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| 1 | Selection of Adaptive Grass and Frutex and Their Planting Benefits in the Arid-Hot Valleys of Yuanmou显示文摘In view of the environment character of the soil and content of the soil organic carbon, 278 species of grass and frutex were introduced from abroad and China, Some were selected by applied production and plantation benefit investigations. The results showed that:In the arid-hot valleys of Yuanmou the selected species showed the characteristics of fast growth and high yield (38 227.00 kg/hm2), high nutrition value (CP% content of legu-minous grass and frutex were 22.47%), as well as the strong adversity resistance to high air temperature and arid climate (soil humidity was 3.4%). The selected species not only effectively meliorated soil and increased fertility, but also improved small environment weather. | LONG Huiying SHA Yucang ZHU Hongye ZHANG Yingcui JIN Jie SHI Liangtao | 2008 | Wuhan University Journal of Natural Sciences2008，13，3： | 13 |
| 2 | Response of Artificial Grassland Carbon Stock to Management in Mountain Region of Southern Ningxia, China显示文摘Grassland is a major carbon sink in the terrestrial ecosystem. The dynamics of grassland carbon stock profoundly influence the global carbon cycle. In the published literatures so far, however, there are limited studies on the long-term dynamics and influential factors of grassland carbon stock, including soil organic carbon. In this study, spatial-temporal substitution method was applied to explore the characteristics of Medicago sativa L.(alfalfa) grassland biomass carbon and soil organic carbon density(SOCD) in a loess hilly region with different growing years and management patterns. The results demonstrated that alfalfa was the mono-dominant community during the cutting period(viz. 0–10 year). Community succession began after the abandonment of alfalfa grassland and then the important value of alfalfa in the community declined. The artificial alfalfa community abandoned for 30 years was replaced by the S. bungeana community. Accordingly, the biomass carbon density of the clipped alfalfa showed a significant increase over the time during 0–10 year. During 0–30 year, the SOCD from 0–100 cm of the soil layer of all 5 management patterns increased over time with a range between 5.300 ± 0.981 kg/m2 and 12.578 ± 0.863 kg/m2. The sloping croplands had the lowest SOCD at 5.300 ± 0.981 kg/m2 which was quite different from the abandoned grasslands growing for 30 years which exhibited the highest SOCD with 12.578 ± 0.863 kg/m2. The ecosystem carbon density of the grassland clipped for 2 years increased 0.1 kg/m2 compared with the sloping cropland, while that of the grassland clipped for 10 years substantially increased to 10.30 ± 1.26 kg/m2. Moreover, the ecosystem carbon density for abandoned grassland became 12.62 ± 0.50 kg/m2 at 30 years. The carbon density of the grassland undisturbed for 10 years was similar to that of the sloping cropland and the grassland clipped for 2 years. Different management patterns imposed great different effects on the accumulation of biomass carbon on artificial grasslands, whereas the ecosystem carbon density of the grassland showed a slight increase from the clipping to abandonment of grassland in general. | TANG Long DANG Xiaohu LIU Guobin SHAO Chuanke XUE Sha | 2014 | Chinese Geographical Science2014，24，4： | 6 |
| 3 | Consensus on the digestive endoscopic tunnel technique显示文摘With the digestive endoscopic tunnel technique(DETT), many diseases that previously would have been treated by surgery are now endoscopically curable by establishing a submucosal tunnel between the mucosa and muscularis propria(MP). Through the tunnel, endoscopic diagnosis or treatment is performed for lesions in the mucosa, in the MP, and even outside the gastrointestinal(GI) tract.At present, the tunnel technique application range covers the following:(1)Treatment of lesions originating from the mucosal layer, e.g., endoscopic submucosal tunnel dissection for oesophageal large or circular early-stage cancer or precancerosis;(2) treatment of lesions from the MP layer, per-oral endoscopic myotomy, submucosal tunnelling endoscopic resection, etc.; and(3) diagnosis and treatment of lesions outside the GI tract, such as resection of lymph nodes and benign tumour excision in the mediastinum or abdominal cavity. With the increasing number of DETTs performed worldwide, endoscopic tunnel therapeutics, which is based on DETT, has been gradually developed and optimized. However, there is not yet an expert consensus on DETT to regulate its indications, contraindications, surgical procedure, and postoperative treatment.The International DETT Alliance signed up this consensus to standardize the procedures of DETT. In this consensus, we describe the definition, mechanism,and significance of DETT, prevention of infection and concepts of DETTassociated complications, methods to establish a submucosal tunnel, and application of DETT for lesions in the mucosa, in the MP and outside the GI tract(indications and contraindications, procedures, pre-and postoperative treatments, effectiveness, complications and treatments, and a comparison between DETT and other operations). | Ning-Li Chai Hui-Kai Li En-Qiang Linghu Zhao-Shen Li Shu-Tian Zhang Yu Bao Wei-Gang Chen Philip WY Chiu Tong Dang Wei Gong Shu-Tang Han Jian-Yu Hao Shui-Xiang He Bing Hu1 Bing Hu2 Xiao-Jun Huang Yong-Hui Huang Zhen-Dong Jin Mouen A Khashab James Lau Peng Li Rui Li De-Liang Liu Hai-Feng Liu Jun Liu Xiao-Gang Liu Zhi-Guo Liu Ying-Cai Ma Gui-Yong Peng Long Rong Wei-Hong Sha Pateek Sharma Jian-Qiu Sheng Shui-Sheng Shi Dong Wan Seo Si-Yu Sun Gui-Qi Wang Wen Wang Qi Wu Hong Xu Mei-Dong Xu Ai-Ming Yang Fang Yao Hong-Gang Yu Ping-Hong Zhou Bin Zhang Xiao-Feng Zhang Ya-Qi Zhai | 2019 | World Journal of Gastroenterology2019，25，7： | 5 |
| 4 | Metal-Free C_(3)N_(4) with plentiful nitrogen vacancy and increased specific surface area for electrocatalytic nitrogen reduction显示文摘As a substitute for synthetic ammonia under mild condition, electrocatalytic nitrogen reduction reaction(NRR) provides a hopeful approach for the development of ammonia. Nevertheless, the current development of NRR electrocatalysts is far from enough and a systematic research is needed to gain a better improvement. This article presents that 2 D C_(3)N_(4)-NV with a large specific surface area and abundant nitrogen vacancies is prepared by a simple and feasible method, and used as a metal-free catalyst for electrocatalytic NRR. Experiment result and density functional theory(DFT) calculation reveal that nitrogen vacancies in 2 D C_(3)N_(4)-NV can act as an efficient active site for catalytic NRR, which is conducive to capturing and activating N_(2), lowering Gibbs free energy(DG) in reaction and inhibiting hydrogen evolution reaction(HER) at the same time. In addition, the larger specific surface area also makes more active site exposed, which is good for the contact between the electrolyte and the active site, thus enhancing its NRR activity. The electrocatalyst shows an excellent catalytic activity for NRR in 0.1 M HCl, including Faradaic efficiency of 10.96%, NH_(3) yields of 17.85 lg h^(-1) mg_(cat)^(-1)., and good stability(over 20 h). | Ziming Zhao Yu Long Sha Luo Yutong Luo Ming Chen Jiantai Ma | 2021 | Journal of Energy Chemistry2021，30，9： | 5 |
| 5 | A Teosinte-derived Allele of a MYB Transcription Repressor Confers Multiple Disease Resistance in Maize.显示文摘Natural alleles controlling multiple disease resistances (MDR) are valuable for crop breeding. However, only one MDR gene have been cloned in maize, and molecular mechanisms of MDR are not clear. By map-based cloning, we have cloned a teosinte-derived allele of a resistance gene, Mexicana lesion mimic 1 (ZmMM1), which has a lesion mimic phenotype and confers resistance to northern leaf blight (NLB), gray leaf spot (GLS) and southern corn rust (SCR). Strong MDR conferred by the teosinte allele is linked with the polymorphisms in the 3' untranslated region of the ZmMM1 gene that cause increased accumulation of ZmMM1 protein. ZmMM1 acts as a transcription repressor and negatively regulates transcription of specific target genes including ZmMM1-target gene 3 (ZmMT3), which functions as a negative regulator of plant immunity and associated cell death. The successful isolation of the ZmMM1 resistance gene will help not only in developing broad-spectrum and durable disease resistance but also in understanding the molecular mechanisms underlying MDR. | Hongze Wang Jiabao Hou Pei Ye Long Hu Junshi Huang Zhikang Dai Bao Zhang Sha Dai Jiamin Que Haoxuan Min Gengshen Chen Yanbo Wang Min Jiang Yan Liang Lin Li Xuecai Zhang Zhibing Lai | 2021 | Molecular Plant2021，14，11： | 4 |
| 6 | Biotreatment of oily wastewater by rhamnolipids in aerated active sludge system显示文摘Oily wastewater generated by various industries creates a major ecological problem throughout the world. The traditional methods for the oily wastewater treatment are inefficient and costly. Surfactants can promote the biodegradation of petroleum hydrocarbons by dispersing oil into aqueous environment. In the present study,we applied rhamnolipid-containing cell-free culture broth to enhance the biodegradation of crude oil and lubricating oil in a conventional aerobically-activated sludge system. At 20 °C,rhamnolipids (11.2 mg/L) increased the removal efficiency of crude oil from 17.7% (in the absence of rhamnolipids) to 63%. At 25 °C,the removal efficiency of crude oil was over 80% with the presence of rhamnolipids compared with 22.3% in the absence of rhamnolipids. Similarly,rhamnolipid treatment (22.5 mg/L) for 24 h at 20 °C significantly increased the removal rate of lubricating oil to 92% compared with 24% in the absence of rhamnolipids. The enhanced removal of hydrocarbons was mainly attributed to the improved solubility and the reduced interfacial tension by rhamnolipids. We conclude that a direct application of the crude rhamnolipid solution from cell culture is effective and economic in removing oily contaminants from wastewater. | Hong-zi ZHANG Xu-wei LONG Ru-yi SHA Guo-liang ZHANG Qin MENG | 2009 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2009，10，11： | 3 |
| 7 | Anode materials for potassium-ion batteries: Current status and prospects显示文摘Potassium-ion batteries(KIBs)as one of the most promising alternatives to lithium-ion batteries have been highly valued in recent years.However,progress in KIBs is largely restricted by the sluggish development in anode materials.Therefore,it is imperative to systematically outline and evaluate the recent research advances in the field of anode materials for KIBs toward promoting the development of high-performance anode materials for KIBs.In this review,the recent achievements in anode materials for KIBs are summarized.The electrochemical properties(ie.charge storage mechanism,capacity,rate performance,and cycling stability)of these reported anode materials,as well as their advantages/disadvantages,are discerned and analyzed,enabling high-performance KIBs to meet the requirements for practical applications.Finally,technological developments,scientific challenges,and future research opportunities of anode materials for KIBs are briefly reviewed. | Mo Sha Long Liu Huaping Zhao Yong Lei | 2020 | Carbon Energy2020，2，3： | 3 |
| 8 | Enhancing the microstructure and properties of titanium alloys through nitriding and other surface engineering methods显示文摘 | Ani Zhecheva Wei Sha Savko Malinov Adrian Long | 2004 | Surface & Coatings Technology2004，，7： | 2 |
| 9 | Role of MXene surface terminations in electrochemical energy storage:A review显示文摘MXenes are a group of recently discovered 2D materials and have attracted extensive attention since their first report in 2011;they have shown excellent prospects for energy storage applications owing to their unique layered microstructure and tunable electrical properties.One major feature of MXenes is their tailorable surface terminations(e.g.,-F,-O,-OH).Numerous studies have indicated that the composition of the surface terminations can significantly impact the electrochemical properties of MXenes.Nonetheless,the underlying mechanisms are still poorly understood,mainly because of the difficulties in quantitative analysis and characterization.This review summarizes the latest research progress on MXene terminations.First,a systematic introduction to the approaches for preparing MXenes is presented,which generally dominates the surface terminations.Then,theoretical and experimental efforts regarding the surface terminations are discussed,and the influence of surface terminations on the electronic and electrochemical properties of MXenes are generalized.Finally,we present the significance and research prospects of MXene terminations.We expect this review to encourage research on MXenes and provide guidance for usingthese materials for batteries and supercapacitors. | Zhuoheng Bao Chengjie Lu Xin Cao Peigen Zhang Li Yang Heng Zhang Dawei Sha Wei He Wei Zhang Long Pan Zhengming Sun | 2021 | Chinese Chemical Letters2021，32，9： | 2 |
| 10 | Synchrotron X-ray diffraction study of the phase transformations in titanium alloys显示文摘 | S Malinov W Sha Z Guo C.C Tang A.E Long | 2002 | Materials Characterization2002，，4： | 1 |
| 11 | Biotreatment of oily wastewater by rhamnolipids in aerated active sludge system显示文摘 | Hong-zi Zhang Xu-wei Long Ru-yi Sha Guo-liang Zhang Qin Meng | 2009 | Journal of Zhejiang University SCIENCE B2009，，11： | 1 |
| 12 | Modeling the occurrence and methods of reducing thermal deviations of upper furnace heating surfaces in a 1 000 MW dual circle tangential firing single furnace uhra-supercritical boiler显示文摘 | LIU Hui SHA Long XU Lianfei | 2014 | Numerical Heat Transfer Part A: Applications2014，66，7： | 1 |
| 13 | Research on the elliptic aerodynamic field in a 1 000 MW dual circle tangential firing single furnace ultra supercritical boiler 显示文摘 | SHA Long LIU Hui XU Lianfei | 2012 | Energy2012，46，1： | 1 |
| 14 | Two- step uhr',ffihration of rhanmolipids using PSU - g - PEG membrane 显示文摘 | LONG X W MENG Q SHA R Y | 2012 | Journal of Membrane Science2012，，： | 1 |
| 15 | Two-step ultrafiltration of rharnnolipids using PSU-g-PEG membrane显示文摘 | LONG X W MENG Q SHA R Y | 2012 | Journal of Membrane Science2012，409，： | 1 |
| 16 | Ultra-antifreeze,ultra-stretchable,transparent,and conductive hydrogel for multi-functional flexible electronics as strain sensor and triboelectric nanogenerator显示文摘Conductive hydrogels have become one of the most promising candidates for flexible electronics due to their excellent mechanical flexibility,durability of deformation,and good electrical conductivity.However,in real applications,severe environments occur frequently,such as extremely cold weather.General hydrogels always lack anti-freeze and anti-dehydration abilities.Consequently,the functions of electronic devices based on traditional hydrogels will quickly fail in extreme environments.Therefore,the development of environmentally robust hydrogels that can withstand extremely low temperatures,overcome dehydration,and ensure the stable operation of electronic devices has become increasingly important.Here,we report a kind of graphene oxide(GO)incorporated polyvinyl alcohol-polyacrylamide(PVA-PAAm)double network hydrogel(GPPDhydrogel)which shows excellent anti-freeze ability.The GPPD-hydrogel exhibits not only good flexibility and ultra-high stretchability up to 2,000%,but ensures a high sensitivity when used as the strain sensor at−50°C.More importantly,when serving as the electrode of a sandwich-structural triboelectric nanogenerator(TENG),the GPPD-hydrogel endows the TENG high and stable output performances even under−80°C.Besides,the GPPD-hydrogel is demonstrated long-lasting moisture retention over 100 days.The GPPD-hydrogel provides a reliable and promising candidate for the new generation of wearable electronics. | Xinhuan Dai Yong Long Bing Jiang Wenbin Guo Wei Sha Jiangwen Wang Zifeng Cong Jiwei Chen Bingjun Wang Weiguo Hu | 2022 | Nano Research2022，15，6： | 1 |
| 17 | Is hybrid surgery of the cervical spine a good balance between fusion and arthroplasty? Pilot results from a single surgeon series显示文摘 | Hwee Weng Dennis Hey Choon Chiet Hong Ai Sha Long Hwan Tak Hee | 2013 | European Spine Journal2013，，1： | 1 |
| 18 | Two-step ultrafiltration of rhamnolipids using PSU-g-PEG membrane显示文摘 | LONG Xu-wei MENG Qin SHA Ru-yi | 2012 | J Membr Sci2012，32，1： | 1 |
| 19 | Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways显示文摘BACKGROUND In traditional Chinese medicine(TCM),frankincense and myrrh are the main components of the antitumor drug Xihuang Pill.These compounds show anticancer activity in other biological systems.However,whether frankincense and/or myrrh can inhibit the occurrence of hepatocellular carcinoma(HCC)is unknown,and the potential molecular mechanism(s)has not yet been determined.AIM To predict and determine latent anti-HCC therapeutic targets and molecular mechanisms of frankincense and myrrh in vivo.METHODS In the present study,which was based on the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(http://gffzz390fd749913b458bh0kxpkvu6co6b65nn.ffgz.tsg.suse.edu.cn/tcmsp.php),Universal Protein database(http://gffzzc0d2db89b939488bh0kxpkvu6co6b65nn.ffgz.tsg.suse.edu.cn),GeneCards:The Human Gene Database(http://gffzza6b9c6ac78e94ba9h0kxpkvu6co6b65nn.ffgz.tsg.suse.edu.cn/)and Comparative Toxicogenomics Database(http://gffzz2b6478e0a40e4229h0kxpkvu6co6b65nn.ffgz.tsg.suse.edu.cn/),the efficacy of and mechanism by which frankincense and myrrh act as anti-HCC compounds were predicted.The core prediction targets were screened by molecular docking.In vivo,SMMC-7721 human liver cancer cells were transplanted as xenografts into nude mice to establish a subcutaneous tumor model,and two doses of frankincense plus myrrh or one dose of an EGFR inhibitor was administered to these mice continuously for 14 d.The tumors were collected and evaluated:the tumor volume and growth rate were gauged to evaluate tumor growth;hematoxylineosin staining was performed to estimate histopathological changes;immunofluorescence(IF)was performed to detect the expression of CD31,α-SMA and collagen IV;transmission electron microscopy(TEM)was conducted to observe the morphological structure of vascular cells;enzyme-linked immunosorbent assay(ELISA)was performed to measure the levels of secreted HIF-1αand TNF-α;reverse transcription-polymerase chain reaction(RT-qPCR)was performed to measure the mRNA expression of HIF-1α,TNF-α,VEGF and MMP-9;and Western blot(WB)was performed to determine the levels of proteins expressed in the EGFR-mediated PI3K/Akt and MAPK signaling pathways.RESULTS The results of the network pharmacology analysis showed that there were 35 active components in the frankincense and myrrh extracts targeting 151 key targets.The molecular docking analysis showed that both boswellic acid and stigmasterol showed strong affinity for the targets,with the greatest affinity for EGFR.Frankincense and myrrh treatment may play a role in the treatment of HCC by regulating hypoxia responses and vascular system-related pathological processes,such as cytokine-receptor binding,and pathways,such as those involving serine/threonine protein kinase complexes and MAPK,HIF-1 and ErbB signaling cascades.The animal experiment results were verified.First,we found that,through frankincense and/or myrrh treatment,the volume of subcutaneously transplanted HCC tumors was significantly reduced,and the pathological morphology was attenuated.Then,IF and TEM showed that frankincense and/or myrrh treatment reduced CD31 and collagen IV expression,increased the coverage of perivascular cells,tightened the connection between cells,and improved the shape of blood vessels.In addition,ELISA,RT-qPCR and WB analyses showed that frankincense and/or myrrh treatment inhibited the levels of hypoxia-inducible factors,inflammatory factors and angiogenesis-related factors,namely,HIF-1α,TNF-α,VEGF and MMP-9.Furthermore,mechanistic experiments illustrated that the effect of frankincense plus myrrh treatment was similar to that of an EGFR inhibitor with regard to controlling EGFR activation,thereby inhibiting the phosphorylation activity of its downstream targets:the PI3K/Akt and MAPK(ERK,p38 and JNK)pathways.CONCLUSION In summary,frankincense and myrrh treatment targets tumor blood vessels to exert anti-HCC effects via EGFR-activated PI3K/Akt and MAPK signaling pathways,highlighting the potential of this dual TCM compound as an anti-HCC candidate. | Piao Zheng Zhen Huang Dong-Chang Tong Qing Zhou Sha Tian Bo-Wei Chen Di-Min Ning Yin-Mei Guo Wen-Hao Zhu Yan Long Wei Xiao Zhe Deng Yi-Chen Lei Xue-Fei Tian | 2022 | World Journal of Gastrointestinal Oncology2022，14，2： | 1 |
| 20 | Decreased microRNA‐142‐3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus显示文摘 | Shu Ding Yunsheng Liang Ming Zhao Gongping Liang Hai Long Sha Zhao Yu Wang Heng Yin Peng Zhang Qing Zhang Qianjin Lu | 2012 | Arthritis & Rheumatism2012，，9： | 1 |
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