatively common complication in patients with liver cirrhosis, but might also occur in absence of an overt liver disease. Several causes, either local or systemic, might play an important role in PVT pathogenesis. Frequently, more than one risk factor could be identified; however, occasionally no single factor is discernable. Clinical examination, laboratory investigations, and imaging are helpful to provide a quick diagnosis, as prompt treatment might greatly affect a patient's outcome. In this review, we analyze the physiopathological mechanisms of PVT development, together with the hemodynamic and functional alterations related to this condition. Moreover, we describe the principal factors most frequently involved in PVT development and the recent knowledge concerning diagnostic and therapeutic procedures. Finally, we analyze the implications of PVT in the setting of liver transplantation and its possible influence on patients' future prognoses. | Francesca R Ponziani Maria A Zocco Chiara Campanale Emanuele Rinninella Annalisa Tortora Luca Di Maurizio Giuseppe Bombardieri Raimondo De Cristofaro Anna M De Gaetano Raffaele Landolfi Antonio Gasbarrini | 2010 | World Journal of Gastroenterology2010,16,2: | 75 |
| 2 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015,5,1: | 6 |
| 3 | Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis显示文摘 | Phil A Hart Terumi Kamisawa William R Brugge Jae Bock Chung Emma L Culver László Czakó Luca Frulloni Vay Liang W Go Thomas M Gress Myung-Hwan Kim Shigeyuki Kawa Kyu Taek Lee Markus M Lerch Wei-Chih Liao Matthias L?hr Kazuichi Okazaki Ji Kon Ryu Nicolas Sc | 2013 | Gut2013,,12: | 2 |
| 4 | Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn’s disease patients显示文摘AIM:To investigate the interaction of interleukin-23 receptor(IL23R)(rs1004819 and rs2201841),autophagy-related 16-like 1(ATG16L1)(rs2241880), caspase recruitment domain-containing protein 15 (CARD15)genes,and IBD5 locus in Crohn's disease(CD) patients. METHODS:A total of 315 unrelated subjects with CD and 314 healthy controls were genotyped.Interactions and specific genotype combinations of a total of eight variants were tested.The variants of IBD5locus(IGR2198a_1 rs11739135 and IGR2096a_1 rs12521868),CARD15(R702W rs2066845 and L1007fs rs2066847),ATG16L1(rs2241880)and IL23R (rs1004819,rs2201841)genes were genotyped by PCR-RFLP,the G908R(rs2066844)in CARD15 was determined by direct sequencing. RESULTS:The association of ATG16L1 T300A with CD was confirmed[P=0.004,odds ratio(OR)=1.69, 95%CI:1.19-2.41],and both IL23R variants were found to represent significant risk for the disease(P= 0.008,OR=2.05,95%CI:1.20-3.50 for rs1004819 AA;P<0.001,OR=2.97,95%CI:1.65-5.33 for rs2201841 CC).Logistic regression analysis of pairwise interaction of the inflammatory bowel disease (IBD)loci indicated that IL23R,ATG16L1,CARD15 and IBD5(IGR2198a_1)contribute independently to disease risk.We also analysed the specific combina- tions by pair of individual ATG16L1,IL23R rs1004819, rs2201841,IGR2198a_1,IGR2096a_1 and CARD15 genotypes for disease risk influence.In almost all cases,the combined risk of susceptibility pairs was higher in patients carrying two different risk-associated gene variants together than individuals with just one polymorphism.The highest OR was found for IL23R rs2201841 homozygous genotype with combination of positive CARD15 status(P<0.001,OR=9.15,95% CI:2.05-40.74). CONCLUSION:The present study suggests a cumulative effect of individual IBD susceptibility loci. | Veronika Csngei Luca Járomi EnikSáfrány Csilla Sipeky Lili Magyari Bernadett Faragó Judit Bene Noémi Polgár Lilla Lakner Patrícia Sarlós Márta Varga Béla Melegh | 2010 | World Journal of Gastroenterology2010,16,2: | 2 |
| 5 | Culture of human epithelium显示文摘 | De luca M Canc edda R | 1992 | Burns1992,18,1: | 1 |
| 6 | Preoperative lanreotide treatment for GH-secreting pituitary adenomas:effect on tumour volume and predictive factors of significant tumour shrinkage显示文摘 | Lucas T Astorga R Catala M | 2003 | Clin Endocrinol2003,58,4: | 1 |
| 7 | Intelligent modeling and control of washing machine using locally linear neuro-fuzzy ( LL- NF) modeling and modified brain emotional learning based Intel- ligent controller(BELBIC) 显示文摘 | LUCAS C MILASI R M ARAABI B N | 2006 | Asian Journal of Control2006,8,4: | 1 |
| 8 | Incidence of early neonatal mortality and morbidity after late - preterm and term cesarean delivery 显示文摘 | De Luca R Boulvain M Irion O | 2009 | Pediatrics2009,123,6: | 1 |
| 9 | Intelligent washing ma- x chine : a bioinspired and multi-objective approach 显示文摘 | MILASI R M JAMALI M R LUCAS C | 2007 | Interna- tional Journal of Control Automation and Systems2007,5,4: | 1 |
| 10 | Subjective Weil-Being:Three Decades of Progress显示文摘 | Diener E Suh E M Lucas R E | | 0,,02: | 1 |
| 11 | Antioxidant response to NaCI stress in sah-tolerant and sahsensitive cultivars of cotton显示文摘 | Gossett D R Millhollon E P Lucas M C | 1994 | Crop Sci1994,34,: | 1 |
| 12 | A Study of Current Logic Design Prac- tices in the Automotive Manufacturing Industry显示文摘 | Lucas M R Ilbury D M | 2003 | International Journal of Human-computer Studies2003,59,5: | 1 |
| 13 | Spreadsheet Analysis and Design显示文摘 | Ronen B Palley M A Lucas H C J R | 1989 | Communications of the ACM1989,32,1: | 1 |
| 14 | Subjective well-be- ing:Three decades of progress 显示文摘 | Diener E d Suh E M Lucas R | 1999 | Psychological Bulle- tin1999,125,2: | 1 |
| 15 | Implementation of emotional controller for Interior permanent-magnet synchronous motor drive 显示文摘 | RAHMAN M A MILASI R M LUCAS C | 2008 | IEEE Transactions on Industry Applications2008,44,5: | 1 |
| 16 | Motion control of omni-directional three-wheel robots by brain-emotional-learning- based Intelligent controller 显示文摘 | SHARBAFI M A LUCAS C DANESHVAR R | 2010 | IEEE Transactions on Systems Man and cybernetics2010,40,6: | 1 |
| 17 | A new genetic algorithm with Lamarckian individual learning for generation scheduling显示文摘 | Mashhadi H R Shanechi H M Lucas C | 2003 | IEEE Trans on Power Apparatus Systems2003,18,3: | 1 |
| 18 | Aerated Flow Char- acteristics of Skimming Flow over Stepped Chutes 显示文摘 | BOES R M LUCAS J HAGER W H | 2013 | Journal o Hydraulic Research2013,51,6: | 1 |
| 19 | Crosscultural variations in predictors of life satisfaction : Perspectives from needs and values显示文摘 | OISHI S DIENER E F LUCAS R E SUH E M | 1999 | Personality and Social Psychology Bulletin1999,25,: | 1 |
| 20 | The draft genome of watermelon (Citrullus lanatus ) and reseqnencing of 20 diverse accessions显示文摘 | Guo S G Zhang J G Sun H H Salse J Lucas W J Zhang H Y Zheng Y Mao L Y Ren Y WangZ W Min J M Guo X S Murat F Ham B K Zhang Z L Gao S Huang M Xu Y M Zhong S L Bombarely A Mueller L Zhao H He H Q Zhang Y Zhang Z H Huang S W Tan T Pang E Lin K Hu Q Kuang H H Ni P X Wang B Liu J G Kou Q H Hou W J Zou X H Jiang J Gong G Y Klee K Schoof H Huang Y Hu X S Dong S S Liang D Q Wang J Wu K Xia Y Zhao X Zheng Z Q Xing M Liang X M Huang B Q Lv T Wang J Y Yin Y Yi H P Li R Q Wu M Z Levi A Zhang X P Giovannoni J Wang J Li YF Fei Z J Xu Y | 2013 | Nature genetics2013,45,1: | 1 |