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| 1 | Biomechanical and biological responses of periodontium in orthodontic tooth movement:up-date in a new decade显示文摘Nowadays,orthodontic treatment has become increasingly popular.However,the biological mechanisms of orthodontic tooth movement(OTM)have not been fully elucidated.We were aiming to summarize the evidences regarding the mechanisms of OTM.Firstly,we introduced the research models as a basis for further discussion of mechanisms.Secondly,we proposed a new hypothesis regarding the primary roles of periodontal ligament cells(PDLCs)and osteocytes involved in OTM mechanisms and summarized the biomechanical and biological responses of the periodontium in OTM through four steps,basically in OTM temporal sequences,as follows:(1)Extracellular mechanobiology of periodontium:biological,mechanical,and material changes of acellular components in periodontium under orthodontic forces were introduced.(2)Cell strain:the sensing,transduction,and regulation of mechanical stimuli in PDLCs and osteocytes.(3)Cell activation and differentiation:the activation and differentiation mechanisms of osteoblast and osteoclast,the force-induced sterile inflammation,and the communication networks consisting of sensors and effectors.(4)Tissue remodeling:the remodeling of bone and periodontal ligament(PDL)in the compression side and tension side responding to mechanical stimuli and root resorption.Lastly,we talked about the clinical implications of the updated OTM mechanisms,regarding optimal orthodontic force(OOF),acceleration of OTM,and prevention of root resorption. | Yuan Li Qi Zhan Minyue Bao Jianru Yi Yu Li | 2021 | International Journal of Oral Science2021，13，2： | 15 |
| 2 | The Performance of Whole Genome Amplification Methods and Next-Generation Sequencing for Pre-Implantation Genetic Diagnosis of Chromosomal Abnormalities显示文摘Reliable and accurate pre-implantation genetic diagnosis(PGD) of patient's embryos by next-generation sequencing(NGS) is dependent on efficient whole genome amplification(WGA) of a representative biopsy sample. However, the performance of the current state of the art WGA methods has not been evaluated for sequencing. Using low template DNA(15 pg) and single cells, we showed that the two PCR-based WGA systems Sure Plex and MALBAC are superior to the REPLI-g WGA multiple displacement amplification(MDA) system in terms of consistent and reproducible genome coverage and sequence bias across the 24 chromosomes, allowing better normalization of test to reference sequencing data. When copy number variation sequencing(CNV-Seq) was applied to single cell WGA products derived by either Sure Plex or MALBAC amplification, we showed that known disease CNVs in the range of 3e15 Mb could be reliably and accurately detected at the correct genomic positions. These findings indicate that our CNV-Seq pipeline incorporating either Sure Plex or MALBAC as the key initial WGA step is a powerful methodology for clinical PGD to identify euploid embryos in a patient's cohort for uterine transplantation. | Na Li Li Wang Hui Wang Minyue Ma Xiaohong Wang Yi Li Wenke Zhang Jianguang Zhang David S.Cram Yuanqing Yao | 2015 | Journal of Genetics and Genomics2015，42，4： | 13 |
| 3 | Developing Agroforestry in Slopelands to Combat Non-point Pollution in China显示文摘The status of agricultural non-point source (NPS) pollution in China is quite austere owing to lots of factors, the characteristics of which include severe N, P eutrophications in water bodies, unsuitable structure of agriculture and the lack of reasonable management. It was well known that forest could play an important role to control soil & water erosion, uptake extra soil nutrients as well. However forest coverage is rather low in the headwaters region. The research on the causes of NSP pollution and the significance by developing agroforestry to deal with the problem is presented in the paper, as well as the function of agroforestry and the related measures of pollution controlling, e.g., riparian forest buffer zones building. As a conclusion, controlling the loss of soil and water is regarded as an important crucial action and major research direction in the field. Thereby the benefits of pushing up agroforestry in slops to combat water eutrophication and prevent NSP pollution from worsening are significant. | ZHANG Jianfeng FANG Minyu LI Sheng HE Binghui LIU Guangyan | 2007 | Chinese Forestry Science and Technology2007，6，4： | 8 |
| 4 | Effects of Carboxymethyl-Chitosan on Wound Healing in vivo and in vitro显示文摘Effects of carboxymethyl-chitosan with different molecular weights on wound healing were investigated in vivo and in vitro.A second degree burn model was performed in rats and the accelerative effects of carboxymethyl-chitosan on wound repair were observed.Contents of transforming growth factor(TGF)-β1,interleukin(IL)-6 and matrix metalloproteinase(MMP)-1 in wounds were determined by enzyme-linked immunosorbent assay(ELISA).In vitro study evaluated the influence of carboxy-methyl-chitosan on cytokines secretion of fibroblasts and macrophages.In vivo results showed that carboxymethyl-chitosan effec-tively accelerated the wound healing process in burned rats(P<0.05).Levels of TGF-β1,IL-6 and MMP-1 in carboxymethyl-chitosan groups were significantly elevated,compared with control group(P<0.05).In vitro results indicated that carboxymethyl-chitosan significantly promoted the proliferation of fibroblasts and stimulated its IL-8 and IL-10 secretion at different incubation time,but it did not affect collagen secretion of fibroblasts.Carboxymethyl-chitosan enhanced phagocytosis ability of macrophages,and in-creased its tumor necrosis factor(TNF)-α secretion.In conclusion,carboxymethyl-chitosan promoted wound healing by activating macrophages,accelerating fibroblasts growth and exerting considerable effects on the secretion of a series of cytokines. | PENG Sikai LIU Wanshun HAN Baoqin CHANG Jing LI Minyu ZHI Xuan | 2011 | Journal of Ocean University of China2011，10，4： | 7 |
| 5 | Effects of grazing disturbance of spatial distribution pattern and interspecies relationship of two desert shrubs显示文摘Grazing significantly affects the distribution,growth,and productivity of shrubs.In this study,we evalu-ated the effects of grazing disturbance on the spatial distri-bution patterns and interspecific relationships of two desert shrubs,Ammopiptanthus mongolicus and Sarcozygium xan-thoxylon.Three types of grazing conditions were considered,including enclosed area(EA),seasonal rotational grazing area(SRGA),and grazing area(GA)(100 m×100 m),in the West Ordos Nature Reserve of Inner Mongolia,China.The results showed that A.mongolicus and S.xanthoxylon populations were uniformly distributed at a small scale,and the distribution in EA and SRGA became gradually ran-dom.In GA,A.mongolicus population showed aggregated distribution but S.xanthoxylon population showed random distribution at a small scale. Moreover, both A. mongolicus and S. xanthoxylon populations at the 5-7 m scale showed random distribution. At the small and intermediate scales, the two species showed positive interspecific relationships of GA. However, no interspecific relationship was noted between the two species in EA and SRGA. A significant positive relationship (P < 0.01) was noted between the two species at 2-9 m and a negative relationship (P < 0.01) at 13-17 m scales in GA. Positive relationship (P < 0.01) was noted between the two species at 6-13 m scales and a sig-nificant negative relationship (P < 0.01) at 14-24 m scales in SRGA. The two species of desert shrubs showed posi-tive interspecific relationships at the small scale, and they showed negative relationships as the interspecific compe-tition intensified in the presence of grazing disturbance. When the grazing intensity exceeds a certain threshold, the interspecific relationships become weak. Therefore, moder-ate grazing would facilitate interspecific competition and species succession, whereas excessive grazing would disrupt natural competition causing desertification ultimately. | Lei Zhang Yong Gao Jinrong Li Chao Zhang Minyu Li Zhao Hu Xiangxin Cui | 2022 | Journal of Forestry Research2022，33，2： | 3 |
| 6 | Deriving average delay of traffic flow around intersections from vehicle trajectory data显示文摘放和无线通讯技术的进展使以一种快、方便的方式收集动人的车辆的很多轨道数据可能。数据能被用于象交通学习那样的各种各样的领域。在这份报纸,我们试图在交叉附近导出交通流动的平均延期并且与时间的变化验证结果。交叉地区首先被描出。放地理上位于这个地区以内的点被选择,然后孤立点被移开。拐弯旅行从选择轨道数据被提取。每次旅行,身体上由放的时间系列组成指,与入口道路片断和拐弯处方向被识别,即目标道路片断。拐弯旅行根据他们的时间属性被组织进不同范畴。然后,每次旅行的延期以它的记录速度在拐弯期间被计算。在时间的一样的时期的所有旅行的延期被阴谋观察交通条件的变化模式。比作常规途径,自从很多轨道数据能总是提供一个道路网络的一幅更完全的时间空间的图画,没有象循环察觉者那样的固定数据收集设备,建议方法能被用于那些交叉。关于数据可获得性,在上海的出租车轨道数据和交叉被采用测试建议方法论。结果表明它的适用性[出版摘要] | Minyue ZHAO Xiang LI | 2013 | Frontiers of Earth Science2013，7，1： | 3 |
| 7 | A strategy of screening and binding analysis of bioactive components from traditional Chinese medicine based on surface plasmon resonance biosensor显示文摘Elucidating the active components of traditional Chinese medicine(TCM)is essential for understanding the mechanisms of TCM and promote its rational use as well as TCM-derived drug development.Recent studies have shown that surface plasmon resonance(SPR)technology is promising in this field.In the present study,we propose an SPR-based integrated strategy to screen and analyze the major active components of TCM.We used Radix Paeoniae Alba(RPA)as an example to identify the compounds that can account for its anti-inflammatory mechanism via tumor necrosis factor receptor type 1(TNF-R1).First,RPA extraction was analyzed using an SPR-based screening system,and the potential active ingredients were collected,enriched,and identified as paeoniflorin and paeonol.Next,the affinity constants of paeoniflorin and paeonol were determined as 4.9 and 11.8 mM,respectively.Then,SPR-based competition assays and molecular docking were performed to show that the two compounds could compete with tumor necrosis factor-a(TNF-a)while binding to the subdomain 1 site of TNF-R1.Finally,in biological assays,the two compounds suppressed cytotoxicity and apoptosis induced by TNF-a in the L929 cell line.These findings prove that SPR technology is a useful tool for determining the active ingredients of TCM at the molecular level and can be used in various aspects of drug development.The SPR-based integrated strategy is reliable and feasible in TCM studies and will shed light on the elucidation of the pharmacological mechanism of TCM and facilitate its modernization. | Diya Lv Jin Xu Minyu Qi DongyaoWang Weiheng Xu Lei Qiu Yinghua Li Yan Cao | 2022 | Journal of Pharmaceutical Analysis2022，12，3： | 3 |
| 8 | A PGD Pregnancy Achieved by Embryo Copy Number Variation Sequencing with Confirmation by Non-Invasive Prenatal Diagnosis显示文摘Aneuploidy rates in embryos produced by assisted reproductive technologies commonly exceed 50%,particularly in couples where the woman is of advanced maternal age or has experienced repeated implantation failure(Harper et al.,2012).Pre-implantation genetic diagnosis(PGD)conducted at many fertility clinics worldwide is now | Hui Wang Li Wang Minyue Ma Zhuo Song Jianguang Zhang Genming Xu Junmei Fan Na Li David S.Cram Yuanqing Yao | 2014 | Journal of Genetics and Genomics2014，41，8： | 3 |
| 9 | Intercalation Assembly, Characterization and Luminescent Properties of Novel Supramolecular Composite Materials, Tb(Ⅲ) Complex with Tetrapodal Ligand-Montmorillonite显示文摘Two kinds of Tb(Ⅲ) complexes with tetrapodal ligand, [TbL(NO3)] 3+ and [TbL] 3+ (L: 1,1,1′,1′-tera(2-pyridinecarboxylester)-di(trimethylpropane)) were intercalated into the interlayer space of montmorillonite (MT) by ion exchange and coordination reaction of L with the Tb 3+ ion existing in the interlayer space of Tb-MT respectively. The obtained luminescent supramolecular composite materials, [TbL(NO3)] 2+ -MT and [TbL] 3+ -MT were characterized by elemental analysis, XRD, FT-IR, UV-vis and thermal analysis. At the same time, the luminescent properties of the materials were also studied. The results show that the intercalated materials with regular layered structure, good thermal stability and the interlayer spacing (d 001 ) approximates to the size of the complex ions which are located in the interlayer space of MT in the form of a monolayer. The material emit characteristic green emission of Tb 3+ strongly under excitation of ultraviolet light. It is also found that the thermal stabilities and relative luminescence intensities of the Tb 3+ species are distinctly improved after the Tb(Ⅲ) complexes are intercalated into the MT. The excitation wavelengths of the complexes are modulated to red shift in the composite materials. | Jiang Wei Tang Yu Xu Li Liu Weisheng Tan Minyu | 2006 | Journal of Rare Earths2006，24，5： | 3 |
| 10 | Preparation and characterization of nano - TiO2 powder显示文摘 | BAORANG LI XIAOHUI WANG MINYU YAN | 2001 | Materials Chemistry and Physics2001，119，： | 1 |
| 11 | A Linear Matrix Inequality Approach to Robust H∞ Filtering显示文摘 | Li Huaizhong Fu Minyue | 1997 | IEEE Transactions on Signal Processing1997，45，9： | 1 |
| 12 | Floating silver film: A flexible surface-enhanced Raman spectroscopy substrate for direct liquid phase detection at gas-liquid interfaces显示文摘在最近的年里,提高表面的拉曼光谱学(重量的单位) 很快发展了并且在液体被用于分子和 biomolecules 的察觉。然而,很少研究作为底层用水表面集中了于重量的单位。水上的一部漂浮的金属电影为提高的重量的单位表演是合乎需要的。在这个工作,银 nanoparticles (Ag NP ) 装入箱内在(vinylpyrrolidone ) poly,电影(Ag-PVP 电影) 被房间温度在一个水的答案的表面上综合电子减小。水表面上的一部漂浮的银电影从而第一次被完成并且被报导。综合 Ag-PVP 电影是为重量的单位的优秀灵活底层并且有另外的潜在的应用程序。把漂浮的银电影用作灵活重量的单位底层, 4-aminothiophenol 的 10 -11 M ,核黄素的 10 -6 M , 4-mercaptobenzoic 酸的 10 -9 M , 4-mercaptophenol 的 10 -7 M ,和 4-aminobenzoic 酸的 10 -7 M 被识别,为在分子的液体阶段察觉的漂浮的底层的示威潜在的使用。 | Zongyuan Wang Minyue Li Wei Wang Min Fang Qidi Sun Changjun Liu | 2016 | Nano Research2016，9，4： | 1 |
| 13 | Materials Preparation and characterization of nano - TiO2 powder 显示文摘 | Li Baorang Wang Xiaohui Yan Minyu | 2003 | Chemistry and Physics2003，78，13： | 1 |
| 14 | The use of poly(vinylpyridine-co-acrylonitrile)in polymer electrolytes for quasi-solid dye-sensitized solar显示文摘 | Li Minyu Feng Shujing Fang Shibi | 2007 | Electrochimica Acta:Chemistry2007，52，： | 1 |
| 15 | A Linear Matrix Inequality Approach to Robust HFiltering 显示文摘 | LI Huaizhong FU Minyue | 1997 | Signal Processing IEEETransactions on1997，45，9： | 1 |
| 16 | Generation of patient-specific pluripotent stem cells and directed differentiation of embryonic stem cells for regenerative medicine显示文摘Embryonic stem(ES) cells are pluripotent cells that can give rise to derivatives of all three embryonic germ layers. Due to its characteristics, the patient-specific ES cells are of great potential for transplantation therapies. Several strategies can reprogramme somatic cells back to pluripotent stem cells: nuclear transfer, fusion with ES cells, treatment with cell extract and induction by specific factors. Considering the future clinical use, the differentiation from ES to neurons, cardiomyocytes and many other types of cells currently provide basic cognition and experience to regenerative medicine. This article will review two courses, the reprogramming of differentiated cells and the differentiation of ES cells to specific cell types. | Minyue Ma Jiahao Sha Zuomin Zhou Qi Zhou Qingzhang Li | 2008 | Journal of Nanjing Medical University2008，22，3： | 1 |
| 17 | Preparation and characterization of nano-Ti02 powder显示文摘 | Baorang Li Xiaohui Wang Minyu Yan | 2002 | Materials Chemistry and Physics2002，78，1： | 1 |
| 18 | Quasi-solid state dye-sensitized solar cells based on pyridine or imidazole containing copolymer chemically crosslinked gel electrolytes显示文摘Quasi-solid state dye-sensitized solar cells based on chemically crosslinking with backbone polymers of poly(vinylpyridine-co-acrylonitrile) (P(VP-co-AN)) or poly(vinylimidazole-co-acrylonitrile) (P(VIM-co- AN)) and diiodide compounds of I(CH2)6I or I(CH2CH2O)nCH2CH2I solidified EC/PC/KI/I2 gel electrolytes have been fabricated. The ionic conductivities and apparent diffusion coefficients of I3? of the electro- lytes and cell performances have been investigated. Providing chemically crosslinking points, pyridine or imidazole from the backbone polymers benefited the open circuit voltage and fill factor of the cells. Consequently, the overall energy conversion efficiencies of the quasi-solid DSSCs improved over 10% even near 20% from that of the liquid electrolyte before solidification. Besides, the employing of crosslinker I(CH2CH2O)nCH2CH2I showed higher electrolytic and cell characters than that of I(CH2)6I. | LI MinYu FENG ShuJing FANG ShiBi XlAO XuRui LI XuePing ZHOU XiaoWen LIN Yuan | 2007 | Chinese Science Bulletin2007，52，17： | 0 |
| 19 | OsHG3 Affects Rice Palea Development, Grain Yield and Quality显示文摘Floral development is one of the most important determining factors of grain yield in cereal crops(Immink et al,2010).The rice inflorescence is composed of the spikelet,a specific structural unit in poaceae,which is greatly different from typical eudicots.However,several genes encoding the homologous of the proteins in ABCDE model were also found in rice genome(Luo and Zhu,2002).Lemma and palea are grass-specific floret tissues which interlock with each other to protect the inner floral organs and seeds from attack by pathogens,insects or abiotic stresses.Meanwhile,they have photosynthetic ability and provide amino acids and carbohydrates to grouting seeds. | Ouyang Linjuan Xu Minyu Hu Jiang Zhu Lixin Li Ting Xu Yilei Zhu Changlan Peng Xiaosong Chen Xiaorong He Haohua Xu Jie | 2020 | Rice science2020，27，5： | 0 |
| 20 | Comparative transcriptome analysis on candidate genes involved in lipid biosynthesis of developing kernels for three walnut cultivars in Xinjiang显示文摘Walnut(Juglans regia L.)is a good source of lipids and polyunsaturated fatty acids(PUFAs).In order to explore the biosynthesis molecular mechanism of oil accumulation and fatty acid(FA)synthesis in walnut,the samples at different development periods of three walnut cultivars,’Zhipi’(ZP),’Xinwu 417’(W417)and’Xinwen 81’(W81)were collected for transcriptomic analysis.The analysis of oil accumulation and FA profiles showed that the oil content in mature walnut kernel was nearly 70%,and over 90%of FAs were PUFAs.We identified 126 candidate genes including 64 genes for FA de novo synthesis,45 genes for triacylglycerol assembly,and 17 genes for oil bodies involved in lipid biosynthesis by RNA-sequencing.Ten key enzymes including ACCase,LACS6,LACS8,SAD,FAD2,FAD3,LPAAT1,DGAT2,PDAT2,and PLC encoded by 19 genes were highly associated with lipid biosynthesis.Quantitative PCR analysis further validated 9 important genes,and the results were well consistent with our transcriptomic data.Finally,5 important transcription factors including WRI1,ABI3,FUS3,PKL and VAL1 were identified,and their main regulatory genes might contain ACCase,KASII,LACS,FAD3 and LPAAT which were determined through correlation analysis of expression levels for 27 walnut samples.These findings will provide a comprehensive understanding and valuable information on the genetic engineering and molecular breeding in walnut. | Wenqiang Wang Hao Wen Qiang Jin Wenjun Yu Gen Li Minyu Wu Hongjin Bai Lirong Shen Cuiyun Wu | 2022 | Food Science and Human Wellness2022，11，5： | 0 |
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