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| 1 | mTERF5 Acts as a Transcriptional Pausing Factor to Positively Regulate Transcription of Chloroplast psbEFLJ显示文摘RNA polymerase transcriptional pausing represents a major checkpoint in transcription in bacteria and metazoans,but it is unknown whether this phenomenon occurs in plant organelles.Here,we report that transcriptional pausing occurs in chloroplasts.We found that mTERF5 specifically and positively regulates the transcription of chloroplast psbEFLJ in Arabidopsis thaliana that encodes four key subunits of photosystem II.We found that mTERF5 causes the plastid-encoded RNA polymerase(PEP)complex to pause at psbEFLJ by binding to the+30 to+51 region of double-stranded DNA.Moreover,we revealed that mTERF5 interacts with pTAC6,an essential subunit of the PEP complex,although pTAC6 is not involved in the transcriptional pausing at psbEFLJ.We showed that mTERF5 recruits additional pTAC6 to the transcriptionally paused region of psbEFLJ,and the recruited pTAC6 proteins could be assembled into the PEP complex to regulate psbEFLJ transcription.Taken together,our findings shed light on the role of transcriptional pausing in chloroplast transcription in plants. | Shunhua Ding Yi Zhang Zhi Hu Xiahe Huang Bohan Zhang Qingtao Lu Xiaogang Wen Yingchun Wang Congming Lu | 2019 | Molecular Plant2019，12，9： | 6 |
| 2 | Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression显示文摘Dear Editor,F0XA1,a forkhead(FKHD)family transcription factor,is highly expressed in the epithelium of endoderm-derived organs, including the prostate gland.1 Transgenic mouse studies have shown that F0XA1 expression is required for prostate epithelial cell differentiation and ductal morphogenesis during development and for the maintenance of this differentiated epithelial phenotype in the adult. Mechanistically, F0XA1 binds FKHD motifs in the DNA to open chromatin and in crease local accessibility. | Bohan Xu Bing Song Xiaodong Lu Jung Kim Ming Hu Jonathan C.Zhao Jindan Yu | 2019 | Cell Research2019，29，9： | 4 |
| 3 | Location and allocation problem for spare parts depots on integrated logistics support显示文摘In equipment integrated logistics support(ILS), the supply capability of spare parts is a significant factor. There are lots of depots in the traditional support system, which makes too many redundant spare parts and causes high cost of support. Meanwhile,the inconsistency among depots makes it difficult to manage spare parts. With the development of information technology and transportation, the supply network has become more efficient. In order to further improve the efficiency of supply-support work and the availability of the equipment system, building a system of one centralized depot with multiple depots becomes an appropriate way.In this case, location selection of the depots including centralized depots and multiple depots becomes a top priority in the support system. This paper will focus on the location selection problem of centralized depots considering ILS factors. Unlike the common location selection problem, depots in ILS require a higher service level. Therefore, it becomes desperately necessary to take the high requirement of the mission into account while determining location of depots. Based on this, we raise an optimal depot location model. First, the expected transportation cost is calculated.Next, factors in ILS such as response time, availability and fill rate are analyzed for evaluating positions of open depots. Then, an optimization model of depot location is developed with the minimum expected cost of transportation as objective and ILS factors as constraints. Finally, a numerical case is studied to prove the validity of the model by using the genetic algorithm. Results show that depot location obtained by this model can guarantee the effectiveness and capability of ILS well. | WEN Meilin LU Bohan LI Shuyu KANG Rui | 2019 | Journal of Systems Engineering and Electronics2019，30，6： | 3 |
| 4 | Visual tracking via discriminative sparse similarity map显示文摘 | Zhuang Bohan Lu Huchuan Xiao Ziyang | 2014 | IEEE Transactions on Image Processing2014，23，4： | 1 |
| 5 | Visual tracking via discriminatiw~ sparse similarity map 显示文摘 | Zhuang Bohan Lu Huchuan Xiao Ziyang | 2014 | IEEE Trans on Image Processing2014，23，4： | 1 |
| 6 | Long-range gene regulation network of the MGMT enhancer modulates glioma cell sensitivity to temozolomide显示文摘Approximately 80%of primary tumors in the central nervous system are malignant glioma,and>50%of those are diagnosed as glioblastoma(GBM),the most aggressive glioma.Despite treatment advances,GBM prognosis is unsatisfying,and the median survival time of patients is only 14-17 months. | Bohan Chen Anshun He Jinfang Bi Shupeng Sun Yiping Ma Wenbin Wang Dianhao Guo Jun Chen Yuyang Qian Tengfei Shi Guohui Nie Zhongfang Zhao Jiandang Shi Hongzhen Yang Lei Zhang Wange Lu | 2021 | Journal of Genetics and Genomics2021，48，10： | 1 |
| 7 | Improved conditional differential attacks on lightweight hash family QUARK显示文摘Nonlinear feedback shift register(NFSR)is one of the most important cryptographic primitives in lightweight cryptography.At ASIACRYPT 2010,Knellwolf et al.proposed conditional differential attack to perform a cryptanalysis on NFSR-based cryptosystems.The main idea of conditional differential attack is to restrain the propagation of the difference and obtain a detectable bias of the difference of the output bit.QUARK is a lightweight hash function family which is designed by Aumasson et al.at CHES 2010.Then the extended version of QUARK was published in Journal of Cryptology 2013.In this paper,we propose an improved conditional differential attack on QUARK.One improvement is that we propose a method to select the input difference.We could obtain a set of good input differences by this method.Another improvement is that we propose an automatic condition imposing algorithm to deal with the complicated conditions efficiently and easily.It is shown that with the improved conditional differential attack on QUARK,we can detect the bias of output difference at a higher round of QUARK.Compared to the current literature,we find a distinguisher of U-QUARK/D-QUARK/S-QUARK/C-QUARK up to 157/171/292/460 rounds with increasing 2/5/33/8 rounds respectively.We have performed the attacks on each instance of QUARK on a 3.30 GHz Intel Core i5 CPU,and all these attacks take practical complexities which have been fully verified by our experiments.As far as we know,all of these results have been the best thus far. | Xiaojuan Lu Bohan Li Meicheng Liu Dongdai Lin | 2022 | Cybersecurity2022，5，3： | 0 |
| 8 | Self-Assembled Porous-Reinforcement Microstructure-Based Flexible Triboelectric Patch for Remote Healthcare显示文摘Realizing real-time monitoring of physiological signals is vital for preventing and treating chronic diseases in elderly individuals. However,wearable sensors with low power consumption and high sensitivity to both weak physiological signals and large mechanical stimuli remain challenges.Here, a flexible triboelectric patch(FTEP) based on porous-reinforcement microstructures for remote health monitoring has been reported. The porousreinforcement microstructure is constructed by the self-assembly of silicone rubber adhering to the porous framework of the PU sponge. The mechanical properties of the FTEP can be regulated by the concentrations of silicone rubber dilution. For pressure sensing, its sensitivity can be effectively improved fivefold compared to the device with a solid dielectric layer, reaching 5.93 kPa^(-1) under a pressure range of 0–5 kPa. In addition, the FTEP has a wide detection range up to 50 kPa with a sensitivity of 0.21 kPa^(-1). The porous microstructure makes the FTEP ultra-sensitive to external pressure, and the reinforcements endow the device with a greater deformation limit in a wide detection range. Finally, a novel concept of the wearable Internet of Healthcare(Io H) system for real-time physiological signal monitoring has been proposed, which could provide real-time physiological information for ambulatory personalized healthcare monitoring. | Hao Lei Haifeng Ji Xiaohan Liu Bohan Lu Linjie Xie Eng Gee Lim Xin Tu Yina Liu Peixuan Zhang Chun Zhao Xuhui Sun Zhen Wen | 2023 | Nano-Micro Letters2023，15，7： | 0 |
| 9 | Regulated deficit irrigation:an effective way to solve the shortage of agricultural water for horticulture显示文摘The deficient agricultural water caused by water shortage is a crucial limiting factor of horticultural production.Among many agricultural water-saving technologies,regulated deficit irrigation(RDI)has been proven to be one of the effective technologies to improve water use efficiency and reduce water waste on the premise of maintaining the quality of agricultural products.RDI was first reported more than 40years ago,although it has been applied in some areas,little is known about understanding of the implementation method,scope of application and detailed mechanism of RDI,resulting in the failure to achieve the effect that RDI should have.This review refers to the research on RDI in different crops published in recent years,summarizes the definition,equipment condition,function,theory illumination,plant response and application in different crops of RDI,and looks forward to its prospect.We expect that this review will provide valuable guidance for researchers and producers concerned,and support the promotion of RDI in more horticultural crops. | Bohan Yang Peining Fu Jiang Lu Fengwang Ma Xiangyu Sun Yulin Fang | 2022 | Stress Biology2022，2，1： | 0 |
| 10 | Diffusion effect on the decay of time-resolved photoluminescence under low illumination in lead halide perovskites显示文摘Time-resolved photoluminescence(TRPL)has been extensively used to measure the carrier lifetime in lead halide perovskites.The TRPL curves of perovskite materials are usually fitted with a multi-exponential function,instead of a single exponential one.This was considered to be a result of the surface and the bulk recombination or the additional radiative recombination caused by the high excited carrier density.Here,a new model considering the diffusion and the trap-assisted recombination of carriers is proposed to explain the TRPL curves.The expressions of the TRPL curves and the transient absorption(TA)dynamic curves are theoretically derived,demonstrating that the TRPL curve is an infinite exponential series,regardless of the presence of surface recombination or not.Our newly developed highly sensitive nanosecond TA and TRPL were employed to measure the carrier dynamics of the same sample under low illumination in the linear response region of TA,thereby experimentally verifying our model.These results suggest that the decay of the TRPL is not only a consequence of the carrier recombination but also the carrier diffusion.TRPL cannot provide a direct measurement of the carrier lifetime,whereas TA spectroscopy can.Furthermore,the surface and the bulk recombination can be resolved and the average diffusion coefficient(D)can also be correctly obtained by combining TRPL and TA measurements.We also propose an approximate method for calculating the carrier lifetime and diffusion coefficient of high-quality perovskite films.Our model provides not only a new interpretation of the dynamics of the PL decay but also a deep insight into the carrier dynamics in the nanosecond time scale under working condition of perovskites solar cells. | Huang Li Haipeng Di Xingan Wang Zefeng Ren Ming Lu An-An Liu Xueming Yang Nanlin Wang Yiying Zhao Bohan Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 0 |
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