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| 1 | Conservation and Diversification of the SHR-SCR- SCL23 Regulatory Network in the Development of the Functional Endodermis in Arabidopsis Shoots显示文摘部分地, Arabidopsis thaliana 根的功能的内皮的开发被 GRAS 抄写因素控制,也就是短根(SHR ) ,衣衫褴褛的人(SCR ) ,并且像衣衫褴褛的人 23 (SCL23 ) 。最近, SHR-SCR-SCL23 规章的模块为内皮的说明也是必要的,这被显示出(作为捆鞘知道) 在叶子。与在根对 SHR-SCR-SCL23 规章的网络的角色被知道的相比,不过, SHR, SCR,和 SCL23 的分子的相互作用更不在射击被理解。这里,我们证明 SHR 与 SCL23 形成蛋白质建筑群在射击调整 SCL23 的抄写,类似于 SCR 的规定模式表示。我们的结果显示 SHR 充当主人管理者直接激活 SCR 和 SCL23 的表示。在 SHR-SCR-SCL23 网络,我们发现了一以前 SCL23 调制 SHR 的否定反馈循环铺平的 uncharacterized。通过分子、基因、生理、词法的分析,我们也表明 SHR-SCR-SCL23 模块在内皮的形成起一个关键作用(作为淀粉鞘知道) 在胚轴。一起拿,我们的结果在根和射击在内皮开发提供新卓见进 SHR-SCR-SCL23 网络的规章的角色。 | Eun Kyung Yoon Souvik Dhar Mi-Hyun Lee Jae Hyo Song Shin Ae Lee Gyuree Kim Sejeong Jang Ji Won Choi Jeong-Eun Choe Jeong Hoe Kim Myeong Min Lee Jun Lim | 2016 | Molecular Plant2016，9，8： | 6 |
| 2 | Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue显示文摘在多细胞的有机体,控制预定和不对称的细胞部门(ACD ) 的程度为正确 patterning 是关键的。在在 Arabidopsis thaliana 的 embryonic 以后根开发期间,地面织物(GT ) 成熟包含内皮的另外的 ACD,它产生二不同纸巾:内皮(内部) 并且中间的外皮(外部) 。这被报导了 abscisic 酸(骆驼毛的织物) 和赤霉素(GA ) 小径涉及中间的外皮(MC ) 形成。然而,在 GT 成熟期间位于在骆驼毛的织物和 GA 之间的相互作用下面的分子的机制仍然保持大部分未知。通过 transcriptome 分析,我们识别了一以前 uncharacterized C 2 H 2-type 锌手指基因,其表情被 GA 和骆驼毛的织物调整,因此命名的 GAZ (GA- 和骆驼毛的织物应答的锌手指) 。幼苗宫外地 overexpressing GAZ (GAZ 公牛) 在 MC 形成期间对骆驼毛的织物和 GA 敏感,而 GAZ-SRDX 和 RNAi 幼苗显示了相反的显型。另外,我们的结果显示 GAZ 涉及骆驼毛的织物和 GA 动态平衡的 transcriptional 规定。与那件骆驼毛的织物和 GA 协调控制预定 MC 形成的以前的研究一致,我们也证实了在骆驼毛的织物和 GA 之间的唯一的相互影响并且识别了在 Arabidopsis 根的 GT 成熟期间衔接二条荷尔蒙小径的因素和规章的网络。 | Shin Ae Lee Sejeong Jang Eun Kyung Yoon Jung-Ok Heo Kwang Suk Chang Ji Won Choi Souvik Dhar Gyuree Kim Jeong-Eun Choe Jae Bok Heo Chian Kwon Jae-Heung Ko Yong-Sic Hwang Jun Lim | 2016 | Molecular Plant2016，9，6： | 2 |
| 3 | Reappraisal of serum alpha‐foetoprotein as a surveillance test for hepatocellular carcinoma during entecavir treatment显示文摘 | Gi‐Ae Kim Chang Hyeon Seock Jang Won Park Jihyun An Kwang‐Sun Lee Jee Eun Yang Young‐Suk Lim Kang Mo Kim Ju Hyun Shim Danbi Lee Han Chu Lee | 2015 | Liver Int2015，，1： | 2 |
| 4 | Weekly docetaxel and gemcitabine in previously treated metastatic esophageal squamous cell carcinoma显示文摘AIM: To assess the efficacy and safety of weekly docetaxel plus a fixed-dose rate(FDR) of gemcitabine in metastatic esophageal squamous cell carcinoma(SCC).METHODS: A multi-center, open-label, prospective phase Ⅱ study was designed.Thirty-three esophageal SCC patients with documented progression after fluoropyrimidine/platinum-based first-line chemotherapy were enrolled and treated with docetaxel 35 mg/m2 and gemcitabine 1000 mg/m2 iv at a FDR(10 mg/m2 per minute) on days 1 and 8.Treatment was repeatedevery twenty-one days until disease progression, unacceptable toxicity, or consent withdrawal.The primary endpoint was response rate(RR), and secondary endpoints were safety, progression-free survival(PFS) and overall survival(OS).RESULTS: Combination of weekly docetaxel and FDR gemcitabine was well tolerated: the most common treatment-related adverse events were anemia(97%), fatigue(64%) and neutropenia(55%).One patient with multiple lung and lymph node metastases died of respiratory failure after receiving four cycles of chemotherapy, and the possibility of drug-induced pneumonitis could not be completely excluded.Disease control(objective response plus stable disease) in the ITT population was achieved in 88% of patients, and the overall RR was 30%(95%CI: 15%-46%).The median PFS and OS were 4.0(95%CI: 3.4-4.6) and 8.8 mo(95%CI: 7.8-9.8 mo), respectively.CONCLUSION: A combination of weekly docetaxel and FDR gemcitabine showed promising antitumor activity and tolerability in previously treated, metastatic esophageal SCC. | Min-Young Lee Ki Sun Jung Hae Su Kim Ji Yun Lee Sung Hee Lim Moonjin Kim Hyun Ae Jung Sung Min Kim Jong Mu Sun Myung-Ju Ahn Jeeyun Lee Se Hoon Park Seong Yoon Yi In Gyu Hwang Sang-Cheol Lee Hee Kyung Ahn Do Hyoung Lim Soon Il Lee Keon Woo Park | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 5 | The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes:a placebo-controlled randomized clinical trial 显示文摘 | Caballero AE Saouaf R Lim SC | 2003 | Metabolism2003，52，2： | 1 |
| 6 | Preparation and Characterization of Composites Based on Polylactic Acid and Beeswax with Improved Water Vapor Barrier Properties显示文摘 | Jung Hoon Lim Jeong Ae Kim Jung A Ko Hyun Jin Park | 2015 | Journal of Food Science2015，，： | 1 |
| 7 | Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Therapy Promotes Functional Recovery of Contused Rat Spinal Cord through Enhancement of Endogenous Cell Proliferation and Oligogenesis显示文摘 | Sang In Park Jung Yeon Lim Chang Hyun Jeong Seong Muk Kim Jin Ae Jun Sin-Soo Jeun Won Il Oh Ken-ichi Isobe | 2012 | Journal of Biomedicine and Biotechnology2012，，： | 1 |
| 8 | p53 Controls Autoimmune Arthritis via STAT‐Mediated Regulation of the Th17 Cell/Treg Cell Balance in Mice显示文摘 | Jin‐Sil Park Mi‐Ae Lim Mi‐La Cho Jun‐Geol Ryu Young‐Mee Moon Joo‐Yeon Jhun Jae‐Kyeong Byun Eun‐Kyung Kim Sue‐Yun Hwang Ji Hyeon Ju Seung‐Ki Kwok Ho‐Youn Kim | 2013 | Arthritis & Rheumatism2013，，4： | 1 |
| 9 | Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin显示文摘 | Lim do Y Jeong Y Tyner AE | 2007 | Am J Physiol Gastrointest Liver Physiol2007，292，1： | 1 |
| 10 | Water removal characteristics of proton exchange membrane fuel cells using a dry gas purging method显示文摘 | Sang-Yeop Lee Sang-Uk Kim Hyoung-Juhn Kim Jong Hyun Jang In-Hwan Oh Eun Ae Cho Seong-Ahn Hong Jaejun Ko Tae-Won Lim Kwan-Young Lee Tae-Hoon Lim | 2008 | Journal of Power Sources2008，，2： | 1 |
| 11 | The nonmotor symptoms of Parkinson's disease--an overview显示文摘 | Lim SY Lang AE | 2010 | Mov Disord2010，251，： | 1 |
| 12 | Resilience to urban poverty: theoretical and empirical considerations for pop- ulation health 显示文摘 | Sanders AE Lim S Sohn W | 2008 | Am J Public Health2008，98，6： | 1 |
| 13 | The effects of troglitazone,an insulin-sensitizing agent,on the endothelial function in early and late type 2 diabetes:a placebo-controlled randomized clinical trial显示文摘 | Caballero AE Saouaf R Lim SC | 2003 | Metabolism2003，52，2： | 1 |
| 14 | The effects of troglitszone,an insulin sensitizing agent,on the endothelial function in early and late type 2 dibetes:a placebo-controlled randomized clinical trial显示文摘 | Caballero AE SaouafR Lim SC | 2003 | Metabolism2003，52，2： | 1 |
| 15 | Optimizing the osteogenic potential of adult stem cells for skeletal regeneration显示文摘 | Lim JY Loisel e AE Lee JS | | 0，，11： | 1 |
| 16 | Impact of oral disease on quality of life in the US and Australian populations显示文摘 | Sanders AE Slade GD Lim S | 2009 | Community Dent Oral Epidemiol2009，37，2： | 1 |
| 17 | Soluble intercellular adhesion molecule,vascular cell adhesion molecule,and impaired microvascular reactivity are earl markers of vasculopathy in type 2 diabetic individuals without microalbuminuria显示文摘 | Lim SC Caballero AE Smakowski P | 1999 | Diabetes Care1999，22，： | 1 |
| 18 | Impact of oral disease on quality of life in the US and Australian populations 显示文摘 | Sanders AE Slade GD Lim S | 2009 | Community Dent Oral Epidemiol2009，37，2： | 1 |
| 19 | White light-emitting diodes of GaN-based Sr2SiO4:Eu and the luminescent properties显示文摘 | Joung Kyu Park Mi Ae Lim Chang Hae Kim | 2003 | Appl Phys Lett2003，82，5： | 1 |
| 20 | Soluble intercellular adhesion molecule, vascular cell adhesion molecule, and impaired microvascular reactivity are early markers of vasculopathy in type 2 diabetic individuals without microalbuminuria 显示文摘 | Lim SC Caballero AE Smakowski P | 1999 | Diabetes Care1999，22，11： | 1 |
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