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| 1 | Analysis of Pathological data of renal biopsy at one single center in China from 1987 to 2012显示文摘 | Zhang Xueguang Liu Shuwen Tang Li Wu Jie Chen Pu Yin Zhong Li Minxia Xie Yuansheng Cai Guangyan Wei Ribao Qiu Qiang Wang Yuanda Shi Suozhu Chen Xiangmei | 2014 | Chinese Medical Journal2014，，9： | 30 |
| 2 | Investigation of Amorphization of Nb-Si Alloys by Mechanical Alloying显示文摘Amorphous Nb_(62.5)Si_(37.5) and Nb_(75)Si_(25) alloys were produced from mixtures of elemental Nb and Si powders by mechanical alloying(MA).The structural changes of mechanically alloyed powders were monitored by x-ray diffraction.It was found that NbSi_(2),intermetallic compound was formed in the initial stage of MA of or Nb_(62.5)Si_(37.5) or Nb_(75)Si_(25) powders.With continued milling,the mixtures of intermetallic NbSi_(2) and elemental Nb transformed into amorphous Nb-Si alloys(Nb_(62.5)Si_(37.5) or Nb_(75)Si_(25)).The slow interdiffusion of Nb and Si and the slower diffusion of silicon atoms to niobium matrix than that of niobium atoms to silicon matrix were suggested to be responsible for the formation of intermetallic NbSi_(2).The amorphization of 3NbSi_(2)+7Nb mixtures(or NbSi_(2)+5Nb mixtures)is believed to be controlled by material transfer,which moves composition of line intermetallic NbSi2 off stoichiometry,and causes the matrix of elemental Nb deformed. | LI Bing MA Xueming LIU Lin QI Zhenzhong DONG Yuanda | 1994 | Chinese Physics Letters1994，11，11： | 4 |
| 3 | Perovskite-transition metal dichalcogenides heterostructures: recent advances and future perspectives显示文摘Transition metal dichalcogenides(TMDs)and perovskites are among the most attractive and widely investigated semiconductors in the recent decade.They are promising materials for various applications,such as photodetection,solar energy harvesting,light emission,and many others.Combining these materials to form heterostructures can enrich the already fascinating properties and bring up new phenomena and opportunities.Work in this field is growing rapidly in both fundamental studies and device applications.Here,we review the recent findings in the perovskite-TMD heterostructures and give our perspectives on the future development of this promising field.The fundamental properties of the perovskites,TMDs,and their heterostructures are discussed first,followed by a summary of the synthesis methods of the perovskites and TMDs and the approaches to obtain high-quality interfaces.Particular attention is paid to the TMD-perovskite heterostructures that have been applied in solar cells and photodetectors with notable performance improvement.Finally through our analysis,we propose an outline on further fundamental studies and the promising applications of perovskite-TMD heterostructures. | Ahmed Elbanna Ksenia Chaykun Yulia Lekina Yuanda Liu Benny Febriansyah Shuzhou Li Jisheng Pan Ze Xiang Shen Jinghua Teng | 2022 | Opto-Electronic Science2022，1，8： | 2 |
| 4 | Interference at the single-photon level based on silica photonics robust against channel disturbance显示文摘Quantum key distribution(QKD) provides a solution for communication of unconditional security. However,the quantum channel disturbance in the field severely increases the quantum bit-error rate, degrading the performance of a QKD system. Here we present a setup comprising silica planar light wave circuits(PLCs), which is robust against the channel polarization disturbance. Our PLCs are based on the asymmetric Mach–Zehnder interferometer(AMZI), integrated with a tunable power splitter and thermo-optic phase modulators. The polarization characteristics of the AMZI PLC are investigated by a novel pulse self-interfering method to determine the operation temperature of implementing polarization insensitivity. Over a 20 km fiber channel with 30 Hz polarization scrambling, our time-bin phase-encoding QKD setup is characterized with an interference fringe visibility of 98.72%. The extinction ratio for the phase states is kept between 18 and 21 d B for 6 h without active phase correction. | XIAO LI MEIZHEN REN JIASHUN ZHANG LIANGLIANG WANG WEI CHEN YUE WANG XIAOJIE YIN YUANDA WU JUNMING AN | 2021 | Photonics Research2021，9，2： | 2 |
| 5 | Internet-oriented new word identification 显示文摘 | LI Dun CAO Fuyuan CAO Yuanda | 2007 | Journal of Computational Informa- tion System2007，3，6： | 1 |
| 6 | Doctors’Dilemma in Auspicious Pulse Diagnosis Represented in Ming-Qing Fiction显示文摘Auspicious pulse diagnosis/pregnancy diagnosis in traditional Chinese medicine involves such issues as medical skills,narrative skills,family decency,and ethics.It is an excellent case for the exploration of ethical dilemmas in traditional Chinese medical practice.The early classical medical texts such as Su Wen(Basic Questions)and Ling Shu Jing(Spiritual Pivot Canon)provide a principle-based ethical guide for doctor-patient communication,while popular fiction such as Hong Lou Meng(A Dream of Red Mansions),Yu Mu Xing Xin Bian(Stories:Entertain to Enlighten),and Feng Yue Meng(Courtesans and Opium)in the Ming and Qing dynasties present literary examples for solving ethical dilemmas.This article will analyze these texts from three perspectives.First,the doctors in the text were subject to gender order and other delicate etiquette and customs,therefore were unable to make the diagnosis without embarrassing the patients and jeopardizing family decency.Second,the narrator tends to attribute pregnancy misdiagnosis to three reasons:incomplete patient information,doctors’poor narrative competence,and doctors’corrupted medical ethics.Finally,the Ming-Qing fiction proposes three methods to solve this moral dilemma:clear pulse reading,tactful speech,and taboo challenging.This discussion of moral dilemmas in pregnancy diagnosis in traditional Chinese medical practice can be used as a reference for the localization of narrative medicine. | LI Yuanda MAO Xu | 2023 | Chinese Medicine and Culture2023，6，2： | 1 |
| 7 | White Electroluminescence with Simultaneous Three-Color Emission from a Four-Armed Star-Shaped Single-Polymer System显示文摘有4,7二度的一个四手臂的塑造星的单个聚合物的系统(5-(4-( 9H-carbazol-9-yl )苯基) -4-hexylthiophen-2-yl)benzo[c][1,2,5]thiadiazole ( FTBT )作为一个红放射性的核心, polyfluorene ( PF )作为绿放射性的掺杂物作为蓝放射性的手臂和 1,3-benzo thiadiazole ( BT )被设计并且综合,在里面哪个红,绿,并且蓝色(红绿蓝)排放平衡能被小心地调整 FTBT 和 BT 的做的集中完成。一台典型 single-emissive-layer 设备(ITO/PEDOT : PSS/polymer/TPBI/LiF/Al ) 被学习并且讨论,与 1.59 cd·A −1 和 CIE 的发光效率(LE ) 认识到纯、稳定的白排出物协调(0.31, 0.34 ) 。设备的 high-color-quality 白人 electroluminescence 能主要从蓝 PF 手臂被归因于压制的分子间的相互作用,和部分精力转移到红、绿的掺杂物。 | Yuanda Jiu Jianyun Wang Chengfang Liu Wenyong Lai Lingling Zhao Xiangchun Li Yi Jiang Weidong Xu Xinwen Zhang Wei Huang | 2015 | Chinese Journal of Chemistry2015，33，8： | 1 |
| 8 | Autotaxin: A protein with two faces显示文摘 | Mousumi Tania Md. Asaduzzaman Khan Huaiyuan Zhang Jinhua Li Yuanda Song | 2010 | Biochemical and Biophysical Research Communications2010，，4： | 1 |
| 9 | Recapitulation of growth factor-enriched microenvironment via BMP receptor activating hydrogel显示文摘Exposure to a growth factor abundant milieu has remarkable regenerative and rejuvenating effects on organ diseases,tissue damage,and regeneration,including skeletal system defects and bone regeneration.Although the introduction of candidate growth factors into relevant fields has been reported,their regenerative effects remain unsatisfactory,mainly because of the experimental challenges with limited types of growth factors,elusive dosage adjustment,and asynchronous stem cell activation with cytokine secretion.Here,an innovative hydrogel recapitulating a growth factor-enriched microenvironment(GEM)for regenerative advantage,is reported.This sulfated hydrogel includes bone morphogenetic protein-2(BMP-2),an essential growth factor in osteogenesis,to direct mesenchymal stem cell(MSC)differentiation,stimulate cell proliferation,and improve bone formation.The semi-synthetic hydrogel,sulfonated gelatin(S-Gelatin),can amplify BMP-2 signaling in mouse MSCs by enhancing the binding between BMP-2 and BMP-2 type II receptors(BMPR2),which are located on MSC nuclei and activated by the hydrogel.Importantly,the dramatically improved cytokine secretion of MSCs throughout regeneration confirms the growth factor-acquiring potential of S-Gelatin/rhBMP-2 hydrogel,leading to the vascularization enhancement.These findings provide a new strategy to achieve an in situ GEM and accelerated bone regeneration by amplifying the regenerative capacity of rhBMP-2 and capturing endogenous growth factors. | Qinghao Zhang Yuanda Liu Jie Li Jing Wang Changsheng Liu | 2023 | Bioactive Materials2023，，2： | 0 |
| 10 | Influence of Milling Conditions on the Mechanical Alloying of Fe-B Powders显示文摘Amorphous and nanostructural Fe-B alloys made by mechanical alloying of elemental Fe and amorphous B powders have been studied using X-ray diffraction, differential scanning calorimetry and Mossbauer spectroscopy. It has been shown that the milling conditions have a strong effect on the alloying. The single phase amorphous alloy, which is limited at nominal composition of Fe60B40, has been produced only by milling in Ar atmosphere and in other composition range the mixture of nanostructure Fe-like phase and Fe2B compound with a little amorphous phase are obtained. While by milling in air atmosphere the introduction of oxygen in air may suppress the formation of amorphous phase, thus the compounds Fe2B may be synthesized with no trace of amorphous phase. The crystallization temperatures of amorphous phase in the resultant products are higher than those of a single amorphous alloy Fe60B40, and hardly independent of the milling conditions and the composition. In addition, it is revealed that detectable B content in the final products is lower than the nominal composition of all the initial samples, which indicates that some B atoms may be located in the disordered interfacial regions of the nanostructural alloyed mixtures. | Yang, Yuanzheng Li, Qiaoshen Zhu, Youlan Ma, Xueming Dong, Yuanda | 1999 | Journal of Materials Science & Technology1999，15，2： | 0 |
| 11 | Thermal stability and glass-forming ability of Y-Ce-Co-Al bulk metallic glasses显示文摘The thermal stability and glass-forming ability of Y56-xCexCo20Al24 (x=15, 20, 25, 28, 38, 41, 44) bulk metallic glasses with a diameter of 5 mm were investigated by differential scanning calorimetry and X-ray diffraction. The results show that the thermal stability of the alloys decreases with the addition of Ce. It has the best glass-forming ability when x=25, whose calculated values can reach about 30 mm in diameter. The effect of Ce element could be explained on the view of Miedema’s theory and elec- tronegativity difference of amorphous alloys. | Jun Li, Xueshan Xiao, and Yuanda Dong Institute of Materials, Shanghai University, Shanghai 200072, China | 2007 | International Journal of Minerals,Metallurgy and Materials2007，15，S1： | 0 |
| 12 | A Mssbauer Study on the Mechanically Alloyed Cu-Sn Alloys显示文摘Nanocrystalline E and η electron compounds and supersaturated solid solution of the Cu-Sn system have been prepared by mechanical alloying of elemental Cu and Sn powders. The atomie alloying and microstructure of the resultant alloys have been investigated by XRD, DSC and 119Sn Mossbauer spectroscopy. A little amount of SnO2 was detected by Mossbauer spectroscopy, although no trace of diffiaction peaks occurred in the XRD pattern. Thus the spectra for all the milled samples should be fitted using two quadrupole-splitting doublets: one corre sponding to SnO2, the other corresponding to the resultant alloys. The composition dependence of the hyperfine parameters has been eXtensively discussed and explained well with respect to oxidation, sudece effect resulting from grain refinement, coordination environment asymmetry and distortion caused or/and induced by mechanical alloying. | Yuanzheng YANG Youlan ZHU and Qiaoshen LI(Dept. of Materials Science and Engineering, Guangdong University of Technology, Guangzhou 510090, China)Xueming MA and Yuanda DONG(Dept. of Materials Science and Engineering, Shanghai University, Shanghai 200072, | 1998 | Journal of Materials Science & Technology1998，14，6： | 0 |
| 13 | Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy显示文摘Despite the remarkable success of immune checkpoint inhibitors(ICIs),primary resistance to ICIs causes only subsets of patients to achieve durable responses due to the complex tumor microenvironment(TME).Oncolytic viruses(OVs)can overcome the immunosuppressive TME and promote systemic antitumor immunity in hosts.Engineered OVs armed with ICIs would likely have improved effectiveness as a cancer therapy.According to the diverse immune cell landscapes among different types of tumors,we rationally and precisely generated three recombinant oncolytic adenoviruses(OAds):OAd-SIRPα-Fc,OAd-Siglec10-Fc and OAd-TIGIT-Fc.These viruses were designed to locally deliver SIRPα-Fc,Siglec10-Fc or TIGIT-Fc fusion proteins recognizing CD47,CD24 or CD155,respectively,in the TME to achieve enhanced antitumor effects.Our results suggested that OAd-SIRPα-Fc and OAd-Siglec10-Fc both showed outstanding efficacy in tumor suppression of macrophage-dominated tumors,while OAd-TIGIT-Fc showed the best antitumor immunity in CD8+T-cell-dominated tumors.Importantly,the recombinant OAds activated an inflammatory immune response and generated long-term antitumor memory.In addition,the combination of OAd-Siglec10-Fc with anti-PD-1 significantly enhanced the antitumor effect in a 4T1 tumor model by remodeling the TME.In summary,rationally designed OAds expressing ICIs tailored to the immune cell landscape in the TME can precisely achieve tumor-specific immunotherapy of cancer. | Daoyuan Xie Yaomei Tian Die Hu Yuanda Wang Yuling Yang Bailing Zhou Rui Zhang Zhixiang Ren Mohan Liu Jie Xu Chunyan Dong Binyan Zhao Li Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，12： | 0 |
| 14 | Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein(RNP)to inhibit herpes simplex virus1 infection in vitro and in vivo显示文摘Extracellular vesicles(EVs)have recently emerged as a promising delivery platform for CRISPR/Cas9 ribonucleoproteins(RNPs),owing to their ability to minimize off-target effects and immune responses.However,enhancements are required to boost the efficiency and safety of Cas9 RNP enrichment within EVs.In response,we employed the Fc/Spa interaction system,in which the human Fc domain was fused to the intracellular domain of PTGFRN-Δ687 and anchored to the EV membrane.Simultaneously,the B domain of the Spa protein was fused to the C domain of cargos such as Cre or spCas9.Due to the robust interaction between Fc and Spa,this method enriched nearly twice the amount of cargo within the EVs.EVs loaded with spCas9 RNP targeting the HSV1 genome exhibited significant inhibition of viral replication in vitro and in vivo.Moreover,following neuron-targeting peptide RVG modification,the in vivo dosage in neural tissues substantially increased,contributing to the clearance of the HSV1 virus in neural tissues and exhibiting a lower off-target efficiency.These findings establish a robust platform for efficient EV-based SpCas9 delivery,offering potential therapeutic advantages for HSV1 infections and other neurological disorders. | Yuanda Wan Liren Li Ruilin Chen Jiajia Han Qiyun Lei Zhipeng Chen Xiaodong Tang Wenyu Wu Shuwen Liu Xingang Yao | 2024 | Acta Pharmaceutica Sinica B2024，14，3： | 0 |
| 15 | Venovenous extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome:A comparative cohort study in China显示文摘Background Venovenous extracorporeal membrane oxygenation(VV-ECMO)has been demonstrated to be effective in treating patients with virus-induced acute respiratory distress syndrome(ARDS).However,whether the management of ECMO is different in treating H1N1 influenza and coronavirus disease 2019(COVID-19)-associated ARDS patients remains unknown.Methods This is a retrospective cohort study.We included 12 VV-ECMO-supported COVID-19 patients admitted to The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Eighth People's Hospital,and Wuhan Union Hospital West Campus between January 23 and March 31,2020.We retrospectively included VV-ECMO-supported patients with COVID-19 and H1N1 influenza-associated ARDS.Clinical characteristics,respiratory mechanics including plateau pressure,driving pressure,mechanical power,ventilatory ratio(VR)and lung compliance,and outcomes were compared.Results Data from 25 patients with COVID-19(n=12)and H1N1(n=13)associated ARDS who had received ECMO support were analyzed.COVID-19 patients were older than H1N1 influenza patients(P=0.004).The partial pressure of arterial carbon dioxide(PaCO_(2))and VR before ECMO initiation were significantly higher in COVID-19 patients than in H1N1 influenza patients(P<0.001 and P=0.004,respectively).COVID-19 patients showed increased plateau and driving pressure compared with H1N1 subjects(P=0.013 and P=0.018,respectively).Patients with COVID-19 remained longer on ECMO support than did H1N1 influenza patients(P=0.015).COVID-19 patients who required ECMO support also had fewer intensive care unit and ventilator-free days than H1N1.Conclusions Compared with H1N1 influenza patients,COVID-19 patients were older and presented with increased PaCO_(2) and VR values before ECMO initiation.The differences between ARDS patients with COVID-19 and influenza on VV-ECMO detailed herein could be helpful for obtaining a better understanding of COVID-19 and for better clinical management. | Yonghao Xu Yin Xi Shuijiang Cai Yuheng Yu Sibei Chen Weijie Guan Weibo Liang Hongkai Wu Weiqun He Xilong Deng Yuanda Xu Rong Zhang Manshu Li Jieyi Pan Zhenting Liang Ya Wang Shaofeng Kong Xiaoqing Liu Zheng Lv Yimin Li | 2023 | Journal of Intensive Medicine2023，3，4： | 0 |
| 16 | Dynamic fluid transport property of hydraulic fractures and its evaluation using acoustic logging显示文摘The existing acoustic logging methods for evaluating the hydraulic fracturing effectiveness usually use the fracture density to evaluate the fracture volume, and the results often cannot accurately reflect the actual productivity. This paper studies the dynamic fluid flow through hydraulic fractures and its effect on borehole acoustic waves. Firstly, based on the fractal characteristics of fractures observed in hydraulic fracturing experiments, a permeability model of complex fracture network is established. Combining the dynamic fluid flow response of the model with the Biot-Rosenbaum theory that describes the acoustic wave propagation in permeable formations, the influence of hydraulic fractures on the velocity dispersion of borehole Stoneley-wave is then calculated and analyzed, whereby a novel hydraulic fracture fluid transport property evaluation method is proposed. The results show that the Stoneley-wave velocity dispersion characteristics caused by complex fractures can be equivalent to those of the plane fracture model, provided that the average permeability of the complex fracture model is equal to the permeability of the plane fracture. In addition, for fractures under high-permeability(fracture width 10~100 μm, permeability ~100 μm^(2)) and reduced permeability(1~10 μm, ~10 μm^(2), as in fracture closure) conditions, the Stoneley-wave velocity dispersion characteristics are significantly different. The field application shows that this fluid transport property evaluation method is practical to assess the permeability and the connectivity of hydraulic fractures. | LI Huanran TANG Xiaoming LI Shengqing SU Yuanda | 2022 | Petroleum Exploration and Development2022，49，1： | 0 |
| 17 | Study on Two-phase Nanocrystalline Nd_(8.5)Fe_(74)Co_5Cu_1Nb_1Zr_3Cr_1B_(6.5)Permanent Magnet显示文摘Nd8.5Fe74Co5Cu1Nb1Zr3Cr1B6.5 bonded magnets were prepared by melt-spun and subsequent heat treatment. Magnetic properties of Br=0.68T, JHc=716 kA/m, (BH)max=77 kJ/m^3 were achieved. The addition of Cr element shows to be significantly advantageous in reducing grain size and increasing the intrinsic coercivity. | Jiansen NI, Hui XU, Mingyuan ZHU, Qiang LI, Bangxin ZHOU and Yuanda DONGInstitute of Materials, Shanghai University, Shanghai 200072, China | 2004 | Journal of Materials Science & Technology2004，20，2： | 0 |
| 18 | Quasistatic and Dynamic Tensile Behavior of Zr52.5Al10Ni10Cu15Be12.5 Bulk Metallic Glass显示文摘Quasistatic and dynamic tensile behavior of Zr52.5Al10Ni10Cu15Be12.5 bulk amorphous alloy was investigated at the strain ratesof 10-4~103 s-1 by using a Shimadzu AG-100KNA autograph and a pneumatic tensile impact tester. It was shown that thetensile fracture strength and the fracture morphology were sensitive to the strain rate. With the increase of the strain rate,the tensile fracture strength decreased and the fracture morphology changed from cleavage into quasi-cleavage, and then intoa mixture of microvoid-coalescence dimples and quasi-cleavage veins. | Xueshan XIAO, Weihuo LI, Lei XIA, Shoushi FANG, Qin HUA and Yuanda DONGInstitute of Materials, Shanghai University, Shanghai 200072, China | 2003 | Journal of Materials Science & Technology2003，19，5： | 0 |
| 19 | Clipping discrete multi-tone for peak-power-constraint IM/DD optical systems显示文摘High peak-to-average power ratio(PAPR)is a major drawback of discrete multi-tone(DMT)in peak-power-constraint(PPC)intensity-modulation/direct-detection(IM/DD)optical systems.Symmetric clipping operation is a frequently-used and practical method for mitigating the PAPR of the DMT signal.However,clipping noise is inevitably induced by the symmetric clipping operation,thereby deteriorating the system’s performance.In this paper,we study the statistical characteristics of the clipping noise in detail.Depending on the statistical characteristics,clipping-noise-cancellation(CNC)algorithms are proposed to mitigate the clipping noise in the clipping DMT systems.Theoretically,the clipping noise can be completely removed using the low-density-parity-check-assisted CNC algorithm(LDPC-assisted CNC algorithm).To verify the superiority of the clipping DMT with the CNC algorithm,we conduct an experiment with a50 Gb/s DMT system using 10G-class commercial devices for the scenario of PPC passive optical networks.The receiver sensitivity of the clipping DMT system with the CNC algorithm can reach-24 d Bm at a 20%soft-decision forward-error-correction limit,which is 2.5 d B higher than that of the DMT system without clipping operation.The clipping operation and the CNC algorithm are added after the original digital signal processing,thereby demonstrating the potential to efectively overcome the drawback in DMT signals and other high-PAPR signals. | Ji ZHOU Liangchuan LI Jiale HE Xiaofeng LU Yu BO Guanyu WANG Yuanda HUANG Gengchen LIU Yanzhao LU Shecheng GAO Yuanhua FENG Shancheng ZHAO Weiping LIU Changyuan YU Zhaohui LI | 2023 | Science China(Information Sciences)2023，66，5： | 0 |
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