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| 1 | Micro-structural evolution and their effects on physical properties in different types of tectonically deformed coals显示文摘The macromolecular structure of tectonically deformed coals(TDC)may be determined by the deformation mechanisms of coal.Alterations of the macromolecular structure change the pore structure of TDC and thereby impact physical properties such as porosity and permeability.This study focuses on structure and properties of TDC from the Huaibei and Huainan coal mining areas of southern North China.Relationships between the macromolecular structure and the pore structure of TDC were analyzed using techniques such as X-ray diffraction,high-resolution transmission electron microcopy,and the low-temperature nitrogen adsorption.The results indicated that the directional stress condition can cause the arrangement of basic structural units(BSU)more serious and closer.And,the orientation is stronger in ductile deformed coal than in brittle deformed coal.Tectonic deformation directly influences the macromolecular structure of coal and consequently results in dynamic metamorphism.Because the size of BSU in brittle deformed coal increases more slowly than in ductile deformed coal,frictional heating and stress-chemistry of shearing areas might play a more important role,locally altering coal structure under stress,in brittle deformed coal.Strain energy is more significant in increasing the ductile deformation of coal.Furthermore,mesopores account for larger percentage of the nano-scale pore volume in brittle deformed coals,while mesopores volume in ductile deformed coal diminishes rapidly along with an increase in the proportion of micropores and sub-micropores.This research also approved that the deformations of macromolecular structures change nano-scale pore structures,which are very important for gas adsorption and pervasion space for gas.Therefore,the exploration and development potential of coal bed methane is promising for reservoirs that are subjected to a certain degree of brittle deformation(such as schistose structure coal,mortar structure coal and cataclastic structure coal).It also holds promise for TDC resulting from wrinkle structure coal of low ductile deformation and later superimposed by brittle deformation.Other kinds of TDC suffering from strong brittle-ductile and ductile deformation,such as scale structure coal and mylonitic structure coal,are difficult problems to resolve. | Yiwen Ju Kray Luxbacher Xiaoshi Li Guochang Wang Zhifeng Yan Mingming Wei Liye Yu | 2014 | International Journal of Coal Science & Technology2014，1，3： | 43 |
| 2 | Effects of Wen Dan Tang on insomnia-related anxiety and levels of the brain-gut peptide Ghrelin显示文摘Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medicine remedy Wen Dan Tang reduces insomnia-related anxiety, which may perhaps correspond to changes in the brain-gut axis. This suggests a possible relationship between Wen Dan Tang's pharmacological mechanism and the brain-gut axis. Based on this hypothesis, a sleep-deprived rat model was induced and Wen Dan Tang was administered using oral gavage during model establishment. Wen Dan Tang significantly reduced insomnia-related anxiety and prevented Ghrelin level decreases following sleep deprivation, especially in the hypothalamus. Increased expression of Ghrelin receptor mRNA in the hypothalamus was also observed, suggesting that reduced anxiety may be a result of Wen Dan Tang's regulation of Ghrelin-Ghrelin receptors. | Liye Wang Yuehan Song Feng Li Yan Liu Jie Ma Meng Mao Fengzhi Wu Ying Wu Sinai Li Binghe Guan Xiaolan Liu | 2014 | Neural Regeneration Research2014，9，2： | 16 |
| 3 | Analysis on the hourly spatiotemporal complementarities between China's solar and wind energy resources spreading in a wide area显示文摘China is rich in solar and wind energy resources,of which the proportion of China's power sources has been rapidly increasing.Such fluctuating and intermittent energy sources will bring significant challenges to the safe and stable operation power system.However,making use of the spatiotemporal complementarities between different renewable energy resources is a feasible way to level fluctuating power especially when they have a widely geographical dispersion.Based on the data provided by China Meteorological Administration(CMA),this research explores the spatiotemporal complementarities between wind and solar energy resources.This paper nondimensionalizes hourly wind speed and global solar radiation data and employs several indexes to compare the smoothing effect with various combining scenarios.The results show that combining wind and solar powers within a certain area can cause a fall of zero-power or very-full power hours.Besides,combining different resources improves 'smoothness' in power output when compared with that from each individual resource.However,under hourly time scale,when the dispersion of sites is large enough,the smoothing effect of combining the dispersed wind power is very close to the combination of those two different resources.Nevertheless,this complementary effect is much better than that of just combining solar energy resources. | LIU Yi XIAO LiYe WANG HaiFeng DAI ShaoTao QI ZhiPing | 2013 | Chinese Science Bulletin2013，58，7： | 14 |
| 4 | 地方性氟疾病与膳食营养水平关系研究显示文摘按统一研究设计和方法,对水氟浓度和营养状况不同的6个地区和煤氟含量不同的4个地区环境氟水平及1200多名40~60岁居民的膳食营养、总摄氟量、氟中毒等流行病学及生化指标进行了综合调查分析。结果显示:高氟和营养不足地区的氟中毒检出率显著高于总摄氟量相近而营养正常地区,证实人体营养状况特别是钙与蛋白质对氟化物吸收利用确有一定影响。调查发现:摄入过量氟可能使体内清除自由基的能力降低;在相同氟水平下,营养正常人群血浆过氧化物歧化酶和丙二醛均高于营养不足地区。但在各调查点。 | 孙淑庄 梁超轲 吉荣娣 曹静祥 杨世明 庞星火 林英琪 高玉真 陈志 王景占 张淑兰 黄文耀 LiY KatzBP BrizendineEJ8StookeyGK9 | 1996 | 卫生研究1996，25，5： | 12 |
| 5 | Recursive modeling and online identification of lithium-ion batteries for electric vehicle applications显示文摘For safe and reliable operation of lithium-ion batteries in electric vehicles,the real-time monitoring of their internal states is important.The purpose of our study is to find an easily implementable,online identification method for lithium-ion batteries in electric vehicles.In this article,we propose an equivalent circuit model structure.Based on the model structure we derive the recursive mathematical description.The recursive extended least square algorithm is introduced to estimate the model parameters online.The accuracy and robustness are validated through experiments and simulations.Real-road driving cycle experiment shows that the proposed online identification method can achieve acceptable accuracy with the maximum error of less than 5.52%.In addition,it is proved that the proposed method can also be used to estimate the real-time SOH and SOC of the batteries. | LI Yong WANG LiFang LIAO ChengLin WANG LiYe XU DongPin | 2014 | Science China(Technological Sciences)2014，57，2： | 10 |
| 6 | Application of high magnetic fields in advanced materials processing显示文摘Recently,steady magnetic fields avail-able from cryogen-free superconducting magnets open up new ways to process materials. In this paper,the main results obtained by using a high magnetic field to process several advanced materials are re-viewed. These processed objects primarily include superconducting,magnetic,metallic and nanome-ter-scaled materials. It has been found that a high magnetic field can effectively align grains when fab-ricating the magnetic and non-magnetic materials and make inclusions migrate in a molten metal. The mechanism is discussed from the theoretical view-point of magnetization energy. | MA Yanwei XIAO Liye YAN Luguang | 2006 | Chinese Science Bulletin2006，51，24： | 9 |
| 7 | Different contribution of SBP and DBP variability to vascular events in patients with stroke显示文摘Background High blood pressure variability(BPV)is a novel risk factor for cardiovascular disease.However,the heterogeneity of systolic blood pressure variability(SBPV)and diastolic blood pressure variability(DBPV)for different vascular events remains unclear.This study aims to investigate whether SBPV or DBPV has different contribution to vascular events in patients with acute ischaemic stroke(IS)or transient ischaemic attack(TIA).Methods Data from the BOSS(blood pressure and clinical outcome in TIA or IS)study were examined for vascular events at 3-month and 1-year follow-up.BPV was defined as the SD and coefficient of variation(CV)of day-to day measurements within 3 months after IS/TIA.Vascular events include cardiovascular events(myocardial infarction,unstable angina,cardiac death and congestive heart failure)and cerebrovascular events(ischaemic or haemorrhagic stroke).Logistic regression model was used to test the associations between BPV and vascular events.results Of 2325 patients with IS or TIA,103(4.43%)experienced a recurrent stroke and 64(2.75%)had cardiovascular events within 3 months.Day-to day SBPV was only associated with stroke recurrence(BPVSD:OR,1.72,95%CI 1.09 to 2.71;BPVCV:1.86,95%CI 1.19 to 2.92),but not cardiovascular events(BPVSD:1.67,95%CI 0.94 to 2.94;BPVCV:1.51,95%CI 0.86 to 2.64).However,DBPV seems to be related to both stroke(BPVSD:1.60,95%CI 1.02 to 2.49;BPVCV:1.53,95%CI 0.99 to 2.37)and cardiovascular events(BPVSD:2.48,95%CI 1.37 to 4.48;BPVCV:1.92,95%CI 1.09 to 3.36).Similar results were found at 1 year.Conclusions For patients with IS/TIA,stroke recurrence was associated with both SBPV and DBPV;however,cardiovascular events seem to be only related to DBPV. | Liye Dai Aichun Cheng Xiwa Hao Jie Xu Yingting Zuo Anxin Wang Xia Meng Hao Li Yilong Wang Xingquan Zhao Yongjun Wang | 2020 | Stroke & Vascular Neurology2020，5，2： | 6 |
| 8 | Science and prediction of monsoon heavy rainfall显示文摘With the increasing incidence of heavy rainfall events,particularly over the monsoon regions,the highly dense populations are more vulnerable[1].Research initiatives on observation,modeling,and prediction of monsoon heavy rainfall have been promoted actively by World Weather Research Programme's(WWRP)Working Group on Tropical Meteorology Research(WGTMR)of the World Meteorological Organization(WMO)since 2010.Series of monsoon-heavy-rainfall workshops were held in Beijing(2011),Petaling Jaya(2012),and New Delhi(2015)to benefit scientists worldwide and forecasters from the National Meteorological and Hydrological Services.An international Research and Development Project,namely,the Southern China Monsoon Rainfall Experiment(SCMREX)[2]was established in 2013 to coordinate field campaign experiments and to conduct scientific research on presummer(April-June)heavy rainfall processes in southern China. | Yali Luo Liye Li Richard HJohnson Chih-Pei Chang Lianshou Chen Wai-Kin Wong Jing Chen Kalli Furtado John LMcBride Ajit Tyagi Nanette Lomarda Thierry Lefort Esperanza O.Cayanan | 2019 | Science Bulletin2019，64，21： | 4 |
| 9 | Multidisciplinary co-design optimization of structural and control parameters for bucket wheel reclaimer显示文摘Bucket wheel reclaimer(BWR)is an extremely complex engineering machine that involves multiple disciplines,such as structure,dynamics,and electromechanics.The conventional design strategy,namely,sequential strategy,is structural design followed by control optimization.However,the global optimal solution is difficult to achieve because of the discoordination of structural and control parameters.The co-design strategy is explored to address the aforementioned problem by combining the structural and control system design based on simultaneous dynamic optimization approach.The radial basis function model is applied for the planning of the rotation speed considering the relationships of subsystems to minimize the energy consumption per volume.Co-design strategy is implemented to resolve the optimization problem,and numerical results are compared with those of sequential strategy.The dynamic response of the BWR is also analyzed with different optimization strategies to evaluate the advantages of the strategies.Results indicate that co-design strategy not only can reduce the energy consumption of the BWR but also can achieve a smaller vibration amplitude than the sequential strategy. | Yongliang YUAN Liye LV Shuo WANG Xueguan SONG | 2020 | Frontiers of Mechanical Engineering2020，15，3： | 4 |
| 10 | A moving boundary problem derived from heat and water transfer processes in frozen and thawed soils and its numerical simulation显示文摘The seasonal change in depths of the frozen and thawed soils within their active layer is reduced to a moving boundary problem,which describes the dynamics of the total ice content using an independent mass balance equation and treats the soil frost/thaw depths as moving(sharp)interfaces governed by some Stefan-type moving boundary conditions,and hence simultaneously describes the liquid water and solid ice states as well as the positions of the frost/thaw depths in soil.An adaptive mesh method for the moving boundary problem is adopted to solve the relevant equations and to determine frost/thaw depths,water content and temperature distribution.A series of sensitivity experiments by the numerical model under the periodic sinusoidal upper boundary condition for temperature are conducted to validate the model,and to investigate the effiects of the model soil thickness,ground surface temperature,annual amplitude of ground surface temperature and thermal conductivity on frost/thaw depths and soil temperature.The simulated frost/thaw depths by the model with a periodical change of the upper boundary condition have the same period as that of the upper boundary condition,which shows that it can simulate the frost/thaw depths reasonably for a periodical forcing. | XIE ZhengHui SONG LiYe FENG XiaoBing | 2008 | Science China Mathematics2008，51，8： | 4 |
| 11 | The effect of different deformation mechanisms on the chemical structure of anthracite coals显示文摘To study the effect of different deformation mechanisms on the chemical structure of anthracite coals and further understand the correlation between changed chemical structures and coal and gas outburst, ten groups of sub-high-temperature and sub-high-pressure deformation experiments were performed. All samples maintained primary structure, which were collected from the Qudi Mine in the southern Qinshui Basin of China. The samples were analyzed by ultimate analysis, Vitrinite Reflection(VR), Fourier Transform Infrared spectroscopy(FTIR), and Raman spectroscopy both before and after deformation experiments for contrasting. The results showed that the VR values of all samples after experiments were significantly higher than before experiments, which suggested that the metamorphism degree of anthracite coals was increased by deformation. The results also indicated that both temperature and strain rate had significant effects on the chemical structure of anthracite coals. At a high strain rate of 4×10?5 s?1, the deformation of the samples was mainly brittle in which the mechanical energy was transformed mainly into frictional energy. In this situation, all samples developed several distinct fractured surfaces and the change of chemical structures was not obvious. On the contrary, with the decrease of the strain rates, the ductile deformation was dominated and the mechanical energy was mainly transformed into strain energy, resulting in the accumulation of deformation energy confessed by increasing quantity of dislocation and creep in the coal's interior nucleus. The absorption in the aromatic ring groups increased; otherwise the absorption in the aliphatic structures and ether oxygen groups decreased rapidly. During these experiments, CO was collected from two experimental samples. The number of aromatic rings and the structure defects within the two generated gas samples increased and the degree of molecular structure orders decreased. | XU RongTing LI HuiJun HOU QuanLin LI XiaoShi YU LiYe | 2015 | Science China Earth Sciences2015，58，4： | 4 |
| 12 | Does exercise have a protective effect on cognitive function under hypoxia? A systematic review with meta-analysis显示文摘Objective:This study aimed to examine(1)the independent effects of hypoxia on cognitive function and(2)the effects of exercise on cognition while under hypoxia.Methods:Design:Systematic review with meta-analysis.Data sources:PubMed,Scopus,Web of Science,PsychInfo,and SPORTDiscus were searched.Eligibility criteria for selecting studies:randomized controlled trials and nonrandomized controlled studies that investigated the effects of chronic or acute exercise on cognition under hypoxia were considered(Aim 2),as were studies investigating the effects of hypoxia on cognition(Aim 1).Results:In total,18 studies met our inclusionary criteria for the systematic review,and 12 studies were meta-analyzed.Exposure to hypoxia impaired attentional ability(standardized mean difference(SMD)=-0.4),executive function(SMD=-0.18),and memory function(SMD=-0.26),but not information processing(SMD=0.27).Aggregated results indicated that performing exercise under a hypoxia setting had a significant effect on cognitive improvement(SMD=0.3,95%confidence interval:0.14-0.45,I^2=54%,p<0.001).Various characteristics(e.g.,age,cognitive task type,exercise type,exercise intensity,training type,and hypoxia level)moderated the effects of hypoxia and exercise on cognitive function.Conclusion:Exercise during exposure to hypoxia improves cognitive function.This association appears to be moderated by individual and exercise/hypoxia-related characteristics. | Myungjin Jung Liye Zou Jane Jie Yu Seungho Ryu Zhaowei Kong Lin Yang Minsoo Kang Jingyuan Lin Hong Li Lee Smith Paul D.Loprinzi | 2020 | Journal of Sport and Health Science2020，9，6： | 3 |
| 13 | TOOR: A Novel Product Title Optimization Method Based on Online Reviews in E-commerce显示文摘联机产品的标题在吸引消费者并且在电子商务支持产品出售起一个重要作用。然而,当前的联机产品标题仅仅盖住基本特征并且不能确切反映消费者的偏爱。处理这个问题,这研究基于联机评论的分析建议了一个联机标题优化方法,它被称为 TOOR (标题优化基于联机评论) 。在这研究,我们分析了并且比较从消费者的观点从联机产品标题和联机评论提取并且使用了从评论提取到标题优化的特征的产品特征。以便验证建议方法的有效性,二个实验在这篇论文被进行,作为数据资源作为实验样品和 Taobao.com 选择四典型 smartphones。试验性的结果显示从联机评论提取的特征能更好反映消费者担心,并且标题由 TOOR 方法优化了是更多的投消费者所好并且有更高的点按彻底地率。 | Liye Wang Jin Zhang Wei Yan | 2015 | Frontiers of Business Research in China2015，9，4： | 3 |
| 14 | Modifed Multifdelity Surrogate Model Based on Radial Basis Function with Adaptive Scale Factor显示文摘Multifdelity surrogates(MFSs)replace computationally intensive models by synergistically combining information from diferent fdelity data with a signifcant improvement in modeling efciency.In this paper,a modifed MFS(MMFS)model based on a radial basis function(RBF)is proposed,in which two fdelities of information can be analyzed by adaptively obtaining the scale factor.In the MMFS,an RBF was employed to establish the low-fdelity model.The correlation matrix of the high-fdelity samples and corresponding low-fdelity responses were integrated into an expansion matrix to determine the scaling function parameters.The shape parameters of the basis function were optimized by minimizing the leave-one-out cross-validation error of the high-fdelity sample points.The performance of the MMFS was compared with those of other MFS models(MFS-RBF and cooperative RBF)and single-fdelity RBF using four benchmark test functions,by which the impacts of diferent high-fdelity sample sizes on the prediction accuracy were also analyzed.The sensitivity of the MMFS model to the randomness of the design of experiments(DoE)was investigated by repeating sampling plans with 20 diferent DoEs.Stress analysis of the steel plate is presented to highlight the prediction ability of the proposed MMFS model.This research proposes a new multifdelity modeling method that can fully use two fdelity sample sets,rapidly calculate model parameters,and exhibit good prediction accuracy and robustness. | Yin Liu Shuo Wang Qi Zhou Liye Lv Wei Sun Xueguan Song | 2022 | Chinese Journal of Mechanical Engineering2022，35，4： | 3 |
| 15 | Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy显示文摘 | Yifang Han Hui Cai Liye Ma Yibo Ding Xiaojie Tan Wenjun Chang Wei Guan Yan Liu Qiuxia Shen Yongwei Yu Hongwei Zhang Guangwen Cao | 2013 | Cancer2013，，19： | 2 |
| 16 | Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta)显示文摘 | Huimin Qi Liye Huang Xiaolei Liu Dongmei Liu Quanbin Zhang Shunmei Liu | 2011 | Carbohydrate Polymers2011，，2： | 2 |
| 17 | Safety,tolerability,and pharmacokinetics of BAT8001 in patients with HER2-positive breast cancer:An open-label,dose-escalation,phase I study显示文摘Background:The introductions of anti-human epidermal growth factor receptor-2(HER2)agents have significantly improved the treatment outcome of patients with HER2-positive breast cancer.BAT8001 is a novel antibodydrug conjugate targeting human epidermal growth factor receptor-2(HER2)-expressing cells composed of a trastuzumab biosimilar linked to the drug-linker Batansine.This dose-escalation,phase I study was designed to assess the safety,tolerability,pharmacokinetics,and preliminary anti-tumor activity of BAT8001 in patients with HER2-positive locally advanced or metastatic breast cancer.Methods:This trial was conducted in subjects with histologically confirmed HER2-positive breast cancer(having evaluable lesions and an Eastern Cooperative Oncology Group performance status of 0 or 1)using a 3+3 design of escalating BAT8001 doses.Patients received BAT8001 intravenously in a 21-day cycle,with dose escalation in 5 cohorts:1.2,2.4,3.6,4.8,and 6.0 mg/kg.The primary objective was to evaluate the safety and tolerability of BAT8001.Preliminary activity of BAT8001 was also assessed as a secondary objective.Results:Between March 2017 to May 2018,29 HER2-positive breast cancer patients were enrolled.The observed dose-limiting toxicities were grade 4 thrombocytopenia and grade 3 elevated transaminase.The maximum tolerated dose was determined to be 3.6 mg/kg.Grade 3 or greater adverse events(AEs)occurred in 14(48.3%)of 29 patients,including thrombocytopenia in 12(41.4%)patients,aspartate aminotransferase increased in 4(13.8%)patients,γ-glutamyl transferase increased in 2(6.9%)patients,alanine aminotransferase increased in 2(6.9%)patients,diarrhea in 2(6.9%)patients.Objective response was observed in 12(41.4%,95%confidence interval[CI]=23.5%-61.1%)and disease control(including patients achieving objective response and stable disease)was observed in 24(82.8%,95%CI=64.2%-94.2%)patients.Conclusions:BAT8001 demonstrated favorable safety profiles,with promising anti-tumor activity in patients with HER2-positive locally advanced or metastatic breast cancer.BAT8001 has the potential to provide a new therapeutic option in patients with metastatic HER2-positive breast cancer. | Ruoxi Hong Wen Xia Liye Wang Kaping Lee Qianyi Lu Kuikui Jiang Shengfeng Li Jinquan Yu Jin Wei Weijia Tang Danyang Zhou Xin An Jiajia Huang Cong Xue Xiwen Bi Yanxia Shi Zhongyu Yuan Fei Xu Shusen Wang | 2021 | Cancer Communications2021，41，2： | 2 |
| 18 | INDIRECT ACCELERATED ADAPTIVE FUZZY CONTROLLER显示文摘According to a type of normal nonlinear system,an indirect adaptive fuzzy (IAF) controller has been applied to those systems where no accurate mathematical models of the systems under control are available. To satisfy with system performance,an indirect accelerated adaptive fuzzy (IAAF) controller is proposed,and its general form is presented. The general form IAAF controller ensures necessary control criteria and system's global stability using Lyapunov Theorem. It has been proved that the close-loop system error converges to a small neighborhood of equilibrium point. The optimal IAAF controller is derived to guarantee the process's shortest settling time. Simulation results indicate the IAAF controller make the system more stable,accurate,and fast. | ZHU Liye FANG Yuan ZHANG Weidong | 2008 | Chinese Journal of Mechanical Engineering2008，21，1： | 2 |
| 19 | A model-based driving cycle test procedure of electric vehicle batteries显示文摘The battery test methods are the key issues to investigate the energy-storage characteristics and dynamic characteristics of electric vehicle(EV) batteries.In this paper,the research advances of existing battery test methods as well as driving cycles are reviewed.An electric vehicle model that consists of EV dynamics model,battery model and electric motor model is built.The dynamic characteristics of the battery in frequency domain are analyzed.Based on the EV model and the frequency domain characteristics of the battery,a driving cycle test procedure of EV battery is proposed.The battery test procedure is able to reflect the real-world characteristics of EV batteries,and can be used as a universal EV battery test method. | 李勇 Wang Lifang Liao Chenglin Wang Liye | 2014 | High Technology Letters2014，20，3： | 2 |
| 20 | Methods Used to Study Bacterial Diversity in the Marine Environment around Qingdao显示文摘Pollution has a considerable effect on biological communities, in terms of size and diversity of the populations. Yet, the precise consequences of human activity on microbial communities in the marine environment are poorly understood. Therefore, in an ongoing collaborative research programme between Heriot-Watt University and the Ocean University of Qingdao, bacteria were isolated in 1999 and 2000 from marine sediment, seawater, seaweed, fish and shellfish, taken from locations in Shandong Province adjacent to Qingdao. Sampling locations were comprised of industrial and aquacultural sites and a clean, control site. In order to analyse microbial diversity, a polyphasic approach was adopted for characterisation of these isolates, specifically through examination of key phenotypic traits, i.e. using Biolog GN MicroPlate TM profiles, bacterial whole cell protein profiles and 16S and 23S rRNA gene sequences. These techniques yielded complex taxonomic data, which were subjected to statistical and cluster analyses. The application of these methods to studies of microbial communities is discussed. | RobertsonP.A.W MaclnnesJ SparaganoO.A.E PurdomI LIY YUD.H DUZ.J XUH.S AustinB | 2002 | Journal of Ocean University of Qingdao2002，1，2： | 2 |
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